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The map label for this gene is quiP [H]

Identifier: 116625049

GI number: 116625049

Start: 7500661

End: 7502856

Strand: Direct

Name: quiP [H]

Synonym: Acid_5979

Alternate gene names: 116625049

Gene position: 7500661-7502856 (Clockwise)

Preceding gene: 116625044

Following gene: 116625053

Centisome position: 75.27

GC content: 65.94

Gene sequence:

>2196_bases
ATGAAGCGCGTATGCAGCGTACTCTTCCTCTGCTCGGGCCTGCTCTGCGCAGCCCCGATCCGCACCCCTGGACTGCGGAA
GCCCGTCGAAATCCTGCGGGATCGATGGGGCGTGCCGCACATTTACGCCGCCACCGTTCACGACCTTTTCTTCGCACAGG
GCTACATCACCGCCACCGATCGCCTTTTCCAGATCGACCTGTGGCGGCGGGTCGGGTCGGGCAAACTCGCCGAGGTCATG
GGTCCCGCGTACATCGATCGCGACCGGCTGGCGCGAGCGGTAAACTATCGCGGCGATTGGGCGGCGGAGTGGGCCGCCTA
CGGCAGCGACGCGCGCGAGATCGTCACGGCGTTCACGGAAGGCGTGAATGCGTACATCCATTCGCTGGGCGCCAACCTGC
CGCGGGAGTTCAAAATCGCGGGCTACGCGCCGGGCTTGTGGGTTCCCGAGGATTGCCTGAGCCGTGTCGCCGGCCTCACC
ATGACTGGCAACCTGACGCGCGAAGTGACCCATGCCGAGGATATACGGCGATACGGAATCGAGCGCACGCTCCAGTTCAC
TCGAATCGAACCGCACGCCGCTATGACAGTGCCCGCCGGCCTCGACCTTGCGGCGATCACGGCGGACATTCTGCGCACCT
ACCGGCAGACCGTCGGACCGGTGCGGTTGACGACCGAGCAGGGCAGCAATAACTGGGTGGTGGATGGAACGCTCACCGCG
ACGGGCCGCCCGATTCTGGCCAACGATCCGCACCGGCCGGTGCAGCTTCCCTCGCTCCGGAAAACGGTCCACCTGAACGG
GCCGGGGTGGAACGCGATCGGGTCGGGCGAGCCGGGGCTTCCCGGGATCGCGCTCGGCCACAACGATAGCGTGGCCTTCG
GTTTTACGATCGTGGGCATCGATCAGCAGGACTTGTACGTGGAGAGCGTCAACCCCTCAAACGCCGCGCAGTATCGCTAC
AGGGGCGCGTGGAAGGACTTCGAGACGCGACAACAGCAGCTGGCCCTGAAGGGCGAAGCGGCGCGGACGATTACGCTGCG
GTACACGGTGCATGGTCCGGTGATCGCGGAGGACGGCGCCGCGCATCGCGTGTATGCGCTGCGCTGGGTGGGCAGCGAAC
CGGGGACGGCCGGCTATCTGGCGGGCCTCTCGCTGGCGCGCGCCCGCGATTGGACCGAATTTCGCGCCGCGATGGCGCGC
TACCGCGTCCCTTCGGAGAACCTGGTCTACGCCGATACCAAGGGCAATATCGGCTGGCAGGTCGGCGGCCTCACGCCGAT
CCGGGACGGTTGGAATGGCCTGCTACCCGTTCCCGGGGATGAGGGCCGATACGAATGGACCGGTTTCAGGAAGCCGGAGG
AACTGCCGTTCGAGTTCAATCCGGCGCGGCACTACATCGCCACCGCGAATCACAACATCCTGCCCGAGGGGTACAAGATC
CCGATCGGCTACGACGGGTGGGCGCTGCCTTTCCGGGTCACGCGCATTCGCGAGATGCTGGCGGCGGGCAAGAAGTTCGA
TATTGCCGATTTCGTGCGCATGCAGCAGGACGTCACATCGCTGCCGGCGCAGCGCTTCCAGGCGGCGGTGCGCGGCTGGC
ATCCGGCGGAGGGGACCGCGACGGCGCGCGCCCTCGCGGAGGTATTGCAATGGCACGCGGTGCTGGCGGCAAACTCGCAC
GCCGCGCTGCTCTACGAATTGTGGATGTCGAAACTGCCGTCCGCGCTGTTTGGGGAGATGGCGGCGAAAGCCGATCTCGA
CATGCAGCTTCGCAAACTCGAGGCCGGCGTGGATCCGGCGATTCTTGAGAAGACGCTGGAGGGAGCGCTCGCCGAGGTGG
ATCGGCGCAAGGTGACGACCTGGGGCGCGCTGCACCAACTCACGCTGGCGCACCCGCTCGGTAAAGCCGAATTCCAGCTC
GGCCCCGTGCCGCGGCCCGGCGATGCCAACACGGTAAACGCCACCAGCGGAACCAACTTCCGGCAGACCAATGGCGCCTC
CTGGCGCGAGGTGCTCGACGTGGGCGATTGGGACCGGTCGGTGATGACCAACGTCCCCGGCGAATCCGGCAATCCCGGCA
GTTCGCATTATTCGGATCTGCTGGCCGATTGGGCGGCGGGGCGATATCATCCACTGCCTTTTTCGCGCAAAGCAGTCGAG
GCAGCCACCGAAGAACGCATCGAACTAATACCGTGA

