Click here to switch to the map view.

The map label for this gene is iorA [H]

Identifier: 116625659

GI number: 116625659

Start: 8294153

End: 8294629

Strand: Reverse

Name: iorA [H]

Synonym: Acid_6608

Alternate gene names: 116625659

Gene position: 8294629-8294153 (Counterclockwise)

Preceding gene: 116625660

Following gene: 116625658

Centisome position: 83.23

GC content: 63.52

Gene sequence:

>477_bases
ATGGCAGCTGTTAAATTCACATTAAACGGGAAGCCGCAAACCGTGGACGTCGCACCCGCGATGCCGCTGTTGTGGGTCCT
TCGCGATACGCTCGGGATGACCGGGACCAAGTTCGGATGCGGCATGTCGCTCTGCGGCGCCTGCACCGTGCATTTGAACG
GGCAGCCCGTGCGGGCTTGCGTCACGCCCATTTCCAACGTGGCGAGCAAGACGGTCACCACGATCGAAGGCCTCTCCGCC
GACCGCGCGAACCCCATCCAGGCGGCATGGATTCAGGAAGATGTGCCGCAATGCGGGTACTGCCAGTCGGGCCAGATCAT
GACCGCCGCGGCGCTGCTGGCGAAGACCGCCAACCCCAGCGACGCCGATATCGATGAGGCCATGCGCAATAACATCTGCC
GCTGCGGCACGTACCAATCGATCCGCCGCGCGGTGCATCTTGCGGCCGAATTGCGCCGCAACGGAGGTGCAAAGTGA

Upstream 100 bases:

>100_bases
ATGGATTGCCCGCGTGTACTGCATCTCGTTACTAATCAACTGAAATCGCGGAATTGGCTATACTCGAACCAATCGTTAGC
ACTTTGAGGAGGGTTTGGGA

Downstream 100 bases:

>100_bases
GCGCTCCCCAGAACGTCAGCCGCCGCGGATTCCTGCGCGCCGGAGCCGCCGCCGCCGGCGGACTGATGATCGGCTTCCGC
ATGGGGTCCGAGGCCGTGCA

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAAVKFTLNGKPQTVDVAPAMPLLWVLRDTLGMTGTKFGCGMSLCGACTVHLNGQPVRACVTPISNVASKTVTTIEGLSA
DRANPIQAAWIQEDVPQCGYCQSGQIMTAAALLAKTANPSDADIDEAMRNNICRCGTYQSIRRAVHLAAELRRNGGAK

Sequences:

>Translated_158_residues
MAAVKFTLNGKPQTVDVAPAMPLLWVLRDTLGMTGTKFGCGMSLCGACTVHLNGQPVRACVTPISNVASKTVTTIEGLSA
DRANPIQAAWIQEDVPQCGYCQSGQIMTAAALLAKTANPSDADIDEAMRNNICRCGTYQSIRRAVHLAAELRRNGGAK
>Mature_157_residues
AAVKFTLNGKPQTVDVAPAMPLLWVLRDTLGMTGTKFGCGMSLCGACTVHLNGQPVRACVTPISNVASKTVTTIEGLSAD
RANPIQAAWIQEDVPQCGYCQSGQIMTAAALLAKTANPSDADIDEAMRNNICRCGTYQSIRRAVHLAAELRRNGGAK

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=149, Percent_Identity=35.5704697986577, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=40.7407407407407, Blast_Score=110, Evalue=4e-26,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=33.1034482758621, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=37.9084967320261, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=37.9084967320261, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=36.0759493670886, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=36.9127516778523, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647199, Length=151, Percent_Identity=32.4503311258278, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24647195, Length=159, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647197, Length=159, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647201, Length=153, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=32.5, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16692; Mature: 16561

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVKFTLNGKPQTVDVAPAMPLLWVLRDTLGMTGTKFGCGMSLCGACTVHLNGQPVRAC
CCEEEEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEEEECCCCHHHH
VTPISNVASKTVTTIEGLSADRANPIQAAWIQEDVPQCGYCQSGQIMTAAALLAKTANPS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
DADIDEAMRNNICRCGTYQSIRRAVHLAAELRRNGGAK
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAVKFTLNGKPQTVDVAPAMPLLWVLRDTLGMTGTKFGCGMSLCGACTVHLNGQPVRAC
CEEEEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCHHCCCEEEEEECCCCHHHH
VTPISNVASKTVTTIEGLSADRANPIQAAWIQEDVPQCGYCQSGQIMTAAALLAKTANPS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCC
DADIDEAMRNNICRCGTYQSIRRAVHLAAELRRNGGAK
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]