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The map label for this gene is yfdE [H]

Identifier: 116623372

GI number: 116623372

Start: 5423985

End: 5425190

Strand: Direct

Name: yfdE [H]

Synonym: Acid_4281

Alternate gene names: 116623372

Gene position: 5423985-5425190 (Clockwise)

Preceding gene: 116623368

Following gene: 116623379

Centisome position: 54.43

GC content: 67.0

Gene sequence:

>1206_bases
GTGCATTTGAAGCCTCTGGATGACATTCGAGTTCTGGATTTTTCGCACGCGCTTGCCGGCCCTTACTGCACGATGCTGCT
GGCGGAGTACGGGGCCGACGTTTATAAGCTGGAATCGCGCGCGGGCGACATGGGACGCGGGTGGGGGCCGCCGTTCGCGG
GCGGGGTGGCGAGTTTCTTTTTGGGATTGAATCGCGGCAAGCGCGGGATCTCCTTCGACCTGAAGCATGCGGAGGGGCTG
GAGCTTTGCCTGAGGCTGATCGACCGGATGGACGTGCTGATCGAGAACTTCCGTCCGGGCGCGATGGACCGGCTCGGACT
GGGGTACGAAGCCCTGCACGCGCGGCATCCGGCGCTGGTCTACTGCTCGATTTCGGGCTACGGGCAGGACGGTCCTTCGC
GGGACGAAGCGGCGATGGACCTGGTGGTGCAAGGTTCGAGCGGGCTGCTGAGCATCACGGGCACGGCCGATGGCGAATCG
GTGCGGTGCGGGTACGGGGTGACGGACGTGACGGCGGGACAGTTCGCGATTATCGGCATCCTGCTGGCGCTGCGGGCGCG
CGAGCGGACCGGCCGCGGGCAGTTCATCGACGTTTCGATGCTGGACGGAATGATTTCCACGATGAGCTCGAATTACATGA
CGTACCTGGGATCGGGCCGCGTGCCGGAACCGATGGGGACGGCATTCCCGACGGTGGTGCCGTACCGGGTGTTCCACACG
CTGGACCGTCCGATTGCGATCGCGGTGGGAAGCGAGAAGCTGTGGTCGGCGTTCTGCCGCGCGATCGAACGTCCCGACCT
GGAGCGGCACGCGGATTACGATACGAATGCCGGGCGGATCCGCAACCGGGCGGCGCTGGAACCGCTGCTGGACGAGGTCT
TCAAGATGCGCGCGGTGGGCGATTGGATGGAGCGGCTGCAGGCGGCGGGAATTCCTTCGTCGCCGGTGCGCACTTTCGAA
GACGTGGTGGAGCACGAGCAAGCGGCGGTGCGGGAGATGTTCCCGACGCTGCAGCACCCCACGGCCGGAGCGCATCGCGT
GACGGGGACGCCTGTGAAGCTTTCGGAAACGCCCGGACGTCCCGGGCTGCCGGCTCCACTGCTGGGGCAGCATACGCGGG
AGACGCTGGCGGAGTTGCTGGGCCTGGGCGCGGCGGAGGTGGACGGCCTGGCGGCGCGCGGCGTGGTGTACGAAGCGGCC
GGCTAG

Upstream 100 bases:

>100_bases
TGAGAAAAGGCCTTTAGATCGCTCCCTGACGGTCGCGGTTCGCGGTGAGGCCGGTGCTGGCGAGGGCAGGTGGCGTTTTG
GGGGGCGGTAGAATGGCCAA

Downstream 100 bases:

>100_bases
CTCGCAGTCAGGAAGCTATCGCGATCGCCGGGGCCGGGTATGGCGCCGACCTGGCGCAACAATCCCAACTGGTCATAGCA
GTTCCAGCCCTCGACGATTT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHLKPLDDIRVLDFSHALAGPYCTMLLAEYGADVYKLESRAGDMGRGWGPPFAGGVASFFLGLNRGKRGISFDLKHAEGL
ELCLRLIDRMDVLIENFRPGAMDRLGLGYEALHARHPALVYCSISGYGQDGPSRDEAAMDLVVQGSSGLLSITGTADGES
VRCGYGVTDVTAGQFAIIGILLALRARERTGRGQFIDVSMLDGMISTMSSNYMTYLGSGRVPEPMGTAFPTVVPYRVFHT
LDRPIAIAVGSEKLWSAFCRAIERPDLERHADYDTNAGRIRNRAALEPLLDEVFKMRAVGDWMERLQAAGIPSSPVRTFE
DVVEHEQAAVREMFPTLQHPTAGAHRVTGTPVKLSETPGRPGLPAPLLGQHTRETLAELLGLGAAEVDGLAARGVVYEAA
G

Sequences:

>Translated_401_residues
MHLKPLDDIRVLDFSHALAGPYCTMLLAEYGADVYKLESRAGDMGRGWGPPFAGGVASFFLGLNRGKRGISFDLKHAEGL
ELCLRLIDRMDVLIENFRPGAMDRLGLGYEALHARHPALVYCSISGYGQDGPSRDEAAMDLVVQGSSGLLSITGTADGES
VRCGYGVTDVTAGQFAIIGILLALRARERTGRGQFIDVSMLDGMISTMSSNYMTYLGSGRVPEPMGTAFPTVVPYRVFHT
LDRPIAIAVGSEKLWSAFCRAIERPDLERHADYDTNAGRIRNRAALEPLLDEVFKMRAVGDWMERLQAAGIPSSPVRTFE
DVVEHEQAAVREMFPTLQHPTAGAHRVTGTPVKLSETPGRPGLPAPLLGQHTRETLAELLGLGAAEVDGLAARGVVYEAA
G
>Mature_401_residues
MHLKPLDDIRVLDFSHALAGPYCTMLLAEYGADVYKLESRAGDMGRGWGPPFAGGVASFFLGLNRGKRGISFDLKHAEGL
ELCLRLIDRMDVLIENFRPGAMDRLGLGYEALHARHPALVYCSISGYGQDGPSRDEAAMDLVVQGSSGLLSITGTADGES
VRCGYGVTDVTAGQFAIIGILLALRARERTGRGQFIDVSMLDGMISTMSSNYMTYLGSGRVPEPMGTAFPTVVPYRVFHT
LDRPIAIAVGSEKLWSAFCRAIERPDLERHADYDTNAGRIRNRAALEPLLDEVFKMRAVGDWMERLQAAGIPSSPVRTFE
DVVEHEQAAVREMFPTLQHPTAGAHRVTGTPVKLSETPGRPGLPAPLLGQHTRETLAELLGLGAAEVDGLAARGVVYEAA
G

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=396, Percent_Identity=35.1010101010101, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI300863124, Length=422, Percent_Identity=33.4123222748815, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI13376042, Length=422, Percent_Identity=30.3317535545024, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI300863126, Length=396, Percent_Identity=31.3131313131313, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI266456254, Length=403, Percent_Identity=29.0322580645161, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI42794625, Length=403, Percent_Identity=29.0322580645161, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI266458393, Length=206, Percent_Identity=36.8932038834951, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI266458397, Length=206, Percent_Identity=36.8932038834951, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI42822893, Length=146, Percent_Identity=36.986301369863, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI266458395, Length=146, Percent_Identity=36.986301369863, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87082093, Length=377, Percent_Identity=33.42175066313, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788717, Length=402, Percent_Identity=30.8457711442786, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786222, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32564160, Length=334, Percent_Identity=25.4491017964072, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI115535051, Length=333, Percent_Identity=26.1261261261261, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648431, Length=395, Percent_Identity=38.9873417721519, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24585488, Length=368, Percent_Identity=27.7173913043478, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43325; Mature: 43325

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLKPLDDIRVLDFSHALAGPYCTMLLAEYGADVYKLESRAGDMGRGWGPPFAGGVASFF
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCHHHHHHHHH
LGLNRGKRGISFDLKHAEGLELCLRLIDRMDVLIENFRPGAMDRLGLGYEALHARHPALV
HHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCEEE
YCSISGYGQDGPSRDEAAMDLVVQGSSGLLSITGTADGESVRCGYGVTDVTAGQFAIIGI
EEEECCCCCCCCCCHHHHEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHH
LLALRARERTGRGQFIDVSMLDGMISTMSSNYMTYLGSGRVPEPMGTAFPTVVPYRVFHT
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
LDRPIAIAVGSEKLWSAFCRAIERPDLERHADYDTNAGRIRNRAALEPLLDEVFKMRAVG
CCCCEEEEECCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DWMERLQAAGIPSSPVRTFEDVVEHEQAAVREMFPTLQHPTAGAHRVTGTPVKLSETPGR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCC
PGLPAPLLGQHTRETLAELLGLGAAEVDGLAARGVVYEAAG
CCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHCCEEEECCC
>Mature Secondary Structure
MHLKPLDDIRVLDFSHALAGPYCTMLLAEYGADVYKLESRAGDMGRGWGPPFAGGVASFF
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCCCCCHHHHHHHHH
LGLNRGKRGISFDLKHAEGLELCLRLIDRMDVLIENFRPGAMDRLGLGYEALHARHPALV
HHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCEEE
YCSISGYGQDGPSRDEAAMDLVVQGSSGLLSITGTADGESVRCGYGVTDVTAGQFAIIGI
EEEECCCCCCCCCCHHHHEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHH
LLALRARERTGRGQFIDVSMLDGMISTMSSNYMTYLGSGRVPEPMGTAFPTVVPYRVFHT
HHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
LDRPIAIAVGSEKLWSAFCRAIERPDLERHADYDTNAGRIRNRAALEPLLDEVFKMRAVG
CCCCEEEEECCHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DWMERLQAAGIPSSPVRTFEDVVEHEQAAVREMFPTLQHPTAGAHRVTGTPVKLSETPGR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCC
PGLPAPLLGQHTRETLAELLGLGAAEVDGLAARGVVYEAAG
CCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]