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The map label for this gene is spoVD [H]

Identifier: 116623922

GI number: 116623922

Start: 6107420

End: 6108670

Strand: Reverse

Name: spoVD [H]

Synonym: Acid_4834

Alternate gene names: 116623922

Gene position: 6108670-6107420 (Counterclockwise)

Preceding gene: 116623924

Following gene: 116623921

Centisome position: 61.3

GC content: 62.59

Gene sequence:

>1251_bases
ATGAACAGGTCACCCCTACCCCCGGCTCATCGATCCATCACCTTCCTTATCGTGCTCCATCTGATTGCTTCGCTTGGAAT
TAGCGGCACGGTGCCGCCCAAGAAGAGACATCGTAAGACGAGTACGGTACACAAAGCTGCCACGGTTAAACCGCGCCCTA
AGGCTATGGCTGCCACTGCAACGCCGCACGTGGCGGTACGCAGGGTTGCGGCTTCGGCTCAGCGGCAGGCGGTAGGCCCG
CATCCGGTGGCAGTGGCGGCGCCGATTATCGCGGGCGGTCCCTGGACGAGCCCGACTTTTGCAGATTCAACGGACGGCGA
TAACATCGACGGCGAGGACCTGGACATTCGACGAGCCGCAGTGGACGCGCTGGGACAGTACAACGGGTCGGTGGTTGTGG
TGGATCCCAGCAACGGTCGCGTACTGACGATGGTTAATCAGAAGGTCGCGCTGAGCACGGGGTTTCAGCCGTGCTCGACG
GTTAAGGTGTCGGTTGCGCTGGCGGCATTGAGCGAGAAGGTGATCGAGCCTTCCACGAAGTACCGTTTGGGCGGGATGAA
AATGGATCTCACCTACGCGCTGGCGCACTCCAACAACTATTACTTCGCGACGTTGGGGACGAAGCTCGGATTCGAGCGCG
TGAGTTACTATTCGCGGCTGTTCGGTTACGGAGAGAAGGCCGGGCTGAACATCGCGGGAGAGCAGCCGGGCCGGTATCCG
ACGGCGCCGCCGAAGAATGGCGGGGTCGGGATGCTAACGAGTTTCGGCGAGGAGATTCAGCAGACGCCTTTGCAACTGGC
GGCGCTGATGAGCTCGATCGCGAATGGCGGGACACTGTACTACCTGCAGTATCCGAAGTCGCAGACGGAAGTGCAGAACT
TCGTGCCCCGGGTGAAGCGGCGGCTGGATATCGCTGGGGTGATTCCCCAAGTGAAACCGGGAATGCGCGGAGCGGTCGAG
TTCGGCACGGCGCACCGGGCGCGGGAAGACGGACCGATCGCGGGGAAGACGGGCACGTGCAGCGAGAATCATACCCACCT
CGGCTGGTTCGGGGCCTTCAACGACGCCGGCGATCGGAAGCTGGTGGTGGTAGTGCTGCTCACCGGCGGGCGTCCGGCGA
TTGGGCCGCTGGCGGCGGGAATCGCGGGCGACGTTTACCGGCGGCTGGGAGAGAAGAATTACTTCCACACCGCGTCGGAC
GCGATGACACCGGCGTCGCTGGTGTCCAGGCAGATTTGCTGCTCCAAGTAG

Upstream 100 bases:

>100_bases
AGCACAGAATTAGATAGTCGGCTGCTCCGGCCGAAAGTTGTGTCGCTCTGGCCATATTGATCCTCCACGAATTCACCGAT
AGGTGAATAGCGTCATTAGT

Downstream 100 bases:

>100_bases
GCTTCCCGGCGGCACTCCGCACTGATACGATGTTCTGGTGCGAACGCTAACGGCTCTCTTGTTTGCATCGGTCTGCTGGT
CGCAGCAGGCGGAATTCGAA

Product: penicillin-binding protein, transpeptidase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNRSPLPPAHRSITFLIVLHLIASLGISGTVPPKKRHRKTSTVHKAATVKPRPKAMAATATPHVAVRRVAASAQRQAVGP
HPVAVAAPIIAGGPWTSPTFADSTDGDNIDGEDLDIRRAAVDALGQYNGSVVVVDPSNGRVLTMVNQKVALSTGFQPCST
VKVSVALAALSEKVIEPSTKYRLGGMKMDLTYALAHSNNYYFATLGTKLGFERVSYYSRLFGYGEKAGLNIAGEQPGRYP
TAPPKNGGVGMLTSFGEEIQQTPLQLAALMSSIANGGTLYYLQYPKSQTEVQNFVPRVKRRLDIAGVIPQVKPGMRGAVE
FGTAHRAREDGPIAGKTGTCSENHTHLGWFGAFNDAGDRKLVVVVLLTGGRPAIGPLAAGIAGDVYRRLGEKNYFHTASD
AMTPASLVSRQICCSK

Sequences:

>Translated_416_residues
MNRSPLPPAHRSITFLIVLHLIASLGISGTVPPKKRHRKTSTVHKAATVKPRPKAMAATATPHVAVRRVAASAQRQAVGP
HPVAVAAPIIAGGPWTSPTFADSTDGDNIDGEDLDIRRAAVDALGQYNGSVVVVDPSNGRVLTMVNQKVALSTGFQPCST
VKVSVALAALSEKVIEPSTKYRLGGMKMDLTYALAHSNNYYFATLGTKLGFERVSYYSRLFGYGEKAGLNIAGEQPGRYP
TAPPKNGGVGMLTSFGEEIQQTPLQLAALMSSIANGGTLYYLQYPKSQTEVQNFVPRVKRRLDIAGVIPQVKPGMRGAVE
FGTAHRAREDGPIAGKTGTCSENHTHLGWFGAFNDAGDRKLVVVVLLTGGRPAIGPLAAGIAGDVYRRLGEKNYFHTASD
AMTPASLVSRQICCSK
>Mature_416_residues
MNRSPLPPAHRSITFLIVLHLIASLGISGTVPPKKRHRKTSTVHKAATVKPRPKAMAATATPHVAVRRVAASAQRQAVGP
HPVAVAAPIIAGGPWTSPTFADSTDGDNIDGEDLDIRRAAVDALGQYNGSVVVVDPSNGRVLTMVNQKVALSTGFQPCST
VKVSVALAALSEKVIEPSTKYRLGGMKMDLTYALAHSNNYYFATLGTKLGFERVSYYSRLFGYGEKAGLNIAGEQPGRYP
TAPPKNGGVGMLTSFGEEIQQTPLQLAALMSSIANGGTLYYLQYPKSQTEVQNFVPRVKRRLDIAGVIPQVKPGMRGAVE
FGTAHRAREDGPIAGKTGTCSENHTHLGWFGAFNDAGDRKLVVVVLLTGGRPAIGPLAAGIAGDVYRRLGEKNYFHTASD
AMTPASLVSRQICCSK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=330, Percent_Identity=26.0606060606061, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 44226; Mature: 44226

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSPLPPAHRSITFLIVLHLIASLGISGTVPPKKRHRKTSTVHKAATVKPRPKAMAATA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECC
TPHVAVRRVAASAQRQAVGPHPVAVAAPIIAGGPWTSPTFADSTDGDNIDGEDLDIRRAA
CHHHHHHHHHHHHHHHCCCCCCHHEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VDALGQYNGSVVVVDPSNGRVLTMVNQKVALSTGFQPCSTVKVSVALAALSEKVIEPSTK
HHHHHHCCCEEEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
YRLGGMKMDLTYALAHSNNYYFATLGTKLGFERVSYYSRLFGYGEKAGLNIAGEQPGRYP
EEECCEEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
TAPPKNGGVGMLTSFGEEIQQTPLQLAALMSSIANGGTLYYLQYPKSQTEVQNFVPRVKR
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
RLDIAGVIPQVKPGMRGAVEFGTAHRAREDGPIAGKTGTCSENHTHLGWFGAFNDAGDRK
HHHHHHCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCE
LVVVVLLTGGRPAIGPLAAGIAGDVYRRLGEKNYFHTASDAMTPASLVSRQICCSK
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNRSPLPPAHRSITFLIVLHLIASLGISGTVPPKKRHRKTSTVHKAATVKPRPKAMAATA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECC
TPHVAVRRVAASAQRQAVGPHPVAVAAPIIAGGPWTSPTFADSTDGDNIDGEDLDIRRAA
CHHHHHHHHHHHHHHHCCCCCCHHEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VDALGQYNGSVVVVDPSNGRVLTMVNQKVALSTGFQPCSTVKVSVALAALSEKVIEPSTK
HHHHHHCCCEEEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCC
YRLGGMKMDLTYALAHSNNYYFATLGTKLGFERVSYYSRLFGYGEKAGLNIAGEQPGRYP
EEECCEEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
TAPPKNGGVGMLTSFGEEIQQTPLQLAALMSSIANGGTLYYLQYPKSQTEVQNFVPRVKR
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
RLDIAGVIPQVKPGMRGAVEFGTAHRAREDGPIAGKTGTCSENHTHLGWFGAFNDAGDRK
HHHHHHCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCE
LVVVVLLTGGRPAIGPLAAGIAGDVYRRLGEKNYFHTASDAMTPASLVSRQICCSK
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEECCHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]