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The map label for this gene is tnaA [H]

Identifier: 116625424

GI number: 116625424

Start: 7988149

End: 7989495

Strand: Direct

Name: tnaA [H]

Synonym: Acid_6369

Alternate gene names: 116625424

Gene position: 7988149-7989495 (Clockwise)

Preceding gene: 116625423

Following gene: 116625427

Centisome position: 80.16

GC content: 64.51

Gene sequence:

>1347_bases
GTGCGCACCATCATCGAACCCTTCCGCATCAAGAGCGTGGAACCGCTGCACCACACCACTCCCGCGGAACGCGAGCGCTA
TCTCGCCAACGCAGGCTACAACCTCTTCCTCATTGACGCCCGCCACATTCTGATCGATCTGCTCACCGACTCCGGCACCA
GCGCCATGTCCAACGCGCAATGGGCCGCGATCATGCGCGGCGACGAAAGCTACGCCGGCAGCGAGAGCTTCTTCCGCCTG
AAGCGCGTCGCCGACGAACTCACCGGCTTCCGCCACATGGTTCCCACTCACCAGGGCCGCGCCGCCGAGCGCATCCTCTT
CACGGTGATGTGCAAGCCCGGCGACGTGATCCCCTCCAACACACATTTCGATACCACCCGGGCCAACGTCGAATTCACCG
GGGCCCGGGCCGTCGATCTCCCTATACCCGAAGCCCGCGACACCCAGGCCCGCCTGGATTTCAAAGGGAATATGGATGTC
CCCGCGCTCGAGGCCCTGATCTCCGCCGAGGGCGCGGCCAAGATCCCCCTCGTGATGCTGACCGTCACCAACAACTCCGG
CGGCGGCCAGCCCGTTTCACTGGCCAACATCGGCGCTGTCAAGGACGTCTGCGCACGCCACCGCATCCCGCTCTACCTCG
ACGCCTGCCGCTTCGCCGAAAACGCCTGGTTCATCCACCAGCGCGAGCCCGGCTACCAGGACTGGTCGCCAAAGCAAATC
GCCCAGAAAATGTTTTCACTCGCCGATGGCGCCACCTTCTCCGCCAAGAAGGACGCCTTCGCCAACATCGGCGGCCTGCT
CTTCAGCAACGACGAGCGGGTCTTCCAGCAGGAGACCAACCTCCTCATCCTCACCGAAGGCTTCCCGACCTACGGAGGGC
TCGCCGGCCGCGATCTCGACGCCATCGCCGTCGGCCTGGAAGAAATCCTCGACCCCGATTACCTCAACTACCGCATTGTC
TCCACCGGCTATCTTGGCCGCCACATCGCCGACCATGGCGTCCCCATCGTCGAGCCGCCCGGCGGCCACGCCATCTATAT
CGATGCCGCGCGCATGCTCCCCCATATCCCCCCGCAACAGTTCCCCGGCCAGGCCCTCGCGGTGGAGCTCTACCGCCACG
CCGGAATCCGTGGCGTCGAAATCGGCAGCCTTATGTTCGCGGGAGCCGCCCAGCACGAATTGCTCCGCCTCGCCATCCCA
CGCCGCGTCTACACCCAGAGCCACATCGATTACGTGGTGGAAGCGATCCTCGAGGTCAACGCGAACAAGAACGCAATCCG
CGGTATGGAAATCGTCGAAGCCCCGCCCTTCCTGCGCCACTTCAGCGCACGGATGAGGCAGCTATAG

Upstream 100 bases:

>100_bases
GAGCTCTACATCACCGCCGACGGCGTGGAAAGCAACCGCGTCCAAATCACGATAGACCAATAGGACCGGCCTGCTGGCCC
GGCCTGCTACTCTGTGTGTC

Downstream 100 bases:

>100_bases
AGGCGTGAGATTCGAAGTAATTTTTTAGCGATTGATCAGCGCCGGTCTTCGGGAGCGGGCTCAGCGGACGGGACCTTGTC
CAGCGCGGCCAGGAAACGCT

Product: tryptophanase

Products: NA

Alternate protein names: L-tryptophan indole-lyase; TNase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRTIIEPFRIKSVEPLHHTTPAERERYLANAGYNLFLIDARHILIDLLTDSGTSAMSNAQWAAIMRGDESYAGSESFFRL
KRVADELTGFRHMVPTHQGRAAERILFTVMCKPGDVIPSNTHFDTTRANVEFTGARAVDLPIPEARDTQARLDFKGNMDV
PALEALISAEGAAKIPLVMLTVTNNSGGGQPVSLANIGAVKDVCARHRIPLYLDACRFAENAWFIHQREPGYQDWSPKQI
AQKMFSLADGATFSAKKDAFANIGGLLFSNDERVFQQETNLLILTEGFPTYGGLAGRDLDAIAVGLEEILDPDYLNYRIV
STGYLGRHIADHGVPIVEPPGGHAIYIDAARMLPHIPPQQFPGQALAVELYRHAGIRGVEIGSLMFAGAAQHELLRLAIP
RRVYTQSHIDYVVEAILEVNANKNAIRGMEIVEAPPFLRHFSARMRQL

Sequences:

>Translated_448_residues
MRTIIEPFRIKSVEPLHHTTPAERERYLANAGYNLFLIDARHILIDLLTDSGTSAMSNAQWAAIMRGDESYAGSESFFRL
KRVADELTGFRHMVPTHQGRAAERILFTVMCKPGDVIPSNTHFDTTRANVEFTGARAVDLPIPEARDTQARLDFKGNMDV
PALEALISAEGAAKIPLVMLTVTNNSGGGQPVSLANIGAVKDVCARHRIPLYLDACRFAENAWFIHQREPGYQDWSPKQI
AQKMFSLADGATFSAKKDAFANIGGLLFSNDERVFQQETNLLILTEGFPTYGGLAGRDLDAIAVGLEEILDPDYLNYRIV
STGYLGRHIADHGVPIVEPPGGHAIYIDAARMLPHIPPQQFPGQALAVELYRHAGIRGVEIGSLMFAGAAQHELLRLAIP
RRVYTQSHIDYVVEAILEVNANKNAIRGMEIVEAPPFLRHFSARMRQL
>Mature_448_residues
MRTIIEPFRIKSVEPLHHTTPAERERYLANAGYNLFLIDARHILIDLLTDSGTSAMSNAQWAAIMRGDESYAGSESFFRL
KRVADELTGFRHMVPTHQGRAAERILFTVMCKPGDVIPSNTHFDTTRANVEFTGARAVDLPIPEARDTQARLDFKGNMDV
PALEALISAEGAAKIPLVMLTVTNNSGGGQPVSLANIGAVKDVCARHRIPLYLDACRFAENAWFIHQREPGYQDWSPKQI
AQKMFSLADGATFSAKKDAFANIGGLLFSNDERVFQQETNLLILTEGFPTYGGLAGRDLDAIAVGLEEILDPDYLNYRIV
STGYLGRHIADHGVPIVEPPGGHAIYIDAARMLPHIPPQQFPGQALAVELYRHAGIRGVEIGSLMFAGAAQHELLRLAIP
RRVYTQSHIDYVVEAILEVNANKNAIRGMEIVEAPPFLRHFSARMRQL

Specific function: Tryptophan catabolism. [C]

COG id: COG3033

COG function: function code E; Tryptophanase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-eliminating lyase family [H]

Homologues:

Organism=Escherichia coli, GI87082323, Length=464, Percent_Identity=43.75, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: 7160 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 460 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011166 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.99.1 [H]

Molecular weight: Translated: 49531; Mature: 49531

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIIEPFRIKSVEPLHHTTPAERERYLANAGYNLFLIDARHILIDLLTDSGTSAMSNAQ
CCCCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEHHEEEEEECCCCCCCHHCCCC
WAAIMRGDESYAGSESFFRLKRVADELTGFRHMVPTHQGRAAERILFTVMCKPGDVIPSN
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCCCCC
THFDTTRANVEFTGARAVDLPIPEARDTQARLDFKGNMDVPALEALISAEGAAKIPLVML
CCCCCEECEEEECCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEE
TVTNNSGGGQPVSLANIGAVKDVCARHRIPLYLDACRFAENAWFIHQREPGYQDWSPKQI
EEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEHHHHHCCCEEEEEECCCCCCCCCHHHH
AQKMFSLADGATFSAKKDAFANIGGLLFSNDERVFQQETNLLILTEGFPTYGGLAGRDLD
HHHHHHHHCCCCCCCCHHHHHHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCHH
AIAVGLEEILDPDYLNYRIVSTGYLGRHIADHGVPIVEPPGGHAIYIDAARMLPHIPPQQ
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCEEEECCCCCEEEEEHHHHCCCCCCCC
FPGQALAVELYRHAGIRGVEIGSLMFAGAAQHELLRLAIPRRVYTQSHIDYVVEAILEVN
CCCHHHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
ANKNAIRGMEIVEAPPFLRHFSARMRQL
CCCCHHCCCEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRTIIEPFRIKSVEPLHHTTPAERERYLANAGYNLFLIDARHILIDLLTDSGTSAMSNAQ
CCCCCCCHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEHHEEEEEECCCCCCCHHCCCC
WAAIMRGDESYAGSESFFRLKRVADELTGFRHMVPTHQGRAAERILFTVMCKPGDVIPSN
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEECCCCCCCCC
THFDTTRANVEFTGARAVDLPIPEARDTQARLDFKGNMDVPALEALISAEGAAKIPLVML
CCCCCEECEEEECCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEE
TVTNNSGGGQPVSLANIGAVKDVCARHRIPLYLDACRFAENAWFIHQREPGYQDWSPKQI
EEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEHHHHHCCCEEEEEECCCCCCCCCHHHH
AQKMFSLADGATFSAKKDAFANIGGLLFSNDERVFQQETNLLILTEGFPTYGGLAGRDLD
HHHHHHHHCCCCCCCCHHHHHHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCHH
AIAVGLEEILDPDYLNYRIVSTGYLGRHIADHGVPIVEPPGGHAIYIDAARMLPHIPPQQ
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCEEEECCCCCEEEEEHHHHCCCCCCCC
FPGQALAVELYRHAGIRGVEIGSLMFAGAAQHELLRLAIPRRVYTQSHIDYVVEAILEVN
CCCHHHHHHHHHHCCCCEEEECHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
ANKNAIRGMEIVEAPPFLRHFSARMRQL
CCCCHHCCCEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA