Click here to switch to the map view.

The map label for this gene is flp [H]

Identifier: 116624086

GI number: 116624086

Start: 6306819

End: 6308606

Strand: Direct

Name: flp [H]

Synonym: Acid_5000

Alternate gene names: 116624086

Gene position: 6306819-6308606 (Clockwise)

Preceding gene: 116624084

Following gene: 116624089

Centisome position: 63.29

GC content: 63.26

Gene sequence:

>1788_bases
ATGCGCCTTGCATATCTCGCAGCCCTGCTCGCCCCCTTATGCGCCGCCCAAACCGGCACGCCCGTACCCGCACTCTCCGC
GTTGGATAACGTGATGCAGCAGGCCCTCTCCCGCTACAGCGTCAAAGGCGGTTCACTCGCAGTCGTCAAGGATGGCCGCC
TGATCTTTGCCCGCGCCTATGGCTGGGCCGATGCCGAACTCCGAATGCCCGCCCAGCCCGACTCCCTGTTCCGCTGGGCC
AGCACCAGCAAAACCCTGACCGCCGCGGCAGTGATATCCCTCGTTGACCAGGGCAAGCTCGATCTCGACACCCCGATCTT
CACTATCCTCAATCAGTATTCCCCGTATAACGGCAAATTGGGCGATGCCCATCTGGCCGCGATCACGGTTCGCCAAGTCC
TCCATCACACCGGCGGCTGGGATCGCATGATCAGCGGCGACCCGGTCACGGGCGACCGCACCATCACCGCTGCCAGCGCA
ACCCGCACCGCATTCCCGCCATCCCGCGACAACGTGATTCGTTACATGCTCGCCCAGCCTCTCGAATTCGCGCCGGGCGC
GCGCTTCGCCTATTCCAATTTCGGCTACATGCTCCTCGGACGCGTCATCGAGAAGATCAGCGGTAAATCCTACGAAGCCT
ACGTTCGCGATTCCATCCTCACCCCCTCGGGCCTCCCACGCATTCAACTCGGCGGGTCCACGCTGGCCGCCCGTTTGCCC
GGCGAAGTCAAGTATTACGATTACCCCGGTGCCCCTCTGGTCAGTTCCTACGTCTCGGCGGCGCGCGAAATGGAACCCGC
GCCCTATGGCTTCGCCAATTTCGATCTCAACGACGCCGATGGCGCATGGGTCGGTTCCGTGATCGATCTTGCCAAGTTCA
GCGCCCTGCTCGATGGCGCCCGTCCGCGCGCCCTTGTTACCGCCGAAAGTTTCGCCGCCATGATCGCCCAAACCCCACGC
ACCACCTGGGTCGATTCCGTCGGCTGGTACGGCTTCGGCCTCTTCGCTGTCCCTCAGTTAGGCGGCATCACGTGGTCCCA
CGGAGGCACCGTCCCCGGTACGCGCGCCGGCTTCTGGCACTTCGCCAACGGCATCTGTTACGCGTTCCTCTTCAACGGCG
ATAGCAAAGATCAGACCAGCCTCACCAGTTATGTTGCGCAGTCCGTCTGGGACGCGCTCGCCGCCGTGACCGATTTGCCT
GACCAAGACCTTTTCCCGCAATACTATCCCCCTACCACTGCGCCGGCCGGGGTGGTCAACGCCGCATCGTTCCTGGCCGG
CCCCGTAGCTCCCGCATCGTTGATCACCGTATTCGGCGCCGATCTCGAAGGTCCCGTCACGCTCTCGCTCGGCGATCGCA
CCATGCCCATCTTCTACAGCAGTCCCGGCCAAATCAACAGCGTTGTCCCCGCTGAAGCCCAGACCGGCGACGCCGATCTC
ATCGTTCGCAGAGAGGGATGGCCTGACGCGATATCTCCCATTACGATCGCCCCCGTGTCCCCCGCCCTCTTCGCGCTGAA
ATACCAGCCAATCGTCTTCGGTCCCGCGGAGGAAGACGCGTACCTCACCCTCTACGCCACCGGAGTCCGCGGCCATCGAA
CACCCGTGACCGTGAACTTCGGCGACCTGCCCGTCCCTGCCGACTACGCCGGCCCGCAACTGCAATTCGAAGGCCTGGAC
CAAATCAACGTCAAGCTCCCGCGAACCCTCGCCGCAAAAGGCGATGTCTTCGTCACCCTGACCGTCGATACCCAACGCAC
CAACTCCGTTCTCGTCAGTTTCCCCTAG

Upstream 100 bases:

>100_bases
CATATCGTTCCCGATTATCGCAGGATGCGTCACTAGAAAGACGAACCCGCGCCACCGTTTGTTCCCGGAGTTAAAATAAG
ACTCGTAAGTCTTCTTTGCC

Downstream 100 bases:

>100_bases
TCTGTTCCTCTATCCCAGACCCACGCGATGCAGCTTCATCAGGTTCGTCGTTCCGGGCCGCCCCACCGGCTGACCTGCGA
CAAACACCACCAGCTGCCCC

Product: beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRLAYLAALLAPLCAAQTGTPVPALSALDNVMQQALSRYSVKGGSLAVVKDGRLIFARAYGWADAELRMPAQPDSLFRWA
STSKTLTAAAVISLVDQGKLDLDTPIFTILNQYSPYNGKLGDAHLAAITVRQVLHHTGGWDRMISGDPVTGDRTITAASA
TRTAFPPSRDNVIRYMLAQPLEFAPGARFAYSNFGYMLLGRVIEKISGKSYEAYVRDSILTPSGLPRIQLGGSTLAARLP
GEVKYYDYPGAPLVSSYVSAAREMEPAPYGFANFDLNDADGAWVGSVIDLAKFSALLDGARPRALVTAESFAAMIAQTPR
TTWVDSVGWYGFGLFAVPQLGGITWSHGGTVPGTRAGFWHFANGICYAFLFNGDSKDQTSLTSYVAQSVWDALAAVTDLP
DQDLFPQYYPPTTAPAGVVNAASFLAGPVAPASLITVFGADLEGPVTLSLGDRTMPIFYSSPGQINSVVPAEAQTGDADL
IVRREGWPDAISPITIAPVSPALFALKYQPIVFGPAEEDAYLTLYATGVRGHRTPVTVNFGDLPVPADYAGPQLQFEGLD
QINVKLPRTLAAKGDVFVTLTVDTQRTNSVLVSFP

Sequences:

>Translated_595_residues
MRLAYLAALLAPLCAAQTGTPVPALSALDNVMQQALSRYSVKGGSLAVVKDGRLIFARAYGWADAELRMPAQPDSLFRWA
STSKTLTAAAVISLVDQGKLDLDTPIFTILNQYSPYNGKLGDAHLAAITVRQVLHHTGGWDRMISGDPVTGDRTITAASA
TRTAFPPSRDNVIRYMLAQPLEFAPGARFAYSNFGYMLLGRVIEKISGKSYEAYVRDSILTPSGLPRIQLGGSTLAARLP
GEVKYYDYPGAPLVSSYVSAAREMEPAPYGFANFDLNDADGAWVGSVIDLAKFSALLDGARPRALVTAESFAAMIAQTPR
TTWVDSVGWYGFGLFAVPQLGGITWSHGGTVPGTRAGFWHFANGICYAFLFNGDSKDQTSLTSYVAQSVWDALAAVTDLP
DQDLFPQYYPPTTAPAGVVNAASFLAGPVAPASLITVFGADLEGPVTLSLGDRTMPIFYSSPGQINSVVPAEAQTGDADL
IVRREGWPDAISPITIAPVSPALFALKYQPIVFGPAEEDAYLTLYATGVRGHRTPVTVNFGDLPVPADYAGPQLQFEGLD
QINVKLPRTLAAKGDVFVTLTVDTQRTNSVLVSFP
>Mature_595_residues
MRLAYLAALLAPLCAAQTGTPVPALSALDNVMQQALSRYSVKGGSLAVVKDGRLIFARAYGWADAELRMPAQPDSLFRWA
STSKTLTAAAVISLVDQGKLDLDTPIFTILNQYSPYNGKLGDAHLAAITVRQVLHHTGGWDRMISGDPVTGDRTITAASA
TRTAFPPSRDNVIRYMLAQPLEFAPGARFAYSNFGYMLLGRVIEKISGKSYEAYVRDSILTPSGLPRIQLGGSTLAARLP
GEVKYYDYPGAPLVSSYVSAAREMEPAPYGFANFDLNDADGAWVGSVIDLAKFSALLDGARPRALVTAESFAAMIAQTPR
TTWVDSVGWYGFGLFAVPQLGGITWSHGGTVPGTRAGFWHFANGICYAFLFNGDSKDQTSLTSYVAQSVWDALAAVTDLP
DQDLFPQYYPPTTAPAGVVNAASFLAGPVAPASLITVFGADLEGPVTLSLGDRTMPIFYSSPGQINSVVPAEAQTGDADL
IVRREGWPDAISPITIAPVSPALFALKYQPIVFGPAEEDAYLTLYATGVRGHRTPVTVNFGDLPVPADYAGPQLQFEGLD
QINVKLPRTLAAKGDVFVTLTVDTQRTNSVLVSFP

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=191, Percent_Identity=27.7486910994764, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786574, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17550934, Length=387, Percent_Identity=30.4909560723514, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17565630, Length=374, Percent_Identity=27.807486631016, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533026, Length=357, Percent_Identity=26.6106442577031, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 63538; Mature: 63538

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAYLAALLAPLCAAQTGTPVPALSALDNVMQQALSRYSVKGGSLAVVKDGRLIFARAY
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEC
GWADAELRMPAQPDSLFRWASTSKTLTAAAVISLVDQGKLDLDTPIFTILNQYSPYNGKL
CCCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC
GDAHLAAITVRQVLHHTGGWDRMISGDPVTGDRTITAASATRTAFPPSRDNVIRYMLAQP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC
LEFAPGARFAYSNFGYMLLGRVIEKISGKSYEAYVRDSILTPSGLPRIQLGGSTLAARLP
CCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCEEEECCCEEEEECC
GEVKYYDYPGAPLVSSYVSAAREMEPAPYGFANFDLNDADGAWVGSVIDLAKFSALLDGA
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
RPRALVTAESFAAMIAQTPRTTWVDSVGWYGFGLFAVPQLGGITWSHGGTVPGTRAGFWH
CCCEEEEHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCHHH
FANGICYAFLFNGDSKDQTSLTSYVAQSVWDALAAVTDLPDQDLFPQYYPPTTAPAGVVN
HHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
AASFLAGPVAPASLITVFGADLEGPVTLSLGDRTMPIFYSSPGQINSVVPAEAQTGDADL
HHHHHHCCCCHHHHHHEECCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCEE
IVRREGWPDAISPITIAPVSPALFALKYQPIVFGPAEEDAYLTLYATGVRGHRTPVTVNF
EEEECCCCCCCCCEEEECCCCEEEEEEECCEEECCCCCCCEEEEEEECCCCCCCEEEEEC
GDLPVPADYAGPQLQFEGLDQINVKLPRTLAAKGDVFVTLTVDTQRTNSVLVSFP
CCCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCEEEEEEEECCCCCEEEEECC
>Mature Secondary Structure
MRLAYLAALLAPLCAAQTGTPVPALSALDNVMQQALSRYSVKGGSLAVVKDGRLIFARAY
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEC
GWADAELRMPAQPDSLFRWASTSKTLTAAAVISLVDQGKLDLDTPIFTILNQYSPYNGKL
CCCCCEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC
GDAHLAAITVRQVLHHTGGWDRMISGDPVTGDRTITAASATRTAFPPSRDNVIRYMLAQP
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCC
LEFAPGARFAYSNFGYMLLGRVIEKISGKSYEAYVRDSILTPSGLPRIQLGGSTLAARLP
CCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCEEEECCCEEEEECC
GEVKYYDYPGAPLVSSYVSAAREMEPAPYGFANFDLNDADGAWVGSVIDLAKFSALLDGA
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
RPRALVTAESFAAMIAQTPRTTWVDSVGWYGFGLFAVPQLGGITWSHGGTVPGTRAGFWH
CCCEEEEHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCHHH
FANGICYAFLFNGDSKDQTSLTSYVAQSVWDALAAVTDLPDQDLFPQYYPPTTAPAGVVN
HHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHH
AASFLAGPVAPASLITVFGADLEGPVTLSLGDRTMPIFYSSPGQINSVVPAEAQTGDADL
HHHHHHCCCCHHHHHHEECCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCEE
IVRREGWPDAISPITIAPVSPALFALKYQPIVFGPAEEDAYLTLYATGVRGHRTPVTVNF
EEEECCCCCCCCCEEEECCCCEEEEEEECCEEECCCCCCCEEEEEEECCCCCCCEEEEEC
GDLPVPADYAGPQLQFEGLDQINVKLPRTLAAKGDVFVTLTVDTQRTNSVLVSFP
CCCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCEEEEEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA