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The map label for this gene is cat2 [H]

Identifier: 116624501

GI number: 116624501

Start: 6794237

End: 6795559

Strand: Reverse

Name: cat2 [H]

Synonym: Acid_5425

Alternate gene names: 116624501

Gene position: 6795559-6794237 (Counterclockwise)

Preceding gene: 116624502

Following gene: 116624500

Centisome position: 68.19

GC content: 64.17

Gene sequence:

>1323_bases
ATGAGGAACGATTACCGGTCGCGGATCATGCCCGCGGATGTGGCGCTCGCGGAACTGCACAGCGGCCAGCGCGTCTACGT
GCACAATGGCTGCGGAGAGCCGGTAGAACTGGTAAAGGCGCTGACGCGGCGCGGCCCGGAACTGGAAGACGTGGAGGTGC
TCCACATGGCGACCATGGGGATCGCCGACTACATTCTTCCCGAGTACGAGGGCCACTTCCGGCACAACGCCCTTTTCATC
GGCGGCAACGTGCGCAAGGCGGTGCAGGAAGGGCGCGCGGATTACACGCCGATTTTCCTGAGCGAAATCGAAGCGCTGTT
CACGTCTGGCGCGCTGCCGATCGACGTCTGCCTGCTGCAGTGCACGCCGCCCGACCCCTACGGGTACATGAGCCTGGGGC
CGAGCATCGACGCATCACTGACGGCCGCGCAGTGCGCCCGCCACGTGATCGTAGAGATCAACGACCAGTGCCCGCGCACG
CTCGGCGACACCTTCATCCACGTGAGCAGGGTGGACGCGTTCGTGGAGACGTCGCACCCGCTGAGCGAATATCCGCGGCC
GCCCGTGACGGATCTGCAGCGCGCGATCGGACGTCACGTGGCGGCGCTGATTCCCGATGGGGCCACGATTCAGACCGGGA
TCGGCGGGATTCCCGAGGCGGTGCTCGGCATGCTACGCGACCGCAAGGATCTGGGGATCCACAGCGAGATGGTTCCCGAT
TCCGTAATCGATCTGATCAAGGCGGGCGTGATCAATGGCGATCGCAAGACGCTGCACCCGCACAAAGTGATTGCCGGGTT
CGTGCTGGGCAGCAAAGTGCTCTTCGATTTCATCGACAATAATCCGACCTTCGAATTCCATCGCACGGCATATTGCAACG
ACCCGGGGATCATCGCGCAGAATGAGCGGATGGTGGCGATCAATTCGGCGATCGAGGTGGATTTGACGGGACAGGTCTGC
TCGGACTCGATGGGCACGGCTCCGTACAGCGGCATCGGCGGCCAGGTGGATTTCCTGCGCGGGGCGGCGCGCTCCAAGGG
CGGGCTGCCGATCATCACGCTGCCTTCCACCGCGAAGGGCGGCGCGCTCTCCCGCATCGTCCCGACGCTGCAGCCGGGCG
CCGGTGTGGTGACCTCGCGCGGCGACGTGCATTACGTGATCACGGAGAATGGCGTGGCGTACCTGCACGGCAAAACGATC
CGGCAGCGGGCAGAGGCGATGATCGCCATCGCCCATCCCCAATTCCAGCAGGAGTTGGAGGAGTATGCAGTAAAGAGCAA
GCTGCTGACCGCGAGCCCTAGTCTGGTCGGAGTGCGGGCTTAA

Upstream 100 bases:

>100_bases
TGCCTTACGTATTGACCATCGCCAAACACGGTGTCGCCGGCGCATTCGAAAAATGCTCGGAACTGGCGCGCGGCGTGTAC
TTGATCGAGGGGAAACGGCC

Downstream 100 bases:

>100_bases
CCCCAGCGGCCCTGAGGGCGCAAGGCCTCAGAACGAGCCGCGACCGTGAGGGAGCGCTACCCCCACAATACCTGCCGTTC
GCGAGGCTGATCCGCCTTCA

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRNDYRSRIMPADVALAELHSGQRVYVHNGCGEPVELVKALTRRGPELEDVEVLHMATMGIADYILPEYEGHFRHNALFI
GGNVRKAVQEGRADYTPIFLSEIEALFTSGALPIDVCLLQCTPPDPYGYMSLGPSIDASLTAAQCARHVIVEINDQCPRT
LGDTFIHVSRVDAFVETSHPLSEYPRPPVTDLQRAIGRHVAALIPDGATIQTGIGGIPEAVLGMLRDRKDLGIHSEMVPD
SVIDLIKAGVINGDRKTLHPHKVIAGFVLGSKVLFDFIDNNPTFEFHRTAYCNDPGIIAQNERMVAINSAIEVDLTGQVC
SDSMGTAPYSGIGGQVDFLRGAARSKGGLPIITLPSTAKGGALSRIVPTLQPGAGVVTSRGDVHYVITENGVAYLHGKTI
RQRAEAMIAIAHPQFQQELEEYAVKSKLLTASPSLVGVRA

Sequences:

>Translated_440_residues
MRNDYRSRIMPADVALAELHSGQRVYVHNGCGEPVELVKALTRRGPELEDVEVLHMATMGIADYILPEYEGHFRHNALFI
GGNVRKAVQEGRADYTPIFLSEIEALFTSGALPIDVCLLQCTPPDPYGYMSLGPSIDASLTAAQCARHVIVEINDQCPRT
LGDTFIHVSRVDAFVETSHPLSEYPRPPVTDLQRAIGRHVAALIPDGATIQTGIGGIPEAVLGMLRDRKDLGIHSEMVPD
SVIDLIKAGVINGDRKTLHPHKVIAGFVLGSKVLFDFIDNNPTFEFHRTAYCNDPGIIAQNERMVAINSAIEVDLTGQVC
SDSMGTAPYSGIGGQVDFLRGAARSKGGLPIITLPSTAKGGALSRIVPTLQPGAGVVTSRGDVHYVITENGVAYLHGKTI
RQRAEAMIAIAHPQFQQELEEYAVKSKLLTASPSLVGVRA
>Mature_440_residues
MRNDYRSRIMPADVALAELHSGQRVYVHNGCGEPVELVKALTRRGPELEDVEVLHMATMGIADYILPEYEGHFRHNALFI
GGNVRKAVQEGRADYTPIFLSEIEALFTSGALPIDVCLLQCTPPDPYGYMSLGPSIDASLTAAQCARHVIVEINDQCPRT
LGDTFIHVSRVDAFVETSHPLSEYPRPPVTDLQRAIGRHVAALIPDGATIQTGIGGIPEAVLGMLRDRKDLGIHSEMVPD
SVIDLIKAGVINGDRKTLHPHKVIAGFVLGSKVLFDFIDNNPTFEFHRTAYCNDPGIIAQNERMVAINSAIEVDLTGQVC
SDSMGTAPYSGIGGQVDFLRGAARSKGGLPIITLPSTAKGGALSRIVPTLQPGAGVVTSRGDVHYVITENGVAYLHGKTI
RQRAEAMIAIAHPQFQQELEEYAVKSKLLTASPSLVGVRA

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=448, Percent_Identity=24.5535714285714, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=424, Percent_Identity=42.688679245283, Blast_Score=343, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI17538151, Length=423, Percent_Identity=42.3167848699764, Blast_Score=335, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6319456, Length=399, Percent_Identity=24.3107769423559, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358615, Length=431, Percent_Identity=45.9396751740139, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47495; Mature: 47495

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNDYRSRIMPADVALAELHSGQRVYVHNGCGEPVELVKALTRRGPELEDVEVLHMATMG
CCCCHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
IADYILPEYEGHFRHNALFIGGNVRKAVQEGRADYTPIFLSEIEALFTSGALPIDVCLLQ
HHHHHCCCCCCCEECCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
CTPPDPYGYMSLGPSIDASLTAAQCARHVIVEINDQCPRTLGDTFIHVSRVDAFVETSHP
ECCCCCCCCEECCCCCCCHHHHHHHHCEEEEEECCCCCHHHHHHEEEHHHHHHHHHCCCC
LSEYPRPPVTDLQRAIGRHVAALIPDGATIQTGIGGIPEAVLGMLRDRKDLGIHSEMVPD
HHHCCCCCHHHHHHHHHHHHEECCCCCCEEECCCCCCHHHHHHHHHCCHHCCCCHHCCCH
SVIDLIKAGVINGDRKTLHPHKVIAGFVLGSKVLFDFIDNNPTFEFHRTAYCNDPGIIAQ
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEC
NERMVAINSAIEVDLTGQVCSDSMGTAPYSGIGGQVDFLRGAARSKGGLPIITLPSTAKG
CCEEEEECCEEEEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCC
GALSRIVPTLQPGAGVVTSRGDVHYVITENGVAYLHGKTIRQRAEAMIAIAHPQFQQELE
CCHHHHCCCCCCCCCEEECCCCEEEEEECCCEEEEECHHHHHHHHEEEEEECHHHHHHHH
EYAVKSKLLTASPSLVGVRA
HHHHHHHHEECCCCEEEECC
>Mature Secondary Structure
MRNDYRSRIMPADVALAELHSGQRVYVHNGCGEPVELVKALTRRGPELEDVEVLHMATMG
CCCCHHHCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
IADYILPEYEGHFRHNALFIGGNVRKAVQEGRADYTPIFLSEIEALFTSGALPIDVCLLQ
HHHHHCCCCCCCEECCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE
CTPPDPYGYMSLGPSIDASLTAAQCARHVIVEINDQCPRTLGDTFIHVSRVDAFVETSHP
ECCCCCCCCEECCCCCCCHHHHHHHHCEEEEEECCCCCHHHHHHEEEHHHHHHHHHCCCC
LSEYPRPPVTDLQRAIGRHVAALIPDGATIQTGIGGIPEAVLGMLRDRKDLGIHSEMVPD
HHHCCCCCHHHHHHHHHHHHEECCCCCCEEECCCCCCHHHHHHHHHCCHHCCCCHHCCCH
SVIDLIKAGVINGDRKTLHPHKVIAGFVLGSKVLFDFIDNNPTFEFHRTAYCNDPGIIAQ
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEC
NERMVAINSAIEVDLTGQVCSDSMGTAPYSGIGGQVDFLRGAARSKGGLPIITLPSTAKG
CCEEEEECCEEEEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCC
GALSRIVPTLQPGAGVVTSRGDVHYVITENGVAYLHGKTIRQRAEAMIAIAHPQFQQELE
CCHHHHCCCCCCCCCEEECCCCEEEEEECCCEEEEECHHHHHHHHEEEEEECHHHHHHHH
EYAVKSKLLTASPSLVGVRA
HHHHHHHHEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]