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The map label for this gene is erpA [H]

Identifier: 116623293

GI number: 116623293

Start: 5323755

End: 5324078

Strand: Direct

Name: erpA [H]

Synonym: Acid_4200

Alternate gene names: 116623293

Gene position: 5323755-5324078 (Clockwise)

Preceding gene: 116623285

Following gene: 116623294

Centisome position: 53.42

GC content: 55.86

Gene sequence:

>324_bases
ATGGTTCAAATTACCGATAGAGCGGTTGGCAAGGTTCGCGAGATCATGGCGTCCCAGGAGCCGGCTCCGGCTGGACTTCG
CATAGCGGTGGTCGGCGGCGGTTGTTCCGGGTTCAGCTACTCGATGGCCTTTGAAAACCAGCCCAACGTTCTCGACAAGA
CTTACAACTACGAGGGTCTGAAAATCTTCGTCGATCAGGCCAGCCTTCTGTACCTCGATGGCGCCGAAGTGGATTACGTC
GAAACGCTCGAAGGCTCCGGCTTCAAGTTCAACAACCCGCAAGTGAAATCCACCTGCGGCTGCGGAAGTTCCTTCCAGGT
CTAA

Upstream 100 bases:

>100_bases
TCTCAACCTGAGCCATCTAAATGGTTGAATGTGGAGCTCGCCGCCCAGATCTGTATAATGGGTTGAGGCAACGCCCGAAA
TTTTCAGGAGTAAATAAACA

Downstream 100 bases:

>100_bases
AACCTCGAAACTCCGTCCACGCTAACGCCCCTCCGCACCCGCGGCGGGGCGTTTTCGTTTGCGTGGCCCATTTTTCAATC
CACTCGCGCTTATCCGGTCA

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MVQITDRAVGKVREIMASQEPAPAGLRIAVVGGGCSGFSYSMAFENQPNVLDKTYNYEGLKIFVDQASLLYLDGAEVDYV
ETLEGSGFKFNNPQVKSTCGCGSSFQV

Sequences:

>Translated_107_residues
MVQITDRAVGKVREIMASQEPAPAGLRIAVVGGGCSGFSYSMAFENQPNVLDKTYNYEGLKIFVDQASLLYLDGAEVDYV
ETLEGSGFKFNNPQVKSTCGCGSSFQV
>Mature_107_residues
MVQITDRAVGKVREIMASQEPAPAGLRIAVVGGGCSGFSYSMAFENQPNVLDKTYNYEGLKIFVDQASLLYLDGAEVDYV
ETLEGSGFKFNNPQVKSTCGCGSSFQV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=34.9056603773585, Blast_Score=83, Evalue=6e-17,
Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=38.3177570093458, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=47.1698113207547, Blast_Score=102, Evalue=5e-24,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=39.622641509434, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=36.7924528301887, Blast_Score=81, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=35.8490566037736, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=35.8490566037736, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71998452, Length=107, Percent_Identity=39.2523364485981, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=32.7102803738318, Blast_Score=84, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325324, Length=128, Percent_Identity=29.6875, Blast_Score=63, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=37.7358490566038, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649697, Length=107, Percent_Identity=37.3831775700935, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11513; Mature: 11513

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQITDRAVGKVREIMASQEPAPAGLRIAVVGGGCSGFSYSMAFENQPNVLDKTYNYEGL
CEEECCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCE
KIFVDQASLLYLDGAEVDYVETLEGSGFKFNNPQVKSTCGCGSSFQV
EEEEECCEEEEECCCCCCEEEECCCCCEEECCCCCCEECCCCCCCCC
>Mature Secondary Structure
MVQITDRAVGKVREIMASQEPAPAGLRIAVVGGGCSGFSYSMAFENQPNVLDKTYNYEGL
CEEECCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCE
KIFVDQASLLYLDGAEVDYVETLEGSGFKFNNPQVKSTCGCGSSFQV
EEEEECCEEEEECCCCCCEEEECCCCCEEECCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA