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The map label for this gene is 116625770

Identifier: 116625770

GI number: 116625770

Start: 8420685

End: 8422013

Strand: Reverse

Name: 116625770

Synonym: Acid_6720

Alternate gene names: NA

Gene position: 8422013-8420685 (Counterclockwise)

Preceding gene: 116625771

Following gene: 116625769

Centisome position: 84.51

GC content: 60.95

Gene sequence:

>1329_bases
ATGAAGCGCTTTCTACTAACAGCTCTGATTGCCGCGGCGCCCCTGGCCGCTCAGATCTACGTCATCAAGAACGCCACCGT
GATGACCGTTTCCAAGGGGACCTTTAAAGGTTCCATCCTGGTGAAGGATGGCAAGATCGCCGAGCTCGGCGAGAAGGTGA
TGGAGCCGCAGGGCGCCATCATCATCGATGCCGCCAACCAATACGTGATTCCCGGTATCATCGATTGCCACTCGCACATC
GCGGGCGATGGCGGCATCAACGAGGGCTCGGTCAGCGTGTCCTCCATGGTCGATATCCGCGACATCATCAACCCCGAGGA
CATCGCGATCTATCGCGCGCTGGCGGGCGGCGTCACTACGGCGAACATTCTGCACGGCTCGGCCAACGCCATCGGCGGCA
AGACGCTGCCGCTCAAGATGCGCTGGGGCAAGGACGCGCAGGGCATGATCTTCGAAGGCGCCACGCCGGGCATCAAGTTC
GCGCTTGGTGAGAACCCCAAGCGTGCGGGCAATCCCACTGGCGGCGCGATTGGCGCAGGCGTGCCGGCTCGATACCCGGC
CACCCGCATGGGTGTAGAGGATGTGATCCGCGAGGCCTTCGTGGAGGCTAAGGCTTACAAGGCCGAGTGGGACGCATATG
ATGCCAACAAGACCGGCATTCCGCCGCGCAAAGACCTGAAGCTCGAAGCCCTCAAGGAAGTGCTGGAAGGCAAGCGCTAC
GTGCATGCCCACTCCTACCGCGCCGATGAAATCCTGATGCTGCTGCGCGTGGCCGATGAGTTCGGCTTCAAGATTCGCAC
CCTGCAGCACGTGCTCGAGGGTTATAAGGTCGCCAAGGAAATCGCCGCTCACGGGGCCGGAGCCTCCACTTTCAGCGATT
GGTGGTCTTACAAAATGGAGGCATTCGACGCCATTCCGTACAACGCCGCCATCATGCAGAAGAAGGGCGTCCTGGTGTCG
CTCAACAGCGACGACGCCGAACTGATGCGCCACCTCAACAGCGAAGCCGGGAAGGCCATGAAGTACGGCGGACTGAGCGA
AACGGAAGCCCTCGCCATGGTCACGCTCAATCCGGCCAAACAGCTCGGCATCGATAACCGTGTCGGGTCCATCGAAGTCG
GCAAGGACGCGGACCTGGTGATCTACGATAAGTTCCCGCTCTCCGACTACGCCAAAGTACAGAAGGTGCTGATCGACGGC
ACCGTGTATTTCGACCGCGACAACGAGGTCAGCAACCGGCCCACGAAAAAGGCCGACAAGCAGAAGCTGATCGATAAGGA
AAAAACGCGCGCCCCGCAGGGTGCGCCCACCAGGAGGGTCGGACAGTGA

Upstream 100 bases:

>100_bases
TGGATGGCAGAAAATATACGCCGGCGCCGGACGCCGCGCCCATGGGCGGACGCGGTCCGGCGACCGTTGATCCGGGTGTG
ATGAATCAAGGGGTGAATCA

Downstream 100 bases:

>100_bases
AATTCATTGGAATCCTGCTGAGCGGCGCGATCGCGCTTTCAGCGCAGACAGTCGTTATTCGTAACGTGGATGTTTACCCG
GTCACCGGCGCGGAGATCAA

Product: amidohydrolase

Products: D-glucosamine 6-phosphate; acetate

Alternate protein names: Amidohydrolase Family Protein; Imidazolonepropionase; Amidohydrolase Imidazolonepropionase; Dihydroorotase; Metal-Dependent Hydrolase Superfamily Protein; Amidohydrolase-Like Domain-Containing Protein; Imidazolonepropionase And Related Amidohydrolases; Metallo-Dependent Hydrolase; Amidohodrolase; Aminohydrolase; Secreted; N-Acetylglucosamine-6-Phosphate Deacetylase; Imidazolone-5-Propionate Hydrolase

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKRFLLTALIAAAPLAAQIYVIKNATVMTVSKGTFKGSILVKDGKIAELGEKVMEPQGAIIIDAANQYVIPGIIDCHSHI
AGDGGINEGSVSVSSMVDIRDIINPEDIAIYRALAGGVTTANILHGSANAIGGKTLPLKMRWGKDAQGMIFEGATPGIKF
ALGENPKRAGNPTGGAIGAGVPARYPATRMGVEDVIREAFVEAKAYKAEWDAYDANKTGIPPRKDLKLEALKEVLEGKRY
VHAHSYRADEILMLLRVADEFGFKIRTLQHVLEGYKVAKEIAAHGAGASTFSDWWSYKMEAFDAIPYNAAIMQKKGVLVS
LNSDDAELMRHLNSEAGKAMKYGGLSETEALAMVTLNPAKQLGIDNRVGSIEVGKDADLVIYDKFPLSDYAKVQKVLIDG
TVYFDRDNEVSNRPTKKADKQKLIDKEKTRAPQGAPTRRVGQ

