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The map label for this gene is ligC

Identifier: 116624161

GI number: 116624161

Start: 6413248

End: 6414264

Strand: Direct

Name: ligC

Synonym: Acid_5077

Alternate gene names: NA

Gene position: 6413248-6414264 (Clockwise)

Preceding gene: 116624160

Following gene: 116624162

Centisome position: 64.35

GC content: 66.18

Gene sequence:

>1017_bases
ATGACGATGGCACCCATGGAAGCACTGGCAGCGCTCGCGGTACCGGAAGGGCCGGAGTGGCAATACGAGCCGAAGTGGGA
CGGTTTCCGCTGCATCGCGTTCCGGCGCGGCGATGAGGTGAAATTGCAATCGAAATCGGGACAGCCGCTGGGGCGCTACT
TCCCGGACATCGTCGGCGCATTACAGCGCGTACGCGCGAAGGAATTCGTACTGGATGGCGAGTTGGTGATCCCTGTGGAG
GGCGATCTCTCTTTCAACGAACTGCAATTGCGCCTGCATCCGGCGGCGACCCGCGTCAACATGCTGGCGGCCAAGCATCC
GGCGCTCTACATCGTGTTCGACCTGCTGACGGGCGACTTGCCGCGGCGGCCTCTAAGCGAGCGGCGCGCGAAACTCGAGG
AGTTCGCGGCGCGGAATTTCGAAGGCATCAAAGGGCTTGGACTCTCGCCGGCCACGGGGTCGCTTCCCGACGCGCGCAAG
TGGCTGCGTACGATGGGCGGGGGCCTGGACGGCATCATCGCCAAGCGGCTGGATGCGGAGTACGAGCCCGGCGAGCGCAG
TGGCGCGGTGCAGAAAATCAAGAGCCTGCGCAGTGCGGATTGCGTGGTGGGGGGCTTCCGCTATGCGACGTCGGGCAAGG
TGGTGGGATCGCTGCTGCTCGGGCTCTACGATGACGAAGGGCTGCTGCATCACGTGGGGTACACGTCGTCGATCGCCGGC
GCGGAGAAGGCGGCGCTGACTAAGAAGCTGGAGGCGTTGCGCGAGCAGCCGGGCTTCACGGGCAGGGCGCCCGGAGCGCC
GAGCCGGTGGAGCACGGAGCGTTCCGGCGAGTTCGAGCCGCTGGCGCCGAAGCTGGTGGTAGAGGTGCAGTACGACCATT
TCACCGGCGGGCGATTTCGTCACGGCACCAAGTTCCTGCGATGGCGGCACGATAAGGCGCCCTCGCAGTGCCTCATGAGC
CAGGTGGAGCATGAAACGCGTTCGCCGCTCGGGCTGCTTGCGCCGGCCGCGGGCTGA

Upstream 100 bases:

>100_bases
ATTTTCGCATCGACAACATGGCGGAGCGCGTGCGCAAAATGGGCGACCTGTGGCATCCGCTGGTGATGCAGCGCGGGCGG
CTGAAGCTGGAGCGCGTCTC

Downstream 100 bases:

>100_bases
AGGCGCATATAATGAATCGGCGCGGCGAACTCGGTATCCTTTTGGAGAGGATACCGTGGATCGAACTTTCTACCGCCTGC
AGGGATCTGTCTTCGTCCTG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTMAPMEALAALAVPEGPEWQYEPKWDGFRCIAFRRGDEVKLQSKSGQPLGRYFPDIVGALQRVRAKEFVLDGELVIPVE
GDLSFNELQLRLHPAATRVNMLAAKHPALYIVFDLLTGDLPRRPLSERRAKLEEFAARNFEGIKGLGLSPATGSLPDARK
WLRTMGGGLDGIIAKRLDAEYEPGERSGAVQKIKSLRSADCVVGGFRYATSGKVVGSLLLGLYDDEGLLHHVGYTSSIAG
AEKAALTKKLEALREQPGFTGRAPGAPSRWSTERSGEFEPLAPKLVVEVQYDHFTGGRFRHGTKFLRWRHDKAPSQCLMS
QVEHETRSPLGLLAPAAG

Sequences:

>Translated_338_residues
MTMAPMEALAALAVPEGPEWQYEPKWDGFRCIAFRRGDEVKLQSKSGQPLGRYFPDIVGALQRVRAKEFVLDGELVIPVE
GDLSFNELQLRLHPAATRVNMLAAKHPALYIVFDLLTGDLPRRPLSERRAKLEEFAARNFEGIKGLGLSPATGSLPDARK
WLRTMGGGLDGIIAKRLDAEYEPGERSGAVQKIKSLRSADCVVGGFRYATSGKVVGSLLLGLYDDEGLLHHVGYTSSIAG
AEKAALTKKLEALREQPGFTGRAPGAPSRWSTERSGEFEPLAPKLVVEVQYDHFTGGRFRHGTKFLRWRHDKAPSQCLMS
QVEHETRSPLGLLAPAAG
>Mature_337_residues
TMAPMEALAALAVPEGPEWQYEPKWDGFRCIAFRRGDEVKLQSKSGQPLGRYFPDIVGALQRVRAKEFVLDGELVIPVEG
DLSFNELQLRLHPAATRVNMLAAKHPALYIVFDLLTGDLPRRPLSERRAKLEEFAARNFEGIKGLGLSPATGSLPDARKW
LRTMGGGLDGIIAKRLDAEYEPGERSGAVQKIKSLRSADCVVGGFRYATSGKVVGSLLLGLYDDEGLLHHVGYTSSIAGA
EKAALTKKLEALREQPGFTGRAPGAPSRWSTERSGEFEPLAPKLVVEVQYDHFTGGRFRHGTKFLRWRHDKAPSQCLMSQ
VEHETRSPLGLLAPAAG

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 37085; Mature: 36954

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMAPMEALAALAVPEGPEWQYEPKWDGFRCIAFRRGDEVKLQSKSGQPLGRYFPDIVGA
CCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHH
LQRVRAKEFVLDGELVIPVEGDLSFNELQLRLHPAATRVNMLAAKHPALYIVFDLLTGDL
HHHHHHHHEEECCCEEEEECCCCCCCEEEEEEECHHHHHHHHHHCCCEEEEEEEHHHCCC
PRRPLSERRAKLEEFAARNFEGIKGLGLSPATGSLPDARKWLRTMGGGLDGIIAKRLDAE
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCC
YEPGERSGAVQKIKSLRSADCVVGGFRYATSGKVVGSLLLGLYDDEGLLHHVGYTSSIAG
CCCCCCCHHHHHHHHHHHCCCEEECEEECCCCHHHHHHHHHHCCCCCCEECCCCCHHHCC
AEKAALTKKLEALREQPGFTGRAPGAPSRWSTERSGEFEPLAPKLVVEVQYDHFTGGRFR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
HGTKFLRWRHDKAPSQCLMSQVEHETRSPLGLLAPAAG
CCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TMAPMEALAALAVPEGPEWQYEPKWDGFRCIAFRRGDEVKLQSKSGQPLGRYFPDIVGA
CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHH
LQRVRAKEFVLDGELVIPVEGDLSFNELQLRLHPAATRVNMLAAKHPALYIVFDLLTGDL
HHHHHHHHEEECCCEEEEECCCCCCCEEEEEEECHHHHHHHHHHCCCEEEEEEEHHHCCC
PRRPLSERRAKLEEFAARNFEGIKGLGLSPATGSLPDARKWLRTMGGGLDGIIAKRLDAE
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCC
YEPGERSGAVQKIKSLRSADCVVGGFRYATSGKVVGSLLLGLYDDEGLLHHVGYTSSIAG
CCCCCCCHHHHHHHHHHHCCCEEECEEECCCCHHHHHHHHHHCCCCCCEECCCCCHHHCC
AEKAALTKKLEALREQPGFTGRAPGAPSRWSTERSGEFEPLAPKLVVEVQYDHFTGGRFR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
HGTKFLRWRHDKAPSQCLMSQVEHETRSPLGLLAPAAG
CCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]