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The map label for this gene is macB1 [H]

Identifier: 116623359

GI number: 116623359

Start: 5401674

End: 5404196

Strand: Reverse

Name: macB1 [H]

Synonym: Acid_4268

Alternate gene names: 116623359

Gene position: 5404196-5401674 (Counterclockwise)

Preceding gene: 116623360

Following gene: 116623356

Centisome position: 54.23

GC content: 64.61

Gene sequence:

>2523_bases
ATGCTATCAGACATTCGGTATGCGCTGCGGATTCTGCGGAAGAATCGGGGATTTGCCGTGGTGGCGGTGTTGTCGCTGGC
ACTGGGGATTGGGGCGAATACCGCGATTTTCACGCTGATCGACAATGTGATGTTGCGCGCACTTCCGGTGCGGGCTCCCG
AGCGGCTGGCGGTGCTGGCCTCGAATCCCGCGAACCCAAGCGTGTCGTTCAACTATCCCGATTACGTTTACGTGCGGGAC
CATAACCAGTCGTACGCGGGCGTACTGGCGTCGAGCGAAGGGTCCACGGCGGCGTTTTCGGTTCCGGGCGAGAAGGGGAC
GTCGGCGGAGGTGGTGGCGACGGCGCGGGTGTCGGGGAACTACTTCGACGTGCTCGGAGTGGGCGCGGCGATCGGGCGGC
TGCTGACGCCGGCGGACAACGTCACCGAAGGCGCGCATCCGGTGACGGTGATCTCGTGGGAGATGTGGCAGCGGCGATTC
GGGGGCGAGAACGGCGTTTTGGGGCGCTCGATCACGCTCAATGGAGTACCGTTCCAGGTGATCGGCGTGGCGGCGCGCGG
CTTTCACGGGACGCAGGTGGGAACGGTCAACGACCTCTACGTGCCGATCATGATGATGCCGACGCTGAATCCGCCGGCGC
GCGGCTGGAATTCGCGGCACTGGTGGTGGCTTACGGTCATCGCGCGAATGAAGCCCGGGTCAACGCTGAATTCCGCGAGT
TCCGAGTTGAACGTGCTGTGGCAGCAGATTCTGAAGGCCGACTCGGAGTACAAACCGCCGCCCGCGTGGGACAAAGAGGC
GCCGCTGCGCGACCGGATGGTGGTGATTCCGGGGAGTGCGGGATGGTCTTACTTCCGCGTGCAGTTTTCCAAGCCCCTTA
CGGTGCTGATGATCGTGGTGGGACTGGTGCTCCTGATCGCGTGCGCGAACGTGGCAAACCTGCTGTTGGCGCGCGCGGCC
GGAAGACAGAAGGAGATCGCGGTACGGCTGGCGATCGGCGCGGGCCGGGGACGGCTGGTTTCGCAACTGGTGGTGGAGAC
GGTGGTGGTGTCGTTGTTGGGAGGCATTAGCGGGCTGGTGTTCGCGTGGTGGGGAATCCGGGTGCTGATGGGGCTGCTGC
CAAAGCGGGCGATTCCGATCGATCTGAATTTGAGCCCTGACTGGCGCGTGCTGGGGTTCGCATTTCTGGCGAGCCTGGTG
ACGGGACTGTTGTGCGGGCTGGTGCCGGCGCTGCAATCGACGCGGCCGAACCTGGTGACGGCGTTGAAGAACGAGACGGC
GGTGGCGCGGCGCAGCCGCTTCGATTTGCGGCGGCTGCTGGTAGTGGCGCAGGTGGCGCTCTCGCTGTTGCTGCTGGCGG
GCGCGGGACTATTTGTGCGCAGCTTGAACAACCTGGAGAAACTGGATCCGGGGTTCGTGCGCGAGCGAGTGCTGCTGGTG
AGCGTGAATCCGCAGAACAGCGGATACCTGGGTAAGCGGCTGCGCGATTATTACGAGCGGCTGCTGGCGAAGACGATGGA
CAACCCGGAGGTGCGCACGGCGAGCCTGGCGAACATCACGCCGCTTTCGAATTCGCGGTGGAACAACGGCGTCTCGTTCA
TCGATTACAAGTTCGGCCCCCAGGAGCGGAACTCCGTCGATATGAATGCGGTGACGCCGCATTTCTTTGAGACGCTGGGG
ATCCCGCTGGTGGCCGGGCGCGATTTTACCGAGCAGGATAACCCCACGTTCACGCCGGACGGACGCGCGGCGCCGGATCC
GAAATTGAAGTCGCAGGGGCCGCGGGTGGCGATTGTGAATGAGAGCTTCGCGAAGAAGTTCTTCCCCAAACGGTCGGCGA
TCGGCGAGCGTGTGTGCCGCGATAAGGAATTCAAGATGGAAGAGTCGCTGGAGATCGTCGGAGTGGTGAAGGATGCGCGG
TATTTCGGACTGCGCAAGGCGACGGAGCCGATGATCTATATTCCGAGCTGGCGCGACGGTGCGGGAGGGAAAACGCTTTG
CGTGCGCACGACCGGCGATCCCGCGCGGGTAGTGGCGGCGATCCGGCGGGAGGCGGCGGCGATGGATCCGACGATTCCGG
TGACGCAGACGCTGACGCTGGCCGATCAATTCGACAACAACATCGCGCAGGAACGGATTTTGACGATGCTGTGCGGGTTC
TTCGGAATCCTGGCGGTGCTCTTGGCGGCGATCGGATTGTACGGCGTGATGGCGCACGCGGTGGCTCGGCGGGTCCGGGA
GATCGGGATCCGGATGGCTCTGGGGGCGCAGGCTCCCGAGGTGCGGTGGCTGATATTGCGGGAGACGGCGTGGATGGTGG
GCTGCGGCGCGGCGATCGGGCTGCCGGCGGCATACTTCACGACGCGGCTGGTGGAGAGCTTCCTGTTCGGACTGACGCCG
CAGGATCCGGTGACGCTGGCGCTATCGACGGCTGCGCTGCTGGGGGTGACGGCGATCGCTGGGTATATTCCGGCGCGGCG
GGCGACGCGGGTGGATCCGATGATCGCGCTGCGGTACGAGTGA

Upstream 100 bases:

>100_bases
GCGGGTGTTTGCGGGCTGCGAGCAGACAAAGCAGTGTAATACAACGGTGATGCCAACGAAATGAGGGGGGGCGGCGTCTA
ATGTCTGATCGGGAGGTGGC

Downstream 100 bases:

>100_bases
GGGAAAGACTGATTAGTGCGCCGGCTGAAAGCCGGCGGCAGCCAGGATTGGCTGCCCCACAGGATGAAAAGCTGATTAGT
CGACAGGCCAAGGAGGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 840; Mature: 840

Protein sequence:

>840_residues
MLSDIRYALRILRKNRGFAVVAVLSLALGIGANTAIFTLIDNVMLRALPVRAPERLAVLASNPANPSVSFNYPDYVYVRD
HNQSYAGVLASSEGSTAAFSVPGEKGTSAEVVATARVSGNYFDVLGVGAAIGRLLTPADNVTEGAHPVTVISWEMWQRRF
GGENGVLGRSITLNGVPFQVIGVAARGFHGTQVGTVNDLYVPIMMMPTLNPPARGWNSRHWWWLTVIARMKPGSTLNSAS
SELNVLWQQILKADSEYKPPPAWDKEAPLRDRMVVIPGSAGWSYFRVQFSKPLTVLMIVVGLVLLIACANVANLLLARAA
GRQKEIAVRLAIGAGRGRLVSQLVVETVVVSLLGGISGLVFAWWGIRVLMGLLPKRAIPIDLNLSPDWRVLGFAFLASLV
TGLLCGLVPALQSTRPNLVTALKNETAVARRSRFDLRRLLVVAQVALSLLLLAGAGLFVRSLNNLEKLDPGFVRERVLLV
SVNPQNSGYLGKRLRDYYERLLAKTMDNPEVRTASLANITPLSNSRWNNGVSFIDYKFGPQERNSVDMNAVTPHFFETLG
IPLVAGRDFTEQDNPTFTPDGRAAPDPKLKSQGPRVAIVNESFAKKFFPKRSAIGERVCRDKEFKMEESLEIVGVVKDAR
YFGLRKATEPMIYIPSWRDGAGGKTLCVRTTGDPARVVAAIRREAAAMDPTIPVTQTLTLADQFDNNIAQERILTMLCGF
FGILAVLLAAIGLYGVMAHAVARRVREIGIRMALGAQAPEVRWLILRETAWMVGCGAAIGLPAAYFTTRLVESFLFGLTP
QDPVTLALSTAALLGVTAIAGYIPARRATRVDPMIALRYE

Sequences:

>Translated_840_residues
MLSDIRYALRILRKNRGFAVVAVLSLALGIGANTAIFTLIDNVMLRALPVRAPERLAVLASNPANPSVSFNYPDYVYVRD
HNQSYAGVLASSEGSTAAFSVPGEKGTSAEVVATARVSGNYFDVLGVGAAIGRLLTPADNVTEGAHPVTVISWEMWQRRF
GGENGVLGRSITLNGVPFQVIGVAARGFHGTQVGTVNDLYVPIMMMPTLNPPARGWNSRHWWWLTVIARMKPGSTLNSAS
SELNVLWQQILKADSEYKPPPAWDKEAPLRDRMVVIPGSAGWSYFRVQFSKPLTVLMIVVGLVLLIACANVANLLLARAA
GRQKEIAVRLAIGAGRGRLVSQLVVETVVVSLLGGISGLVFAWWGIRVLMGLLPKRAIPIDLNLSPDWRVLGFAFLASLV
TGLLCGLVPALQSTRPNLVTALKNETAVARRSRFDLRRLLVVAQVALSLLLLAGAGLFVRSLNNLEKLDPGFVRERVLLV
SVNPQNSGYLGKRLRDYYERLLAKTMDNPEVRTASLANITPLSNSRWNNGVSFIDYKFGPQERNSVDMNAVTPHFFETLG
IPLVAGRDFTEQDNPTFTPDGRAAPDPKLKSQGPRVAIVNESFAKKFFPKRSAIGERVCRDKEFKMEESLEIVGVVKDAR
YFGLRKATEPMIYIPSWRDGAGGKTLCVRTTGDPARVVAAIRREAAAMDPTIPVTQTLTLADQFDNNIAQERILTMLCGF
FGILAVLLAAIGLYGVMAHAVARRVREIGIRMALGAQAPEVRWLILRETAWMVGCGAAIGLPAAYFTTRLVESFLFGLTP
QDPVTLALSTAALLGVTAIAGYIPARRATRVDPMIALRYE
>Mature_840_residues
MLSDIRYALRILRKNRGFAVVAVLSLALGIGANTAIFTLIDNVMLRALPVRAPERLAVLASNPANPSVSFNYPDYVYVRD
HNQSYAGVLASSEGSTAAFSVPGEKGTSAEVVATARVSGNYFDVLGVGAAIGRLLTPADNVTEGAHPVTVISWEMWQRRF
GGENGVLGRSITLNGVPFQVIGVAARGFHGTQVGTVNDLYVPIMMMPTLNPPARGWNSRHWWWLTVIARMKPGSTLNSAS
SELNVLWQQILKADSEYKPPPAWDKEAPLRDRMVVIPGSAGWSYFRVQFSKPLTVLMIVVGLVLLIACANVANLLLARAA
GRQKEIAVRLAIGAGRGRLVSQLVVETVVVSLLGGISGLVFAWWGIRVLMGLLPKRAIPIDLNLSPDWRVLGFAFLASLV
TGLLCGLVPALQSTRPNLVTALKNETAVARRSRFDLRRLLVVAQVALSLLLLAGAGLFVRSLNNLEKLDPGFVRERVLLV
SVNPQNSGYLGKRLRDYYERLLAKTMDNPEVRTASLANITPLSNSRWNNGVSFIDYKFGPQERNSVDMNAVTPHFFETLG
IPLVAGRDFTEQDNPTFTPDGRAAPDPKLKSQGPRVAIVNESFAKKFFPKRSAIGERVCRDKEFKMEESLEIVGVVKDAR
YFGLRKATEPMIYIPSWRDGAGGKTLCVRTTGDPARVVAAIRREAAAMDPTIPVTQTLTLADQFDNNIAQERILTMLCGF
FGILAVLLAAIGLYGVMAHAVARRVREIGIRMALGAQAPEVRWLILRETAWMVGCGAAIGLPAAYFTTRLVESFLFGLTP
QDPVTLALSTAALLGVTAIAGYIPARRATRVDPMIALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=321, Percent_Identity=26.1682242990654, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 91476; Mature: 91476

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDIRYALRILRKNRGFAVVAVLSLALGIGANTAIFTLIDNVMLRALPVRAPERLAVLA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
SNPANPSVSFNYPDYVYVRDHNQSYAGVLASSEGSTAAFSVPGEKGTSAEVVATARVSGN
CCCCCCCEEECCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCC
YFDVLGVGAAIGRLLTPADNVTEGAHPVTVISWEMWQRRFGGENGVLGRSITLNGVPFQV
EEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCEEEECCCCEEE
IGVAARGFHGTQVGTVNDLYVPIMMMPTLNPPARGWNSRHWWWLTVIARMKPGSTLNSAS
EEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHH
SELNVLWQQILKADSEYKPPPAWDKEAPLRDRMVVIPGSAGWSYFRVQFSKPLTVLMIVV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHH
GLVLLIACANVANLLLARAAGRQKEIAVRLAIGAGRGRLVSQLVVETVVVSLLGGISGLV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FAWWGIRVLMGLLPKRAIPIDLNLSPDWRVLGFAFLASLVTGLLCGLVPALQSTRPNLVT
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALKNETAVARRSRFDLRRLLVVAQVALSLLLLAGAGLFVRSLNNLEKLDPGFVRERVLLV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCEEEEE
SVNPQNSGYLGKRLRDYYERLLAKTMDNPEVRTASLANITPLSNSRWNNGVSFIDYKFGP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC
QERNSVDMNAVTPHFFETLGIPLVAGRDFTEQDNPTFTPDGRAAPDPKLKSQGPRVAIVN
CCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
ESFAKKFFPKRSAIGERVCRDKEFKMEESLEIVGVVKDARYFGLRKATEPMIYIPSWRDG
HHHHHHHCCCHHHHHHHHHCCCCCCHHHCCEEEEEEHHHHHHCCHHCCCCEEEECCCCCC
AGGKTLCVRTTGDPARVVAAIRREAAAMDPTIPVTQTLTLADQFDNNIAQERILTMLCGF
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHCCHHHHHHHHHHHHHH
FGILAVLLAAIGLYGVMAHAVARRVREIGIRMALGAQAPEVRWLILRETAWMVGCGAAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCEEEEEEECCHHHEECCHHHC
LPAAYFTTRLVESFLFGLTPQDPVTLALSTAALLGVTAIAGYIPARRATRVDPMIALRYE
CCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MLSDIRYALRILRKNRGFAVVAVLSLALGIGANTAIFTLIDNVMLRALPVRAPERLAVLA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
SNPANPSVSFNYPDYVYVRDHNQSYAGVLASSEGSTAAFSVPGEKGTSAEVVATARVSGN
CCCCCCCEEECCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCC
YFDVLGVGAAIGRLLTPADNVTEGAHPVTVISWEMWQRRFGGENGVLGRSITLNGVPFQV
EEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCEEEECCCCEEE
IGVAARGFHGTQVGTVNDLYVPIMMMPTLNPPARGWNSRHWWWLTVIARMKPGSTLNSAS
EEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHH
SELNVLWQQILKADSEYKPPPAWDKEAPLRDRMVVIPGSAGWSYFRVQFSKPLTVLMIVV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHH
GLVLLIACANVANLLLARAAGRQKEIAVRLAIGAGRGRLVSQLVVETVVVSLLGGISGLV
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FAWWGIRVLMGLLPKRAIPIDLNLSPDWRVLGFAFLASLVTGLLCGLVPALQSTRPNLVT
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALKNETAVARRSRFDLRRLLVVAQVALSLLLLAGAGLFVRSLNNLEKLDPGFVRERVLLV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCEEEEE
SVNPQNSGYLGKRLRDYYERLLAKTMDNPEVRTASLANITPLSNSRWNNGVSFIDYKFGP
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC
QERNSVDMNAVTPHFFETLGIPLVAGRDFTEQDNPTFTPDGRAAPDPKLKSQGPRVAIVN
CCCCCCCCCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
ESFAKKFFPKRSAIGERVCRDKEFKMEESLEIVGVVKDARYFGLRKATEPMIYIPSWRDG
HHHHHHHCCCHHHHHHHHHCCCCCCHHHCCEEEEEEHHHHHHCCHHCCCCEEEECCCCCC
AGGKTLCVRTTGDPARVVAAIRREAAAMDPTIPVTQTLTLADQFDNNIAQERILTMLCGF
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHCCHHHHHHHHHHHHHH
FGILAVLLAAIGLYGVMAHAVARRVREIGIRMALGAQAPEVRWLILRETAWMVGCGAAIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCEEEEEEECCHHHEECCHHHC
LPAAYFTTRLVESFLFGLTPQDPVTLALSTAALLGVTAIAGYIPARRATRVDPMIALRYE
CCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA