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The map label for this gene is fba [H]

Identifier: 116623032

GI number: 116623032

Start: 4977940

End: 4978962

Strand: Reverse

Name: fba [H]

Synonym: Acid_3936

Alternate gene names: 116623032

Gene position: 4978962-4977940 (Counterclockwise)

Preceding gene: 116623034

Following gene: 116623028

Centisome position: 49.96

GC content: 61.09

Gene sequence:

>1023_bases
ATGCCATTAGTCTCAATGCGGCAGCTCCTCGACGAGGCAGCCAAGGGCGGTTACGGTGTTGGCGCGTTCAACGTCAACAA
CATGGAACAGATCCAGTCGATCATGGAAGCGGCGCGCGAAACTCAGTCGCCGGTCATCATCCAGGCGAGCCGCGGCGCAC
GCGCGTACTCGCAGGATCGCTTCCTGTATCACCTCATGATCGCGGCCACGGAGATCTACCCCGAAATCCCCACCGTGCTT
CATCTGGACCACGGAAACAGCGTTGCCACCTGCAAGAGCGCCATCGATATGGGCTTCACCAGTGTCATGATGGATGGCTC
GCTCATGGAAGACGGCAAGACCCCGTCGAGCTTCGAGTACAACGTCGCCGTCACGAAGGAAGTCGTCGAACTCGCGCACG
CCAAAGGCGTCACGGTGGAAGGCGAAATCGGCTGTCTCGGCGGCATTGAAGACGGCCACGGCGCCGGCGGCGATGGGCTC
AGCCACTTGACCGACCCCGATCAGGCTGTAGAGTTCGTCAAGCAGACCGGCCTCGATGCGCTCGCCATCGCCATCGGCAC
CAGCCACGGCGCTTACAAGTTCAGCAGCAAGCCCACAGGCGAAACGCTGAAGATGAAAGTGCTCATCGAAATCCACAAGA
AGCTGCCGAACGTCCACCTCGTGATGCACGGCTCCTCCAGCGTCCCCAAGGACCTGCAGGACATCATTAATCAATACGGC
GGCAAATTGAAGCCCACGTGGGGCGTCCCGGTCGAAGAAATCCAGCTCGGCATCAAGAACGGCGTCCGCAAGATCAACGT
CGATACCGATAACCGCCTGGCCATCACCGGCGCCATCCGCAAGGTCTTCATCGAGAAGCCCGAAGAGTTCGATCCGCGCA
GCTACATGAAGCCCGCGCGCGACGCCATGAAGAAGGTCGTCGCCCTCCGCATGACCCAGTTCGGCCAGGCCGGCCACGCC
AAAGACTACACCCCCATCCCGCTCGACGAGATGGCCAAGCGCTACCAGCCCGTCACCGCGTAA

Upstream 100 bases:

>100_bases
TTAAATTAAGCGCGTTGCCCCTTCCGGCGCAATCATGCTAGCTTGAGTTTTAAGAGTTCGGGACACCATCCACGCAATTT
TCAAAGGAGAGCACACTCAT

Downstream 100 bases:

>100_bases
TTGATCAACGGGCAAGCTGACGCGTGTCCTACCTTGGTGGGGCATGCTTCAGCTTGCCCCATCCCCATCTCTCAATTACT
CGGCTTTTCCCGCGGCGGCG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPLVSMRQLLDEAAKGGYGVGAFNVNNMEQIQSIMEAARETQSPVIIQASRGARAYSQDRFLYHLMIAATEIYPEIPTVL
HLDHGNSVATCKSAIDMGFTSVMMDGSLMEDGKTPSSFEYNVAVTKEVVELAHAKGVTVEGEIGCLGGIEDGHGAGGDGL
SHLTDPDQAVEFVKQTGLDALAIAIGTSHGAYKFSSKPTGETLKMKVLIEIHKKLPNVHLVMHGSSSVPKDLQDIINQYG
GKLKPTWGVPVEEIQLGIKNGVRKINVDTDNRLAITGAIRKVFIEKPEEFDPRSYMKPARDAMKKVVALRMTQFGQAGHA
KDYTPIPLDEMAKRYQPVTA

Sequences:

>Translated_340_residues
MPLVSMRQLLDEAAKGGYGVGAFNVNNMEQIQSIMEAARETQSPVIIQASRGARAYSQDRFLYHLMIAATEIYPEIPTVL
HLDHGNSVATCKSAIDMGFTSVMMDGSLMEDGKTPSSFEYNVAVTKEVVELAHAKGVTVEGEIGCLGGIEDGHGAGGDGL
SHLTDPDQAVEFVKQTGLDALAIAIGTSHGAYKFSSKPTGETLKMKVLIEIHKKLPNVHLVMHGSSSVPKDLQDIINQYG
GKLKPTWGVPVEEIQLGIKNGVRKINVDTDNRLAITGAIRKVFIEKPEEFDPRSYMKPARDAMKKVVALRMTQFGQAGHA
KDYTPIPLDEMAKRYQPVTA
>Mature_339_residues
PLVSMRQLLDEAAKGGYGVGAFNVNNMEQIQSIMEAARETQSPVIIQASRGARAYSQDRFLYHLMIAATEIYPEIPTVLH
LDHGNSVATCKSAIDMGFTSVMMDGSLMEDGKTPSSFEYNVAVTKEVVELAHAKGVTVEGEIGCLGGIEDGHGAGGDGLS
HLTDPDQAVEFVKQTGLDALAIAIGTSHGAYKFSSKPTGETLKMKVLIEIHKKLPNVHLVMHGSSSVPKDLQDIINQYGG
KLKPTWGVPVEEIQLGIKNGVRKINVDTDNRLAITGAIRKVFIEKPEEFDPRSYMKPARDAMKKVVALRMTQFGQAGHAK
DYTPIPLDEMAKRYQPVTA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=318, Percent_Identity=35.5345911949685, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87082041, Length=321, Percent_Identity=34.5794392523364, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788072, Length=320, Percent_Identity=30.625, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789293, Length=350, Percent_Identity=22.2857142857143, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36936; Mature: 36805

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMRQLLDEAAKGGYGVGAFNVNNMEQIQSIMEAARETQSPVIIQASRGARAYSQDR
CCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
FLYHLMIAATEIYPEIPTVLHLDHGNSVATCKSAIDMGFTSVMMDGSLMEDGKTPSSFEY
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCEEE
NVAVTKEVVELAHAKGVTVEGEIGCLGGIEDGHGAGGDGLSHLTDPDQAVEFVKQTGLDA
EEHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
LAIAIGTSHGAYKFSSKPTGETLKMKVLIEIHKKLPNVHLVMHGSSSVPKDLQDIINQYG
EEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GKLKPTWGVPVEEIQLGIKNGVRKINVDTDNRLAITGAIRKVFIEKPEEFDPRSYMKPAR
CEECCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
DAMKKVVALRMTQFGQAGHAKDYTPIPLDEMAKRYQPVTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
PLVSMRQLLDEAAKGGYGVGAFNVNNMEQIQSIMEAARETQSPVIIQASRGARAYSQDR
CHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
FLYHLMIAATEIYPEIPTVLHLDHGNSVATCKSAIDMGFTSVMMDGSLMEDGKTPSSFEY
HHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCEEE
NVAVTKEVVELAHAKGVTVEGEIGCLGGIEDGHGAGGDGLSHLTDPDQAVEFVKQTGLDA
EEHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCE
LAIAIGTSHGAYKFSSKPTGETLKMKVLIEIHKKLPNVHLVMHGSSSVPKDLQDIINQYG
EEEEEECCCCCEEECCCCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHC
GKLKPTWGVPVEEIQLGIKNGVRKINVDTDNRLAITGAIRKVFIEKPEEFDPRSYMKPAR
CEECCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHH
DAMKKVVALRMTQFGQAGHAKDYTPIPLDEMAKRYQPVTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA