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The map label for this gene is czcB [H]

Identifier: 116625507

GI number: 116625507

Start: 8088827

End: 8089999

Strand: Direct

Name: czcB [H]

Synonym: Acid_6454

Alternate gene names: 116625507

Gene position: 8088827-8089999 (Clockwise)

Preceding gene: 116625506

Following gene: 116625508

Centisome position: 81.17

GC content: 64.28

Gene sequence:

>1173_bases
ATGAAAAACGTACACGCGAGTTGCGCTCTTATCCTATCGATCCTGGCGATTCTGTTGACCGGATGTGCGAAGCAAGAGGC
GAAGCCGGTGGCGGCGGCTGCTCCGGCCGGGGAAGAGCGGCAGGCGGATGGCACGGTGGTCATTCCGGCGGATTCACCGA
AGCTGAAGGAGATCCACGTGGCGGAAGTGGGGACGGCGTCGGTGCCGTCAGCCGAGGTGACTTCGCCGGGGAAAATCGAG
GCCAATCCGAACCTCATGTCGCGGGTGGCGTTGCCGCTCGCGGGGCGCGTCTCCTCGGTGCTGGTGAAGCTGGGCGATTC
AGTGGAGCGCGGGCAGACGCTGCTGACTCTGGAATCGCCGGACGCGGACGCGGGCGAGGCCGCGTACCTGCAAGCCCAGG
CCGCGATCACGCAGGCGAAGGCCAACCTGAACAAGGCGCAGGCCGATTACGACCGCGCATCCGATTTGTTCGAGCACAAT
GCGGTGGCCAAGAAGGATGTGCTCACCGCGGAGAATGCGCTCGCACAAGCGAAATCCGCGCTGGAGCAGTCACAGGCAGG
GCTGGAACAATCGGAGCGCAAGCTGCGCATGCTCGGGCTTAAGCCTGGGACTTTCGGGCAGAAGGTAACGGTGAGCGCAC
CGATATCCGGCAAGATCCTGGACATGAGCGTGGCGGCAGGCGAATATCGCAACGATACCAACGCGCCGCTGATGACGATT
GCGGACCTGAGCAGCGTGTGGGTCTCCTCCGATGTGCCGGAGAGCGCTATCCGCTTTGTGGCACCCGGTGAGCGGATCGA
CGTGGAATTGACGGCGTACCCCGGGGTGACCTTCCACGGCAAGGTGACGCGCATCGCCGACGTGGTGGACCCACAGACAC
GGACGATCAAAGTCCGCGCCGAAATGGATAACGCAAGCGGGAAACTGCGTCCCGAGATGTATGGCACGATCCGCCACACC
GAAGCGATGAAGACGCTGCCGGTGGTGCCGGCCGGCGCGGTGCTCCAAGGCGACGGCAAGACCAGCGTGTGGGTGGAGCG
GGCGCCTGGGCGTTTCCAACCAGTGGAGGTAAAGGTCGGTGAGCGTGCAGGAAACATGCTGCCGGTGTTGAGCGGGTTGA
AAGCGGGAACACGCATCGTGGCCGACGGCGCGATGCTGCTGCGGGCCCAGTAG

Upstream 100 bases:

>100_bases
AGCGCGCCTTCAACGACGCGCGGCAAAGTTACAACGACGCGCGCGCGGACTTTGCACGCAGTCTCTACACGATCGATTCG
ATCTCTGGAAAGGCAGTCCG

Downstream 100 bases:

>100_bases
GGATCTCATGATAGCCAAACTACTGCGGTTCGCATTAGCGCAACGCTTCGTGATGATTGTGCTCTCGCTCGGCCTGATCG
GGCTGGGTATCTACAGCTTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKNVHASCALILSILAILLTGCAKQEAKPVAAAAPAGEERQADGTVVIPADSPKLKEIHVAEVGTASVPSAEVTSPGKIE
ANPNLMSRVALPLAGRVSSVLVKLGDSVERGQTLLTLESPDADAGEAAYLQAQAAITQAKANLNKAQADYDRASDLFEHN
AVAKKDVLTAENALAQAKSALEQSQAGLEQSERKLRMLGLKPGTFGQKVTVSAPISGKILDMSVAAGEYRNDTNAPLMTI
ADLSSVWVSSDVPESAIRFVAPGERIDVELTAYPGVTFHGKVTRIADVVDPQTRTIKVRAEMDNASGKLRPEMYGTIRHT
EAMKTLPVVPAGAVLQGDGKTSVWVERAPGRFQPVEVKVGERAGNMLPVLSGLKAGTRIVADGAMLLRAQ

Sequences:

>Translated_390_residues
MKNVHASCALILSILAILLTGCAKQEAKPVAAAAPAGEERQADGTVVIPADSPKLKEIHVAEVGTASVPSAEVTSPGKIE
ANPNLMSRVALPLAGRVSSVLVKLGDSVERGQTLLTLESPDADAGEAAYLQAQAAITQAKANLNKAQADYDRASDLFEHN
AVAKKDVLTAENALAQAKSALEQSQAGLEQSERKLRMLGLKPGTFGQKVTVSAPISGKILDMSVAAGEYRNDTNAPLMTI
ADLSSVWVSSDVPESAIRFVAPGERIDVELTAYPGVTFHGKVTRIADVVDPQTRTIKVRAEMDNASGKLRPEMYGTIRHT
EAMKTLPVVPAGAVLQGDGKTSVWVERAPGRFQPVEVKVGERAGNMLPVLSGLKAGTRIVADGAMLLRAQ
>Mature_390_residues
MKNVHASCALILSILAILLTGCAKQEAKPVAAAAPAGEERQADGTVVIPADSPKLKEIHVAEVGTASVPSAEVTSPGKIE
ANPNLMSRVALPLAGRVSSVLVKLGDSVERGQTLLTLESPDADAGEAAYLQAQAAITQAKANLNKAQADYDRASDLFEHN
AVAKKDVLTAENALAQAKSALEQSQAGLEQSERKLRMLGLKPGTFGQKVTVSAPISGKILDMSVAAGEYRNDTNAPLMTI
ADLSSVWVSSDVPESAIRFVAPGERIDVELTAYPGVTFHGKVTRIADVVDPQTRTIKVRAEMDNASGKLRPEMYGTIRHT
EAMKTLPVVPAGAVLQGDGKTSVWVERAPGRFQPVEVKVGERAGNMLPVLSGLKAGTRIVADGAMLLRAQ

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=361, Percent_Identity=24.6537396121884, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081796, Length=320, Percent_Identity=24.375, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789929, Length=301, Percent_Identity=24.9169435215947, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40991; Mature: 40991

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVHASCALILSILAILLTGCAKQEAKPVAAAAPAGEERQADGTVVIPADSPKLKEIHV
CCCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCEEEE
AEVGTASVPSAEVTSPGKIEANPNLMSRVALPLAGRVSSVLVKLGDSVERGQTLLTLESP
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCHHCCCEEEEEECC
DADAGEAAYLQAQAAITQAKANLNKAQADYDRASDLFEHNAVAKKDVLTAENALAQAKSA
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LEQSQAGLEQSERKLRMLGLKPGTFGQKVTVSAPISGKILDMSVAAGEYRNDTNAPLMTI
HHHHHHCHHHHHHHEEEEECCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEE
ADLSSVWVSSDVPESAIRFVAPGERIDVELTAYPGVTFHGKVTRIADVVDPQTRTIKVRA
EHHHHHHHCCCCCHHHHEEECCCCEEEEEEEECCCEEECCCHHHHHHHCCCCCEEEEEEE
EMDNASGKLRPEMYGTIRHTEAMKTLPVVPAGAVLQGDGKTSVWVERAPGRFQPVEVKVG
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEEC
ERAGNMLPVLSGLKAGTRIVADGAMLLRAQ
CCCCCCHHHHHCCCCCCEEEECCEEEEECC
>Mature Secondary Structure
MKNVHASCALILSILAILLTGCAKQEAKPVAAAAPAGEERQADGTVVIPADSPKLKEIHV
CCCCHHHHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCEEEE
AEVGTASVPSAEVTSPGKIEANPNLMSRVALPLAGRVSSVLVKLGDSVERGQTLLTLESP
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCHHCCCEEEEEECC
DADAGEAAYLQAQAAITQAKANLNKAQADYDRASDLFEHNAVAKKDVLTAENALAQAKSA
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LEQSQAGLEQSERKLRMLGLKPGTFGQKVTVSAPISGKILDMSVAAGEYRNDTNAPLMTI
HHHHHHCHHHHHHHEEEEECCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEE
ADLSSVWVSSDVPESAIRFVAPGERIDVELTAYPGVTFHGKVTRIADVVDPQTRTIKVRA
EHHHHHHHCCCCCHHHHEEECCCCEEEEEEEECCCEEECCCHHHHHHHCCCCCEEEEEEE
EMDNASGKLRPEMYGTIRHTEAMKTLPVVPAGAVLQGDGKTSVWVERAPGRFQPVEVKVG
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEEC
ERAGNMLPVLSGLKAGTRIVADGAMLLRAQ
CCCCCCHHHHHCCCCCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]