Sequences:

>Translated_442_residues
MKRFLLTALIAAAPLAAQIYVIKNATVMTVSKGTFKGSILVKDGKIAELGEKVMEPQGAIIIDAANQYVIPGIIDCHSHI
AGDGGINEGSVSVSSMVDIRDIINPEDIAIYRALAGGVTTANILHGSANAIGGKTLPLKMRWGKDAQGMIFEGATPGIKF
ALGENPKRAGNPTGGAIGAGVPARYPATRMGVEDVIREAFVEAKAYKAEWDAYDANKTGIPPRKDLKLEALKEVLEGKRY
VHAHSYRADEILMLLRVADEFGFKIRTLQHVLEGYKVAKEIAAHGAGASTFSDWWSYKMEAFDAIPYNAAIMQKKGVLVS
LNSDDAELMRHLNSEAGKAMKYGGLSETEALAMVTLNPAKQLGIDNRVGSIEVGKDADLVIYDKFPLSDYAKVQKVLIDG
TVYFDRDNEVSNRPTKKADKQKLIDKEKTRAPQGAPTRRVGQ
>Mature_442_residues
MKRFLLTALIAAAPLAAQIYVIKNATVMTVSKGTFKGSILVKDGKIAELGEKVMEPQGAIIIDAANQYVIPGIIDCHSHI
AGDGGINEGSVSVSSMVDIRDIINPEDIAIYRALAGGVTTANILHGSANAIGGKTLPLKMRWGKDAQGMIFEGATPGIKF
ALGENPKRAGNPTGGAIGAGVPARYPATRMGVEDVIREAFVEAKAYKAEWDAYDANKTGIPPRKDLKLEALKEVLEGKRY
VHAHSYRADEILMLLRVADEFGFKIRTLQHVLEGYKVAKEIAAHGAGASTFSDWWSYKMEAFDAIPYNAAIMQKKGVLVS
LNSDDAELMRHLNSEAGKAMKYGGLSETEALAMVTLNPAKQLGIDNRVGSIEVGKDADLVIYDKFPLSDYAKVQKVLIDG
TVYFDRDNEVSNRPTKKADKQKLIDKEKTRAPQGAPTRRVGQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.1.25

Molecular weight: Translated: 47801; Mature: 47801

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFLLTALIAAAPLAAQIYVIKNATVMTVSKGTFKGSILVKDGKIAELGEKVMEPQGAI
CHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCEEEEEEEECCCHHHHHHHHHCCCCCE
IIDAANQYVIPGIIDCHSHIAGDGGINEGSVSVSSMVDIRDIINPEDIAIYRALAGGVTT
EEECCCCEECCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHCCCEE
ANILHGSANAIGGKTLPLKMRWGKDAQGMIFEGATPGIKFALGENPKRAGNPTGGAIGAG
EEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCC
VPARYPATRMGVEDVIREAFVEAKAYKAEWDAYDANKTGIPPRKDLKLEALKEVLEGKRY
CCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
VHAHSYRADEILMLLRVADEFGFKIRTLQHVLEGYKVAKEIAAHGAGASTFSDWWSYKME
EEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AFDAIPYNAAIMQKKGVLVSLNSDDAELMRHLNSEAGKAMKYGGLSETEALAMVTLNPAK
HHHCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCHH
QLGIDNRVGSIEVGKDADLVIYDKFPLSDYAKVQKVLIDGTVYFDRDNEVSNRPTKKADK
HCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHEECCEEEECCCCCCCCCCCCHHHH
QKLIDKEKTRAPQGAPTRRVGQ
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKRFLLTALIAAAPLAAQIYVIKNATVMTVSKGTFKGSILVKDGKIAELGEKVMEPQGAI
CHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCEEEEEEEECCCHHHHHHHHHCCCCCE
IIDAANQYVIPGIIDCHSHIAGDGGINEGSVSVSSMVDIRDIINPEDIAIYRALAGGVTT
EEECCCCEECCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHCCCEE
ANILHGSANAIGGKTLPLKMRWGKDAQGMIFEGATPGIKFALGENPKRAGNPTGGAIGAG
EEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCC
VPARYPATRMGVEDVIREAFVEAKAYKAEWDAYDANKTGIPPRKDLKLEALKEVLEGKRY
CCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEE
VHAHSYRADEILMLLRVADEFGFKIRTLQHVLEGYKVAKEIAAHGAGASTFSDWWSYKME
EEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AFDAIPYNAAIMQKKGVLVSLNSDDAELMRHLNSEAGKAMKYGGLSETEALAMVTLNPAK
HHHCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCHH
QLGIDNRVGSIEVGKDADLVIYDKFPLSDYAKVQKVLIDGTVYFDRDNEVSNRPTKKADK
HCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHEECCEEEECCCCCCCCCCCCHHHH
QKLIDKEKTRAPQGAPTRRVGQ
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-acetyl-D-glucosamine 6-phosphate; H2O

Specific reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA