Click here to switch to the map view.

The map label for this gene is czcB [H]

Identifier: 116623974

GI number: 116623974

Start: 6165563

End: 6166702

Strand: Reverse

Name: czcB [H]

Synonym: Acid_4886

Alternate gene names: 116623974

Gene position: 6166702-6165563 (Counterclockwise)

Preceding gene: 116623975

Following gene: 116623973

Centisome position: 61.88

GC content: 61.14

Gene sequence:

>1140_bases
ATGAAGCACGTGGCATTTCTACCGGCAGGTCTGGCAGTCGCGTTGAGTCTTTTGCTGGGAAGCTGCGCGCGGAACGTGAC
GGCCAAGAATCCCCAGCTCGAGGATCCCCCGGAGGTGGAGGTGGAGCACGAACAGGATGGGGTCCTGGTAAAGGTAAACC
ATCCGGAGCAGTTTCCGATGACGACCGCGAAGGCGCATTCCAGCGCGCCGGAGCTGAGCGTTACCGGAGTGGTGGGGGCG
GATATTGCGCGGAGTATGCCGGTGGTGTCGCTGGCTTCAGGACGGATTATCGAGATTCGAGCGCGGTTGGGCGACACGGT
CAAGAAAGGCCAATTGCTGATGCGGGTACAGAGCGCCGACCTTGCCGAAGCATTTTCGGATTACCGGCAGGCGGTCGCCG
ATGAGAAGCTGGCGGTTGCGCAACTGGCGCGATCAAAGATTCTCTTCGACAAGGGCGCGATCGCGCAGAAGGATCTGGAA
GTGGCGCAGCAGACGGAGGAGAAGGCGGACGTGGCTGTGGAAACCGCGATCGAACGGCTGCAGGTACTGGGTGCGGACAA
AGATCACCCTTCGATGGTGGTGGATGTTCTGGCGCCGGTATCGGGTGTGGTCACAGACCAGAAAGTAACGGCGTCCTCGG
GCACGCAAGGCCTGGGATCGCCGGATGCCTTCACGATATCCGACTTGTCGCGCGTGTGGGTGGTTTGCGATGTGTTTGAG
AACGACCTGTCTTTCGTGAAGCTCAACGAGGAAGCCGAGATTCGCCTGAACGCGTATCCGAACCGTGTGTTGAGAGGGAG
GATCAGCAATATAGGAGCGATTCTCGACCCGAATACGCGGACCGCCAAGGTTCGTGTGGAGGTGGAGAATCCGGGGATGA
TGCGACTCGGAATGTTCGTGCAGGCGAAGTTCCACGGCAGCCAGGCGCAAGTCCGCGGGCTATTGCCGGCGTCGGCGATC
GTTCACATTCACGACCGGGACTGGGTGTATGTGGCAAGCGGCCCGAACACGTTCCGCCGCGTGGAAGTGCGCAGCGGACA
GATGATTCCGCCAGGCCGGCAGGAGATTTTATCGGGGATCCGGCCGGGCGACCGCGTGGTGGCGGACGCATTGCAGCTCG
AGAACACGGCGGACCGGTAA

Upstream 100 bases:

>100_bases
AGGATTACCGCAATATTCAATTGAGCTATCTGAATCTGGTGGGGTCGTATTTGAGCGCCGCCAACCAAATGAACTTCGCC
GTGGGGCGTGAGGTGATTCC

Downstream 100 bases:

>100_bases
GGGAATATGATCCGCACGATTGTCGATTTCGCGCTGAACAACCGTTTCCTGATGCTGGCGGCGGCCGCGCTGCTGATGGT
GTGGGGCGTGATCTCTTTTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKHVAFLPAGLAVALSLLLGSCARNVTAKNPQLEDPPEVEVEHEQDGVLVKVNHPEQFPMTTAKAHSSAPELSVTGVVGA
DIARSMPVVSLASGRIIEIRARLGDTVKKGQLLMRVQSADLAEAFSDYRQAVADEKLAVAQLARSKILFDKGAIAQKDLE
VAQQTEEKADVAVETAIERLQVLGADKDHPSMVVDVLAPVSGVVTDQKVTASSGTQGLGSPDAFTISDLSRVWVVCDVFE
NDLSFVKLNEEAEIRLNAYPNRVLRGRISNIGAILDPNTRTAKVRVEVENPGMMRLGMFVQAKFHGSQAQVRGLLPASAI
VHIHDRDWVYVASGPNTFRRVEVRSGQMIPPGRQEILSGIRPGDRVVADALQLENTADR

Sequences:

>Translated_379_residues
MKHVAFLPAGLAVALSLLLGSCARNVTAKNPQLEDPPEVEVEHEQDGVLVKVNHPEQFPMTTAKAHSSAPELSVTGVVGA
DIARSMPVVSLASGRIIEIRARLGDTVKKGQLLMRVQSADLAEAFSDYRQAVADEKLAVAQLARSKILFDKGAIAQKDLE
VAQQTEEKADVAVETAIERLQVLGADKDHPSMVVDVLAPVSGVVTDQKVTASSGTQGLGSPDAFTISDLSRVWVVCDVFE
NDLSFVKLNEEAEIRLNAYPNRVLRGRISNIGAILDPNTRTAKVRVEVENPGMMRLGMFVQAKFHGSQAQVRGLLPASAI
VHIHDRDWVYVASGPNTFRRVEVRSGQMIPPGRQEILSGIRPGDRVVADALQLENTADR
>Mature_379_residues
MKHVAFLPAGLAVALSLLLGSCARNVTAKNPQLEDPPEVEVEHEQDGVLVKVNHPEQFPMTTAKAHSSAPELSVTGVVGA
DIARSMPVVSLASGRIIEIRARLGDTVKKGQLLMRVQSADLAEAFSDYRQAVADEKLAVAQLARSKILFDKGAIAQKDLE
VAQQTEEKADVAVETAIERLQVLGADKDHPSMVVDVLAPVSGVVTDQKVTASSGTQGLGSPDAFTISDLSRVWVVCDVFE
NDLSFVKLNEEAEIRLNAYPNRVLRGRISNIGAILDPNTRTAKVRVEVENPGMMRLGMFVQAKFHGSQAQVRGLLPASAI
VHIHDRDWVYVASGPNTFRRVEVRSGQMIPPGRQEILSGIRPGDRVVADALQLENTADR

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40965; Mature: 40965

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVAFLPAGLAVALSLLLGSCARNVTAKNPQLEDPPEVEVEHEQDGVLVKVNHPEQFPM
CCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCC
TTAKAHSSAPELSVTGVVGADIARSMPVVSLASGRIIEIRARLGDTVKKGQLLMRVQSAD
CHHHCCCCCCCEEEEEEEHHHHHHCCCEEEECCCCEEEEEEHHCCCHHCCEEEEEEHHHH
LAEAFSDYRQAVADEKLAVAQLARSKILFDKGAIAQKDLEVAQQTEEKADVAVETAIERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QVLGADKDHPSMVVDVLAPVSGVVTDQKVTASSGTQGLGSPDAFTISDLSRVWVVCDVFE
HHHCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEHHHHHEEEEEEEECC
NDLSFVKLNEEAEIRLNAYPNRVLRGRISNIGAILDPNTRTAKVRVEVENPGMMRLGMFV
CCCEEEEECCCCEEEEECCCCHHHHHHHHCCCEEECCCCCEEEEEEEECCCCEEEEEEEE
QAKFHGSQAQVRGLLPASAIVHIHDRDWVYVASGPNTFRRVEVRSGQMIPPGRQEILSGI
EEEECCCHHHHEECCCCEEEEEEECCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCC
RPGDRVVADALQLENTADR
CCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKHVAFLPAGLAVALSLLLGSCARNVTAKNPQLEDPPEVEVEHEQDGVLVKVNHPEQFPM
CCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCC
TTAKAHSSAPELSVTGVVGADIARSMPVVSLASGRIIEIRARLGDTVKKGQLLMRVQSAD
CHHHCCCCCCCEEEEEEEHHHHHHCCCEEEECCCCEEEEEEHHCCCHHCCEEEEEEHHHH
LAEAFSDYRQAVADEKLAVAQLARSKILFDKGAIAQKDLEVAQQTEEKADVAVETAIERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QVLGADKDHPSMVVDVLAPVSGVVTDQKVTASSGTQGLGSPDAFTISDLSRVWVVCDVFE
HHHCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEHHHHHEEEEEEEECC
NDLSFVKLNEEAEIRLNAYPNRVLRGRISNIGAILDPNTRTAKVRVEVENPGMMRLGMFV
CCCEEEEECCCCEEEEECCCCHHHHHHHHCCCEEECCCCCEEEEEEEECCCCEEEEEEEE
QAKFHGSQAQVRGLLPASAIVHIHDRDWVYVASGPNTFRRVEVRSGQMIPPGRQEILSGI
EEEECCCHHHHEECCCCEEEEEEECCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCC
RPGDRVVADALQLENTADR
CCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]