| Definition | Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome. |
|---|---|
| Accession | NC_008536 |
| Length | 9,965,640 |
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The map label for this gene is gno [H]
Identifier: 116624055
GI number: 116624055
Start: 6276271
End: 6277044
Strand: Reverse
Name: gno [H]
Synonym: Acid_4969
Alternate gene names: 116624055
Gene position: 6277044-6276271 (Counterclockwise)
Preceding gene: 116624065
Following gene: 116624054
Centisome position: 62.99
GC content: 62.79
Gene sequence:
>774_bases ATGAACACACCAGAGCTCTTCTCACTCAAAAATCGTGTCGCTGTCGTGCTGGGCGGCACCAGCGGCATCGGACTCGCCAT CGCCCGCGGATTTGCCCAGGCTGGAGCCATCACCATCGCGAGCAGCCGCGATCAGGCGAAGGTCGATTCCACCGCTGCCG AACTCGAAGCTCTCGGCGCCCGCACTCTCCGCCTCACGAGTGACGTCCAGGATCGCGCAAGTCTCCAACGCCTCTGCGAC GAAACCGTGCTCGCCTATGGGCAGGTCGATGTTCTCATGGTCACCTCCGGAGCGCTCAAGAAAGCGCCCAGCGCCGAGCT CACGGACGAGGATTGGGAGCGCGTGGTCGATATCAATCTCAACGGCTCTTTCCGCGCCAACCAGGTCTTCGGCCGCCAGA TGCTCAAGCAGAAACGTGGCTCCATCATCAATACCTGCTCGATGACGACCTTCGTGAGCTTTGGTGAAGTCGCCGTCTAT TCGGCCAGCAAGGCCGGCGTCAATATGCTCACCAAAAGCCTGGCCTGCGAATGGGCCACGCAGGGCGTCCGCGTGAACGC GATCGCGCCCGGTGTTTTCCGCACCCCGCTCAATACCAACGCCCTCGACATACCGGAGCGCATGGCCGCCATCATCGGGC GCACTCCCATGGGCCGCGTGGGTCACGTCGATGAATTGGTCGGCTGCGCCATTTTCCTCGCCAGCGACGCATCGAGCTTC GTGACCGGCCAGACGATCCCGGTGGACGGCGGCTTCCTCGCAAAGGGCATCTAG
Upstream 100 bases:
>100_bases ACGAATCAACAACCCGTCCACGATCACGGCCGGCTCGGTTCTAGACTCCAGCTGCAAAGTAAGGAAGCGCATATCTCGTT GTATATTGAGTGTAAACCCA
Downstream 100 bases:
>100_bases CCCGGCTAGACTGGGGGAATGGTGCGGCTTCTTATTCTTCTCGCCCTTCTGCTCCCGGTCCACGCCACCGCCGGCACAGC TGCCGACACCGCCCGCGCGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 257; Mature: 257
Protein sequence:
>257_residues MNTPELFSLKNRVAVVLGGTSGIGLAIARGFAQAGAITIASSRDQAKVDSTAAELEALGARTLRLTSDVQDRASLQRLCD ETVLAYGQVDVLMVTSGALKKAPSAELTDEDWERVVDINLNGSFRANQVFGRQMLKQKRGSIINTCSMTTFVSFGEVAVY SASKAGVNMLTKSLACEWATQGVRVNAIAPGVFRTPLNTNALDIPERMAAIIGRTPMGRVGHVDELVGCAIFLASDASSF VTGQTIPVDGGFLAKGI
Sequences:
>Translated_257_residues MNTPELFSLKNRVAVVLGGTSGIGLAIARGFAQAGAITIASSRDQAKVDSTAAELEALGARTLRLTSDVQDRASLQRLCD ETVLAYGQVDVLMVTSGALKKAPSAELTDEDWERVVDINLNGSFRANQVFGRQMLKQKRGSIINTCSMTTFVSFGEVAVY SASKAGVNMLTKSLACEWATQGVRVNAIAPGVFRTPLNTNALDIPERMAAIIGRTPMGRVGHVDELVGCAIFLASDASSF VTGQTIPVDGGFLAKGI >Mature_257_residues MNTPELFSLKNRVAVVLGGTSGIGLAIARGFAQAGAITIASSRDQAKVDSTAAELEALGARTLRLTSDVQDRASLQRLCD ETVLAYGQVDVLMVTSGALKKAPSAELTDEDWERVVDINLNGSFRANQVFGRQMLKQKRGSIINTCSMTTFVSFGEVAVY SASKAGVNMLTKSLACEWATQGVRVNAIAPGVFRTPLNTNALDIPERMAAIIGRTPMGRVGHVDELVGCAIFLASDASSF VTGQTIPVDGGFLAKGI
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=32.2709163346614, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=30.952380952381, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.8367346938775, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=30.2788844621514, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI4503301, Length=222, Percent_Identity=31.5315315315315, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=30.327868852459, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=28.6274509803922, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI66933014, Length=234, Percent_Identity=30.3418803418803, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=28.7449392712551, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=29.7520661157025, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=32.8042328042328, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=31.6602316602317, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=29.8245614035088, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=30, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.3186813186813, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=29.6153846153846, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=26.5, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=38.6454183266932, Blast_Score=161, Evalue=4e-41, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=31.3253012048193, Blast_Score=144, Evalue=4e-36, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=34.6774193548387, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=31.2252964426877, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=30.8943089430894, Blast_Score=124, Evalue=7e-30, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=33.4661354581673, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=31.7073170731707, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=28.8065843621399, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=30.0395256916996, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.6821705426357, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=29.2817679558011, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=26.3779527559055, Blast_Score=71, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=36.0323886639676, Blast_Score=134, Evalue=5e-32, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=37.6518218623482, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=29.6, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=28.7937743190661, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=31.6205533596838, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=31.4176245210728, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.0813008130081, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=33.4645669291339, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.5471698113208, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.5151515151515, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.0676691729323, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=29.296875, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=27.3764258555133, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=25.390625, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=29.5019157088123, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17538480, Length=258, Percent_Identity=26.3565891472868, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=27.2373540856031, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=27.6515151515151, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562990, Length=253, Percent_Identity=28.4584980237154, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=28.4090909090909, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=28.0155642023346, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=26.953125, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=27.6264591439689, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=25.3846153846154, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=25.2873563218391, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=27.1653543307087, Blast_Score=73, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=26.4591439688716, Blast_Score=88, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6322861, Length=262, Percent_Identity=26.7175572519084, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322067, Length=232, Percent_Identity=26.7241379310345, Blast_Score=66, Evalue=7e-12, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=4e-33, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.9317269076305, Blast_Score=131, Evalue=6e-31, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.5381526104418, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.1285140562249, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=33.0612244897959, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=31.0204081632653, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644337, Length=229, Percent_Identity=29.6943231441048, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=29.7297297297297, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=31.2169312169312, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI21357673, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24641232, Length=212, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27113; Mature: 27113
Theoretical pI: Translated: 7.93; Mature: 7.93
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTPELFSLKNRVAVVLGGTSGIGLAIARGFAQAGAITIASSRDQAKVDSTAAELEALGA CCCCHHEECCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCC RTLRLTSDVQDRASLQRLCDETVLAYGQVDVLMVTSGALKKAPSAELTDEDWERVVDINL CEEEEHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC NGSFRANQVFGRQMLKQKRGSIINTCSMTTFVSFGEVAVYSASKAGVNMLTKSLACEWAT CCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH QGVRVNAIAPGVFRTPLNTNALDIPERMAAIIGRTPMGRVGHVDELVGCAIFLASDASSF CCEEEEEECCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHH VTGQTIPVDGGFLAKGI CCCCEEECCCCCCCCCC >Mature Secondary Structure MNTPELFSLKNRVAVVLGGTSGIGLAIARGFAQAGAITIASSRDQAKVDSTAAELEALGA CCCCHHEECCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCC RTLRLTSDVQDRASLQRLCDETVLAYGQVDVLMVTSGALKKAPSAELTDEDWERVVDINL CEEEEHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC NGSFRANQVFGRQMLKQKRGSIINTCSMTTFVSFGEVAVYSASKAGVNMLTKSLACEWAT CCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH QGVRVNAIAPGVFRTPLNTNALDIPERMAAIIGRTPMGRVGHVDELVGCAIFLASDASSF CCEEEEEECCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHH VTGQTIPVDGGFLAKGI CCCCEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]