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The map label for this gene is 116625664

Identifier: 116625664

GI number: 116625664

Start: 8298421

End: 8300070

Strand: Direct

Name: 116625664

Synonym: Acid_6613

Alternate gene names: NA

Gene position: 8298421-8300070 (Clockwise)

Preceding gene: 116625663

Following gene: 116625665

Centisome position: 83.27

GC content: 65.15

Gene sequence:

>1650_bases
GTGAAGAAGGCGGATGCAATCGTGATCGGCGCGGGCGCGGGCGGAGGCGTGGTCGCCAAGGAACTGGCGGTCGCCGGATT
GCAGGTCGTGCTGCTGGAGCGCGGGCGTTTCTACCACGCAAGCGATTGCCGCAAGGATGACCTGCGGAATCAGCGCACCT
CCATCCTGGGCAACAACACCGGGCCTGACGACGAGGGCAATCCGCGCGTGGCGGTGGACCTGGCGGGCAAATCGCACATC
GTGCGGCCCAGCCAGGGCAGCTATTCGAACAATGCCGCTTGCGTGGGCGGCGGCACGGCGACCTATGGCGCGATGGCCTG
GCGGTTTCATCCCAAAGACTTCCGCATGAAATCGGAATACGGGTGTCCGGAGGGTTCCACGCTGGACGATTGGCCGCTTA
CCTACGACGACCTGGAGCCTTACTACGAGAAGGCCGAAATCGAGATCGGCGTCTCCGGCGACGATTCCAACAATCCCTTC
AAGGGTCCGCGCAGGAAGCCGCTGCCCATGCCCCCGCTCGCGCCCACGCTCGAACATCGTATTCTCGAAGCGGCCGCCAC
GCGGCTCGGGCTGCACCCGTTCCACATTCCGATGGCGCGCAATACCGTGCCGTACAACGGGCGCCCGCCCTGCATGCGCT
GCCGCTGGTGCGTGGGCTTTTTGTGCGAGGTCAATGCCAAAGGCGGCACGCAGAATACGGTAGTACCGGCGGCACTGGCC
ACAGGGAATTGCGAGCTGCGCACCCAGGCGATGGTGCGGGAGATCCTGCTCGACGAGCGCGGCCGCGCCACCGGCGTAAT
CTATTTCGACGAGAACGATCGCCTGCAGACGCAACTGGCCGACCTGGTGGTGGTCTCCGCCTCCGCGGTGGAAACGCCGC
GCCTGCTGCTGAATTCGAAGCACCGCCTGTTCCCCAACGGACTCGGCAATCGCTACGACTGGGTGGGGCGCAACTTCCAG
GGGCACACCTACTCCGGCGCGGTCGGCAGGTTCGAGCAGGAGGTCTACGACGACCTCGGACCCGGCGCCGGGATCGCAAT
CAGCGATTTCAACCACGGCAACCCGGGATTGCGAGGCGGCGCGGCCCTGTGCAATGAATTCATCCGGCTGCCGATTCAAA
TGCAGGGCTTCCTGCCGCCCGGCACGCCGCGGTGGGGAGCGGCCAATAAGAATGCAATGCGTGCGCTCTACAAGCACACC
ATCGCCATCCAGGGTCCGACGCAGGAAATGCCGAGCTTCACTTCGCGCATCGAGGTCGATCCGACCGTGAAAGACCGCTG
GGGCATTCCGGTGGCGCGCATCTCGGGGGGCCGGCATCCGCACACGATTGAGATCGCGACGGTGATAGCCGGGAAGGCGG
CGGCGTGGCTGACCGAAGCCGGCGCCGTGCAGGTGTGGAAGCGAATTCCCGGCCAGGGCGTAAGCGGCGGACAGCATCAG
GCGGGCACCTGCCGGATGGGGAATGATCCCAGGACCTCGGTGACCAACCAGTACGGGCAGATTCACGAGGTGGCGAATGT
CTTCGTGGCGGATGGCAGCCTGCACGTCACCAACGGCGGCTTCAATCCGGCGCTGACCATCATGGCCAATGCCTACCGCG
TGTCGGACTACATTGCGAGGACGTGGAACGGCACGAGGTTCCGTTCATGA

Upstream 100 bases:

>100_bases
ACGGCGGCAATCGCGATCATTGCAGCTGGCGAATGCTGGGCGTGCCGGCGTCCCCCGTGCGCGGGCGCGACCGGTACGAC
TTCACCAAAGGCGGGCGATC

Downstream 100 bases:

>100_bases
AAGAGCGCCTGCTATTGGCCTGCGCGCTGCCGGCAATCGCCGGGCTGCTGCTGATTCCTTCCGCCGACCTTTATTACAAG
TCCTCGCGCGGCGAAGGCTG

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKKADAIVIGAGAGGGVVAKELAVAGLQVVLLERGRFYHASDCRKDDLRNQRTSILGNNTGPDDEGNPRVAVDLAGKSHI
VRPSQGSYSNNAACVGGGTATYGAMAWRFHPKDFRMKSEYGCPEGSTLDDWPLTYDDLEPYYEKAEIEIGVSGDDSNNPF
KGPRRKPLPMPPLAPTLEHRILEAAATRLGLHPFHIPMARNTVPYNGRPPCMRCRWCVGFLCEVNAKGGTQNTVVPAALA
TGNCELRTQAMVREILLDERGRATGVIYFDENDRLQTQLADLVVVSASAVETPRLLLNSKHRLFPNGLGNRYDWVGRNFQ
GHTYSGAVGRFEQEVYDDLGPGAGIAISDFNHGNPGLRGGAALCNEFIRLPIQMQGFLPPGTPRWGAANKNAMRALYKHT
IAIQGPTQEMPSFTSRIEVDPTVKDRWGIPVARISGGRHPHTIEIATVIAGKAAAWLTEAGAVQVWKRIPGQGVSGGQHQ
AGTCRMGNDPRTSVTNQYGQIHEVANVFVADGSLHVTNGGFNPALTIMANAYRVSDYIARTWNGTRFRS

Sequences:

>Translated_549_residues
MKKADAIVIGAGAGGGVVAKELAVAGLQVVLLERGRFYHASDCRKDDLRNQRTSILGNNTGPDDEGNPRVAVDLAGKSHI
VRPSQGSYSNNAACVGGGTATYGAMAWRFHPKDFRMKSEYGCPEGSTLDDWPLTYDDLEPYYEKAEIEIGVSGDDSNNPF
KGPRRKPLPMPPLAPTLEHRILEAAATRLGLHPFHIPMARNTVPYNGRPPCMRCRWCVGFLCEVNAKGGTQNTVVPAALA
TGNCELRTQAMVREILLDERGRATGVIYFDENDRLQTQLADLVVVSASAVETPRLLLNSKHRLFPNGLGNRYDWVGRNFQ
GHTYSGAVGRFEQEVYDDLGPGAGIAISDFNHGNPGLRGGAALCNEFIRLPIQMQGFLPPGTPRWGAANKNAMRALYKHT
IAIQGPTQEMPSFTSRIEVDPTVKDRWGIPVARISGGRHPHTIEIATVIAGKAAAWLTEAGAVQVWKRIPGQGVSGGQHQ
AGTCRMGNDPRTSVTNQYGQIHEVANVFVADGSLHVTNGGFNPALTIMANAYRVSDYIARTWNGTRFRS
>Mature_549_residues
MKKADAIVIGAGAGGGVVAKELAVAGLQVVLLERGRFYHASDCRKDDLRNQRTSILGNNTGPDDEGNPRVAVDLAGKSHI
VRPSQGSYSNNAACVGGGTATYGAMAWRFHPKDFRMKSEYGCPEGSTLDDWPLTYDDLEPYYEKAEIEIGVSGDDSNNPF
KGPRRKPLPMPPLAPTLEHRILEAAATRLGLHPFHIPMARNTVPYNGRPPCMRCRWCVGFLCEVNAKGGTQNTVVPAALA
TGNCELRTQAMVREILLDERGRATGVIYFDENDRLQTQLADLVVVSASAVETPRLLLNSKHRLFPNGLGNRYDWVGRNFQ
GHTYSGAVGRFEQEVYDDLGPGAGIAISDFNHGNPGLRGGAALCNEFIRLPIQMQGFLPPGTPRWGAANKNAMRALYKHT
IAIQGPTQEMPSFTSRIEVDPTVKDRWGIPVARISGGRHPHTIEIATVIAGKAAAWLTEAGAVQVWKRIPGQGVSGGQHQ
AGTCRMGNDPRTSVTNQYGQIHEVANVFVADGSLHVTNGGFNPALTIMANAYRVSDYIARTWNGTRFRS

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 59592; Mature: 59592

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKADAIVIGAGAGGGVVAKELAVAGLQVVLLERGRFYHASDCRKDDLRNQRTSILGNNT
CCCCCEEEEECCCCCCHHHHHHHHHCEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCC
GPDDEGNPRVAVDLAGKSHIVRPSQGSYSNNAACVGGGTATYGAMAWRFHPKDFRMKSEY
CCCCCCCCEEEEEECCCCEEECCCCCCCCCCEEEECCCCHHCCEEEEEECCHHCCCHHCC
GCPEGSTLDDWPLTYDDLEPYYEKAEIEIGVSGDDSNNPFKGPRRKPLPMPPLAPTLEHR
CCCCCCCCCCCCCCHHHCCHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
ILEAAATRLGLHPFHIPMARNTVPYNGRPPCMRCRWCVGFLCEVNAKGGTQNTVVPAALA
HHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCEEEEEEE
TGNCELRTQAMVREILLDERGRATGVIYFDENDRLQTQLADLVVVSASAVETPRLLLNSK
CCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHEEEEECCCCCCCHHHHCCC
HRLFPNGLGNRYDWVGRNFQGHTYSGAVGRFEQEVYDDLGPGAGIAISDFNHGNPGLRGG
CCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
AALCNEFIRLPIQMQGFLPPGTPRWGAANKNAMRALYKHTIAIQGPTQEMPSFTSRIEVD
HHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEECCHHHCCCHHHEEECC
PTVKDRWGIPVARISGGRHPHTIEIATVIAGKAAAWLTEAGAVQVWKRIPGQGVSGGQHQ
CCCHHHCCCEEEEECCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCCCCCCCCC
AGTCRMGNDPRTSVTNQYGQIHEVANVFVADGSLHVTNGGFNPALTIMANAYRVSDYIAR
CCEEECCCCCCHHHHHHHHHHHHHHEEEEECCEEEEECCCCCCEEEEEEHHHHHHHHHHH
TWNGTRFRS
CCCCCCCCC
>Mature Secondary Structure
MKKADAIVIGAGAGGGVVAKELAVAGLQVVLLERGRFYHASDCRKDDLRNQRTSILGNNT
CCCCCEEEEECCCCCCHHHHHHHHHCEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCC
GPDDEGNPRVAVDLAGKSHIVRPSQGSYSNNAACVGGGTATYGAMAWRFHPKDFRMKSEY
CCCCCCCCEEEEEECCCCEEECCCCCCCCCCEEEECCCCHHCCEEEEEECCHHCCCHHCC
GCPEGSTLDDWPLTYDDLEPYYEKAEIEIGVSGDDSNNPFKGPRRKPLPMPPLAPTLEHR
CCCCCCCCCCCCCCHHHCCHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
ILEAAATRLGLHPFHIPMARNTVPYNGRPPCMRCRWCVGFLCEVNAKGGTQNTVVPAALA
HHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCEEEEEEE
TGNCELRTQAMVREILLDERGRATGVIYFDENDRLQTQLADLVVVSASAVETPRLLLNSK
CCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHEEEEECCCCCCCHHHHCCC
HRLFPNGLGNRYDWVGRNFQGHTYSGAVGRFEQEVYDDLGPGAGIAISDFNHGNPGLRGG
CCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCH
AALCNEFIRLPIQMQGFLPPGTPRWGAANKNAMRALYKHTIAIQGPTQEMPSFTSRIEVD
HHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEECCHHHCCCHHHEEECC
PTVKDRWGIPVARISGGRHPHTIEIATVIAGKAAAWLTEAGAVQVWKRIPGQGVSGGQHQ
CCCHHHCCCEEEEECCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCCCCCCCCC
AGTCRMGNDPRTSVTNQYGQIHEVANVFVADGSLHVTNGGFNPALTIMANAYRVSDYIAR
CCEEECCCCCCHHHHHHHHHHHHHHEEEEECCEEEEECCCCCCEEEEEEHHHHHHHHHHH
TWNGTRFRS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]