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The map label for this gene is zraS [C]

Identifier: 116624965

GI number: 116624965

Start: 7387786

End: 7389687

Strand: Reverse

Name: zraS [C]

Synonym: Acid_5895

Alternate gene names: 116624965

Gene position: 7389687-7387786 (Counterclockwise)

Preceding gene: 116624966

Following gene: 116624964

Centisome position: 74.15

GC content: 61.67

Gene sequence:

>1902_bases
GTGGTTCCGGAACCGGTTGAACAGTCCGAGGAGAAGCACAGGAAACAGGAAGTCCTGTCGGCGCAGGTTCACCTACTTCA
CGCGAACGCACGCTTAGGCGTTTGCGTCACAATCGTCGCAGCGGCGGTGCTGGGGCGCCTTCAGTGGGGATTCGTTGCGG
ATTCGGTGATCGTTCGATGGTGGGTCTACATGGCCCTGGTATCAATGGCCAGGTATGCCGCGGCCCGTCGTTTTCGCGAC
GCTTCACCGGGAGTGGAGGAGCACGGCAAGTGGTCGGCTGTGTTCTGCCTGGGGGCGGGCATGTCCGGGGCTGGTTGGGG
CGCAGCCGGGGTACTGCTCTATCCGGAGAGCAGCCTGACACATCAGGTATTCCTGTTCTTCGTCCTGGGAGGAATGATGC
TTGGCGCGGCGTCTCTGCTGGCCCCGAGGCCGGAGGCGTTTCTGGCATTTCTGATTCCAGCGGGCCTGATCCCCGCGATA
CGTCTCCTGTTTCAAGGCGATGAGACGCATGTCGCGATGGGCCTGCTGGCCGGCGTGTTTACGGTGGCGCTCCTGGTCAC
GACCGGGCGGATTCATCAGACCATCGACTCGTCGCTCAAGCTTCAGTTTGAAAACCGGGACCTGGTCGAAAGCCTGCGGG
CGGCAACGCGCCAGACGGAGGCACTCAATCAGACGTTGGAACTCAGGGTCCAGGAGCGCACGGCGGAACTAAGCCGGTCC
ACGGAACAACTCCGGAGGGAGATCGCGAACCGCGAACTGATGGAAGAGGAGCTGCTGCGTGCGCGGAAGCTGGAATCACT
GGGGGTCCTGGCGGGAGGCATCGCGCACGATTTCAATAACTTTCTAACCATCATTCGAGGGAATATCGAAGTAGCAATGG
AACGGCTGCAACCTGATGATCCGGTGCAGGAGATCGTCGCTGAAACGGCAACGGCGTGCCGGCGCGCGGAGCTGCTCGCG
TCTCAATTGCTGACGTTCGCGAAAGGCGGTGCTCCGGTCAGGCGGCTGGCTTCCGTCAAAGATATCGTGACAGATGCGGT
TCAACTGCTCCGCGCCGGCTCCTCGGTCAGCGTTGACGTTTCCATTGCCGCGGACCTTCGATTTGCCTATCTCGACGCCG
GTCAGATTGGACAGGTGATCCACAACCTCCTGCGCAATGCGCGGGAGGCGATGGGCGAGGGAGGGATTATCGAAGTCCGG
GCGGAGAACGTGGTCTGCCCGGATGCGATCGATACGGATCCGCGGGTCAGGATCGCGATTCGGGATTATGGCCGCGGCAT
TCCAGCCGACATTCGTCCGAGGATCTTTGACCCGTATTTCACGACCAAGCCTGGCGCCAGCGGCCTCGGCCTGGCGACGG
TTTATGCCATCGTTGCCAAGCACGAGGGGCACATTCTGGTGGAGTCGATGCCTGGTGTGGGGAGCGTATTCACGGTGGAC
CTGCCCGCCTCCAACGAGGTGCCCGCAGCGCCGATTCCGGCCGAGGCGAAGCCACAGAGGGGCACCGAGCGGCTTTTGGT
GATGGACGATGAAGAGGCGCTCCGAAAGGTTCTGAATACAGTTCTGACGCGGCTTGGCTACGAAGTCCGGACGGCTCGCG
ATGGAGCGGAGACGATCGTGCTTTACGAAGAGGCGATGGCGGCGGGGAGCCCTTTTGACGCAGTGCTGTTGGACCTGACG
GTGAGCGGCGGAATGGGCGGGGTGGAGACGGCCGCCAAATTGAAGGAGTTGAATCCTTCTGTAAGGCTGGTTGTTTCGAG
CGGATATTCGGCGTCGTCGGTCATGTCTGATTTTCGGAGGTACGGGTTTGATGCGGTTCTGCCGAAGCCGTGGACTTCGG
CGGCGGTGAGCGAGGTTGTTCGCAGGGTGCTCCTGACGGCTCCCGATCGGAAGGCGGATTAG

Upstream 100 bases:

>100_bases
GCCTGTCAGATAGGGGTTCCGAATCAGCCGATGGGCGATCCGAAGCTTTCATCAATCCGGGCTTTCCGACTGGAGCAAGT
GTGCTAGCGTGGGAGCCGTC

Downstream 100 bases:

>100_bases
GGGAGGAGTCTTGGAGGCGGCGATAATGTTTATGTGCGCAAGCGAATTCTCCTGCAGGTCCTTCAAGGAACGGCGGATGC
AAACATCCGATTCGAAGACC

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MVPEPVEQSEEKHRKQEVLSAQVHLLHANARLGVCVTIVAAAVLGRLQWGFVADSVIVRWWVYMALVSMARYAAARRFRD
ASPGVEEHGKWSAVFCLGAGMSGAGWGAAGVLLYPESSLTHQVFLFFVLGGMMLGAASLLAPRPEAFLAFLIPAGLIPAI
RLLFQGDETHVAMGLLAGVFTVALLVTTGRIHQTIDSSLKLQFENRDLVESLRAATRQTEALNQTLELRVQERTAELSRS
TEQLRREIANRELMEEELLRARKLESLGVLAGGIAHDFNNFLTIIRGNIEVAMERLQPDDPVQEIVAETATACRRAELLA
SQLLTFAKGGAPVRRLASVKDIVTDAVQLLRAGSSVSVDVSIAADLRFAYLDAGQIGQVIHNLLRNAREAMGEGGIIEVR
AENVVCPDAIDTDPRVRIAIRDYGRGIPADIRPRIFDPYFTTKPGASGLGLATVYAIVAKHEGHILVESMPGVGSVFTVD
LPASNEVPAAPIPAEAKPQRGTERLLVMDDEEALRKVLNTVLTRLGYEVRTARDGAETIVLYEEAMAAGSPFDAVLLDLT
VSGGMGGVETAAKLKELNPSVRLVVSSGYSASSVMSDFRRYGFDAVLPKPWTSAAVSEVVRRVLLTAPDRKAD

Sequences:

>Translated_633_residues
MVPEPVEQSEEKHRKQEVLSAQVHLLHANARLGVCVTIVAAAVLGRLQWGFVADSVIVRWWVYMALVSMARYAAARRFRD
ASPGVEEHGKWSAVFCLGAGMSGAGWGAAGVLLYPESSLTHQVFLFFVLGGMMLGAASLLAPRPEAFLAFLIPAGLIPAI
RLLFQGDETHVAMGLLAGVFTVALLVTTGRIHQTIDSSLKLQFENRDLVESLRAATRQTEALNQTLELRVQERTAELSRS
TEQLRREIANRELMEEELLRARKLESLGVLAGGIAHDFNNFLTIIRGNIEVAMERLQPDDPVQEIVAETATACRRAELLA
SQLLTFAKGGAPVRRLASVKDIVTDAVQLLRAGSSVSVDVSIAADLRFAYLDAGQIGQVIHNLLRNAREAMGEGGIIEVR
AENVVCPDAIDTDPRVRIAIRDYGRGIPADIRPRIFDPYFTTKPGASGLGLATVYAIVAKHEGHILVESMPGVGSVFTVD
LPASNEVPAAPIPAEAKPQRGTERLLVMDDEEALRKVLNTVLTRLGYEVRTARDGAETIVLYEEAMAAGSPFDAVLLDLT
VSGGMGGVETAAKLKELNPSVRLVVSSGYSASSVMSDFRRYGFDAVLPKPWTSAAVSEVVRRVLLTAPDRKAD
>Mature_633_residues
MVPEPVEQSEEKHRKQEVLSAQVHLLHANARLGVCVTIVAAAVLGRLQWGFVADSVIVRWWVYMALVSMARYAAARRFRD
ASPGVEEHGKWSAVFCLGAGMSGAGWGAAGVLLYPESSLTHQVFLFFVLGGMMLGAASLLAPRPEAFLAFLIPAGLIPAI
RLLFQGDETHVAMGLLAGVFTVALLVTTGRIHQTIDSSLKLQFENRDLVESLRAATRQTEALNQTLELRVQERTAELSRS
TEQLRREIANRELMEEELLRARKLESLGVLAGGIAHDFNNFLTIIRGNIEVAMERLQPDDPVQEIVAETATACRRAELLA
SQLLTFAKGGAPVRRLASVKDIVTDAVQLLRAGSSVSVDVSIAADLRFAYLDAGQIGQVIHNLLRNAREAMGEGGIIEVR
AENVVCPDAIDTDPRVRIAIRDYGRGIPADIRPRIFDPYFTTKPGASGLGLATVYAIVAKHEGHILVESMPGVGSVFTVD
LPASNEVPAAPIPAEAKPQRGTERLLVMDDEEALRKVLNTVLTRLGYEVRTARDGAETIVLYEEAMAAGSPFDAVLLDLT
VSGGMGGVETAAKLKELNPSVRLVVSSGYSASSVMSDFRRYGFDAVLPKPWTSAAVSEVVRRVLLTAPDRKAD

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=32.9218106995885, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788549, Length=320, Percent_Identity=28.125, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=28.8702928870293, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=28.0898876404494, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=118, Percent_Identity=39.8305084745763, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=29.535864978903, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=281, Percent_Identity=26.3345195729537, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=26.7782426778243, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68509; Mature: 68509

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPEPVEQSEEKHRKQEVLSAQVHLLHANARLGVCVTIVAAAVLGRLQWGFVADSVIVRW
CCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVYMALVSMARYAAARRFRDASPGVEEHGKWSAVFCLGAGMSGAGWGAAGVLLYPESSLT
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCEEEEECCCCHH
HQVFLFFVLGGMMLGAASLLAPRPEAFLAFLIPAGLIPAIRLLFQGDETHVAMGLLAGVF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TVALLVTTGRIHQTIDSSLKLQFENRDLVESLRAATRQTEALNQTLELRVQERTAELSRS
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEQLRREIANRELMEEELLRARKLESLGVLAGGIAHDFNNFLTIIRGNIEVAMERLQPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
PVQEIVAETATACRRAELLASQLLTFAKGGAPVRRLASVKDIVTDAVQLLRAGSSVSVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SIAADLRFAYLDAGQIGQVIHNLLRNAREAMGEGGIIEVRAENVVCPDAIDTDPRVRIAI
EEEECEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCEEEEE
RDYGRGIPADIRPRIFDPYFTTKPGASGLGLATVYAIVAKHEGHILVESMPGVGSVFTVD
EECCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
LPASNEVPAAPIPAEAKPQRGTERLLVMDDEEALRKVLNTVLTRLGYEVRTARDGAETIV
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHEECCCCCCEEE
LYEEAMAAGSPFDAVLLDLTVSGGMGGVETAAKLKELNPSVRLVVSSGYSASSVMSDFRR
EEHHHHHCCCCHHEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHH
YGFDAVLPKPWTSAAVSEVVRRVLLTAPDRKAD
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVPEPVEQSEEKHRKQEVLSAQVHLLHANARLGVCVTIVAAAVLGRLQWGFVADSVIVRW
CCCCCCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVYMALVSMARYAAARRFRDASPGVEEHGKWSAVFCLGAGMSGAGWGAAGVLLYPESSLT
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCEEEEECCCCHH
HQVFLFFVLGGMMLGAASLLAPRPEAFLAFLIPAGLIPAIRLLFQGDETHVAMGLLAGVF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TVALLVTTGRIHQTIDSSLKLQFENRDLVESLRAATRQTEALNQTLELRVQERTAELSRS
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEQLRREIANRELMEEELLRARKLESLGVLAGGIAHDFNNFLTIIRGNIEVAMERLQPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
PVQEIVAETATACRRAELLASQLLTFAKGGAPVRRLASVKDIVTDAVQLLRAGSSVSVDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
SIAADLRFAYLDAGQIGQVIHNLLRNAREAMGEGGIIEVRAENVVCPDAIDTDPRVRIAI
EEEECEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCEEEEE
RDYGRGIPADIRPRIFDPYFTTKPGASGLGLATVYAIVAKHEGHILVESMPGVGSVFTVD
EECCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
LPASNEVPAAPIPAEAKPQRGTERLLVMDDEEALRKVLNTVLTRLGYEVRTARDGAETIV
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHEECCCCCCEEE
LYEEAMAAGSPFDAVLLDLTVSGGMGGVETAAKLKELNPSVRLVVSSGYSASSVMSDFRR
EEHHHHHCCCCHHEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHH
YGFDAVLPKPWTSAAVSEVVRRVLLTAPDRKAD
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA