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The map label for this gene is mdtA [H]

Identifier: 116624560

GI number: 116624560

Start: 6875466

End: 6876800

Strand: Direct

Name: mdtA [H]

Synonym: Acid_5484

Alternate gene names: 116624560

Gene position: 6875466-6876800 (Clockwise)

Preceding gene: 116624559

Following gene: 116624561

Centisome position: 68.99

GC content: 63.9

Gene sequence:

>1335_bases
ATGAAAAAGATGCCTTCCACAACTACTCAACTCGGCCTCGCCCTGTTGCTTCCCTTGCTGTTTACCTCCTGCTCGAAGAA
GGAAGAGAAGGAAGCCGAAGCTCCCCCGGGAGTGCAGGTGACGGCAGTCACGCAGGACACGATCCGCCGCGTGGTGGCGG
GCGACGGAGTGCTCTTTCCGCTCAATCAATCGAGCGTGGTGCCCAAGATCTCGGCGCCGGTGCAGCGCTTCCTGGTGCAG
CGCGGCGATCACGTGAAGCAGGGGCAACTGCTGGCGGTGCTGGAAAATCGCGATCTCGCAGCGGCGGAGGGCGAGAGCAA
GGCGCAGCTGGATCAGGCGCAGGCCAACCTTCGCTCCACGACATCGGCGCAGGTTCCCGAGTCGGTGGTGAAAGCACAAA
CCGACGTGGATTCCGCGCGGCAGGCCGAGGACGCCGCAAAGAAGTTGCTCGAGAACCGTCAGAAACTGTTGCAGCAGGGA
GCACTGGCGCGCAAGCTGGTGGACGATGCGCAGGTGGCCTACGCCCAGGCCCATGCGGCCTCGCTTTCGGCGCAGGAACA
CTTGCGCGTGCTTCAGTCCGTCGGCAAGCAGGAGCAGATCAAGACCGCCGAGGCGCAGGTGGACGCGGCGCGGAACCATC
TGCAATCCTCAGAGGCGCAGGTCGGCTATTCGCAGATTCGCAGCCCGATCGCGGGCGTGATCGCGGACCGTCCGTTGTAC
GCGGGCGAAATGGCTGCGCAGGGCACGCCGCTGCTGGTGGTGATGGATATCAGCAAGGTGATCGCCCGCGTCAACGTGCC
GCAGAACCAGGCGGCAACCGTGAAGGTCGGACAGCCGGCAAGCCTCACGCAGGTGGATTCCGATATCAAGGTGGAAGGCA
AGGTCGTGGTGGTGAGTCCCGCCACGGACCCGAACAGCACGACCGTACAGGTGTGGGTACAGGCCGATAATCCAGGCGAG
GTGCTCAAGCCGGGTACGAGCGTCCATGCGGCGATCATGACGGAGGTCATCAAGGCGGCGACGATCGTGCCGGCCAGCGC
GATTCTTCCCGGGGAAGAGGGCGGCATCTCCTGCCTGGTGGTGGATTCCAATTCGGTGACGCACCGGCGCACGGTGACGC
TCGGCGTGCGCGATGGCGATAAGGTACAGATCTTGAGCGGGCTGCAGCCGGGCGAGACGGTGGTGACGGTGGGCGGAGTC
GGCGTGGACGATAAGGCCAAAGTCCGAATCATCGACAACAGCAAGAAGGAAGCCGACGACGAAGACGAGAACGCTCCGCC
GGAGCCCGCAGCCAAGGACGCCAAGAAAGACGAGGCGAAGCCGAAAGCCAAATGA

Upstream 100 bases:

>100_bases
GACCACGGTGGCGGGCGCGCGCAATGCGTATGACGATGGGCTGGTGCGCTACCGTGCTGCTATCGCCAACATTCAAACCC
TGACGGGGGCCTTCTAGCCG

Downstream 100 bases:

>100_bases
GCGATTTTTCGACCAGCCCTCCCAGCACTCCTCCCAATCCGCCCGCGGGAGATACACCGCATTGGACCGCGCGGCACGGC
AAGCCCATCATATTCGTCAT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKKMPSTTTQLGLALLLPLLFTSCSKKEEKEAEAPPGVQVTAVTQDTIRRVVAGDGVLFPLNQSSVVPKISAPVQRFLVQ
RGDHVKQGQLLAVLENRDLAAAEGESKAQLDQAQANLRSTTSAQVPESVVKAQTDVDSARQAEDAAKKLLENRQKLLQQG
ALARKLVDDAQVAYAQAHAASLSAQEHLRVLQSVGKQEQIKTAEAQVDAARNHLQSSEAQVGYSQIRSPIAGVIADRPLY
AGEMAAQGTPLLVVMDISKVIARVNVPQNQAATVKVGQPASLTQVDSDIKVEGKVVVVSPATDPNSTTVQVWVQADNPGE
VLKPGTSVHAAIMTEVIKAATIVPASAILPGEEGGISCLVVDSNSVTHRRTVTLGVRDGDKVQILSGLQPGETVVTVGGV
GVDDKAKVRIIDNSKKEADDEDENAPPEPAAKDAKKDEAKPKAK

Sequences:

>Translated_444_residues
MKKMPSTTTQLGLALLLPLLFTSCSKKEEKEAEAPPGVQVTAVTQDTIRRVVAGDGVLFPLNQSSVVPKISAPVQRFLVQ
RGDHVKQGQLLAVLENRDLAAAEGESKAQLDQAQANLRSTTSAQVPESVVKAQTDVDSARQAEDAAKKLLENRQKLLQQG
ALARKLVDDAQVAYAQAHAASLSAQEHLRVLQSVGKQEQIKTAEAQVDAARNHLQSSEAQVGYSQIRSPIAGVIADRPLY
AGEMAAQGTPLLVVMDISKVIARVNVPQNQAATVKVGQPASLTQVDSDIKVEGKVVVVSPATDPNSTTVQVWVQADNPGE
VLKPGTSVHAAIMTEVIKAATIVPASAILPGEEGGISCLVVDSNSVTHRRTVTLGVRDGDKVQILSGLQPGETVVTVGGV
GVDDKAKVRIIDNSKKEADDEDENAPPEPAAKDAKKDEAKPKAK
>Mature_444_residues
MKKMPSTTTQLGLALLLPLLFTSCSKKEEKEAEAPPGVQVTAVTQDTIRRVVAGDGVLFPLNQSSVVPKISAPVQRFLVQ
RGDHVKQGQLLAVLENRDLAAAEGESKAQLDQAQANLRSTTSAQVPESVVKAQTDVDSARQAEDAAKKLLENRQKLLQQG
ALARKLVDDAQVAYAQAHAASLSAQEHLRVLQSVGKQEQIKTAEAQVDAARNHLQSSEAQVGYSQIRSPIAGVIADRPLY
AGEMAAQGTPLLVVMDISKVIARVNVPQNQAATVKVGQPASLTQVDSDIKVEGKVVVVSPATDPNSTTVQVWVQADNPGE
VLKPGTSVHAAIMTEVIKAATIVPASAILPGEEGGISCLVVDSNSVTHRRTVTLGVRDGDKVQILSGLQPGETVVTVGGV
GVDDKAKVRIIDNSKKEADDEDENAPPEPAAKDAKKDEAKPKAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=384, Percent_Identity=21.6145833333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081796, Length=375, Percent_Identity=24.8, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46879; Mature: 46879

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMPSTTTQLGLALLLPLLFTSCSKKEEKEAEAPPGVQVTAVTQDTIRRVVAGDGVLFP
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECHHHHHHHHCCCCEEEE
LNQSSVVPKISAPVQRFLVQRGDHVKQGQLLAVLENRDLAAAEGESKAQLDQAQANLRST
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
TSAQVPESVVKAQTDVDSARQAEDAAKKLLENRQKLLQQGALARKLVDDAQVAYAQAHAA
CCHHCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSAQEHLRVLQSVGKQEQIKTAEAQVDAARNHLQSSEAQVGYSQIRSPIAGVIADRPLY
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
AGEMAAQGTPLLVVMDISKVIARVNVPQNQAATVKVGQPASLTQVDSDIKVEGKVVVVSP
CCHHHCCCCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCCCHHCCCCCEEEEEEEEEEEC
ATDPNSTTVQVWVQADNPGEVLKPGTSVHAAIMTEVIKAATIVPASAILPGEEGGISCLV
CCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEE
VDSNSVTHRRTVTLGVRDGDKVQILSGLQPGETVVTVGGVGVDDKAKVRIIDNSKKEADD
ECCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCC
EDENAPPEPAAKDAKKDEAKPKAK
CCCCCCCCCCHHCCCHHCCCCCCC
>Mature Secondary Structure
MKKMPSTTTQLGLALLLPLLFTSCSKKEEKEAEAPPGVQVTAVTQDTIRRVVAGDGVLFP
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECHHHHHHHHCCCCEEEE
LNQSSVVPKISAPVQRFLVQRGDHVKQGQLLAVLENRDLAAAEGESKAQLDQAQANLRST
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
TSAQVPESVVKAQTDVDSARQAEDAAKKLLENRQKLLQQGALARKLVDDAQVAYAQAHAA
CCHHCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSAQEHLRVLQSVGKQEQIKTAEAQVDAARNHLQSSEAQVGYSQIRSPIAGVIADRPLY
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
AGEMAAQGTPLLVVMDISKVIARVNVPQNQAATVKVGQPASLTQVDSDIKVEGKVVVVSP
CCHHHCCCCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCCCHHCCCCCEEEEEEEEEEEC
ATDPNSTTVQVWVQADNPGEVLKPGTSVHAAIMTEVIKAATIVPASAILPGEEGGISCLV
CCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEE
VDSNSVTHRRTVTLGVRDGDKVQILSGLQPGETVVTVGGVGVDDKAKVRIIDNSKKEADD
ECCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCC
EDENAPPEPAAKDAKKDEAKPKAK
CCCCCCCCCCHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]