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The map label for this gene is 116623571

Identifier: 116623571

GI number: 116623571

Start: 5673583

End: 5674761

Strand: Direct

Name: 116623571

Synonym: Acid_4481

Alternate gene names: NA

Gene position: 5673583-5674761 (Clockwise)

Preceding gene: 116623570

Following gene: 116623572

Centisome position: 56.93

GC content: 59.63

Gene sequence:

>1179_bases
ATGAAAGCTTACCTGATCGGAATTGTGGCAGCTCTGATGCTGACGCCGGAGATTGGACTTGCCCAGGATGCGGCCGACAT
GATCCGCGGAATCGAGTCGTCGCAGCTGGCGAGTCGTCAGGGCGACCCGGGCTCTCTCACGATGGAGCAGTTACTGGCTT
TCTATCACGTATCGAGCCTGAGCATGGCGGTAATTCATGACTTCCGGATCCACTGGGCAAAGTCGTGGGGCATGGCCGAT
GCGCGGGCTGGAACGCCCGCAACCAACGACACTTTGTACCGGGCGGCGTCCATCAGCAAACCGGTGGCCGCGATGGCGAC
GCTGAAAGCGATTCAGAATGGCGTGTTCGGGCTCGATCAGGACGTCAACACAATCCTGAAATCCTGGAAGTTCCCGGAGA
GCTCCTATACAGAGCGGCAGCCGATAACACTCCGGGCGTTATTGAGCCACACCGCCGGAACGGGCGATGGCTTTGGTTTC
GATGGCTATGAGCCGGGCGCGAAATTGCCCACGGTTCCTCAAATGCTCTCCGGTCAGCCGCCTGCGAATAACGGGGAGGT
GCGCCTGGTGAGACCTCCGTCCACGGCGTACCAGTATTCAGGTGGAGGAGTGATGGCGGCGCAGTTAGCCTTAACGGATG
CGGTTGGCAAGCCGTTTGAGACGATTGCAGATGAGTGGATCCTGCGGCCGATCGGCATGTCGAAAAGTACCTTTGCACAG
CCGCTTCCCCCGGATCTCGAACGCCATGCCGCGCGGGAATATGCTGACAGCGGTAAAGCGGTCGGAACCCAATGGTCCGC
GTTTCCACAGCTGGCCGCGGCCGGACTTTGGAGCACGCCTACGGACCTCGCGAAGTTCGCTATCGAAGTGCAGAACACGC
TGGCCGGAAAGTCGACGCGGATCCTGAACCGGACGACGATGCAGGAGATGGTGACACCGGTTGGCGTGGGGCCTTACGCG
GTGGGTTTCGAGATCCTGAAGCGCGGCGAGGGTTGGTACTTCAGGAAATGGGGCAGCAGTTTGGGATACAAAAGCCAGCT
CCTTGCCCATCGTTCCAAAGGATACGGCGTCGTGATCATGTTGAGCGGGAATAGCGAACCAATCATCAACGAGTTGGTGG
AGCGAGTTGCCCGCGCCTACCGCTGGGATAGCCTGGATCAGCCAATCCCACAACGCTAG

Upstream 100 bases:

>100_bases
TTGCGGTCGTCGCTGCCGCCGCAAACCCGACCGCATTGCCCCGTAGTGGAGGCCGCTTTCACGCGCGTAACCTTTTCGCA
CAAGGTCAGTAATCATAGAC

Downstream 100 bases:

>100_bases
TGGATCGTTGATGAATACACGCGGATCCTCGCATGCTCTCCGAACGTCTTTTTTGCCGTCGCAGGAGCCAGTGGCAGGAC
CGTTGTTCACTACCTTGCCC

Product: beta-lactamase

Products: substituted beta-amino acid

Alternate protein names: Non-Ribosomal Peptide Synthetase; Beta-Lactamase Family Protein; Beta-Lactamase Class C; Amino Acid Adenylation Domain-Containing Protein; FmtA-Like Protein; Non-Ribosimal Peptide Synthetase; D-Aminoacylase

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKAYLIGIVAALMLTPEIGLAQDAADMIRGIESSQLASRQGDPGSLTMEQLLAFYHVSSLSMAVIHDFRIHWAKSWGMAD
ARAGTPATNDTLYRAASISKPVAAMATLKAIQNGVFGLDQDVNTILKSWKFPESSYTERQPITLRALLSHTAGTGDGFGF
DGYEPGAKLPTVPQMLSGQPPANNGEVRLVRPPSTAYQYSGGGVMAAQLALTDAVGKPFETIADEWILRPIGMSKSTFAQ
PLPPDLERHAAREYADSGKAVGTQWSAFPQLAAAGLWSTPTDLAKFAIEVQNTLAGKSTRILNRTTMQEMVTPVGVGPYA
VGFEILKRGEGWYFRKWGSSLGYKSQLLAHRSKGYGVVIMLSGNSEPIINELVERVARAYRWDSLDQPIPQR

Sequences:

>Translated_392_residues
MKAYLIGIVAALMLTPEIGLAQDAADMIRGIESSQLASRQGDPGSLTMEQLLAFYHVSSLSMAVIHDFRIHWAKSWGMAD
ARAGTPATNDTLYRAASISKPVAAMATLKAIQNGVFGLDQDVNTILKSWKFPESSYTERQPITLRALLSHTAGTGDGFGF
DGYEPGAKLPTVPQMLSGQPPANNGEVRLVRPPSTAYQYSGGGVMAAQLALTDAVGKPFETIADEWILRPIGMSKSTFAQ
PLPPDLERHAAREYADSGKAVGTQWSAFPQLAAAGLWSTPTDLAKFAIEVQNTLAGKSTRILNRTTMQEMVTPVGVGPYA
VGFEILKRGEGWYFRKWGSSLGYKSQLLAHRSKGYGVVIMLSGNSEPIINELVERVARAYRWDSLDQPIPQR
>Mature_392_residues
MKAYLIGIVAALMLTPEIGLAQDAADMIRGIESSQLASRQGDPGSLTMEQLLAFYHVSSLSMAVIHDFRIHWAKSWGMAD
ARAGTPATNDTLYRAASISKPVAAMATLKAIQNGVFGLDQDVNTILKSWKFPESSYTERQPITLRALLSHTAGTGDGFGF
DGYEPGAKLPTVPQMLSGQPPANNGEVRLVRPPSTAYQYSGGGVMAAQLALTDAVGKPFETIADEWILRPIGMSKSTFAQ
PLPPDLERHAAREYADSGKAVGTQWSAFPQLAAAGLWSTPTDLAKFAIEVQNTLAGKSTRILNRTTMQEMVTPVGVGPYA
VGFEILKRGEGWYFRKWGSSLGYKSQLLAHRSKGYGVVIMLSGNSEPIINELVERVARAYRWDSLDQPIPQR

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=345, Percent_Identity=24.9275362318841, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17550934, Length=285, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.2.6

Molecular weight: Translated: 42505; Mature: 42505

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYLIGIVAALMLTPEIGLAQDAADMIRGIESSQLASRQGDPGSLTMEQLLAFYHVSSL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SMAVIHDFRIHWAKSWGMADARAGTPATNDTLYRAASISKPVAAMATLKAIQNGVFGLDQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
DVNTILKSWKFPESSYTERQPITLRALLSHTAGTGDGFGFDGYEPGAKLPTVPQMLSGQP
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
PANNGEVRLVRPPSTAYQYSGGGVMAAQLALTDAVGKPFETIADEWILRPIGMSKSTFAQ
CCCCCCEEEECCCCCCEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCC
PLPPDLERHAAREYADSGKAVGTQWSAFPQLAAAGLWSTPTDLAKFAIEVQNTLAGKSTR
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
ILNRTTMQEMVTPVGVGPYAVGFEILKRGEGWYFRKWGSSLGYKSQLLAHRSKGYGVVIM
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEHHCCCCCHHHHHHHHHCCCCEEEEE
LSGNSEPIINELVERVARAYRWDSLDQPIPQR
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKAYLIGIVAALMLTPEIGLAQDAADMIRGIESSQLASRQGDPGSLTMEQLLAFYHVSSL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SMAVIHDFRIHWAKSWGMADARAGTPATNDTLYRAASISKPVAAMATLKAIQNGVFGLDQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
DVNTILKSWKFPESSYTERQPITLRALLSHTAGTGDGFGFDGYEPGAKLPTVPQMLSGQP
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
PANNGEVRLVRPPSTAYQYSGGGVMAAQLALTDAVGKPFETIADEWILRPIGMSKSTFAQ
CCCCCCEEEECCCCCCEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHCCC
PLPPDLERHAAREYADSGKAVGTQWSAFPQLAAAGLWSTPTDLAKFAIEVQNTLAGKSTR
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
ILNRTTMQEMVTPVGVGPYAVGFEILKRGEGWYFRKWGSSLGYKSQLLAHRSKGYGVVIM
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEHHCCCCCHHHHHHHHHCCCCEEEEE
LSGNSEPIINELVERVARAYRWDSLDQPIPQR
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA