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The map label for this gene is rpoC

Identifier: 116624532

GI number: 116624532

Start: 6833207

End: 6837418

Strand: Reverse

Name: rpoC

Synonym: Acid_5456

Alternate gene names: 116624532

Gene position: 6837418-6833207 (Counterclockwise)

Preceding gene: 116624533

Following gene: 116624531

Centisome position: 68.61

GC content: 60.94

Gene sequence:

>4212_bases
TTGAGATCCTCTCCGTATGATCGTGCGAATTTGATCGCGGATTTTGATTCGATCCGCATTTCTCTGGCCTCTCCGGAAAA
AATCCGGAGCTGGTCGCATGGGGAAGTCACCAAGCCGGAGACCATCAACTACCGGACCTTTAAGCCGGAGCGCGACGGAC
TCTTCTGCGCGCGTATTTTCGGCCCCACCCAGGATTGGGAGTGCTTGTGCGGCAAGTATAAGCGCATGAAGCACCGCGGC
GTTATTTGCGACAAGTGCGGCGTGGAAGTCACGCTGGCGCGCGTTCGCCGTGAGCGCCTTGGACATATCGAACTGGCCAG
CCCGTGCTCGCACGTGTGGTTCTTCAAGGGACTGCCGAGCCGCATCGGGCACCTGCTGGACATCACGCTGCGCGAACTGG
AGCGCGTGCTCTATTTCGAAGCTTACGTGATCGTGGATCCGGGCGACGGCACCGGGCTCAGCAGCGGCGAAGTAATCACG
GACGAGCGCAAGCGGCAGCTCGACCAGGAATTCCCGGGCAAGTTCATCGCGATGATGGGCGCCGAGGGAATCAAGGAACT
GCTCAAGAAGATCGACGTCGAGTCGCTCAGCGAAGAGATTCGCGAGAAGATGAAGACCGAGCAGAGCCAGCAGAAAAAAC
TGAAGCACGCCAAGCGCTTGCGCGTGGTGGAAAGCTTCCGCAAGAGCGGCAACAAGCCGGAGTGGATGATTCTGGACGTC
ATCCCGGTAATTCCGCCGGAGTTGCGCCCGCTGGTGCCGTTGGACGGCGGCCGTTTCGCGACCTCCGATTTGAATGATCT
CTACCGCCGCGTGATCAACCGCAACAACCGGTTGAAGAAGCTGATCGAGCTGCACGCGCCGGACGTGATCGTGCGCAACG
AAAAGCGCATGCTGCAGGAAGCCGTGGACGCGCTGTTCGACAACGGACGCCGTGGACGCGTGCTGCGCGGCGCCAACAAC
CGCCCGCTGAAATCGCTCTCCGACACGTTGAAGGGCAAGCAGGGCCGTTTCCGCCAGAACCTGCTCGGCAAGCGCGTGGA
TTACTCGGGCCGTTCCGTAATCGTCGTCGGCCCCGACCTGAAGCTGCATCAGTGCGGTCTTCCCAAGAAGATGGCGCTGG
AACTGTTCAAGCCGTTCATTTATCACCGGCTCGAGCAGCGTGGTCATTGCACCACCATCAAGCAAGCCAAGGAACTGGTG
GAGCAGCAGGATCCGGTGGTTTGGGACATTTTGGAAGAGGTGATCAAGGACCATCCGATCATGCTCAACCGCGCTCCCAC
GCTGCACCGCCTCGGCATCCAGGCCTTCGAGCCGGTGCTGGTGGAAGGCAAGGCGATCAAGATCCACCCGCTGGTCTGCA
CCGCGTTCAACGCGGATTTCGACGGCGACCAGATGGCGGTACATATTCCGCTGTCGCCCGAAGCGCAGATCGAAGCTTCG
ACGCTGATGCTTTCGGCGAATAACATTCTGTCGCCGGCGCACGGCGGACCGATCACGATCCCGACGCAGGACATGGTGCT
GGGCTGCTACTACCTGACCAAGTCGCGGCCGGGCGCGAAGGGCGAAGGGCGAACGTTCGCATCCACGGACGACGTTTTGA
TCGCGCTCGAAATGGGCGAAGTCGAGACGCTGACGCCGATCAAACTGCGCTACACCGGCAAGGTGATCGACTTGGTGCAC
GCCTTCGACACGCAGAACATTCTTCACACGGAACCGATCGAGTTCATCAAGCAGTACATGGATACGACGGTGGGCCGCGT
GATTCTCAACGACAACCTGCCGCAGGACATGCCGTACATCAACGGCCTTCTGAAGAAGAAGGGCCTGGCGCAGCTGGTGC
AGTATTGCTACCTCAAGTTCGGCCTGCACGTAACCGTGCACATGCTGGACGAGATCAAGAGCCTGGGCTTCCTGTACGCT
ACGCGGGCGGGCATTTCGATCGGCATCGACGACATGGTCGTCCCGAGCGAGAAGGCCGGCCTGGTGCGCGACGCCGAGAA
GGAAGTGGTGCTCGTGGAAAACCAGTATCAGGACGGCGCCATCACGCACGGCGAACGCTATAACAAGATCATCGAAATCT
GGAGTAAGGTTACCGAACGGGTCTCCGATGAGATGTTCACGGCGATGGAAGAGGACGACCGTACGGGCCGCTACCTCAAC
CCGATTTACATCATGGCCGACTCCGGCGCGCGCGGATCGAAACAGCAGATCCGCCAGCTTTCCGGTATGCGCGGTTTGAT
GGCCAAGCCGTCGGGCGAAATTATCGAAACCCCGATCACGGCCAACTTCCGCGAAGGTCTGAACGTGCTGCAATACTTCA
TCTCGACGCACGGCGCCCGCAAGGGGCTGGCCGATACGGCGTTGAAGACGGCGGATTCGGGCTACCTGACCCGGCGCCTG
GTGGACGTGGCGCAGGACGTGATCATCAGCGAGAACGATTGCGGCACCACGGAAGGCATTTACGTGGAGCCGATCATCGA
ATCCGGCGAAATCATCGAAGCCCTGCGCGACCGCATTGTGGGCCGCGTGGCGCTCGAAGACCAGAAGGATTACGAAGGCA
ACGTGATCGTCGGGGTCAACCAGGAGATCACGGAAGACCTGGCGGCGGCGATTCAGGCGGCTGGTATCGAGCGTGTGAAG
ATCCGCTCGGTGTTGACGTGCGAATCGAAGCGCGGCGTTTGCGTGGCGTGCTACGGCCGCAACCTGGCGACGGGACGGCT
GGTGGAGCGCGGCGAAGCCGTGGGCGTGATCGCGGCGCAATCGATCGGCGAACCGGGAACGCAGTTGACGATGCGTACGT
TCCACATCGGTGGTACGGCGACCCGAATCAACGAGCAGAGCAAGCAGGACGCCAAGAGCGACGGTTTCGCCCGGTACATC
GGGATCCAGACCGTGCGTTCGAAGGTGGGCGAACTGATCGCGATGAACCGCAACGGCATCATGGCGGTGGTCGATGACAA
GGGTCGCGAAAAGGAACGCTACCCCGCGGTGTACGGCGCGCGCGTGCTGGTGGAAGACGGCGCTCCGGTGAAGAGCAACC
AGGTGCTGCTCGAGTGGGATCCTTACACGTTCTCGATTCTGACGGAAGTCAGCGGCGTGGTGCACTTTAAGGACCTGATC
GACGGCCTGACGATGCAGGAGCGGCTGGACGAAGTCACGGGCATGTCGCAGTTGGTGGTGATCGATTCCCCCGACGAAAA
GCGGCAGCCGATGATTCAGGTTCGGCCGGAAGGCGCGACGGGACGTGGTTCGGAAGCCAAGAAGTACCTGATGCCGACCC
ACGCTCACTTGATGGTTCGCGATGGAGAGGAACTCCACGCCGGCGACGTGCTGGCGAAGATCCCGCGCGAAACCACGAAG
ACCAAGGACATCACCGGCGGTCTGCCGCGCGTGGTGGAACTGTTCGAAGCGCGCAAGCCGCGTGAGACGGCCATCATCGC
GGAGATCAACGGCACCGTGAAGTACGGCGAAGTCACCAAGGGCCAGCGCAAGATCTACGTGGAAGGCGAAGACGGCGAGA
AGCGCGAGTACGCGCTGCCCCGCGGTGTGCACATCAACGTCCAGGAAGGCGAGAAGGTCAAGGCCGGCGAGCCTTTGATG
GACGGACCGCGCGACCCGCACGATATTCTGGCGGTGCTCGGCGAGAAGGAACTGCAGAAGTACCTGGTGAACGAAATCCA
GGAAGTTTACCGGTTGCAGGGCGTGAATATCAACGATAAACATCTCGAGACGATCTCGCGGCAGATGATGCGGTGGGTGA
AGGTCGAGGACATCGGGGATACGGAATTCCTGCCGGAAGAGATCGTGGACAAGTTCAAGTTCCGCACGGAAAACAACAAG
GTGCTGGAAGCAGGCGGGCGACCGGCGCAGGGTAAGGCTATGCTGTTGGGTATCACGAAGGCCTCGCTCTCGACGGATTC
GTTCATCTCGGCGGCCAGCTTCCAGGAGACCACGCGCGTACTCACCGAAGCCGCGATCAACGGCAAGGTGGATTATCTGC
GCGGTCTGAAGGAAAACGTGATCATGGGGCGCCTGGTTCCTGCCGGCACCGGCATGGAGTATTACCGCCAGGTGAAGATC
GCGGGCGAGGATGTGGTGGAAGAGCCAGTGGCGGAGCCGCTGGACATCATCCCCGGTTACGATGAGGAGACCCGGCTGCA
GTATGCCGGCGGACTTCCGGAGGACACCGGCGAAGAATCCCTCGCGGAGTAG

Upstream 100 bases:

>100_bases
GATAAACGCAGACAAAACAAAAGGATTTTTCTTGTCTGTGTTTATCTGTGTTCATCTGCCGGCTAACAAAGTTTTAGGTT
TCTAGGAACTGGAGGCAATT

Downstream 100 bases:

>100_bases
TTGTAGTACAATTCAACCGCCGGCGCGCCTGTATGGTGTGCCGGCGGTCTTGTATTTTGGAGGTGGATCATGAACGAAAT
CATCTTCATCGTCAGCGAGC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1403; Mature: 1403

Protein sequence:

>1403_residues
MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIFGPTQDWECLCGKYKRMKHRG
VICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPSRIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVIT
DERKRQLDQEFPGKFIAMMGAEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDV
IPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQEAVDALFDNGRRGRVLRGANN
RPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELV
EQQDPVVWDILEEVIKDHPIMLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEAS
TLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGEVETLTPIKLRYTGKVIDLVH
AFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYINGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYA
TRAGISIGIDDMVVPSEKAGLVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLN
PIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTADSGYLTRRL
VDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIVGRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVK
IRSVLTCESKRGVCVACYGRNLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYI
GIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWDPYTFSILTEVSGVVHFKDLI
DGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGATGRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTK
TKDITGGLPRVVELFEARKPRETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLM
DGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGDTEFLPEEIVDKFKFRTENNK
VLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRVLTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKI
AGEDVVEEPVAEPLDIIPGYDEETRLQYAGGLPEDTGEESLAE

Sequences:

>Translated_1403_residues
MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIFGPTQDWECLCGKYKRMKHRG
VICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPSRIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVIT
DERKRQLDQEFPGKFIAMMGAEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDV
IPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQEAVDALFDNGRRGRVLRGANN
RPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELV
EQQDPVVWDILEEVIKDHPIMLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEAS
TLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGEVETLTPIKLRYTGKVIDLVH
AFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYINGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYA
TRAGISIGIDDMVVPSEKAGLVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLN
PIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTADSGYLTRRL
VDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIVGRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVK
IRSVLTCESKRGVCVACYGRNLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYI
GIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWDPYTFSILTEVSGVVHFKDLI
DGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGATGRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTK
TKDITGGLPRVVELFEARKPRETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLM
DGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGDTEFLPEEIVDKFKFRTENNK
VLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRVLTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKI
AGEDVVEEPVAEPLDIIPGYDEETRLQYAGGLPEDTGEESLAE
>Mature_1403_residues
MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIFGPTQDWECLCGKYKRMKHRG
VICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPSRIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVIT
DERKRQLDQEFPGKFIAMMGAEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDV
IPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQEAVDALFDNGRRGRVLRGANN
RPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELV
EQQDPVVWDILEEVIKDHPIMLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEAS
TLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGEVETLTPIKLRYTGKVIDLVH
AFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYINGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYA
TRAGISIGIDDMVVPSEKAGLVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLN
PIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTADSGYLTRRL
VDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIVGRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVK
IRSVLTCESKRGVCVACYGRNLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYI
GIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWDPYTFSILTEVSGVVHFKDLI
DGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGATGRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTK
TKDITGGLPRVVELFEARKPRETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLM
DGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGDTEFLPEEIVDKFKFRTENNK
VLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRVLTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKI
AGEDVVEEPVAEPLDIIPGYDEETRLQYAGGLPEDTGEESLAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=850, Percent_Identity=26.3529411764706, Blast_Score=188, Evalue=3e-47,
Organism=Homo sapiens, GI39725938, Length=904, Percent_Identity=24.6681415929204, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI103471997, Length=751, Percent_Identity=24.3675099866844, Blast_Score=118, Evalue=5e-26,
Organism=Escherichia coli, GI2367335, Length=1366, Percent_Identity=56.6617862371889, Blast_Score=1548, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=909, Percent_Identity=24.972497249725, Blast_Score=179, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI25145495, Length=679, Percent_Identity=27.540500736377, Blast_Score=174, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320061, Length=926, Percent_Identity=25.1619870410367, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324690, Length=572, Percent_Identity=26.7482517482518, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17530899, Length=928, Percent_Identity=24.3534482758621, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281360912, Length=662, Percent_Identity=26.4350453172205, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17647875, Length=329, Percent_Identity=25.8358662613982, Blast_Score=99, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_SOLUE (Q01VB2)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826688.1
- ProteinModelPortal:   Q01VB2
- STRING:   Q01VB2
- GeneID:   4426321
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5456
- NMPDR:   fig|234267.9.peg.5188
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q01VB2
- ProtClustDB:   PRK00566
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 156898; Mature: 156898

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIF
CCCCCCCCHHHEEECCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEC
GPTQDWECLCGKYKRMKHRGVICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPS
CCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHCCCHH
RIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVITDERKRQLDQEFPGKFIAMMG
HHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHC
AEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQE
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHHH
AVDALFDNGRRGRVLRGANNRPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDL
HHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCC
KLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELVEQQDPVVWDILEEVIKDHPI
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
MLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEAS
EEECCCCHHHHCHHHHCCEEECCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCEEEE
TLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGE
EEEEECCCCCCCCCCCCEEECCHHHHEEEEEEECCCCCCCCCCCEECCCCCEEEEEECCC
VETLTPIKLRYTGKVIDLVHAFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYI
CCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCHHH
NGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYATRAGISIGIDDMVVPSEKAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCCCCCCCC
LVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLN
CCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
PIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTADSGYLTRRLVDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIV
CCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVKIRSVLTCESKRGVCVACYGR
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEHHHHEEECCCCCEEEEEECC
NLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYI
CCCCCHHHHCCCEEEEEEHHCCCCCCCEEEEEEEEECCCHHHCCCHHHHHHCCCCCCHHH
GIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWD
HHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCHHHCCEEEEECCCCCCCCEEEEEEC
PYTFSILTEVSGVVHFKDLIDGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGAT
CCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCC
GRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTKTKDITGGLPRVVELFEARKP
CCCCCCHHHCCCCCEEEEEECCCCCCCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHCCCC
RETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLM
CCEEEEEEECCEEEECCCCCCCEEEEEECCCCCCHHCCCCCCEEEEECCCCEECCCCCCC
DGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGD
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
TEFLPEEIVDKFKFRTENNKVLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRV
CCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKIAGEDVVEEPVAEPLDIIPGY
HHHHHHCCCHHHHHHHHHHHHEEEEECCCCCHHHHHEEEECCHHHHHHHHCCCHHHCCCC
DEETRLQYAGGLPEDTGEESLAE
CCHHHEEECCCCCCCCCCHHHCC
>Mature Secondary Structure
MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIF
CCCCCCCCHHHEEECCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEC
GPTQDWECLCGKYKRMKHRGVICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPS
CCCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHCCCHH
RIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVITDERKRQLDQEFPGKFIAMMG
HHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECCHHHHHHHHHCCCHHHHHHC
AEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQE
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHHH
AVDALFDNGRRGRVLRGANNRPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDL
HHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCC
KLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELVEQQDPVVWDILEEVIKDHPI
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCE
MLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEAS
EEECCCCHHHHCHHHHCCEEECCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCEEEE
TLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGE
EEEEECCCCCCCCCCCCEEECCHHHHEEEEEEECCCCCCCCCCCEECCCCCEEEEEECCC
VETLTPIKLRYTGKVIDLVHAFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYI
CCCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCHHH
NGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYATRAGISIGIDDMVVPSEKAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCCCCCCCC
LVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLN
CCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEC
PIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTADSGYLTRRLVDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIV
CCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVKIRSVLTCESKRGVCVACYGR
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEHHHHEEECCCCCEEEEEECC
NLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYI
CCCCCHHHHCCCEEEEEEHHCCCCCCCEEEEEEEEECCCHHHCCCHHHHHHCCCCCCHHH
GIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWD
HHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCHHHCCEEEEECCCCCCCCEEEEEEC
PYTFSILTEVSGVVHFKDLIDGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGAT
CCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCC
GRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTKTKDITGGLPRVVELFEARKP
CCCCCCHHHCCCCCEEEEEECCCCCCCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHCCCC
RETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLM
CCEEEEEEECCEEEECCCCCCCEEEEEECCCCCCHHCCCCCCEEEEECCCCEECCCCCCC
DGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGD
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
TEFLPEEIVDKFKFRTENNKVLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRV
CCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKIAGEDVVEEPVAEPLDIIPGY
HHHHHHCCCHHHHHHHHHHHHEEEEECCCCCHHHHHEEEECCHHHHHHHHCCCHHHCCCC
DEETRLQYAGGLPEDTGEESLAE
CCHHHEEECCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA