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The map label for this gene is hup [H]

Identifier: 116624250

GI number: 116624250

Start: 6492509

End: 6492835

Strand: Direct

Name: hup [H]

Synonym: Acid_5168

Alternate gene names: 116624250

Gene position: 6492509-6492835 (Clockwise)

Preceding gene: 116624246

Following gene: 116624251

Centisome position: 65.15

GC content: 55.66

Gene sequence:

>327_bases
ATGTGGTTGACTGATGCGGGAACCAGGATCGTTCCGCCGCTGGACCAGGAGGCTGTTTTGATCAAGCTGGATATCATTAA
CGAAGTAGTGAATCGAACCGGCATCACCAAGACCAAAGCTGAAATGGCAGTCGAAACCGTCTTCGAGTCCATGAAGAAGG
CGCTCGAACAGGGCGACCGCATCGAATTGCGCGGCTTTGGAGTCTTTAACGTTAAGCCGCGTAAAACGGGAATCGGACGC
AATCCGCGCACCGGCGCGGAGGTTTCCATTCCTCCCGGAAAGGCCGTGCGCTTCAAGCCCGGCAAGGAGTTACAGACGCT
GCAGTAG

Upstream 100 bases:

>100_bases
CACCCGTGGCAAAACGCCCGCAGGCGCGGCGAAATTCCTCGCTGGTCACCGGCCTGTGCCGGTCCGTCTCGCTTGACATG
GGAATAAATTCAATCTTATC

Downstream 100 bases:

>100_bases
ATCGCTGCGCGCTCGAAGTCCATCGTGTCTTCCCAGGATTTTTCTCCTGCGCCGTTCCCGGATTATCCGGAAACCGGGAC
CAGCGAGTCTTATTCCGTTC

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 108; Mature: 108

Protein sequence:

>108_residues
MWLTDAGTRIVPPLDQEAVLIKLDIINEVVNRTGITKTKAEMAVETVFESMKKALEQGDRIELRGFGVFNVKPRKTGIGR
NPRTGAEVSIPPGKAVRFKPGKELQTLQ

Sequences:

>Translated_108_residues
MWLTDAGTRIVPPLDQEAVLIKLDIINEVVNRTGITKTKAEMAVETVFESMKKALEQGDRIELRGFGVFNVKPRKTGIGR
NPRTGAEVSIPPGKAVRFKPGKELQTLQ
>Mature_108_residues
MWLTDAGTRIVPPLDQEAVLIKLDIINEVVNRTGITKTKAEMAVETVFESMKKALEQGDRIELRGFGVFNVKPRKTGIGR
NPRTGAEVSIPPGKAVRFKPGKELQTLQ

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=88, Percent_Identity=34.0909090909091, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI1786644, Length=84, Percent_Identity=36.9047619047619, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=39.0804597701149, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1790433, Length=84, Percent_Identity=34.5238095238095, Blast_Score=62, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 11943; Mature: 11943

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLTDAGTRIVPPLDQEAVLIKLDIINEVVNRTGITKTKAEMAVETVFESMKKALEQGDR
CCCCCCCCEECCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCE
IELRGFGVFNVKPRKTGIGRNPRTGAEVSIPPGKAVRFKPGKELQTLQ
EEEEECCEEECCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MWLTDAGTRIVPPLDQEAVLIKLDIINEVVNRTGITKTKAEMAVETVFESMKKALEQGDR
CCCCCCCCEECCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCE
IELRGFGVFNVKPRKTGIGRNPRTGAEVSIPPGKAVRFKPGKELQTLQ
EEEEECCEEECCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]