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The map label for this gene is macB [H]

Identifier: 116623194

GI number: 116623194

Start: 5210344

End: 5211588

Strand: Reverse

Name: macB [H]

Synonym: Acid_4101

Alternate gene names: 116623194

Gene position: 5211588-5210344 (Counterclockwise)

Preceding gene: 116623195

Following gene: 116623192

Centisome position: 52.3

GC content: 62.97

Gene sequence:

>1245_bases
ATGATCATCTTCTCAGACCTTGGTCAGGCCGTCGCCAACCTGCGCGCCCAGAAAACCCGCACTCTGCTCACCGCCCTCGG
TATCGTCTTTGGCGTCGGCAGCGTAATAGGCATGCTCGCCATCGGCAGTGGAGCCCGCGAGGAATCCCTCCGCTTCATTG
AGCAGCTCGGCGTGCGCAACGTCCTCATCGAGTCCCGCCCCGCCACCAGCCAGGAGGAATTCCAACAGCGCCGCCGCTCC
TCTCCCGGACTCTCCGCTCGCGACGTCCGCATTCTGCGAGCCAACGTCGAGGCCCTGGAGACGCTCTCCGCCCGCCGCTC
CATGCACCCTGCGCGCGTCCTCCCCAAGCCCTCGCGCGATATTCCCGAACTCTATGGCGTCGAGCCGTCCTACAGCGTCA
TTCACAGCCTTCACCTCGCCGAAGGCAAGTTCTTCGATGAGGCCGACGACGCCGCCAGTGCCACCGTCTGCGTTCTCGGC
GAAGGCGCCAAAGTCAATCTCATCGGCTATGGCTCCGCCCTCGGAAAGTTCGTCAAGGTGAACGATTCCTGGATGGAGGT
GGTCGGCGTCCTTCAGGAGCAGGTCATGGCCGGTGCCCAGAACAGCGGCGCCTCCATGCTCGATGTCAACAACATCATCT
ACATCCCTCTGAACGCCATGCAGTACCGCTTCTGGGACCAGGGGAGCAACATGAAGGACGAGCTCGATGGCATCGACATC
CGCCTGCGCGCCGATGCCGATAGCATCGAAGTCGCCAAAGTCGTTACCGCCGTCCTCAACTCCACCCACCACAATATGCA
GGATTTCGGCGTCACCATCCCCGCCGCCCTCCTCGCCCAGCAGCAGCGCACCCAGACCATCTTCACTTACGTGATGGTCG
CGATTGCCGCCATCTCCCTGCTCGTCGGCGGCATCGGCATCATGAACATCGTGCTCGCGACCGTGATGGAACGCACCCGC
GAAATCGGTATCCGCCGCTCCATCGGAGCCCGCCGCTTCGATATCGTCCGCCAGTTCCTCACCGAATCAGTACTCATCTC
CGTCGGTGGCGGACTCTTGGGCATCGCCTTCGGCTTTTTCCTCGCCTGGCTGATCGCCCGCACTGCCGAGTGGAAGACCA
TCGTGACCTCGTCTTCCGTCATCATCGCGTTCGGCGTCTCCGTGGCCGTCGGCGTCATCTTCGGCATCTACCCCGCCGTC
AAAGCCAGCCGCATCAACCCCATCGACGCCCTCCGCTACGAGTAG

Upstream 100 bases:

>100_bases
CCGGCGTCAAGGAAGGCGAGATCGTCGCCATGTCGAACCCCGACCAGCAGCTCAAAACCGCCAGTCCCGAACAGAACGGC
GCCATGAAGGCGCTCGCAAA

Downstream 100 bases:

>100_bases
GATGGGCGTCGTTGCCCGTCCCGCTTGTTTGCTCGCAGGCCGCAAACATCCGCACCGGAATATTCGCCGCCCCATCCGTG
CCGCGACCGTGAGGGAGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIIFSDLGQAVANLRAQKTRTLLTALGIVFGVGSVIGMLAIGSGAREESLRFIEQLGVRNVLIESRPATSQEEFQQRRRS
SPGLSARDVRILRANVEALETLSARRSMHPARVLPKPSRDIPELYGVEPSYSVIHSLHLAEGKFFDEADDAASATVCVLG
EGAKVNLIGYGSALGKFVKVNDSWMEVVGVLQEQVMAGAQNSGASMLDVNNIIYIPLNAMQYRFWDQGSNMKDELDGIDI
RLRADADSIEVAKVVTAVLNSTHHNMQDFGVTIPAALLAQQQRTQTIFTYVMVAIAAISLLVGGIGIMNIVLATVMERTR
EIGIRRSIGARRFDIVRQFLTESVLISVGGGLLGIAFGFFLAWLIARTAEWKTIVTSSSVIIAFGVSVAVGVIFGIYPAV
KASRINPIDALRYE

