Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 116625537

GI number: 116625537

Start: 8126755

End: 8128008

Strand: Reverse

Name: macB [H]

Synonym: Acid_6484

Alternate gene names: 116625537

Gene position: 8128008-8126755 (Counterclockwise)

Preceding gene: 116625538

Following gene: 116625536

Centisome position: 81.56

GC content: 56.46

Gene sequence:

>1254_bases
ATGGGACTTTCCAATATCGGCCCTGAATTAGTAATGGGCATGGCCAGCCTGTTTGCGCACAAGCTGCGCAGCTTGCTAAC
CATGCTCGGCATGATCTTCGGCGTGGGAGCGGTGGTGGCGATGCTTTCGATCACCGCCGGCGCGCAGAAGGAGATGATGA
GTTTCATTGACCAGTTGGGCGTCAACAACATCATTGTGGAAGCTCACGAGGCAGTAGACCGCAATGAACTGCAGACGGTG
CGTGCCGTGTCTCAGGGGCTTTCCTTCCGGGATTTCCGCGCGATCTCAGAGAACGTGTCGGGCCTGGTGGCAATCACCCC
GAGAAAGCGTTTTAAACCGCAGAAGCTGCTCCCCAAAACCAACCAGGAGCAGCCCCAGTTGATCGGCGTTTACCCGAACT
TCATGGAGATCAACAGCTTAAAGCTGGTGGAAGGCCGGTTCTTTACGGACGACGAAAACACGGCTTCGGCGCCCGTCTGC
GTACTCGGGGAGCAGACCAAGGTCAACCTGCTCGGTTACGACAAAGCCGTCGGCAAGTACGTGAAGGTCAACGATAGCTG
GCTGCAGGTGATTGGCGTTCTGACTCCGCAGGCGACCAGCGATAGCGACGTGGAAGGCGTGCAGGCGATGAACCGGAACA
ACCTGATCATCTCCCCGCTCAACACAGTAATGCGGCGCTTCGAAGACAACACCAGTTACCTGAAAGACGAAATCGACGGT
ATCTACATGAAGGTGGGTCCTAACGTAGACTCCATCGAGACGTCGAATGTGGTGCGCGCAATTCTGACCGCGACCCATAA
GGACGCTGGCGATTTTACTGTCGTGGTGCCGGCGGGTCTCCTGGAACAGAAGAAGCAGACCCAGTTCATTTTCAACGTAG
TTATGATTTGTATCGCGGGCATTTCGCTGTTGGTGGGCGGCATCGGCATCATGAACATCATGTTGGCCACGGTGCTGGAG
CGGACCCGCGAAATCGGAATTCGCCGCGCTATCGGTGCACGGCAGGGCGATATTGTCCGTCAGTTCCTCACGGAGGCGGT
GCTGATCTCGATCGTCGGTGGTTTGATCGGCATCGCGTTCGGGTTCACACTGTCCAAAGTAATTGCGTCAGTCGCCGGCT
GGTCCACCGTAGTAACCACGTCATCGATCGTGGTCGCGTTCGGCGTGTCGGTATTTATTGGGTTGTTGTTTGGGATCTAT
CCGGCCGTGCAGGCCGCGAAACTGGATCCGATCGAGGCCATTCGTTACGAGTAG

Upstream 100 bases:

>100_bases
CCGATCCTTCTCCCGATAAGAACTCCAAGAAGAACGCTGACAAAAAGTCCCAGGGTGGCGGCGGCAACCCCATGGGTGGA
ATGCCGGGGAGCAAATAGTC

Downstream 100 bases:

>100_bases
AAATATGCTGTTGCGAACTCTTATTACAGGTACACTTTTGGCGGCGGGCGCGTTTGCGCAGCTGTCCTCTTTCCCCAAGC
CGGCGTATTTCCGCGAGACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGLSNIGPELVMGMASLFAHKLRSLLTMLGMIFGVGAVVAMLSITAGAQKEMMSFIDQLGVNNIIVEAHEAVDRNELQTV
RAVSQGLSFRDFRAISENVSGLVAITPRKRFKPQKLLPKTNQEQPQLIGVYPNFMEINSLKLVEGRFFTDDENTASAPVC
VLGEQTKVNLLGYDKAVGKYVKVNDSWLQVIGVLTPQATSDSDVEGVQAMNRNNLIISPLNTVMRRFEDNTSYLKDEIDG
IYMKVGPNVDSIETSNVVRAILTATHKDAGDFTVVVPAGLLEQKKQTQFIFNVVMICIAGISLLVGGIGIMNIMLATVLE
RTREIGIRRAIGARQGDIVRQFLTEAVLISIVGGLIGIAFGFTLSKVIASVAGWSTVVTTSSIVVAFGVSVFIGLLFGIY
PAVQAAKLDPIEAIRYE

Sequences:

>Translated_417_residues
MGLSNIGPELVMGMASLFAHKLRSLLTMLGMIFGVGAVVAMLSITAGAQKEMMSFIDQLGVNNIIVEAHEAVDRNELQTV
RAVSQGLSFRDFRAISENVSGLVAITPRKRFKPQKLLPKTNQEQPQLIGVYPNFMEINSLKLVEGRFFTDDENTASAPVC
VLGEQTKVNLLGYDKAVGKYVKVNDSWLQVIGVLTPQATSDSDVEGVQAMNRNNLIISPLNTVMRRFEDNTSYLKDEIDG
IYMKVGPNVDSIETSNVVRAILTATHKDAGDFTVVVPAGLLEQKKQTQFIFNVVMICIAGISLLVGGIGIMNIMLATVLE
RTREIGIRRAIGARQGDIVRQFLTEAVLISIVGGLIGIAFGFTLSKVIASVAGWSTVVTTSSIVVAFGVSVFIGLLFGIY
PAVQAAKLDPIEAIRYE
>Mature_416_residues
GLSNIGPELVMGMASLFAHKLRSLLTMLGMIFGVGAVVAMLSITAGAQKEMMSFIDQLGVNNIIVEAHEAVDRNELQTVR
AVSQGLSFRDFRAISENVSGLVAITPRKRFKPQKLLPKTNQEQPQLIGVYPNFMEINSLKLVEGRFFTDDENTASAPVCV
LGEQTKVNLLGYDKAVGKYVKVNDSWLQVIGVLTPQATSDSDVEGVQAMNRNNLIISPLNTVMRRFEDNTSYLKDEIDGI
YMKVGPNVDSIETSNVVRAILTATHKDAGDFTVVVPAGLLEQKKQTQFIFNVVMICIAGISLLVGGIGIMNIMLATVLER
TREIGIRRAIGARQGDIVRQFLTEAVLISIVGGLIGIAFGFTLSKVIASVAGWSTVVTTSSIVVAFGVSVFIGLLFGIYP
AVQAAKLDPIEAIRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=430, Percent_Identity=31.6279069767442, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45171; Mature: 45040

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSNIGPELVMGMASLFAHKLRSLLTMLGMIFGVGAVVAMLSITAGAQKEMMSFIDQLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
VNNIIVEAHEAVDRNELQTVRAVSQGLSFRDFRAISENVSGLVAITPRKRFKPQKLLPKT
CCCEEEEHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHCCCHHCCCCC
NQEQPQLIGVYPNFMEINSLKLVEGRFFTDDENTASAPVCVLGEQTKVNLLGYDKAVGKY
CCCCCCEEEECCCCEEECCEEEECCEEECCCCCCCCCCEEEECCCCEEEEEECHHHHCCE
VKVNDSWLQVIGVLTPQATSDSDVEGVQAMNRNNLIISPLNTVMRRFEDNTSYLKDEIDG
EEECHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHHCE
IYMKVGPNVDSIETSNVVRAILTATHKDAGDFTVVVPAGLLEQKKQTQFIFNVVMICIAG
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ISLLVGGIGIMNIMLATVLERTREIGIRRAIGARQGDIVRQFLTEAVLISIVGGLIGIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GFTLSKVIASVAGWSTVVTTSSIVVAFGVSVFIGLLFGIYPAVQAAKLDPIEAIRYE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
GLSNIGPELVMGMASLFAHKLRSLLTMLGMIFGVGAVVAMLSITAGAQKEMMSFIDQLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
VNNIIVEAHEAVDRNELQTVRAVSQGLSFRDFRAISENVSGLVAITPRKRFKPQKLLPKT
CCCEEEEHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHCCCHHCCCCC
NQEQPQLIGVYPNFMEINSLKLVEGRFFTDDENTASAPVCVLGEQTKVNLLGYDKAVGKY
CCCCCCEEEECCCCEEECCEEEECCEEECCCCCCCCCCEEEECCCCEEEEEECHHHHCCE
VKVNDSWLQVIGVLTPQATSDSDVEGVQAMNRNNLIISPLNTVMRRFEDNTSYLKDEIDG
EEECHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHHCE
IYMKVGPNVDSIETSNVVRAILTATHKDAGDFTVVVPAGLLEQKKQTQFIFNVVMICIAG
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
ISLLVGGIGIMNIMLATVLERTREIGIRRAIGARQGDIVRQFLTEAVLISIVGGLIGIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GFTLSKVIASVAGWSTVVTTSSIVVAFGVSVFIGLLFGIYPAVQAAKLDPIEAIRYE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA