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The map label for this gene is sigM [H]

Identifier: 116623185

GI number: 116623185

Start: 5202953

End: 5203483

Strand: Direct

Name: sigM [H]

Synonym: Acid_4092

Alternate gene names: 116623185

Gene position: 5202953-5203483 (Clockwise)

Preceding gene: 116623183

Following gene: 116623186

Centisome position: 52.21

GC content: 59.13

Gene sequence:

>531_bases
ATGCGGGAAGTTCGAGAGGGCGAGGTAGGAAAGCTCGAGACGCTTTTCGATCGCCATTATCAGGGACTTTTCCGTTATTT
TCTCTATTTGACGGGGAACCGCGCGGCTAGCGAGGACCTGGCGCAGGAGGTCTTCTTCCGGATTCTGAAGTACCGGCACA
CGTATCAGCCGGAGGCGGGATTCCGGGCGTGGCTCTATCAGATTGGGCGCAATGTTTACGCCGATTATTTAGGCAAACAG
AAACCGGAAGTGGAGCTGGCGGAGGACGCGGGTGAGATCCGCGGGTCGGAAGCGCCGGCGGACCGGCAGGTTCAGAAGAA
GCAGGAAGCGCTGCTGCTGCGGCGGGCGCTGGCCTCGCTACCCGGCGAGAAGAGGGAAGTGCTGATCATGAGCCGGTTCC
TGGATTTGAGATACGAGGAAATCGCCTCCGTCCTGAAATGCGAAGTGGGGACGGTAAAGGTACGGGTGTACCGGGCAATG
CGGGAGTTGAGCGACCGCTTCTTCGCGCTAAGTGGAGAACGAGCGTCATGA

Upstream 100 bases:

>100_bases
GGCACAGGTGAGAAATCCCGATAACCTTTCCGGTAACCTTTTGCGAGGCGGAGAGTATTTCATAACGTAAGCGGGGAGGC
AAGTGGAGGACGAACTGATC

Downstream 100 bases:

>100_bases
GTTGCGAACGGATTCGGGAGCAGATTCCGGAGGTATTGGCGGGGCGGCTGGACAAGGGCGCGCGGGAAAAACTGGTGGAG
CACCTGGAGAGCTGCGCCGG

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAGFRAWLYQIGRNVYADYLGKQ
KPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASLPGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAM
RELSDRFFALSGERAS

Sequences:

>Translated_176_residues
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAGFRAWLYQIGRNVYADYLGKQ
KPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASLPGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAM
RELSDRFFALSGERAS
>Mature_176_residues
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAGFRAWLYQIGRNVYADYLGKQ
KPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASLPGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAM
RELSDRFFALSGERAS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=142, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20521; Mature: 20521

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
FRAWLYQIGRNVYADYLGKQKPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
PGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAMRELSDRFFALSGERAS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
FRAWLYQIGRNVYADYLGKQKPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
PGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAMRELSDRFFALSGERAS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]