Sequences:

>Translated_414_residues
MIIFSDLGQAVANLRAQKTRTLLTALGIVFGVGSVIGMLAIGSGAREESLRFIEQLGVRNVLIESRPATSQEEFQQRRRS
SPGLSARDVRILRANVEALETLSARRSMHPARVLPKPSRDIPELYGVEPSYSVIHSLHLAEGKFFDEADDAASATVCVLG
EGAKVNLIGYGSALGKFVKVNDSWMEVVGVLQEQVMAGAQNSGASMLDVNNIIYIPLNAMQYRFWDQGSNMKDELDGIDI
RLRADADSIEVAKVVTAVLNSTHHNMQDFGVTIPAALLAQQQRTQTIFTYVMVAIAAISLLVGGIGIMNIVLATVMERTR
EIGIRRSIGARRFDIVRQFLTESVLISVGGGLLGIAFGFFLAWLIARTAEWKTIVTSSSVIIAFGVSVAVGVIFGIYPAV
KASRINPIDALRYE
>Mature_414_residues
MIIFSDLGQAVANLRAQKTRTLLTALGIVFGVGSVIGMLAIGSGAREESLRFIEQLGVRNVLIESRPATSQEEFQQRRRS
SPGLSARDVRILRANVEALETLSARRSMHPARVLPKPSRDIPELYGVEPSYSVIHSLHLAEGKFFDEADDAASATVCVLG
EGAKVNLIGYGSALGKFVKVNDSWMEVVGVLQEQVMAGAQNSGASMLDVNNIIYIPLNAMQYRFWDQGSNMKDELDGIDI
RLRADADSIEVAKVVTAVLNSTHHNMQDFGVTIPAALLAQQQRTQTIFTYVMVAIAAISLLVGGIGIMNIVLATVMERTR
EIGIRRSIGARRFDIVRQFLTESVLISVGGGLLGIAFGFFLAWLIARTAEWKTIVTSSSVIIAFGVSVAVGVIFGIYPAV
KASRINPIDALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=415, Percent_Identity=28.433734939759, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44938; Mature: 44938

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFSDLGQAVANLRAQKTRTLLTALGIVFGVGSVIGMLAIGSGAREESLRFIEQLGVRN
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHH
VLIESRPATSQEEFQQRRRSSPGLSARDVRILRANVEALETLSARRSMHPARVLPKPSRD
EEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
IPELYGVEPSYSVIHSLHLAEGKFFDEADDAASATVCVLGEGAKVNLIGYGSALGKFVKV
CHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCHHHCCEEEE
NDSWMEVVGVLQEQVMAGAQNSGASMLDVNNIIYIPLNAMQYRFWDQGSNMKDELDGIDI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEECCHHEEEEECCCCCCHHHCCCCEE
RLRADADSIEVAKVVTAVLNSTHHNMQDFGVTIPAALLAQQQRTQTIFTYVMVAIAAISL
EEECCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGGIGIMNIVLATVMERTREIGIRRSIGARRFDIVRQFLTESVLISVGGGLLGIAFGFF
HHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAWLIARTAEWKTIVTSSSVIIAFGVSVAVGVIFGIYPAVKASRINPIDALRYE
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
>Mature Secondary Structure
MIIFSDLGQAVANLRAQKTRTLLTALGIVFGVGSVIGMLAIGSGAREESLRFIEQLGVRN
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHH
VLIESRPATSQEEFQQRRRSSPGLSARDVRILRANVEALETLSARRSMHPARVLPKPSRD
EEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
IPELYGVEPSYSVIHSLHLAEGKFFDEADDAASATVCVLGEGAKVNLIGYGSALGKFVKV
CHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEECCHHHCCEEEE
NDSWMEVVGVLQEQVMAGAQNSGASMLDVNNIIYIPLNAMQYRFWDQGSNMKDELDGIDI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEECCHHEEEEECCCCCCHHHCCCCEE
RLRADADSIEVAKVVTAVLNSTHHNMQDFGVTIPAALLAQQQRTQTIFTYVMVAIAAISL
EEECCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGGIGIMNIVLATVMERTREIGIRRSIGARRFDIVRQFLTESVLISVGGGLLGIAFGFF
HHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LAWLIARTAEWKTIVTSSSVIIAFGVSVAVGVIFGIYPAVKASRINPIDALRYE
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA