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The map label for this gene is fieF [H]

Identifier: 116623035

GI number: 116623035

Start: 4983299

End: 4984270

Strand: Direct

Name: fieF [H]

Synonym: Acid_3939

Alternate gene names: 116623035

Gene position: 4983299-4984270 (Clockwise)

Preceding gene: 116623033

Following gene: 116623036

Centisome position: 50.0

GC content: 63.79

Gene sequence:

>972_bases
GTGATTTGTCCGTCTCAGTCTACAGGAACACTAAGTGCAACAGGGAATCAGCTCGAACATGGTAGATTCGGACTAGTGAC
TCCGAAGCATCCGGGAGAGGATCGCGAGAAACAATCGGCGGCGTTGGGTTCCCTGCTGGCGGCGGTGGCGCTCACCACAT
TTAAGATCATTGTGGGAGTCGCCACCGGAAGTCTGGGCATCCTGGCCGAAGCGGCGCATTCGGGGCTCGACCTGGTGGCG
GCGGCGCTGACGTTTGTCGCGGTGCGCATCTCCGGGCGTCCGGCCGACAGCGGGCACCTTTACGGTCACGGCAAGGTGGA
GAATCTATCGGCGCTCGCGGAGACACTGCTCCTGCTGGGCACGTGCGCGTGGATCATCCGGGAGGCGGTGCACCGGCTGA
CTACGCACCGGGTAGAGATCGAGGTGACGTTCTGGAGTTTCGCCGTGATGGCGACTTCGATCGCGATCGATGTCTCGCGG
TCGCGGGTACTGGCGCGGACCGCGAAGAAGTACAACAGCCAGGCGCTGGAGGCCGACGCGCTGCACTTCGAGACGGACGT
GTGGAGCTCGGCCGTTGTCGTTCTTGGCCTGGCGTGCGTGACATTGGGCGACCGCATTCCCTCCTTGGTGTGGCTGCGGC
AGGCAGACGCAGTGGCGGCGCTGGGTGTCTCGGCCCTGGTGATTTGGGTGAGCTGGCGGCTGGGAAGGCGCACCGTCGAT
GCGCTGCTGGACTCCGCGCCGGCGGGGATGGAGGAGCGCATACTGGACGCGGTCTCGAGCGTACCCGGAGTGCGGAACTG
CCACAATATCCGGGTGCGATACTCCGGACCGGTGCTCTTCATCGATCTGCACGTGCTGGTGGATGGACGCCAATCGTTGT
TCGAGGCGCATGCGTTGACGGAGACGATCGAGGGCGTGATTCAGGAGATCGTGCCGCAGGCTGACATCACGGTGCATCCC
GAACCGTACTGA

Upstream 100 bases:

>100_bases
GCGACGTGTCGGCGGCCTTATAAACCTCGCCCATACCGCCCGCCCCGATGGGCGCGAGAATTTCATATGGACCAAGGCGG
GTCCCCGGAGTCAGGGGCAT

Downstream 100 bases:

>100_bases
CTGAAGTTAACTGCAGACGGATTGCGCTGCCGCGGACCGGTGGTGTGTACTTCTAAGGTGGCTCACAAACTTCTTCTTAC
AGGAATTTTCGCGGCGTGCG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MICPSQSTGTLSATGNQLEHGRFGLVTPKHPGEDREKQSAALGSLLAAVALTTFKIIVGVATGSLGILAEAAHSGLDLVA
AALTFVAVRISGRPADSGHLYGHGKVENLSALAETLLLLGTCAWIIREAVHRLTTHRVEIEVTFWSFAVMATSIAIDVSR
SRVLARTAKKYNSQALEADALHFETDVWSSAVVVLGLACVTLGDRIPSLVWLRQADAVAALGVSALVIWVSWRLGRRTVD
ALLDSAPAGMEERILDAVSSVPGVRNCHNIRVRYSGPVLFIDLHVLVDGRQSLFEAHALTETIEGVIQEIVPQADITVHP
EPY

Sequences:

>Translated_323_residues
MICPSQSTGTLSATGNQLEHGRFGLVTPKHPGEDREKQSAALGSLLAAVALTTFKIIVGVATGSLGILAEAAHSGLDLVA
AALTFVAVRISGRPADSGHLYGHGKVENLSALAETLLLLGTCAWIIREAVHRLTTHRVEIEVTFWSFAVMATSIAIDVSR
SRVLARTAKKYNSQALEADALHFETDVWSSAVVVLGLACVTLGDRIPSLVWLRQADAVAALGVSALVIWVSWRLGRRTVD
ALLDSAPAGMEERILDAVSSVPGVRNCHNIRVRYSGPVLFIDLHVLVDGRQSLFEAHALTETIEGVIQEIVPQADITVHP
EPY
>Mature_323_residues
MICPSQSTGTLSATGNQLEHGRFGLVTPKHPGEDREKQSAALGSLLAAVALTTFKIIVGVATGSLGILAEAAHSGLDLVA
AALTFVAVRISGRPADSGHLYGHGKVENLSALAETLLLLGTCAWIIREAVHRLTTHRVEIEVTFWSFAVMATSIAIDVSR
SRVLARTAKKYNSQALEADALHFETDVWSSAVVVLGLACVTLGDRIPSLVWLRQADAVAALGVSALVIWVSWRLGRRTVD
ALLDSAPAGMEERILDAVSSVPGVRNCHNIRVRYSGPVLFIDLHVLVDGRQSLFEAHALTETIEGVIQEIVPQADITVHP
EPY

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=279, Percent_Identity=32.9749103942652, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34526; Mature: 34526

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICPSQSTGTLSATGNQLEHGRFGLVTPKHPGEDREKQSAALGSLLAAVALTTFKIIVGV
CCCCCCCCCEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGSLGILAEAAHSGLDLVAAALTFVAVRISGRPADSGHLYGHGKVENLSALAETLLLLG
HCCCHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCCEEECCCHHHHHHHHHHHHHHH
TCAWIIREAVHRLTTHRVEIEVTFWSFAVMATSIAIDVSRSRVLARTAKKYNSQALEADA
HHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCHHCCHHH
LHFETDVWSSAVVVLGLACVTLGDRIPSLVWLRQADAVAALGVSALVIWVSWRLGRRTVD
HEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLDSAPAGMEERILDAVSSVPGVRNCHNIRVRYSGPVLFIDLHVLVDGRQSLFEAHALT
HHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEEEECCHHHHHHHHHHH
ETIEGVIQEIVPQADITVHPEPY
HHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MICPSQSTGTLSATGNQLEHGRFGLVTPKHPGEDREKQSAALGSLLAAVALTTFKIIVGV
CCCCCCCCCEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGSLGILAEAAHSGLDLVAAALTFVAVRISGRPADSGHLYGHGKVENLSALAETLLLLG
HCCCHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCCEEECCCHHHHHHHHHHHHHHH
TCAWIIREAVHRLTTHRVEIEVTFWSFAVMATSIAIDVSRSRVLARTAKKYNSQALEADA
HHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCHHCCHHH
LHFETDVWSSAVVVLGLACVTLGDRIPSLVWLRQADAVAALGVSALVIWVSWRLGRRTVD
HEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLDSAPAGMEERILDAVSSVPGVRNCHNIRVRYSGPVLFIDLHVLVDGRQSLFEAHALT
HHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEEEECCHHHHHHHHHHH
ETIEGVIQEIVPQADITVHPEPY
HHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA