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The map label for this gene is yfgC [H]

Identifier: 116624652

GI number: 116624652

Start: 6987403

End: 6988344

Strand: Direct

Name: yfgC [H]

Synonym: Acid_5576

Alternate gene names: 116624652

Gene position: 6987403-6988344 (Clockwise)

Preceding gene: 116624647

Following gene: 116624655

Centisome position: 70.11

GC content: 62.42

Gene sequence:

>942_bases
ATGTTGCTTCGCAACTGCGCCGTTGGCCTTCTTGCAATTGCCCTTGCCACGCCCGCCCCGGCCGCCCGGCGGCCCGGAGA
TCCGCTCAAACCCGGCTTTAACCTCTTCACCAAAGAAGACGACATCTCCGTCGGTAAAGAGAACGCCAGGCAAGTGCTCG
CTCAATACGACGTAGTCAAGAATCAGTTCCTCCAGGATTACGTCAATCGCATCGGCAAGAAGCTCGCCGCGGCCCCCGAA
GCGGAGAAGAGCGGCTTTCAGTTCACCTTCACCGTCCTCAATGTCGATGAGATCAACGCTTTCGCCCTCCCCGGCGGCCC
CATGTTCATCTATACCGGGCTCCTCAAAGCCATCGACAACGAGGCCCAGCTCGCCGGCGTCATGGGCCACGAGATGTCCC
ACGTGATTCTGCGCCAGGGCACTCACGAAGCCACCAAAGCCAACGGCGTCCAAATCCTCGCCGGAGGTCTCGCGACCTTG
CTCGGCGGCGGCAAACTCGTCCAGGCAGGCCTCGGCCTCACCGCCAATTCCTTCGTCCTCAAATTCTCTCGCGATGCCGA
AAGCGAAGCCGACGCGCTAGGCTCCCACCTGATGGCCGAATCCGGCTACGACCCGGTCCAGATGGCGAAGTTCTTCGAGA
AGCTTGCAGCCGGGGGCGAACGCATGCCGCAAATTCTCTCCGACCATCCCAATCCCGGCAATCGCGAGGCTGCCATTGCC
GCCGAGATGCACACCCTGCCGGTCCGCAAGTACGGCTACGAGTCCGGCCAGTTCCAGCGCATGAAAAAGGAACTCGCCGC
CCTCCCTCCGCCCGTCAAGAAAGCTGCCCCCCAACGATCGTCCCCGGCGGCAACGTTCCCGCCTCTCCCGCCAACTCCGG
GTGGAAGGAATACCATGCCCCGGCATTCACCCTCAGCTATCCCGAAGGCTGGCAGCCCTTAG

Upstream 100 bases:

>100_bases
TTGTACATCGTCGCCAAAGATGGGACCGGCAGTGCCTGGTCCCATCCTCTCACCGGCATCAATATGGAAAAATAATTGTA
TGCCCCGGGGGATCCCAACC

Downstream 100 bases:

>100_bases
GCGGTGACAACGGAGCCGACGTCACTTTCGCCCCAAAAGACGGCGTCGTCACCCGTGCCGGCAAAAGCCAAATCGGCTTC
GGCGCTGTCGCAGGAATCTT

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLLRNCAVGLLAIALATPAPAARRPGDPLKPGFNLFTKEDDISVGKENARQVLAQYDVVKNQFLQDYVNRIGKKLAAAPE
AEKSGFQFTFTVLNVDEINAFALPGGPMFIYTGLLKAIDNEAQLAGVMGHEMSHVILRQGTHEATKANGVQILAGGLATL
LGGGKLVQAGLGLTANSFVLKFSRDAESEADALGSHLMAESGYDPVQMAKFFEKLAAGGERMPQILSDHPNPGNREAAIA
AEMHTLPVRKYGYESGQFQRMKKELAALPPPVKKAAPQRSSPAATFPPLPPTPGGRNTMPRHSPSAIPKAGSP

Sequences:

>Translated_313_residues
MLLRNCAVGLLAIALATPAPAARRPGDPLKPGFNLFTKEDDISVGKENARQVLAQYDVVKNQFLQDYVNRIGKKLAAAPE
AEKSGFQFTFTVLNVDEINAFALPGGPMFIYTGLLKAIDNEAQLAGVMGHEMSHVILRQGTHEATKANGVQILAGGLATL
LGGGKLVQAGLGLTANSFVLKFSRDAESEADALGSHLMAESGYDPVQMAKFFEKLAAGGERMPQILSDHPNPGNREAAIA
AEMHTLPVRKYGYESGQFQRMKKELAALPPPVKKAAPQRSSPAATFPPLPPTPGGRNTMPRHSPSAIPKAGSP
>Mature_313_residues
MLLRNCAVGLLAIALATPAPAARRPGDPLKPGFNLFTKEDDISVGKENARQVLAQYDVVKNQFLQDYVNRIGKKLAAAPE
AEKSGFQFTFTVLNVDEINAFALPGGPMFIYTGLLKAIDNEAQLAGVMGHEMSHVILRQGTHEATKANGVQILAGGLATL
LGGGKLVQAGLGLTANSFVLKFSRDAESEADALGSHLMAESGYDPVQMAKFFEKLAAGGERMPQILSDHPNPGNREAAIA
AEMHTLPVRKYGYESGQFQRMKKELAALPPPVKKAAPQRSSPAATFPPLPPTPGGRNTMPRHSPSAIPKAGSP

Specific function: Unknown

COG id: COG4784

COG function: function code R; Putative Zn-dependent protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=166, Percent_Identity=29.5180722891566, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788840, Length=208, Percent_Identity=32.6923076923077, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082185, Length=162, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081800, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322940, Length=145, Percent_Identity=30.3448275862069, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 33256; Mature: 33256

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRNCAVGLLAIALATPAPAARRPGDPLKPGFNLFTKEDDISVGKENARQVLAQYDVVK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NQFLQDYVNRIGKKLAAAPEAEKSGFQFTFTVLNVDEINAFALPGGPMFIYTGLLKAIDN
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHCC
EAQLAGVMGHEMSHVILRQGTHEATKANGVQILAGGLATLLGGGKLVQAGLGLTANSFVL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEHHHHHHHHCCCHHHHHCCCCCCCCEEE
KFSRDAESEADALGSHLMAESGYDPVQMAKFFEKLAAGGERMPQILSDHPNPGNREAAIA
EECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHH
AEMHTLPVRKYGYESGQFQRMKKELAALPPPVKKAAPQRSSPAATFPPLPPTPGGRNTMP
HHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RHSPSAIPKAGSP
CCCCCCCCCCCCC
>Mature Secondary Structure
MLLRNCAVGLLAIALATPAPAARRPGDPLKPGFNLFTKEDDISVGKENARQVLAQYDVVK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NQFLQDYVNRIGKKLAAAPEAEKSGFQFTFTVLNVDEINAFALPGGPMFIYTGLLKAIDN
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHCC
EAQLAGVMGHEMSHVILRQGTHEATKANGVQILAGGLATLLGGGKLVQAGLGLTANSFVL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEHHHHHHHHCCCHHHHHCCCCCCCCEEE
KFSRDAESEADALGSHLMAESGYDPVQMAKFFEKLAAGGERMPQILSDHPNPGNREAAIA
EECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHH
AEMHTLPVRKYGYESGQFQRMKKELAALPPPVKKAAPQRSSPAATFPPLPPTPGGRNTMP
HHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
RHSPSAIPKAGSP
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]