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The map label for this gene is rlmH

Identifier: 116624738

GI number: 116624738

Start: 7096075

End: 7096494

Strand: Reverse

Name: rlmH

Synonym: Acid_5662

Alternate gene names: 116624738

Gene position: 7096494-7096075 (Counterclockwise)

Preceding gene: 116624739

Following gene: 116624737

Centisome position: 71.21

GC content: 64.76

Gene sequence:

>420_bases
GTGAAGATCTACCTCTACTTCATCGGCAAGCCGAAGGACCCGCATGCCAACGCCATCGCCGAGGATTTCCTGGCCCGCGC
CGGACGCTACTCCCCGTGCGAAATGCGCGAGATCAGACCCGAACGCATCGACCTCTGGACCAAACACCCCACTGCCCGCA
AGATTTTCCTGGACCCCGCCGGCAAGCCGATGGACTCCGCCGCGTTCGCGGCCATGATCTCCAAAGGCGAAATGGAGGGC
CGCGACCTGGTCTTCCTCATCGGCGGCCACGATGGCCTGCCTCCCGCGTGGCGCGCGCGCGCCGACCTTCTGGTCTCCCT
TTCCGCGATGACTTTCCCTCACGAGCTCGCGCGCGCCATGCTCGCCGAACAGATCTACCGCGGCTTCTGCACGCTGCGCA
ACCACCCTTACATCCGCTAA

Upstream 100 bases:

>100_bases
ACGGGGACCTGGTGATCCACATTTTCACGCCGAAATCGCGCGACTACTACGATCTGGAGCGCCTCTGGCGCGGCGCGAAG
GCCGTACCCATCCCGGCCGA

Downstream 100 bases:

>100_bases
GTGCTGCAACTTAACATTGCGCTGCCATCCCCTCACGGGTTAACGTAAAGTTTCCATGTCTTGGTTCAAGCGGGACAAAG
GGGACGACGACAAACTCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKIYLYFIGKPKDPHANAIAEDFLARAGRYSPCEMREIRPERIDLWTKHPTARKIFLDPAGKPMDSAAFAAMISKGEMEG
RDLVFLIGGHDGLPPAWRARADLLVSLSAMTFPHELARAMLAEQIYRGFCTLRNHPYIR

Sequences:

>Translated_139_residues
MKIYLYFIGKPKDPHANAIAEDFLARAGRYSPCEMREIRPERIDLWTKHPTARKIFLDPAGKPMDSAAFAAMISKGEMEG
RDLVFLIGGHDGLPPAWRARADLLVSLSAMTFPHELARAMLAEQIYRGFCTLRNHPYIR
>Mature_139_residues
MKIYLYFIGKPKDPHANAIAEDFLARAGRYSPCEMREIRPERIDLWTKHPTARKIFLDPAGKPMDSAAFAAMISKGEMEG
RDLVFLIGGHDGLPPAWRARADLLVSLSAMTFPHELARAMLAEQIYRGFCTLRNHPYIR

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=87, Percent_Identity=45.9770114942529, Blast_Score=83, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_SOLUE (Q01UR1)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826894.1
- ProteinModelPortal:   Q01UR1
- SMR:   Q01UR1
- STRING:   Q01UR1
- GeneID:   4426107
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5662
- NMPDR:   fig|234267.9.peg.5389
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   PHANAIA
- PhylomeDB:   Q01UR1
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 15787; Mature: 15787

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYLYFIGKPKDPHANAIAEDFLARAGRYSPCEMREIRPERIDLWTKHPTARKIFLDPA
CEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEECCCCCCEEEEECCC
GKPMDSAAFAAMISKGEMEGRDLVFLIGGHDGLPPAWRARADLLVSLSAMTFPHELARAM
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LAEQIYRGFCTLRNHPYIR
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIYLYFIGKPKDPHANAIAEDFLARAGRYSPCEMREIRPERIDLWTKHPTARKIFLDPA
CEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEECCCCCCEEEEECCC
GKPMDSAAFAAMISKGEMEGRDLVFLIGGHDGLPPAWRARADLLVSLSAMTFPHELARAM
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
LAEQIYRGFCTLRNHPYIR
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA