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The map label for this gene is ampH [H]

Identifier: 116624898

GI number: 116624898

Start: 7292958

End: 7294328

Strand: Direct

Name: ampH [H]

Synonym: Acid_5823

Alternate gene names: 116624898

Gene position: 7292958-7294328 (Clockwise)

Preceding gene: 116624897

Following gene: 116624899

Centisome position: 73.18

GC content: 59.88

Gene sequence:

>1371_bases
TTGAATCCGAATATATTCAACCCCCTTCCAGTTTCCGACGCCGACGAAATCCGCGAGATCCTCGTAAGACGTATCGATCA
TCAGAAGCAGGCGGCCGGCATTGTCGCCGGTATCATCGATCCGAGTGGCCGCCGCGTCGTCGCTTATGGCAACCTCGCCA
AGGGCGATCCTCGCACGGTCGATGGAGATACGATCTTCGAGATCGGATCGCTCACCAAGATCTTCACCTCGCTGCTATTG
GCGGACGCGGTGACCCACAAAGAGGTCGCCCTCGATGATTCAGCGGCCAAATACCTTCCCGAGACTGTCAAGATGCCTGA
GCGAAGCGGCAAGTCCATCACGCTGGCGGACCTTTCCACGCACAGCAGCGGGCTTCCGTCTCTGCCCGGCAACTTGAAGC
TGAAGGACGCGCGCAATCCTTACGCCGACTACCGCGTGGACGATTTATACGAGTTCCTGTCGGGGTACGCGCTGCCGCGC
GACCCCGGTTCGGAATTCGAATATTCAAACCTCGGCGGGGGGTTGCTCGGCCACGTTCTCGCGTGCCGCGCCGGAACGGA
TTATGAGAGCCTGATTCGAAGCCGCATCACGCAACCCCTCGGCATGCCGGACACGGGTATTACGCTCTCCGGCTCCATGA
AGGGGCGCATGGCGACTGGTCACAACGCGATGCTCGCGCCGGTGCCCAACTGGGATCTTGCCAGTCTTGCCGGCGCCGGC
GGGCTACGCTCTTCAGCCAATGACATGCTGACTTTGCTGGAAGCATTTCTCGGCTACAAGGACTCAAGTCTCGCACCTGC
CATGAAAGCCATGCTTGAAGTTCGCCGTCCTTTGGGCAAAATGGGGATCGGTTTAGGGTGGTTTATGCTCGGAGCGGCTG
CGTGGCACGACGGAGGTACGGGCGGCTTCCGAGCATTCGCCGGCTGCGATCTGAAAGCGCGGATCGGGGTGATTGTGTTA
TCCAATGCCGCCACTCCGAACGGTGTCGATGATATCGGGATTCATCTCCTGAACCCGAAGGCCCCACTTGCCGATCTCGA
AGCCCCAAAGCAGCGTGCGGAGATTCCGATTGACCCCCGGCTGTTCGATCGCTACACGGGGCGCTATGAGGTGACGCCAA
ACCTCGTCTTCGAAATCACACGCGAGGGCGACCGTCTCTTCGCACAGGCTTTCGTGCGGCTTCCTCACAATCGGTCCGGC
GAGGCGACCGCCGCGCCTAAGTTTGAACTGTTTGCCGAAGGCGAGAAGAACTTTTTCGCCAAGGTAACTGACAAACAGAT
CGTCTTCGAGATCGGCTCCGAGGACCGGGCCACAAGGCTTATTCTGCACCAAGGCGGCCGCGAACCAATGCCCGCGGGCC
GAGTATCGTGA

Upstream 100 bases:

>100_bases
CTGGTGGGAGTCTGCCGGGAGGCCCATGCATTCGAGAGTATCCCACGATTATTCGACGCGGTTGCTGCCTTCCGCCGGCT
CATGATAGCCTCTAACAGAA

Downstream 100 bases:

>100_bases
TTCCCGCTTCTACTCCTTACAACCCGCCGATGATTTGAGAAGCAGTACGACGACCGCGAGATAAATTGCGAATATCCCGA
CCGCTTGCTGACGGGTCCGT

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNPNIFNPLPVSDADEIREILVRRIDHQKQAAGIVAGIIDPSGRRVVAYGNLAKGDPRTVDGDTIFEIGSLTKIFTSLLL
ADAVTHKEVALDDSAAKYLPETVKMPERSGKSITLADLSTHSSGLPSLPGNLKLKDARNPYADYRVDDLYEFLSGYALPR
DPGSEFEYSNLGGGLLGHVLACRAGTDYESLIRSRITQPLGMPDTGITLSGSMKGRMATGHNAMLAPVPNWDLASLAGAG
GLRSSANDMLTLLEAFLGYKDSSLAPAMKAMLEVRRPLGKMGIGLGWFMLGAAAWHDGGTGGFRAFAGCDLKARIGVIVL
SNAATPNGVDDIGIHLLNPKAPLADLEAPKQRAEIPIDPRLFDRYTGRYEVTPNLVFEITREGDRLFAQAFVRLPHNRSG
EATAAPKFELFAEGEKNFFAKVTDKQIVFEIGSEDRATRLILHQGGREPMPAGRVS

Sequences:

>Translated_456_residues
MNPNIFNPLPVSDADEIREILVRRIDHQKQAAGIVAGIIDPSGRRVVAYGNLAKGDPRTVDGDTIFEIGSLTKIFTSLLL
ADAVTHKEVALDDSAAKYLPETVKMPERSGKSITLADLSTHSSGLPSLPGNLKLKDARNPYADYRVDDLYEFLSGYALPR
DPGSEFEYSNLGGGLLGHVLACRAGTDYESLIRSRITQPLGMPDTGITLSGSMKGRMATGHNAMLAPVPNWDLASLAGAG
GLRSSANDMLTLLEAFLGYKDSSLAPAMKAMLEVRRPLGKMGIGLGWFMLGAAAWHDGGTGGFRAFAGCDLKARIGVIVL
SNAATPNGVDDIGIHLLNPKAPLADLEAPKQRAEIPIDPRLFDRYTGRYEVTPNLVFEITREGDRLFAQAFVRLPHNRSG
EATAAPKFELFAEGEKNFFAKVTDKQIVFEIGSEDRATRLILHQGGREPMPAGRVS
>Mature_456_residues
MNPNIFNPLPVSDADEIREILVRRIDHQKQAAGIVAGIIDPSGRRVVAYGNLAKGDPRTVDGDTIFEIGSLTKIFTSLLL
ADAVTHKEVALDDSAAKYLPETVKMPERSGKSITLADLSTHSSGLPSLPGNLKLKDARNPYADYRVDDLYEFLSGYALPR
DPGSEFEYSNLGGGLLGHVLACRAGTDYESLIRSRITQPLGMPDTGITLSGSMKGRMATGHNAMLAPVPNWDLASLAGAG
GLRSSANDMLTLLEAFLGYKDSSLAPAMKAMLEVRRPLGKMGIGLGWFMLGAAAWHDGGTGGFRAFAGCDLKARIGVIVL
SNAATPNGVDDIGIHLLNPKAPLADLEAPKQRAEIPIDPRLFDRYTGRYEVTPNLVFEITREGDRLFAQAFVRLPHNRSG
EATAAPKFELFAEGEKNFFAKVTDKQIVFEIGSEDRATRLILHQGGREPMPAGRVS

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=281, Percent_Identity=29.1814946619217, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI239752721, Length=281, Percent_Identity=29.1814946619217, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI239741085, Length=281, Percent_Identity=29.1814946619217, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786574, Length=335, Percent_Identity=29.8507462686567, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790593, Length=374, Percent_Identity=24.8663101604278, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115533026, Length=280, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 49168; Mature: 49168

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNIFNPLPVSDADEIREILVRRIDHQKQAAGIVAGIIDPSGRRVVAYGNLAKGDPRTV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCCCC
DGDTIFEIGSLTKIFTSLLLADAVTHKEVALDDSAAKYLPETVKMPERSGKSITLADLST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCEEEEEECCC
HSSGLPSLPGNLKLKDARNPYADYRVDDLYEFLSGYALPRDPGSEFEYSNLGGGLLGHVL
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
ACRAGTDYESLIRSRITQPLGMPDTGITLSGSMKGRMATGHNAMLAPVPNWDLASLAGAG
HHCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCEECCCCEEEECCCCCCHHHHHCCC
GLRSSANDMLTLLEAFLGYKDSSLAPAMKAMLEVRRPLGKMGIGLGWFMLGAAAWHDGGT
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
GGFRAFAGCDLKARIGVIVLSNAATPNGVDDIGIHLLNPKAPLADLEAPKQRAEIPIDPR
CCCHHHCCCCCEEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCCCCHH
LFDRYTGRYEVTPNLVFEITREGDRLFAQAFVRLPHNRSGEATAAPKFELFAEGEKNFFA
HHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEE
KVTDKQIVFEIGSEDRATRLILHQGGREPMPAGRVS
EECCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNPNIFNPLPVSDADEIREILVRRIDHQKQAAGIVAGIIDPSGRRVVAYGNLAKGDPRTV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCCCC
DGDTIFEIGSLTKIFTSLLLADAVTHKEVALDDSAAKYLPETVKMPERSGKSITLADLST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCCCCCEEEEEECCC
HSSGLPSLPGNLKLKDARNPYADYRVDDLYEFLSGYALPRDPGSEFEYSNLGGGLLGHVL
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
ACRAGTDYESLIRSRITQPLGMPDTGITLSGSMKGRMATGHNAMLAPVPNWDLASLAGAG
HHCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCEECCCCEEEECCCCCCHHHHHCCC
GLRSSANDMLTLLEAFLGYKDSSLAPAMKAMLEVRRPLGKMGIGLGWFMLGAAAWHDGGT
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
GGFRAFAGCDLKARIGVIVLSNAATPNGVDDIGIHLLNPKAPLADLEAPKQRAEIPIDPR
CCCHHHCCCCCEEEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCCCCHH
LFDRYTGRYEVTPNLVFEITREGDRLFAQAFVRLPHNRSGEATAAPKFELFAEGEKNFFA
HHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEE
KVTDKQIVFEIGSEDRATRLILHQGGREPMPAGRVS
EECCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]