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The map label for this gene is secY [H]

Identifier: 116624182

GI number: 116624182

Start: 6431247

End: 6432638

Strand: Reverse

Name: secY [H]

Synonym: Acid_5098

Alternate gene names: 116624182

Gene position: 6432638-6431247 (Counterclockwise)

Preceding gene: 116624183

Following gene: 116624181

Centisome position: 64.55

GC content: 57.83

Gene sequence:

>1392_bases
ATGAACAAGCTACTAGAAGCCTTCGCGAACATTTTTCGCGTACCGGACCTCCGCAAACGGCTCATGTTCACTCTGGGTCT
GCTCGCGGTCTATCGTCTGGGCGGCCACATCCCCACGCCGGGTATCAACATCCAGCGCTGGGAAGAGTTTTTCAGCTCGA
ATGCCGGATCGATCTTTGGCTTCTTCGACCTTTTCGCCGGTGGCAACATCAAGCGCCTGACGGTCTTCGCCCTCGGCATC
ATGCCGTACATCACTGCGTCGATCATCTTGCAGTTGCTGACGGTGGTGGTGCCGACGCTCGAGAAATTGCAGAAGGAAGG
CGAACTGGGGCGTCGCAAGATCACCCAGTGGACCCGCTACCTGACGATCATCCTTTCGATTCTGCAATCCTTCGGGATCT
CGCAGGGCCTGATGGGCATGCAGCAGGGCATCGTGATCAACCCGGGCATTGGGTTCGTATTCCTGACGATTCTCTCCCTG
ACCACAGGTACGGCGTTCATTATGTGGCTGGGCGAGCAGATCTCCGAGCGCGGCGTCGGCAACGGGATGTCGCTGATCAT
TTTCACCGGCATCGTGGTGGGCCTGCCGAACGCGATCGCAAACATCTACCAGCACGTGTTCACGATTCACGATTGGGGCG
CAATCACCCTGATCGTCCTGATGGCGCTGATGGTGGCGGTAGTCGCTTTCATCGTCCTGGTGGAGCGCGGCGAGCGCCGG
ATTCCGGTGCAGTACGCCAAGCGCGTGGTGGGACGGCGCGTGATGGGCGGGCAATCGACGCATATGCCGCTGAAGGTCAA
CGCGGGCGGCGTGATCCCAGTAATCTTCGCCTCTTCGATTCTGGCCTTTCCGCAGACACTGGCGCAGTTCGGCTGGGTGA
AAAACCTGCCGTGGTTGAGCAAGACCCTGGCGACGATCCAGCACGGCGAACCGATGTACTACGTGCTCTTCGTGGCCGGC
ATCATCTTCTTCTGTTTCTTCTACGTTTCGATTATCTTTAATCCGAACGAGGCAGCCGACAATATGCGCAAATACGGCGG
CTTCATCCCGGGCATTCGTCCGGGCCGGAACACGGCGGATTACATGAACAACATCCTCACCAAGATCACGGTGGTGGGTG
GTATTTACCTGGCGATCCTGTGCCTGATTCCGGACATCATGATTTCGGGCATCAAACTTCACCACTTATGGCTGGTGGGG
GATTGGATCGACCGTGTCGCCCCGCGCTTCATACTGGAAGGGCTGGGAGTGAACTTTTATTTCGGCGGCACATCTCTGTT
GATTGTCGTCGGCGTTGCCATGGATACGATCAACCAGATCGAAGCCCAGCTCATTATGCGGCATTACGAAGGATTCACGC
CGCGCTCGGGCCGTATTCGTGGCCGGCGCTAG

Upstream 100 bases:

>100_bases
CATTTTTCCAAGTCGGCGCTGGAGAAGATCCAGCAGGCCGGCGGAACGGCACAGATGATCGGCGCGGAAACCAAGTAGGC
GCCGGGAATCGAAGGGTACC

Downstream 100 bases:

>100_bases
CTTGAATTTGTGAAAGCCATCGTACTGTTCGGCTCACCAGGCTCCGGAAAAGGTACCCAGGCTAAGATGTTGACGCAATG
CCTGGCGATCCCCCATATCT

Product: protein translocase subunit SecY/sec61 alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNKLLEAFANIFRVPDLRKRLMFTLGLLAVYRLGGHIPTPGINIQRWEEFFSSNAGSIFGFFDLFAGGNIKRLTVFALGI
MPYITASIILQLLTVVVPTLEKLQKEGELGRRKITQWTRYLTIILSILQSFGISQGLMGMQQGIVINPGIGFVFLTILSL
TTGTAFIMWLGEQISERGVGNGMSLIIFTGIVVGLPNAIANIYQHVFTIHDWGAITLIVLMALMVAVVAFIVLVERGERR
IPVQYAKRVVGRRVMGGQSTHMPLKVNAGGVIPVIFASSILAFPQTLAQFGWVKNLPWLSKTLATIQHGEPMYYVLFVAG
IIFFCFFYVSIIFNPNEAADNMRKYGGFIPGIRPGRNTADYMNNILTKITVVGGIYLAILCLIPDIMISGIKLHHLWLVG
DWIDRVAPRFILEGLGVNFYFGGTSLLIVVGVAMDTINQIEAQLIMRHYEGFTPRSGRIRGRR

Sequences:

>Translated_463_residues
MNKLLEAFANIFRVPDLRKRLMFTLGLLAVYRLGGHIPTPGINIQRWEEFFSSNAGSIFGFFDLFAGGNIKRLTVFALGI
MPYITASIILQLLTVVVPTLEKLQKEGELGRRKITQWTRYLTIILSILQSFGISQGLMGMQQGIVINPGIGFVFLTILSL
TTGTAFIMWLGEQISERGVGNGMSLIIFTGIVVGLPNAIANIYQHVFTIHDWGAITLIVLMALMVAVVAFIVLVERGERR
IPVQYAKRVVGRRVMGGQSTHMPLKVNAGGVIPVIFASSILAFPQTLAQFGWVKNLPWLSKTLATIQHGEPMYYVLFVAG
IIFFCFFYVSIIFNPNEAADNMRKYGGFIPGIRPGRNTADYMNNILTKITVVGGIYLAILCLIPDIMISGIKLHHLWLVG
DWIDRVAPRFILEGLGVNFYFGGTSLLIVVGVAMDTINQIEAQLIMRHYEGFTPRSGRIRGRR
>Mature_463_residues
MNKLLEAFANIFRVPDLRKRLMFTLGLLAVYRLGGHIPTPGINIQRWEEFFSSNAGSIFGFFDLFAGGNIKRLTVFALGI
MPYITASIILQLLTVVVPTLEKLQKEGELGRRKITQWTRYLTIILSILQSFGISQGLMGMQQGIVINPGIGFVFLTILSL
TTGTAFIMWLGEQISERGVGNGMSLIIFTGIVVGLPNAIANIYQHVFTIHDWGAITLIVLMALMVAVVAFIVLVERGERR
IPVQYAKRVVGRRVMGGQSTHMPLKVNAGGVIPVIFASSILAFPQTLAQFGWVKNLPWLSKTLATIQHGEPMYYVLFVAG
IIFFCFFYVSIIFNPNEAADNMRKYGGFIPGIRPGRNTADYMNNILTKITVVGGIYLAILCLIPDIMISGIKLHHLWLVG
DWIDRVAPRFILEGLGVNFYFGGTSLLIVVGVAMDTINQIEAQLIMRHYEGFTPRSGRIRGRR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=438, Percent_Identity=50, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 51475; Mature: 51475

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLEAFANIFRVPDLRKRLMFTLGLLAVYRLGGHIPTPGINIQRWEEFFSSNAGSIFG
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHH
FFDLFAGGNIKRLTVFALGIMPYITASIILQLLTVVVPTLEKLQKEGELGRRKITQWTRY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIILSILQSFGISQGLMGMQQGIVINPGIGFVFLTILSLTTGTAFIMWLGEQISERGVG
HHHHHHHHHHCCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGMSLIIFTGIVVGLPNAIANIYQHVFTIHDWGAITLIVLMALMVAVVAFIVLVERGERR
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IPVQYAKRVVGRRVMGGQSTHMPLKVNAGGVIPVIFASSILAFPQTLAQFGWVKNLPWLS
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KTLATIQHGEPMYYVLFVAGIIFFCFFYVSIIFNPNEAADNMRKYGGFIPGIRPGRNTAD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHH
YMNNILTKITVVGGIYLAILCLIPDIMISGIKLHHLWLVGDWIDRVAPRFILEGLGVNFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHHHHHHCCCEEE
FGGTSLLIVVGVAMDTINQIEAQLIMRHYEGFTPRSGRIRGRR
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKLLEAFANIFRVPDLRKRLMFTLGLLAVYRLGGHIPTPGINIQRWEEFFSSNAGSIFG
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHH
FFDLFAGGNIKRLTVFALGIMPYITASIILQLLTVVVPTLEKLQKEGELGRRKITQWTRY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIILSILQSFGISQGLMGMQQGIVINPGIGFVFLTILSLTTGTAFIMWLGEQISERGVG
HHHHHHHHHHCCCCHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGMSLIIFTGIVVGLPNAIANIYQHVFTIHDWGAITLIVLMALMVAVVAFIVLVERGERR
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IPVQYAKRVVGRRVMGGQSTHMPLKVNAGGVIPVIFASSILAFPQTLAQFGWVKNLPWLS
CCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KTLATIQHGEPMYYVLFVAGIIFFCFFYVSIIFNPNEAADNMRKYGGFIPGIRPGRNTAD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHH
YMNNILTKITVVGGIYLAILCLIPDIMISGIKLHHLWLVGDWIDRVAPRFILEGLGVNFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHHHHHHHHHCCCEEE
FGGTSLLIVVGVAMDTINQIEAQLIMRHYEGFTPRSGRIRGRR
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]