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The map label for this gene is hypB [H]

Identifier: 116625614

GI number: 116625614

Start: 8223997

End: 8224653

Strand: Direct

Name: hypB [H]

Synonym: Acid_6563

Alternate gene names: 116625614

Gene position: 8223997-8224653 (Clockwise)

Preceding gene: 116625613

Following gene: 116625615

Centisome position: 82.52

GC content: 60.58

Gene sequence:

>657_bases
GTGACGCCGCGATTGGTGGAGGTTCGCAAGAACGTTCTGAAGCGCAACGACGAACTGGCGCGCGCGCTGCGGATGCGATT
TGCGGAGGCGGGCGTCTATGTGGCGAGTCTGGTCTCGAGCCCGGGTACGGGCAAGACGGCCCTGCTGGAACGGCTGCTAA
CCGCAATGAAAACGCGGTGTCGGGTAGCCGCGCTGGTGGGCGACTTGGCAACCGAGAACGACGCCGCACGGCTCGCTCGC
AGTGGCGCGCCGGTGCGCCAGATCATCACCGGCACGGTATGCCACCTGGAAGCGCAGATGGTGGAGAAGGCGCTGGAAGG
CTGGCGGCTTGAGGACCTGGACTACCTGTTTATCGAAAACGTGGGCAATCTGGTGTGCCCCTCCAGCTACGATTTAGGGG
AAAATCTGCGCCTGGTGCTGCTATCGGTCACGGAGGGCGAAGACAAACCGCTCAAATACCCGGGGATTTTCAACACATCC
GATGTCGCGGTGGTGACGAAGTGCGATCTGGCCGATGCCGTGGAATTCGACTGGGCAGCTGCGGAGCGGAATATCCTGGC
GGTACGACCGGGAATGCGGATCGTCAAGACTTCCTCCAAGACGGGTCAAGGGCTGAACGAATTATTGGACCTGTTTTCTC
CGGTAAGTAGTTACTAA

Upstream 100 bases:

>100_bases
GTGCGAGGAGTCGCCGGTCGCGGGCGCGAGGCTGGAGATCGAGGAGGCGCGCGGGTCGGAACTGGAAGTGACCGCGTTGG
AGATTGAGGATGGCTAGGGC

Downstream 100 bases:

>100_bases
CATCAAGGAGTATCGTAGAGAACGTACTTTCGGCCTACTTCTAAACAAAGTCGTTAACTTTTTGTGCGGTCGGTGCCAGA
ATGAGAAAACGAATTGTGCC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTPRLVEVRKNVLKRNDELARALRMRFAEAGVYVASLVSSPGTGKTALLERLLTAMKTRCRVAALVGDLATENDAARLAR
SGAPVRQIITGTVCHLEAQMVEKALEGWRLEDLDYLFIENVGNLVCPSSYDLGENLRLVLLSVTEGEDKPLKYPGIFNTS
DVAVVTKCDLADAVEFDWAAAERNILAVRPGMRIVKTSSKTGQGLNELLDLFSPVSSY

Sequences:

>Translated_218_residues
MTPRLVEVRKNVLKRNDELARALRMRFAEAGVYVASLVSSPGTGKTALLERLLTAMKTRCRVAALVGDLATENDAARLAR
SGAPVRQIITGTVCHLEAQMVEKALEGWRLEDLDYLFIENVGNLVCPSSYDLGENLRLVLLSVTEGEDKPLKYPGIFNTS
DVAVVTKCDLADAVEFDWAAAERNILAVRPGMRIVKTSSKTGQGLNELLDLFSPVSSY
>Mature_217_residues
TPRLVEVRKNVLKRNDELARALRMRFAEAGVYVASLVSSPGTGKTALLERLLTAMKTRCRVAALVGDLATENDAARLARS
GAPVRQIITGTVCHLEAQMVEKALEGWRLEDLDYLFIENVGNLVCPSSYDLGENLRLVLLSVTEGEDKPLKYPGIFNTSD
VAVVTKCDLADAVEFDWAAAERNILAVRPGMRIVKTSSKTGQGLNELLDLFSPVSSY

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=207, Percent_Identity=44.9275362318841, Blast_Score=173, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23855; Mature: 23724

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRLVEVRKNVLKRNDELARALRMRFAEAGVYVASLVSSPGTGKTALLERLLTAMKTRC
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RVAALVGDLATENDAARLARSGAPVRQIITGTVCHLEAQMVEKALEGWRLEDLDYLFIEN
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
VGNLVCPSSYDLGENLRLVLLSVTEGEDKPLKYPGIFNTSDVAVVTKCDLADAVEFDWAA
CCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
AERNILAVRPGMRIVKTSSKTGQGLNELLDLFSPVSSY
CCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPRLVEVRKNVLKRNDELARALRMRFAEAGVYVASLVSSPGTGKTALLERLLTAMKTRC
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RVAALVGDLATENDAARLARSGAPVRQIITGTVCHLEAQMVEKALEGWRLEDLDYLFIEN
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
VGNLVCPSSYDLGENLRLVLLSVTEGEDKPLKYPGIFNTSDVAVVTKCDLADAVEFDWAA
CCCEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
AERNILAVRPGMRIVKTSSKTGQGLNELLDLFSPVSSY
CCCCEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]