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The map label for this gene is 116625212

Identifier: 116625212

GI number: 116625212

Start: 7700035

End: 7701228

Strand: Direct

Name: 116625212

Synonym: Acid_6157

Alternate gene names: NA

Gene position: 7700035-7701228 (Clockwise)

Preceding gene: 116625209

Following gene: 116625213

Centisome position: 77.27

GC content: 63.74

Gene sequence:

>1194_bases
GTGGTGGCCGCCGCCGGCGCCGCACTTTGGGCCCAGGCGGGTAACGCTCCCGCCGTTTCCGATCGCGCCCGTAAGCTGCA
TCTGAGTTCGCTGGTGTTCGATGGCCACGTCCACGCCGTGGATCGCGAGTTCTATCACGGCGGGGATATCGGCGCGCGCA
AACCAGACGGCCAGTTCGATCTCGAGCGCGCCCGGGAGGGCGGCCTCGGCGCTCTGTTTTTTTCCATCTTCGTCACCGAG
GACTACTATCCGGCGCGCCTGGAGACGAAGCAGGCATTGCGCATGCTGGATTGCGCGGTGGAGCAGATCGCGCGCAATGG
CCGGACCATCGAGATCGCGCGCAATGCGGCCGATATCGAGCGGATCCGCGCCGCCGGCAAAATGGCCGCTGTATTGGATA
TAGAAGGCAGCTTCGATCTGGATGGCGACCCTGCCGTGATTCGAAGGATGCACGCGCTGGGTATGCGTTCCATCCAGCTT
TCCGCGCACAACTGGACCAGCAACTACGCGGACTCGTGCTGCTCGCAGCCGAAGTGGAAGGGGCTGAACGATCGCGGAAT
CGCCGTGATTCACGAAATGAACCGGCTCGGCATGTTGATCAACGTTTCCCATGCTTCGGACGAAGCGATCTCGCAGGCCA
TCGACGCGAGCAGTGTGCCGGTGGTCGCGACCCACCACGGTCTGCGGGCGATCAACGACATTCCACGCAACATGCCGGAT
GCGTTGATGCGGAAGCTTGCGGCGAAGGGTGGCGTGATCGGTTTCCAACTAGGCAGCGAGTTCCACAGCCGCAAGGCCTT
TGCGTGGCGGGCCGGCCAGGCGGGCAAGCCATTCTGGGACACCAGCGCGATTGTGGAACGTGGGACACGTCTGAATATCT
ATGAGATCGACCGGATCGTGGCGCCGCAATTTCCGATGGTCCCGGCCGCGATCCCGCAGGACCTGCTGGTCAGCATCGAC
GAATGGGTCGCGGTGATCGATCGCGCGATCGGAATTGTGGGCGAGGATCATGTCGCGCTAGGCAGCGATTTCGACGGCGG
CCCTCCCCTGCCCCACGGCATGCGCGATGTCCGCGACCTGCCGATGATCACCGACGCCATGCTGCGCCGCGGATACTCCG
AGGGTCGGATTCGCAAGTTCCTGGGCGGCAATCTGCTGCGCGTGTTCCGCGAGATTACCGAAGGCCACCGCTAG

Upstream 100 bases:

>100_bases
GAAGTAGGTGGTGACGATGGCGGCAATTTTGGGACGGGTTGATGTGCTCATGCACCTCCGATCGATTGCCTACGATTATA
GGACTGCAGCGGGAGTCCTG

Downstream 100 bases:

>100_bases
GTTCCCTCGTAAACTGTCAACAATCTCACTCTGTCGATATTTTAAGATTTGTTCCGGCAAATGAATCTGATATCATCCCG
CCCACGACGATTTGTAACCG

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MVAAAGAALWAQAGNAPAVSDRARKLHLSSLVFDGHVHAVDREFYHGGDIGARKPDGQFDLERAREGGLGALFFSIFVTE
DYYPARLETKQALRMLDCAVEQIARNGRTIEIARNAADIERIRAAGKMAAVLDIEGSFDLDGDPAVIRRMHALGMRSIQL
SAHNWTSNYADSCCSQPKWKGLNDRGIAVIHEMNRLGMLINVSHASDEAISQAIDASSVPVVATHHGLRAINDIPRNMPD
ALMRKLAAKGGVIGFQLGSEFHSRKAFAWRAGQAGKPFWDTSAIVERGTRLNIYEIDRIVAPQFPMVPAAIPQDLLVSID
EWVAVIDRAIGIVGEDHVALGSDFDGGPPLPHGMRDVRDLPMITDAMLRRGYSEGRIRKFLGGNLLRVFREITEGHR

Sequences:

>Translated_397_residues
MVAAAGAALWAQAGNAPAVSDRARKLHLSSLVFDGHVHAVDREFYHGGDIGARKPDGQFDLERAREGGLGALFFSIFVTE
DYYPARLETKQALRMLDCAVEQIARNGRTIEIARNAADIERIRAAGKMAAVLDIEGSFDLDGDPAVIRRMHALGMRSIQL
SAHNWTSNYADSCCSQPKWKGLNDRGIAVIHEMNRLGMLINVSHASDEAISQAIDASSVPVVATHHGLRAINDIPRNMPD
ALMRKLAAKGGVIGFQLGSEFHSRKAFAWRAGQAGKPFWDTSAIVERGTRLNIYEIDRIVAPQFPMVPAAIPQDLLVSID
EWVAVIDRAIGIVGEDHVALGSDFDGGPPLPHGMRDVRDLPMITDAMLRRGYSEGRIRKFLGGNLLRVFREITEGHR
>Mature_397_residues
MVAAAGAALWAQAGNAPAVSDRARKLHLSSLVFDGHVHAVDREFYHGGDIGARKPDGQFDLERAREGGLGALFFSIFVTE
DYYPARLETKQALRMLDCAVEQIARNGRTIEIARNAADIERIRAAGKMAAVLDIEGSFDLDGDPAVIRRMHALGMRSIQL
SAHNWTSNYADSCCSQPKWKGLNDRGIAVIHEMNRLGMLINVSHASDEAISQAIDASSVPVVATHHGLRAINDIPRNMPD
ALMRKLAAKGGVIGFQLGSEFHSRKAFAWRAGQAGKPFWDTSAIVERGTRLNIYEIDRIVAPQFPMVPAAIPQDLLVSID
EWVAVIDRAIGIVGEDHVALGSDFDGGPPLPHGMRDVRDLPMITDAMLRRGYSEGRIRKFLGGNLLRVFREITEGHR

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=384, Percent_Identity=26.8229166666667, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI193211608, Length=384, Percent_Identity=26.3020833333333, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI193211610, Length=384, Percent_Identity=26.3020833333333, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI189458885, Length=347, Percent_Identity=24.4956772334294, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4758190, Length=347, Percent_Identity=24.4956772334294, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281362638, Length=369, Percent_Identity=27.3712737127371, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281362636, Length=369, Percent_Identity=27.3712737127371, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI221475880, Length=344, Percent_Identity=25.8720930232558, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161083233, Length=376, Percent_Identity=26.5957446808511, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21356391, Length=362, Percent_Identity=21.8232044198895, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 43481; Mature: 43481

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAAAGAALWAQAGNAPAVSDRARKLHLSSLVFDGHVHAVDREFYHGGDIGARKPDGQFD
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHEECCCEEEECHHHHCCCCCCCCCCCCCCC
LERAREGGLGALFFSIFVTEDYYPARLETKQALRMLDCAVEQIARNGRTIEIARNAADIE
HHHHHCCCHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHH
RIRAAGKMAAVLDIEGSFDLDGDPAVIRRMHALGMRSIQLSAHNWTSNYADSCCSQPKWK
HHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCC
GLNDRGIAVIHEMNRLGMLINVSHASDEAISQAIDASSVPVVATHHGLRAINDIPRNMPD
CCCCCCEEEEEHHHHCCEEEEECCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCHH
ALMRKLAAKGGVIGFQLGSEFHSRKAFAWRAGQAGKPFWDTSAIVERGTRLNIYEIDRIV
HHHHHHHHCCCEEEEECCCHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCEEHHHHH
APQFPMVPAAIPQDLLVSIDEWVAVIDRAIGIVGEDHVALGSDFDGGPPLPHGMRDVRDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHC
PMITDAMLRRGYSEGRIRKFLGGNLLRVFREITEGHR
CHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVAAAGAALWAQAGNAPAVSDRARKLHLSSLVFDGHVHAVDREFYHGGDIGARKPDGQFD
CCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHEECCCEEEECHHHHCCCCCCCCCCCCCCC
LERAREGGLGALFFSIFVTEDYYPARLETKQALRMLDCAVEQIARNGRTIEIARNAADIE
HHHHHCCCHHEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHH
RIRAAGKMAAVLDIEGSFDLDGDPAVIRRMHALGMRSIQLSAHNWTSNYADSCCSQPKWK
HHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCC
GLNDRGIAVIHEMNRLGMLINVSHASDEAISQAIDASSVPVVATHHGLRAINDIPRNMPD
CCCCCCEEEEEHHHHCCEEEEECCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCHH
ALMRKLAAKGGVIGFQLGSEFHSRKAFAWRAGQAGKPFWDTSAIVERGTRLNIYEIDRIV
HHHHHHHHCCCEEEEECCCHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCEEHHHHH
APQFPMVPAAIPQDLLVSIDEWVAVIDRAIGIVGEDHVALGSDFDGGPPLPHGMRDVRDL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHC
PMITDAMLRRGYSEGRIRKFLGGNLLRVFREITEGHR
CHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]