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The map label for this gene is qheDH [H]

Identifier: 116625397

GI number: 116625397

Start: 7959671

End: 7961248

Strand: Reverse

Name: qheDH [H]

Synonym: Acid_6342

Alternate gene names: 116625397

Gene position: 7961248-7959671 (Counterclockwise)

Preceding gene: 116625398

Following gene: 116625395

Centisome position: 79.89

GC content: 64.51

Gene sequence:

>1578_bases
ATGAGAGTCCTCGCCACTTTTCTTCTCGCTTGCGGCGCCGTGTCGGCGCAGGGCGGTTTGAATCCCGCCAAACTCGGCGC
ACCGCCCACCGATACCTGGCCCACCTACAACGGCGACTACACGGGCCGGCGCTACAGCACCCTCTCCAAGATCAACCAGG
GGAACATCAATTCGCTGAGCCTGGCGTGGGTCTACCGCGCCAACGGAGCCCTCGGCTCGGGCCCTCCCGGAGGCCGCATT
TCCTCCACTCCCGTGCAGGTCAACGGCGTCCTGTACTTCACCATGCCCGACCACGCCTGGGCGGTGGACGCGCGCACCGG
CCGCGAGGTCTGGCACTTCCGTTGGACGTCGCACGGCGGCGAACACATCGGCAATCGCGGCGCGGGCGTCTACGGCAACT
GGCTCTACTTCCTCACGCCGGATTGCAACATGGTCTCGTTGAATCTGAAGGACGGCAGCGAGCGCTGGCGCACGTCGGTC
TGCGACCTGGACCAGTACTACTTCGGCTCCATGGCCCCGCTGGTGGTCAAGAATCACATCATCACCGGCGTGAGCGGCGA
CGATCTGGACCGCCCCGGCTACATCGAAGCGCACGATCCGGAGACGGGCGCGCTGCAATGGCGCTGGTACACGGTCCCAC
AGAAGATGGGCGATCCCGGGTCGGAGACCTGGCCGAATGAAGAGGCGATGAAGCACGGCGGCGGCATGACGTGGCTGACG
CCCACGTACGATCCCGAATTGAACATGATCTACGTGCCTACCGGTAATCCGCAGCCGGTAATCGCGGGCAAGGCGCGGCC
GGGCGCGAACCTGTTCACCGCGTCGGTGGTGGCGCTGAATCCCGACACCGGCAAAATGCAGTGGTATTTCCAGAGCTCGC
CGCACGACACGCATGATTGGGACGCGACCCAGACGCCCGTGCTGTTCGACGCCGAGATCGACGGGAAAAAGCGCAAGATC
GTGGCCCAGGCGAGCCGCAACGGCTATTTCTTCGCCATCGACCGGGCAACCGGCAAGAACATCGTGAGCGCCGAATACGT
CAAGGGGAACTGGTCGAAGGGCGTGGACGCGAAGGGTTCGCCGATTCCGAATCCCGAGAAGGAACCGCAGCTCGATGGCG
CCCTGGTCTCACCCAACCAGGGAGGCGGCACTAACTGGCCGCCGCCGACCTACAATCCGGACACCGGCCTGTTCTACGTG
AACGCCTCGCGCGCGTTCAGCGTGTACTACATTTACGACCCGAGCGATAAGCCCGAAGGCTGGGGCGGCAACGACCGCGG
CGGCTGGGGCGAAGCCATGATCCAGGCGATCGATCCGAAGACCGGAAAGGTGAAATGGACCCACAAGTGGGAGGATGGCT
CGCGCGGCGGTTTGCTCTCCACGGCCGGCAAGCTCCTGTTCGGTGGCGACGGCTCCGGGAACCTGGTGGCGCTCGACCCC
GCTAACGGAAACCCGCTATGGCACGCGAACCTGGGAAATTCGGTAACCAACGGCCCCATCACCTACGAGCTCGACGGCAC
CCAATATCTGGTAGTCGGCGCCGGCGACACCCTATACGGTTTCGCGATGTTGCGCTAG

Upstream 100 bases:

>100_bases
AGGTCGTGAAGAACGATCCCCTGCAGGCGCATCACGAACTGCTGGATCGCTACACCGACAAAAACATGCACGACATCGTC
GCCTACCTGGAGACCCTGAA

Downstream 100 bases:

>100_bases
CGGAGTCAACGAGCCGCGACCGTGAGCGTCCGCCTCGTCGTCGTCAACGACCCGTTGTCCGCTCGCGGCCCGCAAACAAC
TCGCCGGGTCAACGAGCCGC

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRVLATFLLACGAVSAQGGLNPAKLGAPPTDTWPTYNGDYTGRRYSTLSKINQGNINSLSLAWVYRANGALGSGPPGGRI
SSTPVQVNGVLYFTMPDHAWAVDARTGREVWHFRWTSHGGEHIGNRGAGVYGNWLYFLTPDCNMVSLNLKDGSERWRTSV
CDLDQYYFGSMAPLVVKNHIITGVSGDDLDRPGYIEAHDPETGALQWRWYTVPQKMGDPGSETWPNEEAMKHGGGMTWLT
PTYDPELNMIYVPTGNPQPVIAGKARPGANLFTASVVALNPDTGKMQWYFQSSPHDTHDWDATQTPVLFDAEIDGKKRKI
VAQASRNGYFFAIDRATGKNIVSAEYVKGNWSKGVDAKGSPIPNPEKEPQLDGALVSPNQGGGTNWPPPTYNPDTGLFYV
NASRAFSVYYIYDPSDKPEGWGGNDRGGWGEAMIQAIDPKTGKVKWTHKWEDGSRGGLLSTAGKLLFGGDGSGNLVALDP
ANGNPLWHANLGNSVTNGPITYELDGTQYLVVGAGDTLYGFAMLR

Sequences:

>Translated_525_residues
MRVLATFLLACGAVSAQGGLNPAKLGAPPTDTWPTYNGDYTGRRYSTLSKINQGNINSLSLAWVYRANGALGSGPPGGRI
SSTPVQVNGVLYFTMPDHAWAVDARTGREVWHFRWTSHGGEHIGNRGAGVYGNWLYFLTPDCNMVSLNLKDGSERWRTSV
CDLDQYYFGSMAPLVVKNHIITGVSGDDLDRPGYIEAHDPETGALQWRWYTVPQKMGDPGSETWPNEEAMKHGGGMTWLT
PTYDPELNMIYVPTGNPQPVIAGKARPGANLFTASVVALNPDTGKMQWYFQSSPHDTHDWDATQTPVLFDAEIDGKKRKI
VAQASRNGYFFAIDRATGKNIVSAEYVKGNWSKGVDAKGSPIPNPEKEPQLDGALVSPNQGGGTNWPPPTYNPDTGLFYV
NASRAFSVYYIYDPSDKPEGWGGNDRGGWGEAMIQAIDPKTGKVKWTHKWEDGSRGGLLSTAGKLLFGGDGSGNLVALDP
ANGNPLWHANLGNSVTNGPITYELDGTQYLVVGAGDTLYGFAMLR
>Mature_525_residues
MRVLATFLLACGAVSAQGGLNPAKLGAPPTDTWPTYNGDYTGRRYSTLSKINQGNINSLSLAWVYRANGALGSGPPGGRI
SSTPVQVNGVLYFTMPDHAWAVDARTGREVWHFRWTSHGGEHIGNRGAGVYGNWLYFLTPDCNMVSLNLKDGSERWRTSV
CDLDQYYFGSMAPLVVKNHIITGVSGDDLDRPGYIEAHDPETGALQWRWYTVPQKMGDPGSETWPNEEAMKHGGGMTWLT
PTYDPELNMIYVPTGNPQPVIAGKARPGANLFTASVVALNPDTGKMQWYFQSSPHDTHDWDATQTPVLFDAEIDGKKRKI
VAQASRNGYFFAIDRATGKNIVSAEYVKGNWSKGVDAKGSPIPNPEKEPQLDGALVSPNQGGGTNWPPPTYNPDTGLFYV
NASRAFSVYYIYDPSDKPEGWGGNDRGGWGEAMIQAIDPKTGKVKWTHKWEDGSRGGLLSTAGKLLFGGDGSGNLVALDP
ANGNPLWHANLGNSVTNGPITYELDGTQYLVVGAGDTLYGFAMLR

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=375, Percent_Identity=26.9333333333333, Blast_Score=125, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 56989; Mature: 56989

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLATFLLACGAVSAQGGLNPAKLGAPPTDTWPTYNGDYTGRRYSTLSKINQGNINSLS
CHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEE
LAWVYRANGALGSGPPGGRISSTPVQVNGVLYFTMPDHAWAVDARTGREVWHFRWTSHGG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCEEEEEEECCCCC
EHIGNRGAGVYGNWLYFLTPDCNMVSLNLKDGSERWRTSVCDLDQYYFGSMAPLVVKNHI
HHCCCCCCCEEECEEEEECCCCCEEEEECCCCHHHHHHHHHCCHHHHHCCCCCEEEECEE
ITGVSGDDLDRPGYIEAHDPETGALQWRWYTVPQKMGDPGSETWPNEEAMKHGGGMTWLT
EECCCCCCCCCCCEEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHCCCEEEEC
PTYDPELNMIYVPTGNPQPVIAGKARPGANLFTASVVALNPDTGKMQWYFQSSPHDTHDW
CCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCC
DATQTPVLFDAEIDGKKRKIVAQASRNGYFFAIDRATGKNIVSAEYVKGNWSKGVDAKGS
CCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCC
PIPNPEKEPQLDGALVSPNQGGGTNWPPPTYNPDTGLFYVNASRAFSVYYIYDPSDKPEG
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCC
WGGNDRGGWGEAMIQAIDPKTGKVKWTHKWEDGSRGGLLSTAGKLLFGGDGSGNLVALDP
CCCCCCCCHHHHHHEEECCCCCEEEEEEECCCCCCCCCHHCCCEEEECCCCCCCEEEECC
ANGNPLWHANLGNSVTNGPITYELDGTQYLVVGAGDTLYGFAMLR
CCCCEEEEECCCCCCCCCCEEEEECCCEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MRVLATFLLACGAVSAQGGLNPAKLGAPPTDTWPTYNGDYTGRRYSTLSKINQGNINSLS
CHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEE
LAWVYRANGALGSGPPGGRISSTPVQVNGVLYFTMPDHAWAVDARTGREVWHFRWTSHGG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCEEEEEEECCCCC
EHIGNRGAGVYGNWLYFLTPDCNMVSLNLKDGSERWRTSVCDLDQYYFGSMAPLVVKNHI
HHCCCCCCCEEECEEEEECCCCCEEEEECCCCHHHHHHHHHCCHHHHHCCCCCEEEECEE
ITGVSGDDLDRPGYIEAHDPETGALQWRWYTVPQKMGDPGSETWPNEEAMKHGGGMTWLT
EECCCCCCCCCCCEEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHCCCEEEEC
PTYDPELNMIYVPTGNPQPVIAGKARPGANLFTASVVALNPDTGKMQWYFQSSPHDTHDW
CCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCC
DATQTPVLFDAEIDGKKRKIVAQASRNGYFFAIDRATGKNIVSAEYVKGNWSKGVDAKGS
CCCCCCEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCC
PIPNPEKEPQLDGALVSPNQGGGTNWPPPTYNPDTGLFYVNASRAFSVYYIYDPSDKPEG
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCC
WGGNDRGGWGEAMIQAIDPKTGKVKWTHKWEDGSRGGLLSTAGKLLFGGDGSGNLVALDP
CCCCCCCCHHHHHHEEECCCCCEEEEEEECCCCCCCCCHHCCCEEEECCCCCCCEEEECC
ANGNPLWHANLGNSVTNGPITYELDGTQYLVVGAGDTLYGFAMLR
CCCCEEEEECCCCCCCCCCEEEEECCCEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]