Upstream 100 bases:

>100_bases
TGTGATTTTCCGGTCCAAAGTACGGCCGGCCTCCTCTTGTGTATACGATATCACCGGATGTAATGGATTCAACATTATTA
GCCCGTGTTATCTTTGGCCA

Downstream 100 bases:

>100_bases
AGTGTGGCTGCTAAGGTGTGGATCCGGATCTGATACGGCCAAAATGGGAAATTCCTACTGGAGCTTGGCTTCCAGTTCGG
CCCAGCGGGCGTAGAGCTGG

Product: penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MKRVCSVLFLCSGLLCAAPIRTPGLRKPVEILRDRWGVPHIYAATVHDLFFAQGYITATDRLFQIDLWRRVGSGKLAEVM
GPAYIDRDRLARAVNYRGDWAAEWAAYGSDAREIVTAFTEGVNAYIHSLGANLPREFKIAGYAPGLWVPEDCLSRVAGLT
MTGNLTREVTHAEDIRRYGIERTLQFTRIEPHAAMTVPAGLDLAAITADILRTYRQTVGPVRLTTEQGSNNWVVDGTLTA
TGRPILANDPHRPVQLPSLRKTVHLNGPGWNAIGSGEPGLPGIALGHNDSVAFGFTIVGIDQQDLYVESVNPSNAAQYRY
RGAWKDFETRQQQLALKGEAARTITLRYTVHGPVIAEDGAAHRVYALRWVGSEPGTAGYLAGLSLARARDWTEFRAAMAR
YRVPSENLVYADTKGNIGWQVGGLTPIRDGWNGLLPVPGDEGRYEWTGFRKPEELPFEFNPARHYIATANHNILPEGYKI
PIGYDGWALPFRVTRIREMLAAGKKFDIADFVRMQQDVTSLPAQRFQAAVRGWHPAEGTATARALAEVLQWHAVLAANSH
AALLYELWMSKLPSALFGEMAAKADLDMQLRKLEAGVDPAILEKTLEGALAEVDRRKVTTWGALHQLTLAHPLGKAEFQL
GPVPRPGDANTVNATSGTNFRQTNGASWREVLDVGDWDRSVMTNVPGESGNPGSSHYSDLLADWAAGRYHPLPFSRKAVE
AATEERIELIP

