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The map label for this gene is ptsP [C]

Identifier: 116623553

GI number: 116623553

Start: 5652513

End: 5653742

Strand: Reverse

Name: ptsP [C]

Synonym: Acid_4463

Alternate gene names: 116623553

Gene position: 5653742-5652513 (Counterclockwise)

Preceding gene: 116623554

Following gene: 116623552

Centisome position: 56.73

GC content: 59.11

Gene sequence:

>1230_bases
GTGCCGGTCATGGAAGCCAAAAGCCAAGTTGAACTGTTGCACCAGATCAGCAACATTGTCAGTTCCAATCTCAGCCTGGA
GAAAATGCTTCAGGAGTTGATTGGTCTTGCGGTCGAAGTTACGGATTGCGATGCGTGCCTGGTCTACCTGCTGGACAGAC
ACCGCAAGGAAATCGTACTGCGCGCATCCAAGCTGCCGCACGCCAAGGAAATCGGCCATATCCGGATGAAGATGGGAGAG
GGCATCACCGGGTGGGTCGCGCAGAATAAGAGTGTGGTCGCGCTCGGCGCGAATGCCGCCGCGGATCCCCGCTTCAAGAG
TTTTCAAAAGCTGCCCGAGGATACCTATCAGGCATTCCTTTCGGTGCCGCTGGTGAACGCCGGCGAACTGATCGGTGTGA
TCAACATTCACCACGAGACCAAGCATCCTCACAGCCAGGATGAAGTGGCGCTGGTGTCATTCATGGGCGAACAGATGGGC
GGCGCGATCGCCAAGAGCCGGCTGGCCGAGCGCTCCGAACGCGCCACGCGCCGGATGGAGGCGCTGGCCGGGTTAGCCGA
AGGCATCAACGAGAAGAACTACCTGGATCGCATTTTGCAGACGATCGCGGAAATGGTGGCCGACAAGCTGGATTCTCCGG
TCTGCTCGATCATGCTGGTGGACGAGGAACGGCAGGAGCTGAACATCAGCGCGGCGCGCTGCTCTTCGGAGGATTACCTG
CACCGGATGCCGCTCAAGATCGAGGAATCGCTGATTGGCCGTGTGGTGCGCGAGCGGCAGCCGATTATGATTCCGAACGT
GCTCGAGGAAAAGCAGTACCGTTATCCGGAACTGGCGCGGAAGACTGGCCTCGCGTCGCTGCTCTCGGTGCCCATGTTTA
CGCGGGACACGGTGATCGGCACGATCAACATCTATACGCGGGAAGTGCATCAATTCGCCGAAGATGAAATCGACTTCGTG
AAGGTGGTGGCCAGCCAGGCGGCGATCGCGATCGAGAACGCGCGGCTGATGTCGGAGACTTTGGAGGCGAAGCGCGCGCT
CGAGACCCGCAAAGTAGTGGAGCGTGCCAAGGGTATCATGCAGCACAAGTACCACATTACCGAAGAGGACGCGTACTTGA
AGCTGCGCAACGAAAGCCGCCGCCTGCGGCGGCCGATGCGCGACCTTGCCGAAGCCATTATTTTGGCCGACGAATTGGAA
AAGCAGCGTCCGGCCAAACCCACGGTCTAA

Upstream 100 bases:

>100_bases
TCCGTTAACGCGGCACCTGATACCGCACATAGGAAATATTGATTGGACGTACCGGACCCCCACTCTTACACTCAAGGTTA
GAAAGAAAAGGGGAAACTCA

Downstream 100 bases:

>100_bases
ATTTCTCCTTTCGCACGAGTCATCCTCTCACCCGGTTTGGGCACGCCACTTGTGCGGGTCCCAGGCCGGGCTTTTTTTTG
CCCGTGTTACACTCCGGCGT

Product: putative GAF sensor protein

Products: pyruvate; proteinN-pros-phosphohistidine [C]

Alternate protein names: Phosphoenolpyruvate-Protein Phosphotransferase; GAF Sensor Protein; GAF Sensor Signal Transduction Histidine Kinase; Multi-Sensor Signal Transduction Histidine Kinase; Phytochrome Sensor Protein; GAF Domain-Containing Protein; PTSINtr With GAF Domain PtsP; Diguanylate Cyclase With GAF Sensor; Metal Dependent Phosphohydrolase; GAF Sensor-Containing Protein Serine Phosphatase; Diguanylate Cyclase; GAF Domain Protein; Serine Phosphatase; Sensor Protein; Signal Transduction Histidine Kinase; Sigma Factor SigB Regulation Protein RsbU; PAS/PAC Sensor Protein; Sensor Histidine Kinase; Two-Component Hybrid Sensor And Regulator; Adenylate/Guanylate Cyclase; Two Component System Response Regulator; Sensory Transcriptional Regulator; Adenylate/Guanylate Cyclase With GAF And PAS/PAC Sensors; PAS Sensor Protein; Transcriptional Regulator; Transcriptional Regulator CdaR; Sigma Factor Regulatory Protein; Response Regulator Receiver; Sensory Box Histidine Kinase; Adenylate Cyclase; Phosphotransferase System I PtsP; Response Regulator Receiver/ANTAR Domain-Containing Protein; Signal Transduction Protein; Two-Component System Response Regulator; Serine/Threonine Phosphatase; ANTAR Domain-Containing Protein; Signal Transduction Histidine Kinase With GAF Domain; Serine Phosphatase RsbU Regulator Of Sigma Subunit; PTS System I Transcriptional Regulator PtsP; GAF Sensor-Containing Adenylate/Guanylate Cyclase; Antar Domain Protein; ATPase Histidine Kinase- DNA Gyrase B- And; GGDEF Domain Family Protein

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPVMEAKSQVELLHQISNIVSSNLSLEKMLQELIGLAVEVTDCDACLVYLLDRHRKEIVLRASKLPHAKEIGHIRMKMGE
GITGWVAQNKSVVALGANAAADPRFKSFQKLPEDTYQAFLSVPLVNAGELIGVINIHHETKHPHSQDEVALVSFMGEQMG
GAIAKSRLAERSERATRRMEALAGLAEGINEKNYLDRILQTIAEMVADKLDSPVCSIMLVDEERQELNISAARCSSEDYL
HRMPLKIEESLIGRVVRERQPIMIPNVLEEKQYRYPELARKTGLASLLSVPMFTRDTVIGTINIYTREVHQFAEDEIDFV
KVVASQAAIAIENARLMSETLEAKRALETRKVVERAKGIMQHKYHITEEDAYLKLRNESRRLRRPMRDLAEAIILADELE
KQRPAKPTV

Sequences:

>Translated_409_residues
MPVMEAKSQVELLHQISNIVSSNLSLEKMLQELIGLAVEVTDCDACLVYLLDRHRKEIVLRASKLPHAKEIGHIRMKMGE
GITGWVAQNKSVVALGANAAADPRFKSFQKLPEDTYQAFLSVPLVNAGELIGVINIHHETKHPHSQDEVALVSFMGEQMG
GAIAKSRLAERSERATRRMEALAGLAEGINEKNYLDRILQTIAEMVADKLDSPVCSIMLVDEERQELNISAARCSSEDYL
HRMPLKIEESLIGRVVRERQPIMIPNVLEEKQYRYPELARKTGLASLLSVPMFTRDTVIGTINIYTREVHQFAEDEIDFV
KVVASQAAIAIENARLMSETLEAKRALETRKVVERAKGIMQHKYHITEEDAYLKLRNESRRLRRPMRDLAEAIILADELE
KQRPAKPTV
>Mature_408_residues
PVMEAKSQVELLHQISNIVSSNLSLEKMLQELIGLAVEVTDCDACLVYLLDRHRKEIVLRASKLPHAKEIGHIRMKMGEG
ITGWVAQNKSVVALGANAAADPRFKSFQKLPEDTYQAFLSVPLVNAGELIGVINIHHETKHPHSQDEVALVSFMGEQMGG
AIAKSRLAERSERATRRMEALAGLAEGINEKNYLDRILQTIAEMVADKLDSPVCSIMLVDEERQELNISAARCSSEDYLH
RMPLKIEESLIGRVVRERQPIMIPNVLEEKQYRYPELARKTGLASLLSVPMFTRDTVIGTINIYTREVHQFAEDEIDFVK
VVASQAAIAIENARLMSETLEAKRALETRKVVERAKGIMQHKYHITEEDAYLKLRNESRRLRRPMRDLAEAIILADELEK
QRPAKPTV

Specific function: Could Function In The Transcriptional Regulation Of Sigma-54 Dependent Operons In Conjunction With The Npr (Ptso) And Iiantr (Ptsn) Proteins Thereby Providing A Link Between Carbon And Nitrogen Assimilatory Pathways. [C]

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.3.9 [C]

Molecular weight: Translated: 46159; Mature: 46028

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50921 ANTAR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMEAKSQVELLHQISNIVSSNLSLEKMLQELIGLAVEVTDCDACLVYLLDRHRKEIVL
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHH
RASKLPHAKEIGHIRMKMGEGITGWVAQNKSVVALGANAAADPRFKSFQKLPEDTYQAFL
HHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHH
SVPLVNAGELIGVINIHHETKHPHSQDEVALVSFMGEQMGGAIAKSRLAERSERATRRME
HCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAGLAEGINEKNYLDRILQTIAEMVADKLDSPVCSIMLVDEERQELNISAARCSSEDYL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCHHHHCCCHHHH
HRMPLKIEESLIGRVVRERQPIMIPNVLEEKQYRYPELARKTGLASLLSVPMFTRDTVIG
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEE
TINIYTREVHQFAEDEIDFVKVVASQAAIAIENARLMSETLEAKRALETRKVVERAKGIM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHKYHITEEDAYLKLRNESRRLRRPMRDLAEAIILADELEKQRPAKPTV
HHHCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PVMEAKSQVELLHQISNIVSSNLSLEKMLQELIGLAVEVTDCDACLVYLLDRHRKEIVL
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHH
RASKLPHAKEIGHIRMKMGEGITGWVAQNKSVVALGANAAADPRFKSFQKLPEDTYQAFL
HHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHH
SVPLVNAGELIGVINIHHETKHPHSQDEVALVSFMGEQMGGAIAKSRLAERSERATRRME
HCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAGLAEGINEKNYLDRILQTIAEMVADKLDSPVCSIMLVDEERQELNISAARCSSEDYL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCHHHHCCCHHHH
HRMPLKIEESLIGRVVRERQPIMIPNVLEEKQYRYPELARKTGLASLLSVPMFTRDTVIG
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEE
TINIYTREVHQFAEDEIDFVKVVASQAAIAIENARLMSETLEAKRALETRKVVERAKGIM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHKYHITEEDAYLKLRNESRRLRRPMRDLAEAIILADELEKQRPAKPTV
HHHCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg2+; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0105 {histidine-containing} 0.195 {phosphoenolpyruvate}} [C]

Substrates: Phosphoenolpyruvate; protein histidine [C]

Specific reaction: Phosphoenolpyruvate + protein histidine = pyruvate + proteinN-pros-phosphohistidine [C]

General reaction: Phospho group transfer [C]

Inhibitor: 2-Hydroxy -3-butenoic acid [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA