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The map label for this gene is tagO [H]

Identifier: 116623746

GI number: 116623746

Start: 5893390

End: 5894829

Strand: Direct

Name: tagO [H]

Synonym: Acid_4658

Alternate gene names: 116623746

Gene position: 5893390-5894829 (Clockwise)

Preceding gene: 116623744

Following gene: 116623747

Centisome position: 59.14

GC content: 62.64

Gene sequence:

>1440_bases
ATGCTCGTTCTTTTCGACGTCAGCTGCCTTGCGTTTTTGTTTGCGCTGGTTCTGACCCCATGGGTTAGAAACGCGGCAAA
TCGTCTGGGCCTTGTCGATAAACCCGATGCCGCGCGCAAAATGCACCTCGTCTCGGTCCCCCGGGTCGGCGGAGTGGGTG
TCGCCCTGGCATACGCCTTGGCCTTGGTTTTTGTCGCCTTCGCGCCCTATCGCAACCTGTCCGTCGACGTCCCCGGGAGC
ATCGACGCCGCGCTGAAACTGGCGCCGGCTGCCATCGTAATCCTGCTGATCGGGCTGGCCGACGATATCCGCGGCCTGCG
CCCCTGGCACAAATTGCTCGGCGAGGTCGTCGCCGCCATTCTCGCCTACCAGGCAGGCTTCGGCGTGTCCGTGTTTCGCG
GCCAGCCTGTCGGCGAATGGGTGTCGCCGGTCCTGACCGTACTTTGGTTGGTAGGCTGCTGCAACGCGTTGAACCTGATC
GATGGAATCGATGGCCTCGCAGCCGGCGTCGGAATCTTCGCGACCCTGACTGCCTTCGTGGCCGCGCTCGTGCACAACAG
CCTGGAACTGGCCCTCGTGACCGCGCCCCTGATCGGCGCATTGCTCGGCTTCCTCCGTTACAACTTCAATCCGGCCTCGA
TTTTTCTCGGCGATTCCGGTAGCCTGCTGATCGGCTTCCTGCTCGGCTGCTTCGGAGCCATGTGGAGCCAGAAGTCAGCC
ACTCTCCTCGGCATGACGGCCCCTCTCATCGCGCTAGCGATGCCGCTGCTGGATACGGCCCTGGCCATCGCCCGGCGGTT
CCTGCGCCGGCAGCCGATCTTCGGCGCCGACCGGGGCCACATCCACCATCGCTTGTTGGATCGTGGGCTCACGCCGCGAC
GTGTGGCTCTCCTGCTATATGGTGCCTGCGGCCTGGCTGCCGCTTTTTCCCTGATCCAGGACGTGGGCCATGACCAGTTC
GGTGGCTTGATCATCATTCTGTTTTGCGGAGCCGCCTGGGTAGGAGTACAACACCTGGGCTATGCCGAGTTCGGGGTTGC
CAGCAGATTAGTCCTGCGCGGTTCTTTCCGCAGCATGGTCAATGCGCAACTACGCCTCCAGCAGTTTGAAAGGAATCTGG
CGACCGCGGTAGGTCTCGACGATGCCTGGACGTTGATCTCCGCGGGTGCGGAGGAGTTCGGCTGGACCGGTGTCCGCCTG
CAGTTGTGCGGACGCATCTGGGATTCAACACCAAACGTGGAATCGGCCGCTTATTGGCAGGTACGGGTGCCGCTGCCAGA
GGGTCAATATCTGAACCTCAGCAGCGATCCGGCGGTGGACATCCATCCCGTGTTGTTGGCCAGTTTTCCCAAACTGCTGG
AGAAGTTCCTGGTCTCCCGTTATGCGGCGACGCCCGAAATACCGGCGACCGCGCCAGCAGCCACCGGGGTCGAAGCTTGA

Upstream 100 bases:

>100_bases
GCTCAATTCCGGCGACCACTGGTTTTACTAAGGTGGTACTCGAAGTATCGGAATAGTCCTTACCTGCCGCTAACATCCGG
CCTACACTGAATCAATCGCT

Downstream 100 bases:

>100_bases
CACTTTTGAGGGCGCTTCCCTGCCCCCGACCCGCCAGCATCTGCCGCAAGAGAACCACACCACGATGCGGGTCATAGTCC
GGTTGCCCGGGAATCCGTCG

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MLVLFDVSCLAFLFALVLTPWVRNAANRLGLVDKPDAARKMHLVSVPRVGGVGVALAYALALVFVAFAPYRNLSVDVPGS
IDAALKLAPAAIVILLIGLADDIRGLRPWHKLLGEVVAAILAYQAGFGVSVFRGQPVGEWVSPVLTVLWLVGCCNALNLI
DGIDGLAAGVGIFATLTAFVAALVHNSLELALVTAPLIGALLGFLRYNFNPASIFLGDSGSLLIGFLLGCFGAMWSQKSA
TLLGMTAPLIALAMPLLDTALAIARRFLRRQPIFGADRGHIHHRLLDRGLTPRRVALLLYGACGLAAAFSLIQDVGHDQF
GGLIIILFCGAAWVGVQHLGYAEFGVASRLVLRGSFRSMVNAQLRLQQFERNLATAVGLDDAWTLISAGAEEFGWTGVRL
QLCGRIWDSTPNVESAAYWQVRVPLPEGQYLNLSSDPAVDIHPVLLASFPKLLEKFLVSRYAATPEIPATAPAATGVEA

Sequences:

>Translated_479_residues
MLVLFDVSCLAFLFALVLTPWVRNAANRLGLVDKPDAARKMHLVSVPRVGGVGVALAYALALVFVAFAPYRNLSVDVPGS
IDAALKLAPAAIVILLIGLADDIRGLRPWHKLLGEVVAAILAYQAGFGVSVFRGQPVGEWVSPVLTVLWLVGCCNALNLI
DGIDGLAAGVGIFATLTAFVAALVHNSLELALVTAPLIGALLGFLRYNFNPASIFLGDSGSLLIGFLLGCFGAMWSQKSA
TLLGMTAPLIALAMPLLDTALAIARRFLRRQPIFGADRGHIHHRLLDRGLTPRRVALLLYGACGLAAAFSLIQDVGHDQF
GGLIIILFCGAAWVGVQHLGYAEFGVASRLVLRGSFRSMVNAQLRLQQFERNLATAVGLDDAWTLISAGAEEFGWTGVRL
QLCGRIWDSTPNVESAAYWQVRVPLPEGQYLNLSSDPAVDIHPVLLASFPKLLEKFLVSRYAATPEIPATAPAATGVEA
>Mature_479_residues
MLVLFDVSCLAFLFALVLTPWVRNAANRLGLVDKPDAARKMHLVSVPRVGGVGVALAYALALVFVAFAPYRNLSVDVPGS
IDAALKLAPAAIVILLIGLADDIRGLRPWHKLLGEVVAAILAYQAGFGVSVFRGQPVGEWVSPVLTVLWLVGCCNALNLI
DGIDGLAAGVGIFATLTAFVAALVHNSLELALVTAPLIGALLGFLRYNFNPASIFLGDSGSLLIGFLLGCFGAMWSQKSA
TLLGMTAPLIALAMPLLDTALAIARRFLRRQPIFGADRGHIHHRLLDRGLTPRRVALLLYGACGLAAAFSLIQDVGHDQF
GGLIIILFCGAAWVGVQHLGYAEFGVASRLVLRGSFRSMVNAQLRLQQFERNLATAVGLDDAWTLISAGAEEFGWTGVRL
QLCGRIWDSTPNVESAAYWQVRVPLPEGQYLNLSSDPAVDIHPVLLASFPKLLEKFLVSRYAATPEIPATAPAATGVEA

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=307, Percent_Identity=28.0130293159609, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 51029; Mature: 51029

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLFDVSCLAFLFALVLTPWVRNAANRLGLVDKPDAARKMHLVSVPRVGGVGVALAYAL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCHHHHHHHHH
ALVFVAFAPYRNLSVDVPGSIDAALKLAPAAIVILLIGLADDIRGLRPWHKLLGEVVAAI
HHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAYQAGFGVSVFRGQPVGEWVSPVLTVLWLVGCCNALNLIDGIDGLAAGVGIFATLTAFV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AALVHNSLELALVTAPLIGALLGFLRYNFNPASIFLGDSGSLLIGFLLGCFGAMWSQKSA
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCC
TLLGMTAPLIALAMPLLDTALAIARRFLRRQPIFGADRGHIHHRLLDRGLTPRRVALLLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
GACGLAAAFSLIQDVGHDQFGGLIIILFCGAAWVGVQHLGYAEFGVASRLVLRGSFRSMV
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NAQLRLQQFERNLATAVGLDDAWTLISAGAEEFGWTGVRLQLCGRIWDSTPNVESAAYWQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEE
VRVPLPEGQYLNLSSDPAVDIHPVLLASFPKLLEKFLVSRYAATPEIPATAPAATGVEA
EEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVLFDVSCLAFLFALVLTPWVRNAANRLGLVDKPDAARKMHLVSVPRVGGVGVALAYAL
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEECCCCCCHHHHHHHHH
ALVFVAFAPYRNLSVDVPGSIDAALKLAPAAIVILLIGLADDIRGLRPWHKLLGEVVAAI
HHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAYQAGFGVSVFRGQPVGEWVSPVLTVLWLVGCCNALNLIDGIDGLAAGVGIFATLTAFV
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AALVHNSLELALVTAPLIGALLGFLRYNFNPASIFLGDSGSLLIGFLLGCFGAMWSQKSA
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCC
TLLGMTAPLIALAMPLLDTALAIARRFLRRQPIFGADRGHIHHRLLDRGLTPRRVALLLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
GACGLAAAFSLIQDVGHDQFGGLIIILFCGAAWVGVQHLGYAEFGVASRLVLRGSFRSMV
HHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NAQLRLQQFERNLATAVGLDDAWTLISAGAEEFGWTGVRLQLCGRIWDSTPNVESAAYWQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEE
VRVPLPEGQYLNLSSDPAVDIHPVLLASFPKLLEKFLVSRYAATPEIPATAPAATGVEA
EEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]