Sequences:

>Translated_731_residues
MKRVCSVLFLCSGLLCAAPIRTPGLRKPVEILRDRWGVPHIYAATVHDLFFAQGYITATDRLFQIDLWRRVGSGKLAEVM
GPAYIDRDRLARAVNYRGDWAAEWAAYGSDAREIVTAFTEGVNAYIHSLGANLPREFKIAGYAPGLWVPEDCLSRVAGLT
MTGNLTREVTHAEDIRRYGIERTLQFTRIEPHAAMTVPAGLDLAAITADILRTYRQTVGPVRLTTEQGSNNWVVDGTLTA
TGRPILANDPHRPVQLPSLRKTVHLNGPGWNAIGSGEPGLPGIALGHNDSVAFGFTIVGIDQQDLYVESVNPSNAAQYRY
RGAWKDFETRQQQLALKGEAARTITLRYTVHGPVIAEDGAAHRVYALRWVGSEPGTAGYLAGLSLARARDWTEFRAAMAR
YRVPSENLVYADTKGNIGWQVGGLTPIRDGWNGLLPVPGDEGRYEWTGFRKPEELPFEFNPARHYIATANHNILPEGYKI
PIGYDGWALPFRVTRIREMLAAGKKFDIADFVRMQQDVTSLPAQRFQAAVRGWHPAEGTATARALAEVLQWHAVLAANSH
AALLYELWMSKLPSALFGEMAAKADLDMQLRKLEAGVDPAILEKTLEGALAEVDRRKVTTWGALHQLTLAHPLGKAEFQL
GPVPRPGDANTVNATSGTNFRQTNGASWREVLDVGDWDRSVMTNVPGESGNPGSSHYSDLLADWAAGRYHPLPFSRKAVE
AATEERIELIP
>Mature_731_residues
MKRVCSVLFLCSGLLCAAPIRTPGLRKPVEILRDRWGVPHIYAATVHDLFFAQGYITATDRLFQIDLWRRVGSGKLAEVM
GPAYIDRDRLARAVNYRGDWAAEWAAYGSDAREIVTAFTEGVNAYIHSLGANLPREFKIAGYAPGLWVPEDCLSRVAGLT
MTGNLTREVTHAEDIRRYGIERTLQFTRIEPHAAMTVPAGLDLAAITADILRTYRQTVGPVRLTTEQGSNNWVVDGTLTA
TGRPILANDPHRPVQLPSLRKTVHLNGPGWNAIGSGEPGLPGIALGHNDSVAFGFTIVGIDQQDLYVESVNPSNAAQYRY
RGAWKDFETRQQQLALKGEAARTITLRYTVHGPVIAEDGAAHRVYALRWVGSEPGTAGYLAGLSLARARDWTEFRAAMAR
YRVPSENLVYADTKGNIGWQVGGLTPIRDGWNGLLPVPGDEGRYEWTGFRKPEELPFEFNPARHYIATANHNILPEGYKI
PIGYDGWALPFRVTRIREMLAAGKKFDIADFVRMQQDVTSLPAQRFQAAVRGWHPAEGTATARALAEVLQWHAVLAANSH
AALLYELWMSKLPSALFGEMAAKADLDMQLRKLEAGVDPAILEKTLEGALAEVDRRKVTTWGALHQLTLAHPLGKAEFQL
GPVPRPGDANTVNATSGTNFRQTNGASWREVLDVGDWDRSVMTNVPGESGNPGSSHYSDLLADWAAGRYHPLPFSRKAVE
AATEERIELIP

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 80515; Mature: 80515

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVCSVLFLCSGLLCAAPIRTPGLRKPVEILRDRWGVPHIYAATVHDLFFAQGYITATD
CHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHCCEEEECC
RLFQIDLWRRVGSGKLAEVMGPAYIDRDRLARAVNYRGDWAAEWAAYGSDAREIVTAFTE
EEEEEEHHHHCCCCCHHHHHCCHHCCHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHH
GVNAYIHSLGANLPREFKIAGYAPGLWVPEDCLSRVAGLTMTGNLTREVTHAEDIRRYGI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHCH
ERTLQFTRIEPHAAMTVPAGLDLAAITADILRTYRQTVGPVRLTTEQGSNNWVVDGTLTA
HHCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEE
TGRPILANDPHRPVQLPSLRKTVHLNGPGWNAIGSGEPGLPGIALGHNDSVAFGFTIVGI
CCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
DQQDLYVESVNPSNAAQYRYRGAWKDFETRQQQLALKGEAARTITLRYTVHGPVIAEDGA
CCCCCEEEECCCCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCEEECCCC
AHRVYALRWVGSEPGTAGYLAGLSLARARDWTEFRAAMARYRVPSENLVYADTKGNIGWQ
CCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEE
VGGLTPIRDGWNGLLPVPGDEGRYEWTGFRKPEELPFEFNPARHYIATANHNILPEGYKI
ECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCCEE
PIGYDGWALPFRVTRIREMLAAGKKFDIADFVRMQQDVTSLPAQRFQAAVRGWHPAEGTA
ECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
TARALAEVLQWHAVLAANSHAALLYELWMSKLPSALFGEMAAKADLDMQLRKLEAGVDPA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCHH
ILEKTLEGALAEVDRRKVTTWGALHQLTLAHPLGKAEFQLGPVPRPGDANTVNATSGTNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEECCCCCCC
RQTNGASWREVLDVGDWDRSVMTNVPGESGNPGSSHYSDLLADWAAGRYHPLPFSRKAVE
CCCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
AATEERIELIP
HHHHHHHCCCC
>Mature Secondary Structure
MKRVCSVLFLCSGLLCAAPIRTPGLRKPVEILRDRWGVPHIYAATVHDLFFAQGYITATD
CHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHCCEEEECC
RLFQIDLWRRVGSGKLAEVMGPAYIDRDRLARAVNYRGDWAAEWAAYGSDAREIVTAFTE
EEEEEEHHHHCCCCCHHHHHCCHHCCHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHH
GVNAYIHSLGANLPREFKIAGYAPGLWVPEDCLSRVAGLTMTGNLTREVTHAEDIRRYGI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHCH
ERTLQFTRIEPHAAMTVPAGLDLAAITADILRTYRQTVGPVRLTTEQGSNNWVVDGTLTA
HHCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEE
TGRPILANDPHRPVQLPSLRKTVHLNGPGWNAIGSGEPGLPGIALGHNDSVAFGFTIVGI
CCCCEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
DQQDLYVESVNPSNAAQYRYRGAWKDFETRQQQLALKGEAARTITLRYTVHGPVIAEDGA
CCCCCEEEECCCCCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCEEECCCC
AHRVYALRWVGSEPGTAGYLAGLSLARARDWTEFRAAMARYRVPSENLVYADTKGNIGWQ
CCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEE
VGGLTPIRDGWNGLLPVPGDEGRYEWTGFRKPEELPFEFNPARHYIATANHNILPEGYKI
ECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCCEE
PIGYDGWALPFRVTRIREMLAAGKKFDIADFVRMQQDVTSLPAQRFQAAVRGWHPAEGTA
ECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
TARALAEVLQWHAVLAANSHAALLYELWMSKLPSALFGEMAAKADLDMQLRKLEAGVDPA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCHH
ILEKTLEGALAEVDRRKVTTWGALHQLTLAHPLGKAEFQLGPVPRPGDANTVNATSGTNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEECCCCCCC
RQTNGASWREVLDVGDWDRSVMTNVPGESGNPGSSHYSDLLADWAAGRYHPLPFSRKAVE
CCCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
AATEERIELIP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]