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The map label for this gene is macB [H]

Identifier: 116623358

GI number: 116623358

Start: 5399136

End: 5401571

Strand: Direct

Name: macB [H]

Synonym: Acid_4267

Alternate gene names: 116623358

Gene position: 5399136-5401571 (Clockwise)

Preceding gene: 116623357

Following gene: 116623366

Centisome position: 54.18

GC content: 66.42

Gene sequence:

>2436_bases
ATGTTCCAGGATCTTCGCTTCGGCTTCAAGCTTCTCTGGAAAGAGAAGGCCTTCACCGTCACCGCCCTGTTGACGCTGGC
ACTTTGCATCGGCGCCAACACCGCGATCTTCTCGGTGCTGCATGCCGTGATCCTCGCTCCCTTGCCCTTCCCGGAATCGG
ATCGCCTGGTCGCCATGGGGAATGTCTATCCCGGCGCCGGCATCGACAAGAGCATCCAGAACAGCATCCCCGATTACTAT
GACCGCCGCGGCATGACCGACGTCTTCGAATCCGTCGCCCTCTATATCGACGCAGGCTTCGATGCCGGAGCCGAAGGCTC
ACCGGTGCGCCTCAAGGCAGACCTGGTCACCCCCTCTTTCTTCCACGTCCTCCGCGCCTCGCCCTTGATGGGCCGCCTCT
TCACCGAGGACGATGCCGTTCTCGATAAGAACCAGTTCGTCATCCTCAGCTACGGCTTGTGGAAAGAGATGTTCGCCAAG
GACGCCGCCATCCTCGGCCGCGACGTGCGCCTGAGCGGAGTAAATTATCGCGTCGTCGGCGTCATGCCCGAAGCCTTCTC
CTTCCCCGGCCGCGAAGCGCGCCTCTGGGTTCCCCTCACGTGGACGCAGCGCCAGACTACCGACGATGGCCGCCACAGCA
ACAACTGGAACATGATCGCGCGCCTCCAGCCCGGCGCCACCGTGACCGCCGTCCGCCGCCGCGTCGATGCGCTCAATCGC
CACAATGTGGAAAACTCGGGAAAGCTCCGCAAAATCCTCGAGGCCGCGCGCTTCGCCACCAACATCACCACCCTCAAGGA
TGAACTCATCGGCGACGTTCGTCCCACCCTCGTCCTGCTGCAATGCGCCGTCGCCTTCGTGCTCCTCATCGGCTGCGTCA
ACGTCGCCAACCTTATGCTCGTCCGTTCCAGCATTCGCATGAAGGAGCTGGCGATTCGCTATAGCCTCGGAGCCGGCCGC
GCGCGCCTCGCCATGCAGCTGCTCATTGAGGCGATGGCGCTCGCTGCCATCGGCGGCCTCTGCGGCCTGCTCACCGGCGC
CGCCGGCATCCGCCTCCTGGAACTGGTCGGAACCGCCGATCTCCCGCGCGGCACATCCATCGCCATGGATGGCTCCGTGC
TCGCCTTTAGCGCCGCCATCGCCGTGCTCACCGGTCTGGTCTTCGGCAGCGTCCCCGTCTACCACCTCGTCCGTCGCGAC
CTCAACGCCGTCTTCCGCTCCACCGAGCGCACCGGCACCACCGAAAAGCGGACTCTCTGGACCCGCTCCGCCCTCGTCGT
CTGCCAGGTCTCGCTCGCCTTCGTCCTCCTGATCGGCAGCGGACTCCTAACCCTCAGCTTCGCCCGCCTGCTCGCCGTGG
ACCCGGGCTTCAGCGCGCAGAACGTCCAGACCGCGCAGTTTTCGCTCCCCCGCTCGCGCTACAAGGAAGACGTCCAGCTG
CGCAACTTCCTCGGCCCGTTGCTCGCGGATATCCGCGCAATTCCCGGCGTCACTGCCGCGGGCGCCACAGATTCCCTACC
CTTCGGCGGCGACGTCAACGCCAGCGCGCTCGCGGTCGAGGGCTATAGCGCCGCCGGCGGAGAGCTGCCCCCTGTCCCGA
ATTGGAGTCACATCGATGCCGGCTACCTGCCCGCCATGCAGATTCCCCTGCGCGCCGGCCGCTATTTCCAGGAGAGCGAT
ACCGCCGACTCTCCCAAGGTCGCACTCATCGATGAATTTCTCGCGCGCAAATACTGGCCCGCCGGCAAGGCCGTCGGCGG
CCACATCCGCGCCGGCATCGAGGCCAAGGACACCCCCTATACCGTGGACGGAGTCGTAGGCACGATCAAGCCCGGCGATC
TCGCCGACCAGAGTCCGCGCGGCGCCGTGTATTTCGATTACAAGCAGAGCCCCGCGCGCACGGTTCATGTCGTCGTGAAA
ACCGCCGCCGCCAATCAGCAGGCCGTCTCCGCCGTCCGCGCCTCGCTGCTCAAGGCCGATCCCGAAGTCCCGCTCTTCGA
CATCAAGACCATGCCCGAGCGCGTCTCCGGATCCGTGCGCGATCGCAAGGCCGCCATGCTCATCTGCCTGGTCTTCGCCC
TGCTCGCGCTCGCCCTCTCCGCCATCGGCATCTATGGCGTGCTCGCCTACACGGTCGCCCAACGCACCCGCGAATTCGGC
ATCCGCATGGCGCTCGGCGCCACCGCCGCCGACGTGGTCGGCATGGTCGTCAAGCACGGTGTCCGCCTGGCCGCGCTCGG
CCTGGCCTTCGGCATCGCCACCGCCTTCGCCGTCACCCGCCTGATGACCACTCTCCTCTACGGCGTGCGCCCCACCGACC
CGGCCATCTTCCTCGCCGTCGCCGCCGCCCTGATGACCGTCGCCATCATCGCGTCCGTCATCCCCTCGTTCCGCGTCACC
CGCATCCGCCCCGCCACCGCCCTCCGATCCGAGTAA

Upstream 100 bases:

>100_bases
ATCTCGTCGTCGTCGATCACGCCGAAAAGCTGCCCGTCGAAAACTGACCGCGAACTATTCCCGCTCCCCCGGCGTATTAT
CCTTTGGGAGAGCAGCGCGC

Downstream 100 bases:

>100_bases
GACAGGCCTCCTTGGCCTGTCGACTAATCAGCTTTTCATCCTGTGGGGCAGCCAATCCTGGCTGCCGCCGGCTTTCAGCC
GGCGCACTAATCAGTCTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MFQDLRFGFKLLWKEKAFTVTALLTLALCIGANTAIFSVLHAVILAPLPFPESDRLVAMGNVYPGAGIDKSIQNSIPDYY
DRRGMTDVFESVALYIDAGFDAGAEGSPVRLKADLVTPSFFHVLRASPLMGRLFTEDDAVLDKNQFVILSYGLWKEMFAK
DAAILGRDVRLSGVNYRVVGVMPEAFSFPGREARLWVPLTWTQRQTTDDGRHSNNWNMIARLQPGATVTAVRRRVDALNR
HNVENSGKLRKILEAARFATNITTLKDELIGDVRPTLVLLQCAVAFVLLIGCVNVANLMLVRSSIRMKELAIRYSLGAGR
ARLAMQLLIEAMALAAIGGLCGLLTGAAGIRLLELVGTADLPRGTSIAMDGSVLAFSAAIAVLTGLVFGSVPVYHLVRRD
LNAVFRSTERTGTTEKRTLWTRSALVVCQVSLAFVLLIGSGLLTLSFARLLAVDPGFSAQNVQTAQFSLPRSRYKEDVQL
RNFLGPLLADIRAIPGVTAAGATDSLPFGGDVNASALAVEGYSAAGGELPPVPNWSHIDAGYLPAMQIPLRAGRYFQESD
TADSPKVALIDEFLARKYWPAGKAVGGHIRAGIEAKDTPYTVDGVVGTIKPGDLADQSPRGAVYFDYKQSPARTVHVVVK
TAAANQQAVSAVRASLLKADPEVPLFDIKTMPERVSGSVRDRKAAMLICLVFALLALALSAIGIYGVLAYTVAQRTREFG
IRMALGATAADVVGMVVKHGVRLAALGLAFGIATAFAVTRLMTTLLYGVRPTDPAIFLAVAAALMTVAIIASVIPSFRVT
RIRPATALRSE

Sequences:

>Translated_811_residues
MFQDLRFGFKLLWKEKAFTVTALLTLALCIGANTAIFSVLHAVILAPLPFPESDRLVAMGNVYPGAGIDKSIQNSIPDYY
DRRGMTDVFESVALYIDAGFDAGAEGSPVRLKADLVTPSFFHVLRASPLMGRLFTEDDAVLDKNQFVILSYGLWKEMFAK
DAAILGRDVRLSGVNYRVVGVMPEAFSFPGREARLWVPLTWTQRQTTDDGRHSNNWNMIARLQPGATVTAVRRRVDALNR
HNVENSGKLRKILEAARFATNITTLKDELIGDVRPTLVLLQCAVAFVLLIGCVNVANLMLVRSSIRMKELAIRYSLGAGR
ARLAMQLLIEAMALAAIGGLCGLLTGAAGIRLLELVGTADLPRGTSIAMDGSVLAFSAAIAVLTGLVFGSVPVYHLVRRD
LNAVFRSTERTGTTEKRTLWTRSALVVCQVSLAFVLLIGSGLLTLSFARLLAVDPGFSAQNVQTAQFSLPRSRYKEDVQL
RNFLGPLLADIRAIPGVTAAGATDSLPFGGDVNASALAVEGYSAAGGELPPVPNWSHIDAGYLPAMQIPLRAGRYFQESD
TADSPKVALIDEFLARKYWPAGKAVGGHIRAGIEAKDTPYTVDGVVGTIKPGDLADQSPRGAVYFDYKQSPARTVHVVVK
TAAANQQAVSAVRASLLKADPEVPLFDIKTMPERVSGSVRDRKAAMLICLVFALLALALSAIGIYGVLAYTVAQRTREFG
IRMALGATAADVVGMVVKHGVRLAALGLAFGIATAFAVTRLMTTLLYGVRPTDPAIFLAVAAALMTVAIIASVIPSFRVT
RIRPATALRSE
>Mature_811_residues
MFQDLRFGFKLLWKEKAFTVTALLTLALCIGANTAIFSVLHAVILAPLPFPESDRLVAMGNVYPGAGIDKSIQNSIPDYY
DRRGMTDVFESVALYIDAGFDAGAEGSPVRLKADLVTPSFFHVLRASPLMGRLFTEDDAVLDKNQFVILSYGLWKEMFAK
DAAILGRDVRLSGVNYRVVGVMPEAFSFPGREARLWVPLTWTQRQTTDDGRHSNNWNMIARLQPGATVTAVRRRVDALNR
HNVENSGKLRKILEAARFATNITTLKDELIGDVRPTLVLLQCAVAFVLLIGCVNVANLMLVRSSIRMKELAIRYSLGAGR
ARLAMQLLIEAMALAAIGGLCGLLTGAAGIRLLELVGTADLPRGTSIAMDGSVLAFSAAIAVLTGLVFGSVPVYHLVRRD
LNAVFRSTERTGTTEKRTLWTRSALVVCQVSLAFVLLIGSGLLTLSFARLLAVDPGFSAQNVQTAQFSLPRSRYKEDVQL
RNFLGPLLADIRAIPGVTAAGATDSLPFGGDVNASALAVEGYSAAGGELPPVPNWSHIDAGYLPAMQIPLRAGRYFQESD
TADSPKVALIDEFLARKYWPAGKAVGGHIRAGIEAKDTPYTVDGVVGTIKPGDLADQSPRGAVYFDYKQSPARTVHVVVK
TAAANQQAVSAVRASLLKADPEVPLFDIKTMPERVSGSVRDRKAAMLICLVFALLALALSAIGIYGVLAYTVAQRTREFG
IRMALGATAADVVGMVVKHGVRLAALGLAFGIATAFAVTRLMTTLLYGVRPTDPAIFLAVAAALMTVAIIASVIPSFRVT
RIRPATALRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=295, Percent_Identity=24.0677966101695, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 87129; Mature: 87129

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQDLRFGFKLLWKEKAFTVTALLTLALCIGANTAIFSVLHAVILAPLPFPESDRLVAMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEC
NVYPGAGIDKSIQNSIPDYYDRRGMTDVFESVALYIDAGFDAGAEGSPVRLKADLVTPSF
CCCCCCCCCHHHHHCCCHHHHCCCHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCHHH
FHVLRASPLMGRLFTEDDAVLDKNQFVILSYGLWKEMFAKDAAILGRDVRLSGVNYRVVG
HHHHHCCCHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHCCCEEECCCCEEEEE
VMPEAFSFPGREARLWVPLTWTQRQTTDDGRHSNNWNMIARLQPGATVTAVRRRVDALNR
ECCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
HNVENSGKLRKILEAARFATNITTLKDELIGDVRPTLVLLQCAVAFVLLIGCVNVANLML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRSSIRMKELAIRYSLGAGRARLAMQLLIEAMALAAIGGLCGLLTGAAGIRLLELVGTAD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPRGTSIAMDGSVLAFSAAIAVLTGLVFGSVPVYHLVRRDLNAVFRSTERTGTTEKRTLW
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TRSALVVCQVSLAFVLLIGSGLLTLSFARLLAVDPGFSAQNVQTAQFSLPRSRYKEDVQL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHH
RNFLGPLLADIRAIPGVTAAGATDSLPFGGDVNASALAVEGYSAAGGELPPVPNWSHIDA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GYLPAMQIPLRAGRYFQESDTADSPKVALIDEFLARKYWPAGKAVGGHIRAGIEAKDTPY
CCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCCE
TVDGVVGTIKPGDLADQSPRGAVYFDYKQSPARTVHVVVKTAAANQQAVSAVRASLLKAD
EECCEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEHHCCHHHHHHHHHHHHHCC
PEVPLFDIKTMPERVSGSVRDRKAAMLICLVFALLALALSAIGIYGVLAYTVAQRTREFG
CCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IRMALGATAADVVGMVVKHGVRLAALGLAFGIATAFAVTRLMTTLLYGVRPTDPAIFLAV
EEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAALMTVAIIASVIPSFRVTRIRPATALRSE
HHHHHHHHHHHHHHCCCEEEEECCCHHCCCC
>Mature Secondary Structure
MFQDLRFGFKLLWKEKAFTVTALLTLALCIGANTAIFSVLHAVILAPLPFPESDRLVAMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEC
NVYPGAGIDKSIQNSIPDYYDRRGMTDVFESVALYIDAGFDAGAEGSPVRLKADLVTPSF
CCCCCCCCCHHHHHCCCHHHHCCCHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCHHH
FHVLRASPLMGRLFTEDDAVLDKNQFVILSYGLWKEMFAKDAAILGRDVRLSGVNYRVVG
HHHHHCCCHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHCCCEEECCCCEEEEE
VMPEAFSFPGREARLWVPLTWTQRQTTDDGRHSNNWNMIARLQPGATVTAVRRRVDALNR
ECCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
HNVENSGKLRKILEAARFATNITTLKDELIGDVRPTLVLLQCAVAFVLLIGCVNVANLML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRSSIRMKELAIRYSLGAGRARLAMQLLIEAMALAAIGGLCGLLTGAAGIRLLELVGTAD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPRGTSIAMDGSVLAFSAAIAVLTGLVFGSVPVYHLVRRDLNAVFRSTERTGTTEKRTLW
CCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TRSALVVCQVSLAFVLLIGSGLLTLSFARLLAVDPGFSAQNVQTAQFSLPRSRYKEDVQL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHH
RNFLGPLLADIRAIPGVTAAGATDSLPFGGDVNASALAVEGYSAAGGELPPVPNWSHIDA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
GYLPAMQIPLRAGRYFQESDTADSPKVALIDEFLARKYWPAGKAVGGHIRAGIEAKDTPY
CCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCCE
TVDGVVGTIKPGDLADQSPRGAVYFDYKQSPARTVHVVVKTAAANQQAVSAVRASLLKAD
EECCEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEEHHCCHHHHHHHHHHHHHCC
PEVPLFDIKTMPERVSGSVRDRKAAMLICLVFALLALALSAIGIYGVLAYTVAQRTREFG
CCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IRMALGATAADVVGMVVKHGVRLAALGLAFGIATAFAVTRLMTTLLYGVRPTDPAIFLAV
EEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAALMTVAIIASVIPSFRVTRIRPATALRSE
HHHHHHHHHHHHHHCCCEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA