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The map label for this gene is yesM [H]

Identifier: 116623394

GI number: 116623394

Start: 5449569

End: 5450702

Strand: Direct

Name: yesM [H]

Synonym: Acid_4303

Alternate gene names: 116623394

Gene position: 5449569-5450702 (Clockwise)

Preceding gene: 116623392

Following gene: 116623395

Centisome position: 54.68

GC content: 60.85

Gene sequence:

>1134_bases
ATGTCACAACCTCCCGATTCCGCGATCCGCCGGTGGCTGGCGTATTGGCTCGCCTGGACCACGGCGGGGCTCTTCTACAT
CACGCAGGACTTCATGACGCGGCTGTCTCGCAACGAGTCGATCCCTTGGCGGAATGTGGTGATCGGCTGGATGACCGCGA
TGTACATTTGCGCGCTATTCACACCGGCGATCCTATGGTTCGGTCGCCGCTGGGCTGTGGATGCGGGCGACCGCCGGCAA
CACATTGGAATCCACCTCGGCGCCTCAGTGGTCCTCTCGCTGGTATCGACCGCTCTGGAAGTGCCGGTGCTAGGCGCGAT
TGGATTGCTGCCGCCTTTCGGGCATACAACCTCGTTCGCCGCGGATTTTTGGCATCTTTTACCATACGACCTGCACGGAG
GCATAGTCCGATATTGGGCGGTCATCGCAGTGCAGGCGCTCTTCCGGTCGAATCGGGAGGCTCGCCGGCGCGAGCGCGAA
GCCCTGGAGCTGAAGGTTCAGTCTTCCCAACTCGCTGAGCAATTAACAGCATCGCAATTGAACGCCCTGAAGATGCAAAT
GCACCCGCACTTCCTGTTCAATACGCTCAGCGCCATTATGGTGTTAGTGCGCCAGGGGAAGGGACACGAGGCCGAAACGA
TGCTCAGCCGCCTGGGCGATCTGCTGCGGCATACGCTGGATGACGTGGAAGCCCAGGAGGTCCCGCTGTGGCGCGAACTC
GATTTTCTGCGGTTGTATCTTTCGATCGAGCAGGTTCGCTTTGAGGACCGGCTGCATGTCCGGATCGATGCCGGGCCGGA
GGTTTCGGAGGCGCTCGTTCCCCACATGGTTCTTCAGCCGATCGTGGAGAACGCGGTACGACACGGCTTGGGGCAGAGCG
AGGAGCCCGTCCTGATCCACGTCAGCATCTCGAGAGTCAACGGCCAGCTCTCACTTACCGTCCAAGATGACGGGCCGGGA
TGTCCTGATCGCGTATTCAACGGTAAAGGCATCGGACTCACCAACACGAGGAATCGCCTGAAGCGGCTTTACGGCGCGGA
GGCCACGTTCCTGGCCGAGAATCGGCTTCCCCGAGGAGTGCAGGTGACTATGAGCCTTCCCTTCCGCGAGGAGCGGGTGG
GGGATCAGGAATGA

Upstream 100 bases:

>100_bases
CGCTGGTGGCTCCGCGACGATCACCGGTCAATGAAATCGCGCGGTTGATCAATCGCGGCTTTTCTGCCGGCCGGATCCGT
AGAAGAATGGAAAGAGCGCG

Downstream 100 bases:

>100_bases
GCTTGAAGGTTCTGATTGTGGACGACGAACCGCTCGCTCGCGAGGGCATCAAACTAATGCTGGGCGGCGATTCTCTGGTG
ATGGAAGCCAGAAATGGAAG

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSQPPDSAIRRWLAYWLAWTTAGLFYITQDFMTRLSRNESIPWRNVVIGWMTAMYICALFTPAILWFGRRWAVDAGDRRQ
HIGIHLGASVVLSLVSTALEVPVLGAIGLLPPFGHTTSFAADFWHLLPYDLHGGIVRYWAVIAVQALFRSNREARRRERE
ALELKVQSSQLAEQLTASQLNALKMQMHPHFLFNTLSAIMVLVRQGKGHEAETMLSRLGDLLRHTLDDVEAQEVPLWREL
DFLRLYLSIEQVRFEDRLHVRIDAGPEVSEALVPHMVLQPIVENAVRHGLGQSEEPVLIHVSISRVNGQLSLTVQDDGPG
CPDRVFNGKGIGLTNTRNRLKRLYGAEATFLAENRLPRGVQVTMSLPFREERVGDQE

Sequences:

>Translated_377_residues
MSQPPDSAIRRWLAYWLAWTTAGLFYITQDFMTRLSRNESIPWRNVVIGWMTAMYICALFTPAILWFGRRWAVDAGDRRQ
HIGIHLGASVVLSLVSTALEVPVLGAIGLLPPFGHTTSFAADFWHLLPYDLHGGIVRYWAVIAVQALFRSNREARRRERE
ALELKVQSSQLAEQLTASQLNALKMQMHPHFLFNTLSAIMVLVRQGKGHEAETMLSRLGDLLRHTLDDVEAQEVPLWREL
DFLRLYLSIEQVRFEDRLHVRIDAGPEVSEALVPHMVLQPIVENAVRHGLGQSEEPVLIHVSISRVNGQLSLTVQDDGPG
CPDRVFNGKGIGLTNTRNRLKRLYGAEATFLAENRLPRGVQVTMSLPFREERVGDQE
>Mature_376_residues
SQPPDSAIRRWLAYWLAWTTAGLFYITQDFMTRLSRNESIPWRNVVIGWMTAMYICALFTPAILWFGRRWAVDAGDRRQH
IGIHLGASVVLSLVSTALEVPVLGAIGLLPPFGHTTSFAADFWHLLPYDLHGGIVRYWAVIAVQALFRSNREARRREREA
LELKVQSSQLAEQLTASQLNALKMQMHPHFLFNTLSAIMVLVRQGKGHEAETMLSRLGDLLRHTLDDVEAQEVPLWRELD
FLRLYLSIEQVRFEDRLHVRIDAGPEVSEALVPHMVLQPIVENAVRHGLGQSEEPVLIHVSISRVNGQLSLTVQDDGPGC
PDRVFNGKGIGLTNTRNRLKRLYGAEATFLAENRLPRGVQVTMSLPFREERVGDQE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=218, Percent_Identity=30.2752293577982, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788446, Length=197, Percent_Identity=31.9796954314721, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42723; Mature: 42592

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPPDSAIRRWLAYWLAWTTAGLFYITQDFMTRLSRNESIPWRNVVIGWMTAMYICALF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TPAILWFGRRWAVDAGDRRQHIGIHLGASVVLSLVSTALEVPVLGAIGLLPPFGHTTSFA
HHHHHHHCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ADFWHLLPYDLHGGIVRYWAVIAVQALFRSNREARRREREALELKVQSSQLAEQLTASQL
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALKMQMHPHFLFNTLSAIMVLVRQGKGHEAETMLSRLGDLLRHTLDDVEAQEVPLWREL
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHH
DFLRLYLSIEQVRFEDRLHVRIDAGPEVSEALVPHMVLQPIVENAVRHGLGQSEEPVLIH
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VSISRVNGQLSLTVQDDGPGCPDRVFNGKGIGLTNTRNRLKRLYGAEATFLAENRLPRGV
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCE
QVTMSLPFREERVGDQE
EEEEECCCHHHCCCCCC
>Mature Secondary Structure 
SQPPDSAIRRWLAYWLAWTTAGLFYITQDFMTRLSRNESIPWRNVVIGWMTAMYICALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TPAILWFGRRWAVDAGDRRQHIGIHLGASVVLSLVSTALEVPVLGAIGLLPPFGHTTSFA
HHHHHHHCCCEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ADFWHLLPYDLHGGIVRYWAVIAVQALFRSNREARRREREALELKVQSSQLAEQLTASQL
HHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALKMQMHPHFLFNTLSAIMVLVRQGKGHEAETMLSRLGDLLRHTLDDVEAQEVPLWREL
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHH
DFLRLYLSIEQVRFEDRLHVRIDAGPEVSEALVPHMVLQPIVENAVRHGLGQSEEPVLIH
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VSISRVNGQLSLTVQDDGPGCPDRVFNGKGIGLTNTRNRLKRLYGAEATFLAENRLPRGV
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCE
QVTMSLPFREERVGDQE
EEEEECCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]