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The map label for this gene is macB [H]

Identifier: 116624542

GI number: 116624542

Start: 6851090

End: 6853798

Strand: Reverse

Name: macB [H]

Synonym: Acid_5466

Alternate gene names: 116624542

Gene position: 6853798-6851090 (Counterclockwise)

Preceding gene: 116624544

Following gene: 116624541

Centisome position: 68.77

GC content: 66.56

Gene sequence:

>2709_bases
ATGCTGCGAGAGTGGATTTCCCGGATTCGCGGAGTGGTATTGCGCCGGCGACTGGAGGAGGAATTCTCGAGCGAGGTGGA
AGCGCACCTGGCGTTGCTGGCGGAGGATCTGGTGCGGCGCGGCATGTCTCCCGAAGAGGCGTGCGGAGAAGCGCGGCGGC
AGTTCGGCGGCGTGACGCAAATCCAGGAATGGCATCGCGAAGGCCGTGGGATTGCCGCCCTGGACCACGCCGCGGCCGAC
CTGAAATACGCGCTGCGCATGATGCGGCGCAATCCCGGGTTCACGGCGGTCTCGGTGCTCACACTGGCGCTCGGGATCGG
AGTCAACACTACGCTGTTCTCGGCTTACAACGCGGTGGCGTTGAAGCCGCTGCCGGTGGCCGATCCGCAGCAGGTGGTAC
GGCTGGAACGCTGGTTCGCGAGCCGCGGCCGCGGCGATATTCAGTACGCATTCTCCTATCCCGAATACCTCTACCTTCGA
GACCACGGCCGGGCCTTCGCGGGAATGACTGCTTCCAGCTGGCCGGTGCGCGTTCTGGCTGCATGGCGCGGAGAGCGCGT
TGGCGACCGCCTGCAAGGGCATCTGGTCAGCGCCAATTACTTTTCGGCGATGGGAGTGGGCGCGCGCCTGGGGCGCTGCT
TCGCGGCGGATGAGGATCGAGTGCCGGGCGGCAATGCGCTCTTGGTGCTCAGCGCGGCGGCGTGGCGACAGCGCTTTCAT
GGCGATTCGCAGATTGTAGGACAGATCGTGAAATTGAATGGGACGGCCTTCACGGTGATCGGCGTGATGGACGAGAATTT
CACGGGCACTTCCGTGGTGCCGGCTGTCCCCGACTTTTGGGCGCCGCTCTCGATGCAGCAACAGCTGGCGCCGGGACGCA
ACTGGCTGGGCGACCCGGATGAGCCGATCTTCCAGATTCTGGCGCGCCTGCAGGTCGGAACCGGACTGGAGCGCGCACAG
GCCGAGGCGGAGCTGCTGCTGGGGCAGTTCAGCGCGACCCATGTCGAGCGCGATAAAACCACGTCGCTGACATTGCAGCC
GACCGCCTTCTTCGGCAATACCGAAGATCCGCGCTTCAAGGCGCTGGTCGCCGGGCTGATGCTGGTGGTGGGACTGGTGC
TGCTGGTGGCGTGCGCGAATATCGCCAACATGCTGCTGGCGCGCGGCGCGGGACGCCAGCGGGAAGTCGGATTGCGTCTG
GCGCTGGGCGCGGGCCGCGGACGCGTGATCCGCCAGTTGTTGACGGAGAGTATCGTGCTCGCGTTGGCGGGTGGGGCCGC
CGGGTTGCTGCTCTCGATCTGGAGCAGCCGGCTGCTGTGGGTGGCAATCGAGAGCCTGCTCTCGTTGCCCTTCGGCGGCG
GCACGCAACTCACCCTTGATCTCACGCCGGACGTGCGAGTTTATGCGTACGTGCTGGCGCTCTCGGTGGCCACCGGAATT
CTCTTCGGCCTGTCGCCGGCGCTGCAGTTCACGCGACCGGACCTGACCTCCGCGCTGAAGGACGAAGGTGCGTGCTTTGC
GCGCGGCTGGAACCGGTCGCGGATGCGGGGCTTCCTGGTGGGCAGCCAGGTGGCGGTATCGATGCTGCTCTTGATCACCA
CCGGCCTGCTGCTGCGCGGAATGACCCGCGCGCAGGTGGCAGAACCGGGGTTTGAGGCGCGCGGCCTCTATATGTTGACA
GCGGATTTTGGCGCCGACCCGGCGAAGGCGATCGCGCGGCAGCGCCGACTGCTGGAGCGCGTGAAGCTGGCGCCGGGCGT
GGCCGGCGCAGCTATCGGCGGGGTGCCGATGACGGGCACGTGGACCCCTCCGATGATCGCCGGCGAAGAGCGGGGACGCA
CGCTTGGAAGTTTTGCGGACGAGACATACCTGGCTACCGTCGGCGTCCCGCTGCTGCGCGGGCGCAACTTCACGAGAGCG
GAGGTGGAGCGCAGCGCGGCTGTGGCGGTGATCAGTGAAGGCGCCGCGCGACGGTTCTGGCCGGGTCGGGACGCGCTGGG
GCAGCGCTTCCAACTCGATATGAATTTCCGCGGCACGATGGCGGAGTTCGAAGTGGTCGGGGTGGTGAAGGATGTGCGAT
TCGCCAACGCGACCCGGCTCGACCCGGCGCACGTATACTTAATCGCCAAACCGCTTGGCTTCGAAAACATGCTGGTGCGC
GTGCGCGGTGAGGGCCCTGGGGCGCTGGCCGGCGTCAGGGCGGAAGTGGAAAAGGTGGACAGCGACCTGTTGCCGAGCCT
CGCGCTGATCAGCGTGGAAAGCGGACCGCTGCTGCTCCAGAAATTGCAGGTGCGTGTCCTCGCGGTTTTCGCGGGAGTCC
TGGCGGCCCTGGCGCTGCTGTTGGCGGGAGTCGGGATCTATGGTGTTATGGCGTACCTGGTCAGCCAGCGCACGCGGGAG
ATCGGGGTGCGCATGGCGCTGGGCGCCGCGGCGGGCGACGTGGTGCGCCACGTGGTGCTCGGCGGATTGCGTCCGGTGGC
GGTGGGGATCGCAGTTGGGATGGCGGGTGCGGCGGCGCTATCGGCGGTACTACATTCGACGCTTTCGTTCCCGGGCGCGG
CGGACCTTTTATATGGCGTAAGCTTTTACGACCCGGCGACCTTTATCGGACTGGCTGGATTTTTGATGGCCGTGGCCGGT
GTGGCGAGCCTGGTTCCGGCGTGGAGGGCGGTGCAGGTGGATCCGGTGGTGGCGTTAAAGTACGAATAA

Upstream 100 bases:

>100_bases
TCATCGGCGAAACCCGACAGAACTTGAATGATATTCCTGTTGACATTCAACAGGAAAGCGGACATACTTCTGTTGACGTT
CAACAGGGGGAGGGGAAGGC

Downstream 100 bases:

>100_bases
GAGAAGAGCGGTAGCAATATACTTGACGGACCTAATAACAAATCCGCCCCGGCGAGCGAAAGCGCCACTGCCTGCTCATG
CGGTCAGTCATGTCTACCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 902; Mature: 902

Protein sequence:

>902_residues
MLREWISRIRGVVLRRRLEEEFSSEVEAHLALLAEDLVRRGMSPEEACGEARRQFGGVTQIQEWHREGRGIAALDHAAAD
LKYALRMMRRNPGFTAVSVLTLALGIGVNTTLFSAYNAVALKPLPVADPQQVVRLERWFASRGRGDIQYAFSYPEYLYLR
DHGRAFAGMTASSWPVRVLAAWRGERVGDRLQGHLVSANYFSAMGVGARLGRCFAADEDRVPGGNALLVLSAAAWRQRFH
GDSQIVGQIVKLNGTAFTVIGVMDENFTGTSVVPAVPDFWAPLSMQQQLAPGRNWLGDPDEPIFQILARLQVGTGLERAQ
AEAELLLGQFSATHVERDKTTSLTLQPTAFFGNTEDPRFKALVAGLMLVVGLVLLVACANIANMLLARGAGRQREVGLRL
ALGAGRGRVIRQLLTESIVLALAGGAAGLLLSIWSSRLLWVAIESLLSLPFGGGTQLTLDLTPDVRVYAYVLALSVATGI
LFGLSPALQFTRPDLTSALKDEGACFARGWNRSRMRGFLVGSQVAVSMLLLITTGLLLRGMTRAQVAEPGFEARGLYMLT
ADFGADPAKAIARQRRLLERVKLAPGVAGAAIGGVPMTGTWTPPMIAGEERGRTLGSFADETYLATVGVPLLRGRNFTRA
EVERSAAVAVISEGAARRFWPGRDALGQRFQLDMNFRGTMAEFEVVGVVKDVRFANATRLDPAHVYLIAKPLGFENMLVR
VRGEGPGALAGVRAEVEKVDSDLLPSLALISVESGPLLLQKLQVRVLAVFAGVLAALALLLAGVGIYGVMAYLVSQRTRE
IGVRMALGAAAGDVVRHVVLGGLRPVAVGIAVGMAGAAALSAVLHSTLSFPGAADLLYGVSFYDPATFIGLAGFLMAVAG
VASLVPAWRAVQVDPVVALKYE

Sequences:

>Translated_902_residues
MLREWISRIRGVVLRRRLEEEFSSEVEAHLALLAEDLVRRGMSPEEACGEARRQFGGVTQIQEWHREGRGIAALDHAAAD
LKYALRMMRRNPGFTAVSVLTLALGIGVNTTLFSAYNAVALKPLPVADPQQVVRLERWFASRGRGDIQYAFSYPEYLYLR
DHGRAFAGMTASSWPVRVLAAWRGERVGDRLQGHLVSANYFSAMGVGARLGRCFAADEDRVPGGNALLVLSAAAWRQRFH
GDSQIVGQIVKLNGTAFTVIGVMDENFTGTSVVPAVPDFWAPLSMQQQLAPGRNWLGDPDEPIFQILARLQVGTGLERAQ
AEAELLLGQFSATHVERDKTTSLTLQPTAFFGNTEDPRFKALVAGLMLVVGLVLLVACANIANMLLARGAGRQREVGLRL
ALGAGRGRVIRQLLTESIVLALAGGAAGLLLSIWSSRLLWVAIESLLSLPFGGGTQLTLDLTPDVRVYAYVLALSVATGI
LFGLSPALQFTRPDLTSALKDEGACFARGWNRSRMRGFLVGSQVAVSMLLLITTGLLLRGMTRAQVAEPGFEARGLYMLT
ADFGADPAKAIARQRRLLERVKLAPGVAGAAIGGVPMTGTWTPPMIAGEERGRTLGSFADETYLATVGVPLLRGRNFTRA
EVERSAAVAVISEGAARRFWPGRDALGQRFQLDMNFRGTMAEFEVVGVVKDVRFANATRLDPAHVYLIAKPLGFENMLVR
VRGEGPGALAGVRAEVEKVDSDLLPSLALISVESGPLLLQKLQVRVLAVFAGVLAALALLLAGVGIYGVMAYLVSQRTRE
IGVRMALGAAAGDVVRHVVLGGLRPVAVGIAVGMAGAAALSAVLHSTLSFPGAADLLYGVSFYDPATFIGLAGFLMAVAG
VASLVPAWRAVQVDPVVALKYE
>Mature_902_residues
MLREWISRIRGVVLRRRLEEEFSSEVEAHLALLAEDLVRRGMSPEEACGEARRQFGGVTQIQEWHREGRGIAALDHAAAD
LKYALRMMRRNPGFTAVSVLTLALGIGVNTTLFSAYNAVALKPLPVADPQQVVRLERWFASRGRGDIQYAFSYPEYLYLR
DHGRAFAGMTASSWPVRVLAAWRGERVGDRLQGHLVSANYFSAMGVGARLGRCFAADEDRVPGGNALLVLSAAAWRQRFH
GDSQIVGQIVKLNGTAFTVIGVMDENFTGTSVVPAVPDFWAPLSMQQQLAPGRNWLGDPDEPIFQILARLQVGTGLERAQ
AEAELLLGQFSATHVERDKTTSLTLQPTAFFGNTEDPRFKALVAGLMLVVGLVLLVACANIANMLLARGAGRQREVGLRL
ALGAGRGRVIRQLLTESIVLALAGGAAGLLLSIWSSRLLWVAIESLLSLPFGGGTQLTLDLTPDVRVYAYVLALSVATGI
LFGLSPALQFTRPDLTSALKDEGACFARGWNRSRMRGFLVGSQVAVSMLLLITTGLLLRGMTRAQVAEPGFEARGLYMLT
ADFGADPAKAIARQRRLLERVKLAPGVAGAAIGGVPMTGTWTPPMIAGEERGRTLGSFADETYLATVGVPLLRGRNFTRA
EVERSAAVAVISEGAARRFWPGRDALGQRFQLDMNFRGTMAEFEVVGVVKDVRFANATRLDPAHVYLIAKPLGFENMLVR
VRGEGPGALAGVRAEVEKVDSDLLPSLALISVESGPLLLQKLQVRVLAVFAGVLAALALLLAGVGIYGVMAYLVSQRTRE
IGVRMALGAAAGDVVRHVVLGGLRPVAVGIAVGMAGAAALSAVLHSTLSFPGAADLLYGVSFYDPATFIGLAGFLMAVAG
VASLVPAWRAVQVDPVVALKYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=371, Percent_Identity=27.2237196765499, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 96659; Mature: 96659

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLREWISRIRGVVLRRRLEEEFSSEVEAHLALLAEDLVRRGMSPEEACGEARRQFGGVTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHH
IQEWHREGRGIAALDHAAADLKYALRMMRRNPGFTAVSVLTLALGIGVNTTLFSAYNAVA
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCEE
LKPLPVADPQQVVRLERWFASRGRGDIQYAFSYPEYLYLRDHGRAFAGMTASSWPVRVLA
ECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCEEECCCCCCCCCEEHH
AWRGERVGDRLQGHLVSANYFSAMGVGARLGRCFAADEDRVPGGNALLVLSAAAWRQRFH
HHCCCHHHHHHHCEEEECHHHHHHCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHC
GDSQIVGQIVKLNGTAFTVIGVMDENFTGTSVVPAVPDFWAPLSMQQQLAPGRNWLGDPD
CCHHHHHHHHEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
EPIFQILARLQVGTGLERAQAEAELLLGQFSATHVERDKTTSLTLQPTAFFGNTEDPRFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHH
ALVAGLMLVVGLVLLVACANIANMLLARGAGRQREVGLRLALGAGRGRVIRQLLTESIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
ALAGGAAGLLLSIWSSRLLWVAIESLLSLPFGGGTQLTLDLTPDVRVYAYVLALSVATGI
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LFGLSPALQFTRPDLTSALKDEGACFARGWNRSRMRGFLVGSQVAVSMLLLITTGLLLRG
HHHCCHHHHCCCCHHHHHHHCCCCEEECCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHC
MTRAQVAEPGFEARGLYMLTADFGADPAKAIARQRRLLERVKLAPGVAGAAIGGVPMTGT
CHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
WTPPMIAGEERGRTLGSFADETYLATVGVPLLRGRNFTRAEVERSAAVAVISEGAARRFW
CCCCCCCCCCCCCCHHHHCCCCEEHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PGRDALGQRFQLDMNFRGTMAEFEVVGVVKDVRFANATRLDPAHVYLIAKPLGFENMLVR
CCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEE
VRGEGPGALAGVRAEVEKVDSDLLPSLALISVESGPLLLQKLQVRVLAVFAGVLAALALL
EECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGVGIYGVMAYLVSQRTREIGVRMALGAAAGDVVRHVVLGGLRPVAVGIAVGMAGAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAVLHSTLSFPGAADLLYGVSFYDPATFIGLAGFLMAVAGVASLVPAWRAVQVDPVVALK
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCEEEEE
YE
CC
>Mature Secondary Structure
MLREWISRIRGVVLRRRLEEEFSSEVEAHLALLAEDLVRRGMSPEEACGEARRQFGGVTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHH
IQEWHREGRGIAALDHAAADLKYALRMMRRNPGFTAVSVLTLALGIGVNTTLFSAYNAVA
HHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCCEE
LKPLPVADPQQVVRLERWFASRGRGDIQYAFSYPEYLYLRDHGRAFAGMTASSWPVRVLA
ECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCEEECCCCCCCCCEEHH
AWRGERVGDRLQGHLVSANYFSAMGVGARLGRCFAADEDRVPGGNALLVLSAAAWRQRFH
HHCCCHHHHHHHCEEEECHHHHHHCHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHC
GDSQIVGQIVKLNGTAFTVIGVMDENFTGTSVVPAVPDFWAPLSMQQQLAPGRNWLGDPD
CCHHHHHHHHEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCC
EPIFQILARLQVGTGLERAQAEAELLLGQFSATHVERDKTTSLTLQPTAFFGNTEDPRFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHH
ALVAGLMLVVGLVLLVACANIANMLLARGAGRQREVGLRLALGAGRGRVIRQLLTESIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
ALAGGAAGLLLSIWSSRLLWVAIESLLSLPFGGGTQLTLDLTPDVRVYAYVLALSVATGI
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LFGLSPALQFTRPDLTSALKDEGACFARGWNRSRMRGFLVGSQVAVSMLLLITTGLLLRG
HHHCCHHHHCCCCHHHHHHHCCCCEEECCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHC
MTRAQVAEPGFEARGLYMLTADFGADPAKAIARQRRLLERVKLAPGVAGAAIGGVPMTGT
CHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
WTPPMIAGEERGRTLGSFADETYLATVGVPLLRGRNFTRAEVERSAAVAVISEGAARRFW
CCCCCCCCCCCCCCHHHHCCCCEEHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
PGRDALGQRFQLDMNFRGTMAEFEVVGVVKDVRFANATRLDPAHVYLIAKPLGFENMLVR
CCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEE
VRGEGPGALAGVRAEVEKVDSDLLPSLALISVESGPLLLQKLQVRVLAVFAGVLAALALL
EECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGVGIYGVMAYLVSQRTREIGVRMALGAAAGDVVRHVVLGGLRPVAVGIAVGMAGAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAVLHSTLSFPGAADLLYGVSFYDPATFIGLAGFLMAVAGVASLVPAWRAVQVDPVVALK
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCEEEEE
YE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA