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The map label for this gene is iorA [H]

Identifier: 116623887

GI number: 116623887

Start: 6068435

End: 6068932

Strand: Direct

Name: iorA [H]

Synonym: Acid_4799

Alternate gene names: 116623887

Gene position: 6068435-6068932 (Clockwise)

Preceding gene: 116623886

Following gene: 116623888

Centisome position: 60.89

GC content: 60.24

Gene sequence:

>498_bases
ATGAGCAATATCACGCTGAAGGTGAACGGCCGTACGCACACCGTGGACGTCGAGCCGGCCACGCCGCTGCTCTATATCCT
TCGCAACGATCTGGGCTTGCAAGGACCCCACTTCGGATGCGGACTGGGCCAGTGCGGCGCCTGCACGGTCATCATTAACG
GTGCGGCCGTACGTTCCTGCATCCTGCCCGCGTCTTCCGTCAAGGGCGAAATCACCACTCTGGAAGGGATCGCTTCGAAT
GGCAAATTGCACCCGCTGCAACAAGCCTGGATTGAGGAGCAGGTCCCGCAATGCGGCTTCTGCCAGAACGGACAAATCCT
GACCGCCAAAGCCATGCTGGACAAAAATCCACATCCCACCGACGCGCAAATCCGCGAAGCCATGAACGGGACCTTGTGCC
GCTGCATGAGTTACTACCGCGTTCAGACGGCGATCAAACGCGCGGCCAGGACGCTTGCCGGCGCTTCGCCCAACTCCGGA
AATGAGGTGGTGGCATGA

Upstream 100 bases:

>100_bases
AATCTCGCGCCGCGGCGAGCTCGTTGCAAGCGGCATCCCTTCCGGCACATAATCCTGTCTATACAGGACTGCCGGTCAAC
GGCGCCAGGAGGGTCGATCG

Downstream 100 bases:

>100_bases
GCGATCCCGGCGGAATTCCGCGGCACATCGAAGAGATCCTGGTGACCAATCGCCGGGGCTTCCTCAAAAGCGCGGGCATG
CTCGCGGTGAGTTTCGGAGC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSNITLKVNGRTHTVDVEPATPLLYILRNDLGLQGPHFGCGLGQCGACTVIINGAAVRSCILPASSVKGEITTLEGIASN
GKLHPLQQAWIEEQVPQCGFCQNGQILTAKAMLDKNPHPTDAQIREAMNGTLCRCMSYYRVQTAIKRAARTLAGASPNSG
NEVVA

Sequences:

>Translated_165_residues
MSNITLKVNGRTHTVDVEPATPLLYILRNDLGLQGPHFGCGLGQCGACTVIINGAAVRSCILPASSVKGEITTLEGIASN
GKLHPLQQAWIEEQVPQCGFCQNGQILTAKAMLDKNPHPTDAQIREAMNGTLCRCMSYYRVQTAIKRAARTLAGASPNSG
NEVVA
>Mature_164_residues
SNITLKVNGRTHTVDVEPATPLLYILRNDLGLQGPHFGCGLGQCGACTVIINGAAVRSCILPASSVKGEITTLEGIASNG
KLHPLQQAWIEEQVPQCGFCQNGQILTAKAMLDKNPHPTDAQIREAMNGTLCRCMSYYRVQTAIKRAARTLAGASPNSGN
EVVA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=162, Percent_Identity=35.1851851851852, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI71773480, Length=163, Percent_Identity=33.1288343558282, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=41.9753086419753, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789232, Length=152, Percent_Identity=39.4736842105263, Blast_Score=101, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=37.6623376623377, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=157, Percent_Identity=37.5796178343949, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=165, Percent_Identity=38.1818181818182, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17737937, Length=168, Percent_Identity=35.7142857142857, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=29.4478527607362, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=29.4478527607362, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17530; Mature: 17399

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNITLKVNGRTHTVDVEPATPLLYILRNDLGLQGPHFGCGLGQCGACTVIINGAAVRSC
CCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
ILPASSVKGEITTLEGIASNGKLHPLQQAWIEEQVPQCGFCQNGQILTAKAMLDKNPHPT
HCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCCCCCC
DAQIREAMNGTLCRCMSYYRVQTAIKRAARTLAGASPNSGNEVVA
CHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SNITLKVNGRTHTVDVEPATPLLYILRNDLGLQGPHFGCGLGQCGACTVIINGAAVRSC
CCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCHHHHHH
ILPASSVKGEITTLEGIASNGKLHPLQQAWIEEQVPQCGFCQNGQILTAKAMLDKNPHPT
HCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCCCCCC
DAQIREAMNGTLCRCMSYYRVQTAIKRAARTLAGASPNSGNEVVA
CHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]