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The map label for this gene is nuoC [H]

Identifier: 116624759

GI number: 116624759

Start: 7120624

End: 7121130

Strand: Direct

Name: nuoC [H]

Synonym: Acid_5683

Alternate gene names: 116624759

Gene position: 7120624-7121130 (Clockwise)

Preceding gene: 116624753

Following gene: 116624760

Centisome position: 71.45

GC content: 58.97

Gene sequence:

>507_bases
ATGGCTGCCACACCCTGGGATAGCGACCTCGCCCGTGAGCTCAAGGAGAGGTTTGGCGAAGGAATCAGCGAGACTTCCAC
CTATCTCGGACAGAATTTCCTGGTCGCCCGCCCGGATTCGGTGATTCCGATCCTGGAATACCTGAAGCTCGAAGCCGACT
TCGATTATCTGGTGGACGTGACGGCGGTCGATTGGCCCAAACGCGCCGAGCGCTTCGACCTCGTCTACATCTTGTATAGT
TTCTCGCGCAACGAGCGCGTGCGGGTCAAGGCATTCATCGCCGACGGCTACAAGCCGGAGACCGCCGTGGGGGTTCACCT
GACCGCCAACTGGCTGGAGCGCGAAGTCTTCGACATGTTTGGAATCGAATTCGCCGGTCATCCGGACATGCGCCGGATTC
TGATGCCCGAGGAATGGCAGGGCTATCCCCTGCGCAAGGATTACGGAATACTCCAGCAGGATGCGCGCTGGGTGCAGGAA
AACCTGGAAATTGAAAGCGGCCAGTGA

Upstream 100 bases:

>100_bases
CGCGGGACAACCGGTAAAACCAGCCGCTGATGCCGCGAAAGCGGCTCCTCCGAAGCCAGCCGCGGCAGCGGGAGCAGCAC
CCCCGAAGCCGCCCGCGACC

Downstream 100 bases:

>100_bases
CGACCGTATGCCGGACTCTACCTTTCTAGACTCCACCGAATTAGTTCTCAACATGGGCCCGCAGCACCCCTCCACGCACG
GGGTGCTCCGCGTCATCCTC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MAATPWDSDLARELKERFGEGISETSTYLGQNFLVARPDSVIPILEYLKLEADFDYLVDVTAVDWPKRAERFDLVYILYS
FSRNERVRVKAFIADGYKPETAVGVHLTANWLEREVFDMFGIEFAGHPDMRRILMPEEWQGYPLRKDYGILQQDARWVQE
NLEIESGQ

Sequences:

>Translated_168_residues
MAATPWDSDLARELKERFGEGISETSTYLGQNFLVARPDSVIPILEYLKLEADFDYLVDVTAVDWPKRAERFDLVYILYS
FSRNERVRVKAFIADGYKPETAVGVHLTANWLEREVFDMFGIEFAGHPDMRRILMPEEWQGYPLRKDYGILQQDARWVQE
NLEIESGQ
>Mature_167_residues
AATPWDSDLARELKERFGEGISETSTYLGQNFLVARPDSVIPILEYLKLEADFDYLVDVTAVDWPKRAERFDLVYILYSF
SRNERVRVKAFIADGYKPETAVGVHLTANWLEREVFDMFGIEFAGHPDMRRILMPEEWQGYPLRKDYGILQQDARWVQEN
LEIESGQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=154, Percent_Identity=42.2077922077922, Blast_Score=117, Evalue=5e-27,
Organism=Escherichia coli, GI145693162, Length=153, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=117, Percent_Identity=41.8803418803419, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=119, Percent_Identity=41.1764705882353, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24656494, Length=146, Percent_Identity=38.3561643835616, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19600; Mature: 19469

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATPWDSDLARELKERFGEGISETSTYLGQNFLVARPDSVIPILEYLKLEADFDYLVDV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEE
TAVDWPKRAERFDLVYILYSFSRNERVRVKAFIADGYKPETAVGVHLTANWLEREVFDMF
EECCCCCCHHHHEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHH
GIEFAGHPDMRRILMPEEWQGYPLRKDYGILQQDARWVQENLEIESGQ
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AATPWDSDLARELKERFGEGISETSTYLGQNFLVARPDSVIPILEYLKLEADFDYLVDV
CCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCEEEEE
TAVDWPKRAERFDLVYILYSFSRNERVRVKAFIADGYKPETAVGVHLTANWLEREVFDMF
EECCCCCCHHHHEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHH
GIEFAGHPDMRRILMPEEWQGYPLRKDYGILQQDARWVQENLEIESGQ
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA