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The map label for this gene is 116624107

Identifier: 116624107

GI number: 116624107

Start: 6338964

End: 6341036

Strand: Reverse

Name: 116624107

Synonym: Acid_5022

Alternate gene names: NA

Gene position: 6341036-6338964 (Counterclockwise)

Preceding gene: 116624109

Following gene: 116624104

Centisome position: 63.63

GC content: 61.79

Gene sequence:

>2073_bases
ATGCGCCGAATCCTCATCAGCAGTTCTCTGTTTGCCGTTCTTTCGCTGTCCGTGTTAGTTACCGTACGGTCCGCGAAATC
CGCTCCGCAGGCCAAGCCGAAGATGGCAAAATCGGAGGCGGTTGGCGCCTCCTACGGGAATGCGGAATCGATCAGCGAAA
ACGAGCTGAAGGTCTACTTGTACTTCCTGGCCTCCGATCAGCTCGAAGGCCGCAATCTCCCGTCGCGTGGTTTCGACACG
GCGGCACTCTACGTCGCCAGCCATCTGGCGGAGTGGGGGTTAAAACCGGGAGGCAGCACGTCGAACACGAACGGGCCGCT
GCAGCCTTACATGATGCCGATGGAAATGTTGAGCAAGTCGGTGTCGGTTGACGATAGCAAAGCGTCGATCACGGCGCCGG
GTGGGCGCGGCGCTCGCGGCGGCGGAGGCGCGGGTGGGGCAGGCGGTGGCGGGGGAGCGCGCGGCGGGAACGCGGCGCCG
GTCGGACCGCAGACCACGGATTTCCTCTACAGCAAGGACTGGACGGTGACTGCCGGCGGCCGCGGCGCACCGCCACTAGA
AGCATTTGACGTCACCGGCAGCATGGTCTTCGCCGGCAACGGTTACGTCATCAACAAAAGCAAGATCAATCCTTACGATG
GGTTGGACGTGAAGGGCAAGATCATCGTCATTGCCGGTCTGCCCGCCGAGATCGCGGTGCAGCAGGCGGCTCTACAGGCC
GCGGGCGGCCGCGGCGGGCGTGGGGGAGGAGCGGCGGCTCCGAGTGCCGGCGGTGCACCGGCTCCGGACCCGACGGTCAA
TCCGCTGGGAACGGCATGCACGGATTTTCTGACGCCGGAACAGTACGGGGCTCAGTATGGCGCGCTGGCGGTGGTTTCGA
TTCCCACCTTCCAGCAGTTGAGCGCGGCGGCGAATCCCAATGCGGGCTTCGGCGGTTTCGGCGGCGGTGGCGGGGGCAGG
GGCGCCGGACTCAACGGGCCGAACTATCAGGTCCCGATGCTGCAGGCGAAGCCCGCCTGCGCGAGCGTGCCGGCGGTCCA
GGCCGGGCTCACCATGACCAACGCGATTTTCCAGGGAGAAAAATCCAGCGGACAGCAAGTGTTCTACGCGGCGGGCACTA
ATGCCAAACAGGATTCCTTCGAGCTGAATGCCGAAAAGAAGTTGAAGTTGAAAGTGGCCGTCAATACCATCCAGGGACAT
GGCGAAAACGTGGTCGGCATTCTCGAGGGCGGCGACCCGGTGTTGAAGAACGAGTATGTGGTGATGAGCGCGCACCTGGA
TCACATCGGACTCGCAGCGCCGCTACCCGACGGGCATAACGTCAACAACGGCGCCGATGACGATGGTTCGGGTTCTACCG
GCCTCCTGGCCATCGCACGCGCTTATTCGGAAGGTGCCGCCAAAGGCATACGACCCAAGCGCAGCATCATCTTCTTGTGG
ATGGCCGGCGAAGAGAAGGGTTTGTGGGGCTCGCAGTATTTCAACGAGTACCCGCCGGTGGACATCACGAAAGTGGTGGC
TAATTTGAATATGGACATGATCGGGCGCACGAAGGGTCCGGGCTTCACGGATTCGGATCCCACCCATGTGCTGGTAAAGC
CGGGCGAGATTCTGGTGGTGGGTCCGAACATCTCCAGCGACGACCTGGAAAAGACCATCGAGACGGTGAACGGGGGCTAC
CAGAAGTTGGAACTGAATCACTTCTACGACGCCACTGCACCCGACGATACGCACGACAACCTGGGACCGCAACCTCGCGG
GCAGCGCATTTTCTATCGTAGCGACCACTATAACTTCGCGAAGATGGGCATTCCGATCGCGTTTTTCACCACCGGCCTGC
ACCCGGACTATCATCGCGCTACGGATACGCCCGATAAGATCGACTACAAGGAGATGCAGAGCGTCTCGAAAACCGTGGCT
GCTGTCGGTTGGGTGCTGGCGAACCAGGCCGGGCGGCCCCAGTTGAAAACCAATTTGCCCGAGCAGTTGATCAAGGATAT
GAAGTCGGCGAAGGAGCAGGGCTGGGGCAAACTGACACCGGTCATGCCTCCCATCGCGGGCATGCCGTATTGA

Upstream 100 bases:

>100_bases
GGAGGGTGGCGGAACGGCGTAGAGTATTTTGGGGCAGGGTGAAACCGGTTCCTGAGGACCAAGCCGGCGGCGCTATACTC
TGAATATCCCTGAAGGGTCT

Downstream 100 bases:

>100_bases
TGGTGAGGGGGCGGGAAGAGCGGGATGACCAGTCCCGCTCGTAGCCAGAAGTTGGAAATGAAAGCGCCCGCCCCTGCTTT
TAATTGAGGCGGGCCCGCGA

Product: peptidase M28

Products: NA

Alternate protein names: SGAP [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MRRILISSSLFAVLSLSVLVTVRSAKSAPQAKPKMAKSEAVGASYGNAESISENELKVYLYFLASDQLEGRNLPSRGFDT
AALYVASHLAEWGLKPGGSTSNTNGPLQPYMMPMEMLSKSVSVDDSKASITAPGGRGARGGGGAGGAGGGGGARGGNAAP
VGPQTTDFLYSKDWTVTAGGRGAPPLEAFDVTGSMVFAGNGYVINKSKINPYDGLDVKGKIIVIAGLPAEIAVQQAALQA
AGGRGGRGGGAAAPSAGGAPAPDPTVNPLGTACTDFLTPEQYGAQYGALAVVSIPTFQQLSAAANPNAGFGGFGGGGGGR
GAGLNGPNYQVPMLQAKPACASVPAVQAGLTMTNAIFQGEKSSGQQVFYAAGTNAKQDSFELNAEKKLKLKVAVNTIQGH
GENVVGILEGGDPVLKNEYVVMSAHLDHIGLAAPLPDGHNVNNGADDDGSGSTGLLAIARAYSEGAAKGIRPKRSIIFLW
MAGEEKGLWGSQYFNEYPPVDITKVVANLNMDMIGRTKGPGFTDSDPTHVLVKPGEILVVGPNISSDDLEKTIETVNGGY
QKLELNHFYDATAPDDTHDNLGPQPRGQRIFYRSDHYNFAKMGIPIAFFTTGLHPDYHRATDTPDKIDYKEMQSVSKTVA
AVGWVLANQAGRPQLKTNLPEQLIKDMKSAKEQGWGKLTPVMPPIAGMPY

Sequences:

>Translated_690_residues
MRRILISSSLFAVLSLSVLVTVRSAKSAPQAKPKMAKSEAVGASYGNAESISENELKVYLYFLASDQLEGRNLPSRGFDT
AALYVASHLAEWGLKPGGSTSNTNGPLQPYMMPMEMLSKSVSVDDSKASITAPGGRGARGGGGAGGAGGGGGARGGNAAP
VGPQTTDFLYSKDWTVTAGGRGAPPLEAFDVTGSMVFAGNGYVINKSKINPYDGLDVKGKIIVIAGLPAEIAVQQAALQA
AGGRGGRGGGAAAPSAGGAPAPDPTVNPLGTACTDFLTPEQYGAQYGALAVVSIPTFQQLSAAANPNAGFGGFGGGGGGR
GAGLNGPNYQVPMLQAKPACASVPAVQAGLTMTNAIFQGEKSSGQQVFYAAGTNAKQDSFELNAEKKLKLKVAVNTIQGH
GENVVGILEGGDPVLKNEYVVMSAHLDHIGLAAPLPDGHNVNNGADDDGSGSTGLLAIARAYSEGAAKGIRPKRSIIFLW
MAGEEKGLWGSQYFNEYPPVDITKVVANLNMDMIGRTKGPGFTDSDPTHVLVKPGEILVVGPNISSDDLEKTIETVNGGY
QKLELNHFYDATAPDDTHDNLGPQPRGQRIFYRSDHYNFAKMGIPIAFFTTGLHPDYHRATDTPDKIDYKEMQSVSKTVA
AVGWVLANQAGRPQLKTNLPEQLIKDMKSAKEQGWGKLTPVMPPIAGMPY
>Mature_690_residues
MRRILISSSLFAVLSLSVLVTVRSAKSAPQAKPKMAKSEAVGASYGNAESISENELKVYLYFLASDQLEGRNLPSRGFDT
AALYVASHLAEWGLKPGGSTSNTNGPLQPYMMPMEMLSKSVSVDDSKASITAPGGRGARGGGGAGGAGGGGGARGGNAAP
VGPQTTDFLYSKDWTVTAGGRGAPPLEAFDVTGSMVFAGNGYVINKSKINPYDGLDVKGKIIVIAGLPAEIAVQQAALQA
AGGRGGRGGGAAAPSAGGAPAPDPTVNPLGTACTDFLTPEQYGAQYGALAVVSIPTFQQLSAAANPNAGFGGFGGGGGGR
GAGLNGPNYQVPMLQAKPACASVPAVQAGLTMTNAIFQGEKSSGQQVFYAAGTNAKQDSFELNAEKKLKLKVAVNTIQGH
GENVVGILEGGDPVLKNEYVVMSAHLDHIGLAAPLPDGHNVNNGADDDGSGSTGLLAIARAYSEGAAKGIRPKRSIIFLW
MAGEEKGLWGSQYFNEYPPVDITKVVANLNMDMIGRTKGPGFTDSDPTHVLVKPGEILVVGPNISSDDLEKTIETVNGGY
QKLELNHFYDATAPDDTHDNLGPQPRGQRIFYRSDHYNFAKMGIPIAFFTTGLHPDYHRATDTPDKIDYKEMQSVSKTVA
AVGWVLANQAGRPQLKTNLPEQLIKDMKSAKEQGWGKLTPVMPPIAGMPY

Specific function: Specific for larger hydrophobic acids, especially leucine. No cleavage occurs if the next residue is proline [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28A subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484 [H]

Pfam domain/function: PF04389 Peptidase_M28 [H]

EC number: =3.4.11.24 [H]

Molecular weight: Translated: 71780; Mature: 71780

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILISSSLFAVLSLSVLVTVRSAKSAPQAKPKMAKSEAVGASYGNAESISENELKVYL
CCEEEECHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEE
YFLASDQLEGRNLPSRGFDTAALYVASHLAEWGLKPGGSTSNTNGPLQPYMMPMEMLSKS
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VSVDDSKASITAPGGRGARGGGGAGGAGGGGGARGGNAAPVGPQTTDFLYSKDWTVTAGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECCC
RGAPPLEAFDVTGSMVFAGNGYVINKSKINPYDGLDVKGKIIVIAGLPAEIAVQQAALQA
CCCCCCEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
AGGRGGRGGGAAAPSAGGAPAPDPTVNPLGTACTDFLTPEQYGAQYGALAVVSIPTFQQL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCCCEEEEECCCHHHH
SAAANPNAGFGGFGGGGGGRGAGLNGPNYQVPMLQAKPACASVPAVQAGLTMTNAIFQGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHCCCHHHHCCHHHHHHHCCC
KSSGQQVFYAAGTNAKQDSFELNAEKKLKLKVAVNTIQGHGENVVGILEGGDPVLKNEYV
CCCCCEEEEEECCCCCCCCEECCCCCEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
VMSAHLDHIGLAAPLPDGHNVNNGADDDGSGSTGLLAIARAYSEGAAKGIRPKRSIIFLW
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
MAGEEKGLWGSQYFNEYPPVDITKVVANLNMDMIGRTKGPGFTDSDPTHVLVKPGEILVV
EECCCCCCCHHHHHCCCCCCHHHHHHHHCCHHEEECCCCCCCCCCCCCEEEECCCEEEEE
GPNISSDDLEKTIETVNGGYQKLELNHFYDATAPDDTHDNLGPQPRGQRIFYRSDHYNFA
CCCCCHHHHHHHHHHHCCCEEEEEEEHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCH
KMGIPIAFFTTGLHPDYHRATDTPDKIDYKEMQSVSKTVAAVGWVLANQAGRPQLKTNLP
HHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCH
EQLIKDMKSAKEQGWGKLTPVMPPIAGMPY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRILISSSLFAVLSLSVLVTVRSAKSAPQAKPKMAKSEAVGASYGNAESISENELKVYL
CCEEEECHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEE
YFLASDQLEGRNLPSRGFDTAALYVASHLAEWGLKPGGSTSNTNGPLQPYMMPMEMLSKS
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VSVDDSKASITAPGGRGARGGGGAGGAGGGGGARGGNAAPVGPQTTDFLYSKDWTVTAGG
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECCC
RGAPPLEAFDVTGSMVFAGNGYVINKSKINPYDGLDVKGKIIVIAGLPAEIAVQQAALQA
CCCCCCEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
AGGRGGRGGGAAAPSAGGAPAPDPTVNPLGTACTDFLTPEQYGAQYGALAVVSIPTFQQL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCCCEEEEECCCHHHH
SAAANPNAGFGGFGGGGGGRGAGLNGPNYQVPMLQAKPACASVPAVQAGLTMTNAIFQGE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHCCCHHHHCCHHHHHHHCCC
KSSGQQVFYAAGTNAKQDSFELNAEKKLKLKVAVNTIQGHGENVVGILEGGDPVLKNEYV
CCCCCEEEEEECCCCCCCCEECCCCCEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
VMSAHLDHIGLAAPLPDGHNVNNGADDDGSGSTGLLAIARAYSEGAAKGIRPKRSIIFLW
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
MAGEEKGLWGSQYFNEYPPVDITKVVANLNMDMIGRTKGPGFTDSDPTHVLVKPGEILVV
EECCCCCCCHHHHHCCCCCCHHHHHHHHCCHHEEECCCCCCCCCCCCCEEEECCCEEEEE
GPNISSDDLEKTIETVNGGYQKLELNHFYDATAPDDTHDNLGPQPRGQRIFYRSDHYNFA
CCCCCHHHHHHHHHHHCCCEEEEEEEHEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCH
KMGIPIAFFTTGLHPDYHRATDTPDKIDYKEMQSVSKTVAAVGWVLANQAGRPQLKTNLP
HHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCH
EQLIKDMKSAKEQGWGKLTPVMPPIAGMPY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8665903; 2503378; 8444149; 9048953 [H]