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The map label for this gene is ahpC [C]

Identifier: 116624971

GI number: 116624971

Start: 7398845

End: 7399504

Strand: Reverse

Name: ahpC [C]

Synonym: Acid_5901

Alternate gene names: 116624971

Gene position: 7399504-7398845 (Counterclockwise)

Preceding gene: 116624974

Following gene: 116624969

Centisome position: 74.25

GC content: 57.42

Gene sequence:

>660_bases
ATGTCCCTACGAATCAACTCTGAAGCACCGAACTTTACGGCCGAGACCACACAAGGGCCCATTAATTTCCACGAGTGGAT
CGGCGACGGATGGGCGATTCTGTTTTCCCATCCGAAGGATTTTACGCCGGTCTGCACCACGGAACTCGGCTATATGGCCG
GCTTGGCGCCGGAATTCGCCAAAAGAAACGTCAAGATCATCGGGTTGAGCGTAGACCCGGTAACGAATCACGGGAAATGG
GCGGCCGACATCGAAGAAACCCAGGGGCATGCAGTGACTTATCCGATGATTGGCGATCCCGAGCTCAAAGTGGCCAAGCT
TTACGACATGCTGCCCGAGGATGCCGGCACCACGTCTGAAGGCCGCACGGCGGCGAACAATGCGACGGTGCGCACGGTGT
TTGTGATCGGGCCCGATAAGAAGATCAAGCTGATGCTGATCTATCCCATGACGACGGGCCGCAACTTCGACGAAGTGCTG
CGCGTGATCGATTCGATGCAGCTCACCGCCAAGCACCAGGTGGCCACGCCGGTGAATTGGAAGCCGGGCGACGACGTGAT
CATTGTGCCCGCGGTCTCCGACGACGACGCGAAGAAGAAATACCCGGAAGGGTTTAAGACTATTAAGCCGTACCTGCGCA
CGGTAGCGCAGCCGAAGTAA

Upstream 100 bases:

>100_bases
CGACGATTCTCCCGGGGAGGGCAGGTCCATAGTGAAAACTCATTCTAATTGACGGCGATCGAGAAAGTCGGGACGCCGGA
TTTCGCGTACAATTTCAAGC

Downstream 100 bases:

>100_bases
GAACTACTGATTAGTGCGCCGGCTGAAAGCCGGCGGCAGCCAGGATTGGCTGCCCCACAACGGACGCTCCCTGACGGTCG
CGGCTCTGATTGAGGGCGAT

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSLRINSEAPNFTAETTQGPINFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLAPEFAKRNVKIIGLSVDPVTNHGKW
AADIEETQGHAVTYPMIGDPELKVAKLYDMLPEDAGTTSEGRTAANNATVRTVFVIGPDKKIKLMLIYPMTTGRNFDEVL
RVIDSMQLTAKHQVATPVNWKPGDDVIIVPAVSDDDAKKKYPEGFKTIKPYLRTVAQPK

Sequences:

>Translated_219_residues
MSLRINSEAPNFTAETTQGPINFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLAPEFAKRNVKIIGLSVDPVTNHGKW
AADIEETQGHAVTYPMIGDPELKVAKLYDMLPEDAGTTSEGRTAANNATVRTVFVIGPDKKIKLMLIYPMTTGRNFDEVL
RVIDSMQLTAKHQVATPVNWKPGDDVIIVPAVSDDDAKKKYPEGFKTIKPYLRTVAQPK
>Mature_218_residues
SLRINSEAPNFTAETTQGPINFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLAPEFAKRNVKIIGLSVDPVTNHGKWA
ADIEETQGHAVTYPMIGDPELKVAKLYDMLPEDAGTTSEGRTAANNATVRTVFVIGPDKKIKLMLIYPMTTGRNFDEVLR
VIDSMQLTAKHQVATPVNWKPGDDVIIVPAVSDDDAKKKYPEGFKTIKPYLRTVAQPK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=225, Percent_Identity=51.1111111111111, Blast_Score=221, Evalue=4e-58,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=30.5263157894737, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=30.5263157894737, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=30.5263157894737, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32189392, Length=203, Percent_Identity=28.0788177339901, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI5453549, Length=159, Percent_Identity=28.9308176100629, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI5802974, Length=153, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI32483377, Length=153, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=30.9677419354839, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=228, Percent_Identity=39.4736842105263, Blast_Score=161, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32565831, Length=161, Percent_Identity=29.8136645962733, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193204376, Length=161, Percent_Identity=29.8136645962733, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17554494, Length=164, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319407, Length=215, Percent_Identity=57.2093023255814, Blast_Score=239, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6323613, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581278, Length=223, Percent_Identity=47.9820627802691, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24652436, Length=210, Percent_Identity=48.5714285714286, Blast_Score=207, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24652434, Length=210, Percent_Identity=48.0952380952381, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI17975518, Length=210, Percent_Identity=48.0952380952381, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21357347, Length=185, Percent_Identity=31.3513513513514, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17157991, Length=174, Percent_Identity=30.4597701149425, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641739, Length=174, Percent_Identity=30.4597701149425, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17738015, Length=190, Percent_Identity=27.3684210526316, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=169, Percent_Identity=27.2189349112426, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864676, Length=169, Percent_Identity=27.2189349112426, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24185; Mature: 24054

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRINSEAPNFTAETTQGPINFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLAPEFA
CEEEECCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHH
KRNVKIIGLSVDPVTNHGKWAADIEETQGHAVTYPMIGDPELKVAKLYDMLPEDAGTTSE
HCCEEEEEEEECCCCCCCCEEECHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
GRTAANNATVRTVFVIGPDKKIKLMLIYPMTTGRNFDEVLRVIDSMQLTAKHQVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
KPGDDVIIVPAVSDDDAKKKYPEGFKTIKPYLRTVAQPK
CCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLRINSEAPNFTAETTQGPINFHEWIGDGWAILFSHPKDFTPVCTTELGYMAGLAPEFA
EEEECCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHH
KRNVKIIGLSVDPVTNHGKWAADIEETQGHAVTYPMIGDPELKVAKLYDMLPEDAGTTSE
HCCEEEEEEEECCCCCCCCEEECHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
GRTAANNATVRTVFVIGPDKKIKLMLIYPMTTGRNFDEVLRVIDSMQLTAKHQVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
KPGDDVIIVPAVSDDDAKKKYPEGFKTIKPYLRTVAQPK
CCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA