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The map label for this gene is tap [H]

Identifier: 116624818

GI number: 116624818

Start: 7190816

End: 7192219

Strand: Direct

Name: tap [H]

Synonym: Acid_5742

Alternate gene names: 116624818

Gene position: 7190816-7192219 (Clockwise)

Preceding gene: 116624817

Following gene: 116624825

Centisome position: 72.16

GC content: 61.04

Gene sequence:

>1404_bases
ATGCGTGTCAGGCAAACTACCATCGGGCGGCAATTCACCAGTATGGTGCTTGCCTTTTCAGTCGCCATGCCAGCGGCTAT
TTTCGGCTTGTCGTACGTGCTGACGGAGAATGGCGCGGCCGTTCGGCAGCTTATGGAAGAAGGCAACCGCCAAAGCGATG
CGCTGTTCGCATTGATCGGCTCGGTCGCGGAGGTGCAAGGCAACGCGCAGCGGCTGGTGCGTGAGCGCGACGCCGACGAG
CTGGAAAAACTGGTGCAGCGCACACCGCAATTGATCCAGAACGCTCTCGACAAGATCCAGGCGGCGGGTGTCGCCGAAAC
CGAGACTGCGGCCGCGTTCCGGGCCGTGCGTGAAGCCAATCAGAAGAGCCTGAATCTGGTATTGCACGGAGAACAGGCAC
AGGCGCAGACCGTGATCCTGGCCGAATCGAATCCCCAGTTCGAGCGGCTGCTGAACGAGTTGGGCAAACTTCAGCAGTTC
CAAAGCCAACGCGAAACTTCCGTTGCCGCGGAGCGCGAAGCCAAAGGGAAACGCGCGCAGTTCGCGATTCTGACGCTGGT
AGCTCTGGTGGTGTTCGCGTTGGCGGTCTGGTCGATTGTGATGGCGCGCCGAATTAACCTCGGCTTGCGCGCGGCGGTAA
CCGATTTGAGAGCCGCTTCCGGAAGCACCGCGGCCGTAGCGTCGCAGATGTCGCGCGGTTCGCAATCACTGGCGCGCGAC
GCCTCGGCGCAGGCCGCATCACTGGAAGAAACATCGGCCTCGAGTGAACATATCAGCGCCATGACGCACAAGAACGAAGA
GAATTCGCGATTGGCTGCGGCGCGCATGAAGAACGCGGGCCAGTTGGTGTCGGATGCCAACAGCCGGCTCGGCCAGATGG
TCACCGCGATGGGTGAGATCCAGGCGTCCAGCGACAAAGTCTCTAAAATCATCCGTACCATCGACGAGATCGCATTTCAA
ACCAATATCCTGGCACTCAACGCGGCCGTCGAAGCCGCGCGAGCCGGAGAATCCGGCATGGGGTTCGCGGTGGTGGCGGA
CGAAGTCCGGAATCTCGCTCAACGCTCTGCCGAAGCCGCGCGCGACACGACCGCGTTGATCGAGGAATCCATCGTGAAAT
CGCGCGACGGGAGGAGCAAGCTCGATCAGATTGTCGATTCCATCGTTTCCATCACCAAAAGTTCAGCGGGAGTGGAATCG
CTGATGGAAGAGATCCGCCAGGGCAGCGAACAACAGGCGCGCGGAATCGAGCAGGTCGGTCAAGCCTTGAACCGGATGCA
GGAGGTGACGCAGAATACCGCGGCCGGCGCCGAGCAAAGTGCCGCCGCCGGACAGGAGCTCACTGCACAATCGGAATCCT
TGAAGACCACCGTACTTAGACTGGCGGCCATGGTGGGCGCCTAG

Upstream 100 bases:

>100_bases
TTCCGGTGCTCGATGGCGCCAAACCAATCGGCTCGATCGTCTTCGGTGTCAGCATTGCGAAGCTGAAATAGAACAAGTGG
CAGTAGATCGGAGATCGGGT

Downstream 100 bases:

>100_bases
CGGTCAGGCCTCGGCGGGCGCCGGCGCCAGATGCAGGGCCTCGAGCAGCCCCTTCCATTTGCGGAGCACCAGTTCCATCA
GGTTCAACAACAGCGCCAAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-IV; Dipeptide chemoreceptor protein [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MRVRQTTIGRQFTSMVLAFSVAMPAAIFGLSYVLTENGAAVRQLMEEGNRQSDALFALIGSVAEVQGNAQRLVRERDADE
LEKLVQRTPQLIQNALDKIQAAGVAETETAAAFRAVREANQKSLNLVLHGEQAQAQTVILAESNPQFERLLNELGKLQQF
QSQRETSVAAEREAKGKRAQFAILTLVALVVFALAVWSIVMARRINLGLRAAVTDLRAASGSTAAVASQMSRGSQSLARD
ASAQAASLEETSASSEHISAMTHKNEENSRLAAARMKNAGQLVSDANSRLGQMVTAMGEIQASSDKVSKIIRTIDEIAFQ
TNILALNAAVEAARAGESGMGFAVVADEVRNLAQRSAEAARDTTALIEESIVKSRDGRSKLDQIVDSIVSITKSSAGVES
LMEEIRQGSEQQARGIEQVGQALNRMQEVTQNTAAGAEQSAAAGQELTAQSESLKTTVLRLAAMVGA

Sequences:

>Translated_467_residues
MRVRQTTIGRQFTSMVLAFSVAMPAAIFGLSYVLTENGAAVRQLMEEGNRQSDALFALIGSVAEVQGNAQRLVRERDADE
LEKLVQRTPQLIQNALDKIQAAGVAETETAAAFRAVREANQKSLNLVLHGEQAQAQTVILAESNPQFERLLNELGKLQQF
QSQRETSVAAEREAKGKRAQFAILTLVALVVFALAVWSIVMARRINLGLRAAVTDLRAASGSTAAVASQMSRGSQSLARD
ASAQAASLEETSASSEHISAMTHKNEENSRLAAARMKNAGQLVSDANSRLGQMVTAMGEIQASSDKVSKIIRTIDEIAFQ
TNILALNAAVEAARAGESGMGFAVVADEVRNLAQRSAEAARDTTALIEESIVKSRDGRSKLDQIVDSIVSITKSSAGVES
LMEEIRQGSEQQARGIEQVGQALNRMQEVTQNTAAGAEQSAAAGQELTAQSESLKTTVLRLAAMVGA
>Mature_467_residues
MRVRQTTIGRQFTSMVLAFSVAMPAAIFGLSYVLTENGAAVRQLMEEGNRQSDALFALIGSVAEVQGNAQRLVRERDADE
LEKLVQRTPQLIQNALDKIQAAGVAETETAAAFRAVREANQKSLNLVLHGEQAQAQTVILAESNPQFERLLNELGKLQQF
QSQRETSVAAEREAKGKRAQFAILTLVALVVFALAVWSIVMARRINLGLRAAVTDLRAASGSTAAVASQMSRGSQSLARD
ASAQAASLEETSASSEHISAMTHKNEENSRLAAARMKNAGQLVSDANSRLGQMVTAMGEIQASSDKVSKIIRTIDEIAFQ
TNILALNAAVEAARAGESGMGFAVVADEVRNLAQRSAEAARDTTALIEESIVKSRDGRSKLDQIVDSIVSITKSSAGVES
LMEEIRQGSEQQARGIEQVGQALNRMQEVTQNTAAGAEQSAAAGQELTAQSESLKTTVLRLAAMVGA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=250, Percent_Identity=44, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI2367378, Length=219, Percent_Identity=45.662100456621, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787690, Length=236, Percent_Identity=42.7966101694915, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1788195, Length=227, Percent_Identity=42.7312775330396, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1789453, Length=149, Percent_Identity=42.2818791946309, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 49821; Mature: 49821

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRQTTIGRQFTSMVLAFSVAMPAAIFGLSYVLTENGAAVRQLMEEGNRQSDALFALIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
SVAEVQGNAQRLVRERDADELEKLVQRTPQLIQNALDKIQAAGVAETETAAAFRAVREAN
HHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
QKSLNLVLHGEQAQAQTVILAESNPQFERLLNELGKLQQFQSQRETSVAAEREAKGKRAQ
CCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FAILTLVALVVFALAVWSIVMARRINLGLRAAVTDLRAASGSTAAVASQMSRGSQSLARD
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ASAQAASLEETSASSEHISAMTHKNEENSRLAAARMKNAGQLVSDANSRLGQMVTAMGEI
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASSDKVSKIIRTIDEIAFQTNILALNAAVEAARAGESGMGFAVVADEVRNLAQRSAEAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RDTTALIEESIVKSRDGRSKLDQIVDSIVSITKSSAGVESLMEEIRQGSEQQARGIEQVG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
QALNRMQEVTQNTAAGAEQSAAAGQELTAQSESLKTTVLRLAAMVGA
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVRQTTIGRQFTSMVLAFSVAMPAAIFGLSYVLTENGAAVRQLMEEGNRQSDALFALIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
SVAEVQGNAQRLVRERDADELEKLVQRTPQLIQNALDKIQAAGVAETETAAAFRAVREAN
HHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
QKSLNLVLHGEQAQAQTVILAESNPQFERLLNELGKLQQFQSQRETSVAAEREAKGKRAQ
CCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
FAILTLVALVVFALAVWSIVMARRINLGLRAAVTDLRAASGSTAAVASQMSRGSQSLARD
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ASAQAASLEETSASSEHISAMTHKNEENSRLAAARMKNAGQLVSDANSRLGQMVTAMGEI
HHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASSDKVSKIIRTIDEIAFQTNILALNAAVEAARAGESGMGFAVVADEVRNLAQRSAEAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
RDTTALIEESIVKSRDGRSKLDQIVDSIVSITKSSAGVESLMEEIRQGSEQQARGIEQVG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHH
QALNRMQEVTQNTAAGAEQSAAAGQELTAQSESLKTTVLRLAAMVGA
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6305515; 9097040; 9278503 [H]