Click here to switch to the map view.

The map label for this gene is qheDH [H]

Identifier: 116625188

GI number: 116625188

Start: 7667096

End: 7668784

Strand: Reverse

Name: qheDH [H]

Synonym: Acid_6133

Alternate gene names: 116625188

Gene position: 7668784-7667096 (Counterclockwise)

Preceding gene: 116625189

Following gene: 116625187

Centisome position: 76.95

GC content: 61.46

Gene sequence:

>1689_bases
ATGACGATCAAGAATCTCTTATTGACCGTACCGTTTTTCCTCGCGCCGGCCTTCCTGATGGCGCAGGGCAAAGGAGTCGC
CCCGGCGGAACTGCTGAAGCCATTGCGCGATTCGTGGCCAACTTATAACGGCGACTATTCCGGCCGGCGTTACAGCGCCC
TCACGCAGGTAAATCAGTCCAACGTCCAGCACCTCACGCTTGCGTGGATGACGCGGGTAACGCCGGGAGCGGGAAATGCG
GCGCCCACTGGCGGACGCGGCGGCGGTGGTTTTGGCGGCGCGTCGAACGTCATCACGGGCGGCGAAGGTCCAGGCGATAT
TGCGGTGGGAGGCGGCACTATCAAGGCGTCCGCGCTCCAGGTGGACGGCACTCTGTACTTCACGATGCCCGACAATGCCT
GGGCTGTGGATGCACGCGACGGTCGGGAACTTTGGCATTACTTCTGGAAGACAAAAGGCGGCACGCATATCGGCAATCGC
GGACTTGCCATGTGGAACAACTACCTCTACATGGAGACGCCCGACGATTACCTGGTCTCGCTCGATGCCCGCACCGGTAA
AGAGCGCTGGCACAAGACCATCGCTGACCTCGCGCAAGGCTACTTCTCCACCCCCGCGCCCATCGTGGTCGGAAATCACG
TTCTGGTCGGAACCGGCAACGATATCGATGCCCCCGGCTTTTTGCAGTCCTTCGACCCGGAGAGCGGCGAGCTGCAATGG
AAGCTCTATACGGTTCCGATGAAGGCCGGAGATCCGGGACTCGAAACGTGGGCCAGTTTGGATGCGGCCCGTCACGGCGG
CGGCCAGACGTGGATTCCCGGCGCGTACGATCCCGAAACCAAGCTCTATATTTTCGGCACCGGCAACCCGACGCCGGCGT
TCACCACCGGAACTCGCGGCGATGGCGATAACCTGTTCACCTGCGCGCTGGTCGCGGTGAATGTAGATACGGGCAAAATG
GCCTGGCACTTCTCCACCTCGCCTCACGACATGCACGACTACGACTCCGCGCAAACGCCCGTGCTGGTTGACGCGATGTT
TAACGGCAAAATGCGCAAGCTGGTCCTGACAGCCGCCAGGAACGGCTATTACTTCACGCTGGATCGTGTTACGGGCGAGC
GTCTCGTCTCTGCTAAGTACGGCCTGGATACGAACTGGGCTAAAGGCATGAATGATTCTGGCGCGCCGCAGCACGACCCC
GGGAAGGACGCCACGGTCGCAGGTTCGCTGGTTTCTCCCAACTCAGACGGCACCACCAATTGGGAGCCACCCGCCTTCTC
GCCCGACACCGGCTACTTTTACGTGGCGGAGGGCAACGCGTATTCCATCTTTTACCTGACCGATGTGGATCCGCGCGGTT
CGATGGGGCTCGGCGGCAAGGAGGAGGTCGGCGTCGGTACAGGGGGCAGTTACCTGACTGCGATCGATTATCGGACAGGC
AAAGTTGCCTGGCGGCGTCCTTATTACGGCAACGGCGGAGGAGGAGGACTGTTGACCACGGCGGGCAAACTCCTGTTCGC
AGGCGATGGGGCCGGCAATCTGGTGGCGCACGACGCGGGCACCGGCAAGCCCCTGTGGAACACGCGCATCGGCGGGATTT
CTAACGCGCCGCAGACTTTCATGCTCGATGGGCGCCAATACGTGATTGCCGCTACCGGAGATGCAATCTGGGCGTTCGTT
ATGTACTGA

Upstream 100 bases:

>100_bases
AGGTCGAAGTGCACGACCCCATGAAAGGGCATCGCGACCTGTTGGCCGTCTACACCGACAAAGATATGCACGACGTGACT
GCTTTTCTGGTGACTCTGAA

Downstream 100 bases:

>100_bases
AAGCGGTTCCATGGTCACGTTAAGCCTATCAGCCGGCGGCGCTTAACCTTCGCCGCGGAACCAAATCGTGTCATCGCACG
TCCAACAGCATGTCTCACCA

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MTIKNLLLTVPFFLAPAFLMAQGKGVAPAELLKPLRDSWPTYNGDYSGRRYSALTQVNQSNVQHLTLAWMTRVTPGAGNA
APTGGRGGGGFGGASNVITGGEGPGDIAVGGGTIKASALQVDGTLYFTMPDNAWAVDARDGRELWHYFWKTKGGTHIGNR
GLAMWNNYLYMETPDDYLVSLDARTGKERWHKTIADLAQGYFSTPAPIVVGNHVLVGTGNDIDAPGFLQSFDPESGELQW
KLYTVPMKAGDPGLETWASLDAARHGGGQTWIPGAYDPETKLYIFGTGNPTPAFTTGTRGDGDNLFTCALVAVNVDTGKM
AWHFSTSPHDMHDYDSAQTPVLVDAMFNGKMRKLVLTAARNGYYFTLDRVTGERLVSAKYGLDTNWAKGMNDSGAPQHDP
GKDATVAGSLVSPNSDGTTNWEPPAFSPDTGYFYVAEGNAYSIFYLTDVDPRGSMGLGGKEEVGVGTGGSYLTAIDYRTG
KVAWRRPYYGNGGGGGLLTTAGKLLFAGDGAGNLVAHDAGTGKPLWNTRIGGISNAPQTFMLDGRQYVIAATGDAIWAFV
MY

Sequences:

>Translated_562_residues
MTIKNLLLTVPFFLAPAFLMAQGKGVAPAELLKPLRDSWPTYNGDYSGRRYSALTQVNQSNVQHLTLAWMTRVTPGAGNA
APTGGRGGGGFGGASNVITGGEGPGDIAVGGGTIKASALQVDGTLYFTMPDNAWAVDARDGRELWHYFWKTKGGTHIGNR
GLAMWNNYLYMETPDDYLVSLDARTGKERWHKTIADLAQGYFSTPAPIVVGNHVLVGTGNDIDAPGFLQSFDPESGELQW
KLYTVPMKAGDPGLETWASLDAARHGGGQTWIPGAYDPETKLYIFGTGNPTPAFTTGTRGDGDNLFTCALVAVNVDTGKM
AWHFSTSPHDMHDYDSAQTPVLVDAMFNGKMRKLVLTAARNGYYFTLDRVTGERLVSAKYGLDTNWAKGMNDSGAPQHDP
GKDATVAGSLVSPNSDGTTNWEPPAFSPDTGYFYVAEGNAYSIFYLTDVDPRGSMGLGGKEEVGVGTGGSYLTAIDYRTG
KVAWRRPYYGNGGGGGLLTTAGKLLFAGDGAGNLVAHDAGTGKPLWNTRIGGISNAPQTFMLDGRQYVIAATGDAIWAFV
MY
>Mature_561_residues
TIKNLLLTVPFFLAPAFLMAQGKGVAPAELLKPLRDSWPTYNGDYSGRRYSALTQVNQSNVQHLTLAWMTRVTPGAGNAA
PTGGRGGGGFGGASNVITGGEGPGDIAVGGGTIKASALQVDGTLYFTMPDNAWAVDARDGRELWHYFWKTKGGTHIGNRG
LAMWNNYLYMETPDDYLVSLDARTGKERWHKTIADLAQGYFSTPAPIVVGNHVLVGTGNDIDAPGFLQSFDPESGELQWK
LYTVPMKAGDPGLETWASLDAARHGGGQTWIPGAYDPETKLYIFGTGNPTPAFTTGTRGDGDNLFTCALVAVNVDTGKMA
WHFSTSPHDMHDYDSAQTPVLVDAMFNGKMRKLVLTAARNGYYFTLDRVTGERLVSAKYGLDTNWAKGMNDSGAPQHDPG
KDATVAGSLVSPNSDGTTNWEPPAFSPDTGYFYVAEGNAYSIFYLTDVDPRGSMGLGGKEEVGVGTGGSYLTAIDYRTGK
VAWRRPYYGNGGGGGLLTTAGKLLFAGDGAGNLVAHDAGTGKPLWNTRIGGISNAPQTFMLDGRQYVIAATGDAIWAFVM
Y

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=658, Percent_Identity=24.3161094224924, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 59938; Mature: 59806

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKNLLLTVPFFLAPAFLMAQGKGVAPAELLKPLRDSWPTYNGDYSGRRYSALTQVNQS
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCC
NVQHLTLAWMTRVTPGAGNAAPTGGRGGGGFGGASNVITGGEGPGDIAVGGGTIKASALQ
CCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCEEEEEEEE
VDGTLYFTMPDNAWAVDARDGRELWHYFWKTKGGTHIGNRGLAMWNNYLYMETPDDYLVS
ECCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCCEEEE
LDARTGKERWHKTIADLAQGYFSTPAPIVVGNHVLVGTGNDIDAPGFLQSFDPESGELQW
EECCCCHHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCCCCCHHCCCCCCCCEEE
KLYTVPMKAGDPGLETWASLDAARHGGGQTWIPGAYDPETKLYIFGTGNPTPAFTTGTRG
EEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCC
DGDNLFTCALVAVNVDTGKMAWHFSTSPHDMHDYDSAQTPVLVDAMFNGKMRKLVLTAAR
CCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEC
NGYYFTLDRVTGERLVSAKYGLDTNWAKGMNDSGAPQHDPGKDATVAGSLVSPNSDGTTN
CCEEEEEECCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
WEPPAFSPDTGYFYVAEGNAYSIFYLTDVDPRGSMGLGGKEEVGVGTGGSYLTAIDYRTG
CCCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
KVAWRRPYYGNGGGGGLLTTAGKLLFAGDGAGNLVAHDAGTGKPLWNTRIGGISNAPQTF
CEEEECCCCCCCCCCCHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
MLDGRQYVIAATGDAIWAFVMY
EECCCEEEEEECCCEEEEEEEC
>Mature Secondary Structure 
TIKNLLLTVPFFLAPAFLMAQGKGVAPAELLKPLRDSWPTYNGDYSGRRYSALTQVNQS
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCC
NVQHLTLAWMTRVTPGAGNAAPTGGRGGGGFGGASNVITGGEGPGDIAVGGGTIKASALQ
CCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCEEEEEEEE
VDGTLYFTMPDNAWAVDARDGRELWHYFWKTKGGTHIGNRGLAMWNNYLYMETPDDYLVS
ECCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEECCCCEEEE
LDARTGKERWHKTIADLAQGYFSTPAPIVVGNHVLVGTGNDIDAPGFLQSFDPESGELQW
EECCCCHHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCCCCCCCCCHHCCCCCCCCEEE
KLYTVPMKAGDPGLETWASLDAARHGGGQTWIPGAYDPETKLYIFGTGNPTPAFTTGTRG
EEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCC
DGDNLFTCALVAVNVDTGKMAWHFSTSPHDMHDYDSAQTPVLVDAMFNGKMRKLVLTAAR
CCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEC
NGYYFTLDRVTGERLVSAKYGLDTNWAKGMNDSGAPQHDPGKDATVAGSLVSPNSDGTTN
CCEEEEEECCCCCEEEEEECCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
WEPPAFSPDTGYFYVAEGNAYSIFYLTDVDPRGSMGLGGKEEVGVGTGGSYLTAIDYRTG
CCCCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
KVAWRRPYYGNGGGGGLLTTAGKLLFAGDGAGNLVAHDAGTGKPLWNTRIGGISNAPQTF
CEEEECCCCCCCCCCCHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
MLDGRQYVIAATGDAIWAFVMY
EECCCEEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]