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The map label for this gene is prpB [C]

Identifier: 116623249

GI number: 116623249

Start: 5273281

End: 5274105

Strand: Direct

Name: prpB [C]

Synonym: Acid_4156

Alternate gene names: 116623249

Gene position: 5273281-5274105 (Clockwise)

Preceding gene: 116623247

Following gene: 116623257

Centisome position: 52.91

GC content: 65.21

Gene sequence:

>825_bases
ATGAGCGCAACGCAAAGTGAAAGAGCAGTCCGCTTCCGGGCCCTTCATGATGGTCCCGGCGTCTTCATCATTCCGAACCC
GTGGGACGTGGGGTCCGCGCGCATCCTGGCCGGTCTTGGCTTCCAGGCGCTGGCCACCTCCAGCGCCGCCTCCGCTGCCG
CGCTGGGCCGGGCGGATGGAGCCCTCACCCGAGACCAGGCGCTGGCACACGCGCGCCTGATCGTCGATAGCACGGATCTG
CCGGTTTCCGCGGACCTGGAGCAGGGTTTTGGTGACGCGCCCGAAGTAGTGGCGGAGACCATCCGGCTCGCGGCCGCCGC
CGGTCTGGTTGGCTGCACCATCGAAGATGCCACCGGCAACCCGAATGCACCGCTCTACGACTTCGAATTGGCCGTGGAGC
GCATTGCCGCCGCCGCTCAGGTTGCGCGCGCACTCCCATTTCCCTTTCTCCTGACTGCAAGGACCCACAACCTGCTGTTC
GCGGAGCCGAGCGTGGACGAGACCATCAGACGGCTGCATTCCTTCGAAAACGCGGGAGCCGATGTGCTCTTTGCCCCCGG
CCTGCCCGATCTTGCGGCGGTGCGCAGAGTGTGCGAAGCGCTGTCGAGGCCCTTCAATTTCATGGTGGGTATCAAAGGAA
AGTCATTTTCCGTGCCCAAACTCGCGGCCGCCGGTGTCCGGCGCATCAGTCTCGCGACCTCGCTCTATCGCGCCGCCATG
ACCGGGTTTCTGGACGCGGTTCACGAAGTGCGGGATGCGGGCCGGTTCGACTTTCTGGATCGCTCCGTGACGACGCCGGA
ACTGCTCAAGCTCATGGGCCTGTGA

Upstream 100 bases:

>100_bases
CCGTACGCGCCCACAAAGAGGGCGAGCGCCAGCGCGGCGATCTTGATTATCCGACTCACGAGGGAAAAGTATATCAGAGA
TGCCCGCGAGGTAACTCCGC

Downstream 100 bases:

>100_bases
ATCGGTTATTGGCCCTTGCAGCCGGTGCGTTCCACCGTGTAAGAGAGGGTCGCAATTTTCCAGCCGTCGGCCGTCTTGAA
AAGCGTGGCAGTGTCTACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSATQSERAVRFRALHDGPGVFIIPNPWDVGSARILAGLGFQALATSSAASAAALGRADGALTRDQALAHARLIVDSTDL
PVSADLEQGFGDAPEVVAETIRLAAAAGLVGCTIEDATGNPNAPLYDFELAVERIAAAAQVARALPFPFLLTARTHNLLF
AEPSVDETIRRLHSFENAGADVLFAPGLPDLAAVRRVCEALSRPFNFMVGIKGKSFSVPKLAAAGVRRISLATSLYRAAM
TGFLDAVHEVRDAGRFDFLDRSVTTPELLKLMGL

Sequences:

>Translated_274_residues
MSATQSERAVRFRALHDGPGVFIIPNPWDVGSARILAGLGFQALATSSAASAAALGRADGALTRDQALAHARLIVDSTDL
PVSADLEQGFGDAPEVVAETIRLAAAAGLVGCTIEDATGNPNAPLYDFELAVERIAAAAQVARALPFPFLLTARTHNLLF
AEPSVDETIRRLHSFENAGADVLFAPGLPDLAAVRRVCEALSRPFNFMVGIKGKSFSVPKLAAAGVRRISLATSLYRAAM
TGFLDAVHEVRDAGRFDFLDRSVTTPELLKLMGL
>Mature_273_residues
SATQSERAVRFRALHDGPGVFIIPNPWDVGSARILAGLGFQALATSSAASAAALGRADGALTRDQALAHARLIVDSTDLP
VSADLEQGFGDAPEVVAETIRLAAAAGLVGCTIEDATGNPNAPLYDFELAVERIAAAAQVARALPFPFLLTARTHNLLFA
EPSVDETIRRLHSFENAGADVLFAPGLPDLAAVRRVCEALSRPFNFMVGIKGKSFSVPKLAAAGVRRISLATSLYRAAMT
GFLDAVHEVRDAGRFDFLDRSVTTPELLKLMGL

Specific function: Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=174, Percent_Identity=35.0574712643678, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 28949; Mature: 28818

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATQSERAVRFRALHDGPGVFIIPNPWDVGSARILAGLGFQALATSSAASAAALGRADG
CCCCCCHHHEEEEEEECCCCEEEECCCCCCCCHHHHHHCCHHHHHHCHHHHHHHHHCCCC
ALTRDQALAHARLIVDSTDLPVSADLEQGFGDAPEVVAETIRLAAAAGLVGCTIEDATGN
CCHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCC
PNAPLYDFELAVERIAAAAQVARALPFPFLLTARTHNLLFAEPSVDETIRRLHSFENAGA
CCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHCCCC
DVLFAPGLPDLAAVRRVCEALSRPFNFMVGIKGKSFSVPKLAAAGVRRISLATSLYRAAM
CEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TGFLDAVHEVRDAGRFDFLDRSVTTPELLKLMGL
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SATQSERAVRFRALHDGPGVFIIPNPWDVGSARILAGLGFQALATSSAASAAALGRADG
CCCCCHHHEEEEEEECCCCEEEECCCCCCCCHHHHHHCCHHHHHHCHHHHHHHHHCCCC
ALTRDQALAHARLIVDSTDLPVSADLEQGFGDAPEVVAETIRLAAAAGLVGCTIEDATGN
CCHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCC
PNAPLYDFELAVERIAAAAQVARALPFPFLLTARTHNLLFAEPSVDETIRRLHSFENAGA
CCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHCCCC
DVLFAPGLPDLAAVRRVCEALSRPFNFMVGIKGKSFSVPKLAAAGVRRISLATSLYRAAM
CEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TGFLDAVHEVRDAGRFDFLDRSVTTPELLKLMGL
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA