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The map label for this gene is queF [H]

Identifier: 116624695

GI number: 116624695

Start: 7044541

End: 7044951

Strand: Direct

Name: queF [H]

Synonym: Acid_5619

Alternate gene names: 116624695

Gene position: 7044541-7044951 (Clockwise)

Preceding gene: 116624694

Following gene: 116624696

Centisome position: 70.69

GC content: 59.61

Gene sequence:

>411_bases
ATGAAACGCGGATATACCGATGACCACGCGCGCGGCGGAATCGACGCCCCGCTTCCCGAAATCGAAACCTGGCCCAACCA
GTACGCGGATTACGAAATTGAAATCATCAATCCGGAATTCACCAGCGTATGCCCGAAGACGGGCTTGCCGGATTTCGGTA
AGGTGGTGCTGCGCTACGTGCCCGACAAGCTCTGTCTGGAGCTGAAGAGCTACAAGATGTACATGCTGGCCTATCGCGAC
CTGGGGATCTTTCAGGAGAACGTGGTCAACCGCATCCTGCAAGATGTGGTGAAGGCGGCCAAGCCGGTGAGCGCGACGGT
GATCGGAGACTTTACGCCGCGCGGTGGCTTGGGAACCCTGGTGACGGCGAGTTGGAGCCGCGCGCGGAGGAAGCCTCGTG
GAAAGCGCTGA

Upstream 100 bases:

>100_bases
CGGCGGTGGCGACGAAGGTGAGCGATCGCGGCACCGGCCAGGCGGTGGGCGTGGTGGCCGATGTCGGCCTGTTCCTGGAT
TTACTTTCGAAGGCTCTCGC

Downstream 100 bases:

>100_bases
ACTGATCGCGATTCTGCACGAGGTGCGCGACCGCGTGCGCGGCCGCAATCCGGAGACGGCCGCGGGCGGGGTCCCGGTGG
CGCTGCCGGACCTGATGCCG

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MKRGYTDDHARGGIDAPLPEIETWPNQYADYEIEIINPEFTSVCPKTGLPDFGKVVLRYVPDKLCLELKSYKMYMLAYRD
LGIFQENVVNRILQDVVKAAKPVSATVIGDFTPRGGLGTLVTASWSRARRKPRGKR

Sequences:

>Translated_136_residues
MKRGYTDDHARGGIDAPLPEIETWPNQYADYEIEIINPEFTSVCPKTGLPDFGKVVLRYVPDKLCLELKSYKMYMLAYRD
LGIFQENVVNRILQDVVKAAKPVSATVIGDFTPRGGLGTLVTASWSRARRKPRGKR
>Mature_136_residues
MKRGYTDDHARGGIDAPLPEIETWPNQYADYEIEIINPEFTSVCPKTGLPDFGKVVLRYVPDKLCLELKSYKMYMLAYRD
LGIFQENVVNRILQDVVKAAKPVSATVIGDFTPRGGLGTLVTASWSRARRKPRGKR

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 15362; Mature: 15362

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGYTDDHARGGIDAPLPEIETWPNQYADYEIEIINPEFTSVCPKTGLPDFGKVVLRYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCHHHHHHHHHC
PDKLCLELKSYKMYMLAYRDLGIFQENVVNRILQDVVKAAKPVSATVIGDFTPRGGLGTL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHH
VTASWSRARRKPRGKR
HECCHHHHHCCCCCCC
>Mature Secondary Structure
MKRGYTDDHARGGIDAPLPEIETWPNQYADYEIEIINPEFTSVCPKTGLPDFGKVVLRYV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCHHHHHHHHHC
PDKLCLELKSYKMYMLAYRDLGIFQENVVNRILQDVVKAAKPVSATVIGDFTPRGGLGTL
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHH
VTASWSRARRKPRGKR
HECCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA