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The map label for this gene is phhB

Identifier: 116624321

GI number: 116624321

Start: 6574106

End: 6574393

Strand: Direct

Name: phhB

Synonym: Acid_5239

Alternate gene names: NA

Gene position: 6574106-6574393 (Clockwise)

Preceding gene: 116624318

Following gene: 116624325

Centisome position: 65.97

GC content: 56.6

Gene sequence:

>288_bases
ATGACCACTAAACTCTCCGAATCCGAGATCCAGTCGGCTCTGCGCGAGCGGAGCGCCTGGACCGTGGTAAATGGCAAGCT
GCATCGCGAATATAAGTTCGCTGATTTTATCCACGCGTTCGGCTTCATGACATGCGCGGCGCTGTCGGCGGAAGCCATGA
ATCATCATCCCGAATGGTTCAACGTGTACAACCGGCTCACCATCGACCTGACGACGCATGATGCCGGCGGGATCACGGCA
AAAGATTTCCAACTGGCGGCTAAACTCGACGCCCTGGCAGCGGGTTAA

Upstream 100 bases:

>100_bases
GAAGGCTCCGGCGCGACCGGCTCGGCGCGTTGGAACTGTAAGTCCTGGGGAGACATGTTGGAGTATAGGCACTCTCGCGA
AAATGTGTCAATGTGAACTT

Downstream 100 bases:

>100_bases
AGCTCGCCGGTTTTCAGTTCGTATTTGGCTTTGAGCGCGGTCAACGCGTTTCCCACATCATCGTTCGGTATCGCGTAGCG
CTCGAGCATTGCTTCCAATT

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MTTKLSESEIQSALRERSAWTVVNGKLHREYKFADFIHAFGFMTCAALSAEAMNHHPEWFNVYNRLTIDLTTHDAGGITA
KDFQLAAKLDALAAG

Sequences:

>Translated_95_residues
MTTKLSESEIQSALRERSAWTVVNGKLHREYKFADFIHAFGFMTCAALSAEAMNHHPEWFNVYNRLTIDLTTHDAGGITA
KDFQLAAKLDALAAG
>Mature_94_residues
TTKLSESEIQSALRERSAWTVVNGKLHREYKFADFIHAFGFMTCAALSAEAMNHHPEWFNVYNRLTIDLTTHDAGGITAK
DFQLAAKLDALAAG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=83, Percent_Identity=50.6024096385542, Blast_Score=86, Evalue=4e-18,
Organism=Homo sapiens, GI4557831, Length=78, Percent_Identity=43.5897435897436, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533705, Length=93, Percent_Identity=45.1612903225806, Blast_Score=91, Evalue=9e-20,
Organism=Drosophila melanogaster, GI45549100, Length=97, Percent_Identity=41.2371134020619, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_SOLUE (Q01VX3)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826477.1
- ProteinModelPortal:   Q01VX3
- SMR:   Q01VX3
- STRING:   Q01VX3
- GeneID:   4426569
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_5239
- NMPDR:   fig|234267.9.peg.4969
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   HAFGFMT
- ProtClustDB:   PRK00823
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 10572; Mature: 10441

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKLSESEIQSALRERSAWTVVNGKLHREYKFADFIHAFGFMTCAALSAEAMNHHPEWF
CCCCCCHHHHHHHHHHCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NVYNRLTIDLTTHDAGGITAKDFQLAAKLDALAAG
HHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTKLSESEIQSALRERSAWTVVNGKLHREYKFADFIHAFGFMTCAALSAEAMNHHPEWF
CCCCCHHHHHHHHHHCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NVYNRLTIDLTTHDAGGITAKDFQLAAKLDALAAG
HHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA