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The map label for this gene is acyII [H]

Identifier: 116624024

GI number: 116624024

Start: 6230685

End: 6232910

Strand: Direct

Name: acyII [H]

Synonym: Acid_4936

Alternate gene names: 116624024

Gene position: 6230685-6232910 (Clockwise)

Preceding gene: 116624019

Following gene: 116624025

Centisome position: 62.52

GC content: 62.71

Gene sequence:

>2226_bases
ATGTCTCGCAACCTGGTAGCGCACGCCGTCAAGTATGTGAATTATGCGATCGCCTTCGCGCTGATCATCGCGGCCATCGC
GGTGTATTGGTATGTCTGGCGACCTTTGCCGCAGCGCTCGGGCTCCATCGACGCTGCTCTCTCGGCCCCCGCCACCGTCG
AGTTCGGCGCTCACGGCGAACCACACATTCGCGCTGCCAGCCTCGACGACGCATTTTTTCTCCAAGGGTATGTCACCGCA
CAAGACCGTCTCTTCCAGATGGACGCCCTGCGCCGCTTCGCCGGCGGGACTCTCGCCGAAGTATTCGGACCTTCGCTGGT
CGAAAGCGATCGCGAAGCCCGCAAACTCCGTATGCGGCGCATCGCCGAAGACGCCTATGGCCGCCTTCCGGACGCCGACC
GCGCCGCCTTCGCAGCCTATACGCGCGGCGTCAATCAATTCATCGCCACCCACCTGAACAACCTGCCCGTGGAGTTCACC
CTGCTCCGCTACCAGCCACGCCCCTGGAGCACGGTGGATTGTCTGCTGCTCTGCCTTCATATGTATCGCAACCTCACCAC
CACATGGAAGGACGAAATCATCAAGAACAACATGCTCGCCCAGGGAGACCGCGCCAAGGTGGAATTCCTCTTCCCCATGC
GCGGACTGGTGGATGGCAACCCCGGCTCCAACGCCTGGGTTCTCTCAGGGAAACATACGGCCTCGGGCAAGCCGCTGCTC
TCTAACGACATGCACCTGGAGTATTCCCTGCCCGGCATCTGGTACATGATCTACCTCGACGCTCCCGGCCTCCGCGTCGG
CGGTGTTTCGCTGCCCGGCGCGCCCGGTGTCATCGTCGGCCACAATGAGCGCATCGCATGGGGCATCACCAATCTCCACT
TCGACGTGCAGGATCTCTACATCGAGAAGTTCGATGACCGCACCGGCCGCTATCTCTTCCGCGGACAGGCGGAGCAGGCG
CGCGCCGAACGCGAGATCATCCGCGTCAAGGACAGACCGGCCGTCGAGGTGGATACCTGGATCACCCGCCACGGACCGAT
CTTCATCGCCGATGGCACCCAGCGGCTCGCGCTACGCTGGACCGCCGCCGAAACCGGGATGCTCCAGTTCCCTTTTATCG
ACGTCGATCGCGCGCAGAATTGGGAACAGTTCACGGCCGCCGTCAAACGCCTTCCCGGCCCCGGCTCGAATTTCGTGTAT
GCCGATGTGGATGGCAACATCGGCTATCATGCTGTCGGTATGCTGCCGAGGCGCCGCAATTATCGCGGCGATATCCCGGT
GGATGGCTCCTCCGGAAACTTCGAATGGGACGGCTTCATTCCCTTCGAAGAGTTGCCCAGCGTCTACAATCCGCCCGGCG
GCATGATCGTCACCGCCAACCAGAATCCCTTCCCGGAGACTTTCCCGTACCCCTTGAACGGCAACTTCGCGCCGCCGCAG
CGCTTCATGCAGATCCGCGCCATGCTCTCCGCCCACGAAGGCTGGCGTCCCTCCGACATGCTCACCGTGCAGAAGGATGT
GTACTCGGCCTTCAGTCATTTTCTGGCCCGGCAGATCGTGGACGCATACCAGCGGCGCAACGCCCACAATCCGTCGCTCG
ACGATTCGGTTGCCATGCTGCGCGAATGGAATGGCCAGATGGATAAGGACCTGCCCGCGCCCTTCCTGATCACGCTCGCT
TACCAGCACGTGCGCCGCGCCGTCGCCGAAAACGCCTCCTCCGCCAGCGGCCTCGCCTACGAATTCAACATGGCGCCGGT
CGTGGTGCAGCGCCTTCTCACCGAGCGACCCGCCGGCTGGTTCGCCGACTACGACGACATGCTGCTCCGCGCGCTCGCCG
ACGCCGTGGAAGAAGCCCGCCGCATCCAGGGCCGGGAACCCAAACGCTGGCGCTACGGCCAGTACCTCTTTATCGCCATC
AACAATCCCGTGACTCACCAGATTCCACTGGTCGGCAAGTATTTCGATATCGGCCCCGTGCCCATGAGCGGCTCCACCAC
CACCGTCAAACAGACCAGCCGCAGCCTCGCCCCCTCCATGCGCATGACCGCCGACCTCGGCGATTGGGATCGCTCCATAC
TTAATATCCCCATCGGGCAATCCGGCCAGATTCTCTCCCGCCACTACAGCGATCAGTGGCTCGACTATTACAACGCTCGC
AGCTTCCCCATGCAGTTCAACAAAGTCGAGCCCGCGAGCACGCTGCAATTCCGTCCCACGCGCTGA

Upstream 100 bases:

>100_bases
ATGCGCCCCGGGTAAAGCATGGTAAAGCCGCCTGGCCGCCCAATTTACCTCCTCGGCTTAACCTCGCTAGCGGTTATGAT
TGAGAATTAACCCCTCGTAA

Downstream 100 bases:

>100_bases
CCCGCATGCTGAACTGGCTGCTGATCTTCGTGCCGGTAGCGATCGGGCTCGAGTTTTTCACGCCCGGGCAGCACACGTTG
ATCTTCATTACCGCCTGCCT

Product: penicillin amidase

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MSRNLVAHAVKYVNYAIAFALIIAAIAVYWYVWRPLPQRSGSIDAALSAPATVEFGAHGEPHIRAASLDDAFFLQGYVTA
QDRLFQMDALRRFAGGTLAEVFGPSLVESDREARKLRMRRIAEDAYGRLPDADRAAFAAYTRGVNQFIATHLNNLPVEFT
LLRYQPRPWSTVDCLLLCLHMYRNLTTTWKDEIIKNNMLAQGDRAKVEFLFPMRGLVDGNPGSNAWVLSGKHTASGKPLL
SNDMHLEYSLPGIWYMIYLDAPGLRVGGVSLPGAPGVIVGHNERIAWGITNLHFDVQDLYIEKFDDRTGRYLFRGQAEQA
RAEREIIRVKDRPAVEVDTWITRHGPIFIADGTQRLALRWTAAETGMLQFPFIDVDRAQNWEQFTAAVKRLPGPGSNFVY
ADVDGNIGYHAVGMLPRRRNYRGDIPVDGSSGNFEWDGFIPFEELPSVYNPPGGMIVTANQNPFPETFPYPLNGNFAPPQ
RFMQIRAMLSAHEGWRPSDMLTVQKDVYSAFSHFLARQIVDAYQRRNAHNPSLDDSVAMLREWNGQMDKDLPAPFLITLA
YQHVRRAVAENASSASGLAYEFNMAPVVVQRLLTERPAGWFADYDDMLLRALADAVEEARRIQGREPKRWRYGQYLFIAI
NNPVTHQIPLVGKYFDIGPVPMSGSTTTVKQTSRSLAPSMRMTADLGDWDRSILNIPIGQSGQILSRHYSDQWLDYYNAR
SFPMQFNKVEPASTLQFRPTR

Sequences:

>Translated_741_residues
MSRNLVAHAVKYVNYAIAFALIIAAIAVYWYVWRPLPQRSGSIDAALSAPATVEFGAHGEPHIRAASLDDAFFLQGYVTA
QDRLFQMDALRRFAGGTLAEVFGPSLVESDREARKLRMRRIAEDAYGRLPDADRAAFAAYTRGVNQFIATHLNNLPVEFT
LLRYQPRPWSTVDCLLLCLHMYRNLTTTWKDEIIKNNMLAQGDRAKVEFLFPMRGLVDGNPGSNAWVLSGKHTASGKPLL
SNDMHLEYSLPGIWYMIYLDAPGLRVGGVSLPGAPGVIVGHNERIAWGITNLHFDVQDLYIEKFDDRTGRYLFRGQAEQA
RAEREIIRVKDRPAVEVDTWITRHGPIFIADGTQRLALRWTAAETGMLQFPFIDVDRAQNWEQFTAAVKRLPGPGSNFVY
ADVDGNIGYHAVGMLPRRRNYRGDIPVDGSSGNFEWDGFIPFEELPSVYNPPGGMIVTANQNPFPETFPYPLNGNFAPPQ
RFMQIRAMLSAHEGWRPSDMLTVQKDVYSAFSHFLARQIVDAYQRRNAHNPSLDDSVAMLREWNGQMDKDLPAPFLITLA
YQHVRRAVAENASSASGLAYEFNMAPVVVQRLLTERPAGWFADYDDMLLRALADAVEEARRIQGREPKRWRYGQYLFIAI
NNPVTHQIPLVGKYFDIGPVPMSGSTTTVKQTSRSLAPSMRMTADLGDWDRSILNIPIGQSGQILSRHYSDQWLDYYNAR
SFPMQFNKVEPASTLQFRPTR
>Mature_740_residues
SRNLVAHAVKYVNYAIAFALIIAAIAVYWYVWRPLPQRSGSIDAALSAPATVEFGAHGEPHIRAASLDDAFFLQGYVTAQ
DRLFQMDALRRFAGGTLAEVFGPSLVESDREARKLRMRRIAEDAYGRLPDADRAAFAAYTRGVNQFIATHLNNLPVEFTL
LRYQPRPWSTVDCLLLCLHMYRNLTTTWKDEIIKNNMLAQGDRAKVEFLFPMRGLVDGNPGSNAWVLSGKHTASGKPLLS
NDMHLEYSLPGIWYMIYLDAPGLRVGGVSLPGAPGVIVGHNERIAWGITNLHFDVQDLYIEKFDDRTGRYLFRGQAEQAR
AEREIIRVKDRPAVEVDTWITRHGPIFIADGTQRLALRWTAAETGMLQFPFIDVDRAQNWEQFTAAVKRLPGPGSNFVYA
DVDGNIGYHAVGMLPRRRNYRGDIPVDGSSGNFEWDGFIPFEELPSVYNPPGGMIVTANQNPFPETFPYPLNGNFAPPQR
FMQIRAMLSAHEGWRPSDMLTVQKDVYSAFSHFLARQIVDAYQRRNAHNPSLDDSVAMLREWNGQMDKDLPAPFLITLAY
QHVRRAVAENASSASGLAYEFNMAPVVVQRLLTERPAGWFADYDDMLLRALADAVEEARRIQGREPKRWRYGQYLFIAIN
NPVTHQIPLVGKYFDIGPVPMSGSTTTVKQTSRSLAPSMRMTADLGDWDRSILNIPIGQSGQILSRHYSDQWLDYYNARS
FPMQFNKVEPASTLQFRPTR

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 83691; Mature: 83560

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNLVAHAVKYVNYAIAFALIIAAIAVYWYVWRPLPQRSGSIDAALSAPATVEFGAHGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCCCC
PHIRAASLDDAFFLQGYVTAQDRLFQMDALRRFAGGTLAEVFGPSLVESDREARKLRMRR
CCEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCHHHHHHHHHHH
IAEDAYGRLPDADRAAFAAYTRGVNQFIATHLNNLPVEFTLLRYQPRPWSTVDCLLLCLH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHH
MYRNLTTTWKDEIIKNNMLAQGDRAKVEFLFPMRGLVDGNPGSNAWVLSGKHTASGKPLL
HHHCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
SNDMHLEYSLPGIWYMIYLDAPGLRVGGVSLPGAPGVIVGHNERIAWGITNLHFDVQDLY
CCCCEEEEECCCEEEEEEECCCCCEECCCCCCCCCEEEEECCCEEEEEEEEEEEEHHHHH
IEKFDDRTGRYLFRGQAEQARAEREIIRVKDRPAVEVDTWITRHGPIFIADGTQRLALRW
HHHHCCCCCCEEEECCHHHHHHHHHHEEECCCCCEEEHHEEECCCCEEEECCCCEEEEEE
TAAETGMLQFPFIDVDRAQNWEQFTAAVKRLPGPGSNFVYADVDGNIGYHAVGMLPRRRN
EECCCCEEECCEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCC
YRGDIPVDGSSGNFEWDGFIPFEELPSVYNPPGGMIVTANQNPFPETFPYPLNGNFAPPQ
CCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHH
RFMQIRAMLSAHEGWRPSDMLTVQKDVYSAFSHFLARQIVDAYQRRNAHNPSLDDSVAML
HHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
REWNGQMDKDLPAPFLITLAYQHVRRAVAENASSASGLAYEFNMAPVVVQRLLTERPAGW
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCC
FADYDDMLLRALADAVEEARRIQGREPKRWRYGQYLFIAINNPVTHQIPLVGKYFDIGPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCEECCCEECEECCCCC
PMSGSTTTVKQTSRSLAPSMRMTADLGDWDRSILNIPIGQSGQILSRHYSDQWLDYYNAR
CCCCCCHHHHHHHHHHCCCHHEECCCCCCCCCEEECCCCCCCCHHHHHHCHHHHHHHCCC
SFPMQFNKVEPASTLQFRPTR
CCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure 
SRNLVAHAVKYVNYAIAFALIIAAIAVYWYVWRPLPQRSGSIDAALSAPATVEFGAHGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEECCCCC
PHIRAASLDDAFFLQGYVTAQDRLFQMDALRRFAGGTLAEVFGPSLVESDREARKLRMRR
CCEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCHHHHHHHHHHH
IAEDAYGRLPDADRAAFAAYTRGVNQFIATHLNNLPVEFTLLRYQPRPWSTVDCLLLCLH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHH
MYRNLTTTWKDEIIKNNMLAQGDRAKVEFLFPMRGLVDGNPGSNAWVLSGKHTASGKPLL
HHHCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
SNDMHLEYSLPGIWYMIYLDAPGLRVGGVSLPGAPGVIVGHNERIAWGITNLHFDVQDLY
CCCCEEEEECCCEEEEEEECCCCCEECCCCCCCCCEEEEECCCEEEEEEEEEEEEHHHHH
IEKFDDRTGRYLFRGQAEQARAEREIIRVKDRPAVEVDTWITRHGPIFIADGTQRLALRW
HHHHCCCCCCEEEECCHHHHHHHHHHEEECCCCCEEEHHEEECCCCEEEECCCCEEEEEE
TAAETGMLQFPFIDVDRAQNWEQFTAAVKRLPGPGSNFVYADVDGNIGYHAVGMLPRRRN
EECCCCEEECCEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCC
YRGDIPVDGSSGNFEWDGFIPFEELPSVYNPPGGMIVTANQNPFPETFPYPLNGNFAPPQ
CCCCCCCCCCCCCEEECCCCCHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHH
RFMQIRAMLSAHEGWRPSDMLTVQKDVYSAFSHFLARQIVDAYQRRNAHNPSLDDSVAML
HHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
REWNGQMDKDLPAPFLITLAYQHVRRAVAENASSASGLAYEFNMAPVVVQRLLTERPAGW
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCCCC
FADYDDMLLRALADAVEEARRIQGREPKRWRYGQYLFIAINNPVTHQIPLVGKYFDIGPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCEECCCEECEECCCCC
PMSGSTTTVKQTSRSLAPSMRMTADLGDWDRSILNIPIGQSGQILSRHYSDQWLDYYNAR
CCCCCCHHHHHHHHHHCCCHHEECCCCCCCCCEEECCCCCCCCHHHHHHCHHHHHHHCCC
SFPMQFNKVEPASTLQFRPTR
CCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]