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The map label for this gene is macB [H]

Identifier: 116623006

GI number: 116623006

Start: 4942941

End: 4944986

Strand: Reverse

Name: macB [H]

Synonym: Acid_3910

Alternate gene names: 116623006

Gene position: 4944986-4942941 (Counterclockwise)

Preceding gene: 116623010

Following gene: 116623002

Centisome position: 49.62

GC content: 63.15

Gene sequence:

>2046_bases
ATGTTCGATTCATTCGGTATTCGCCCTGCGCTGGGCCGAGTATTCACAGAGAACGACGATCTTACACCTGGCGCGCACGC
CTACGCCGTCCTTTCCTATGACTACTGGGAGCGGCGCTTTGCGAAAGATCCAAACGTGGTTGGGCGGATCTTCCGAACGG
GCGATGAGGTGTTTCAAATCGTGGGCGTCGCCGAGGGACCCTTCACGGGTACCGAACCGGGCAAGGTCACGGATGTTTTC
CTTCCCACGATGATGATGAAGAACCACGCGATCGTGCGTTCCGATTACCAGTGGTTTCTCACCTTTGTCCAATTGAATGC
CGGCGTGAGCGCACCCCTGGTACGGGAAAAATTGCGGCCTGTGTTTCGAGCGTTTGTGGAAGAGCGGGCAAAAGTCTCGC
CGGTAACGGCGAGACGGGCTCAAAGACTCGAGATGAATCGTGCAGCAGCCGGCGTTTCCGGATTGCAGCGCGGGTATGGG
ACGGCGCTGCTCGTGCTCGGGGCGCTGGTGAATCTGGTGCTGCTCATCGCCTGCGCCAACGTGGCCAACCTGATGACGGC
CCAGGCAATGGGGCGCCAGCGCGAGATGGCGCTGCGAGTTGCGATCGGCGCCGGCCGAGGCCGCCTGGTGCAACTGGTGG
TGATGGAATGCGCGTGGCCGGCATGCTTCGCCGCAGGTATCGGCGCCTGCTTCGCCGGGTGGGCCGCACCTCTGGTGGTG
GGCATGATCGGCACGCCGGACAACGCGGTTCGCCTGATTCTTTCAGCCGACTGGCGGGTGCTGGGATTCGGCGTAGCCAT
GGCGCTTGGCTGCACGCTCCTTTTTGGTCTGGCGCCGGCGCTACGAGCTTCCGGGGTGAAGCCGGTAAGTGCGCTGAAAG
GCGGCACTCCGCTCAGTCGGGCACGCATGATGCGACTGCTGATCGCCGCCCAGGTGGCTTTCTGTGTCCAGGTGCTCTTG
GGGACCGCGCTCTTCATGGCCACTTCCGGGAGGCTGTCCCGTCAAGAGACCGGGTTCTCCTCCGAGCGGCTTCTCGCTTT
GGAGACAGTGACACCACAGCTACAGCGGGAGTCGATGTGGAACCAGGTTGCCGATCGTCTCAGAACTGTGCCGGGAGTGG
AGGCGGTGGCACTATGCGAGTGGCCGCTGATGACTGGAGGAGTTTGGGACGGCTGGATCTCGGTCAATGGGGCCGCGCCA
GGCCCGACGGCGTCCTACTTCCTCAGCGTCTCGCCGGAATGGCGCGCGCTGATGAAAATTCCCCTGCTCGAAGGCAGGGA
CCTGCGCACCGGCGACACGTTGCCGGGTTCGGCGTTGGTCAACCAGGCATTCGCCCGACAGTATCTGGACGGGGGGCATC
CGGTGGGAAGGTGGTTTGAGATAGTGCAGAACGAGGGGCACCGTCAGCGCTACCAGATTGTGGGACTGGTCGGCGATGCG
CGCTACCGGAATATGCGGGAGCCCATACAGCCCACCGCGTATTTTCCCTTCCAGGGCGCCTACAGGCGGGCCACGCTCCT
CGTCCGCACCGCCAGCGAAGACCCGAAGTCGACGGCCTCCGCACTGCGGCTGGAGGTGCCCCAGGCGCGCCCCGGATTCC
GCGTCAGTAACATCCAGACTCAGAGAGCGCTGATCGAGCAGCATGCCGTGCGTGAGCGGCTGCTCTCGATACTCGCGCTG
TTCTTTGGCGTGGTGGCCCTGTCGCTGGCCGGTGTCGGTTTGTATGGAGTTCTCGACTATTCGGTACTCCAGCGGCGGCG
GGAGATTGGGATCCGCATGGCCATTGGTGCGCAAGCCAGCGACATCGCGCGGCGTGTCGTCACGGATGTGTTGGTAGTGG
TGCTGGCGGGAGAGATATTCGGGCTCGCTTTAGGGATCTCATCGGTACGATTCATCGAGGCGCTGCTTTTTGAGGTCAAG
GCTACGGATATGGGCGCGCTTGCGCTGCCGACGGTAGCCATTCTGGCGGTCGCGCTGCTAGCGGCAGTACCGGCGGTGAT
CCGCGCGATTCGGATCGATCCCGTTCGCATGCTGCGATCGGAATAG

Upstream 100 bases:

>100_bases
GGCCGAGTTGATCGCAGTCTCGAGCGCCGTCCACATCGACCTTACCTAGGGGTCCGATCAGGAAACCGGGAAGGCGTATC
AACAGTACGTCTCGGGATGG

Downstream 100 bases:

>100_bases
TCGAGGCGCCGGGGGCAGGGACCTTAGGTCAAACCGGATGCGCGCGGCGTTTTGCCGGCGTCATCCGCGCTTTGTGGCGA
TGAACAGGCAATCCGGAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MFDSFGIRPALGRVFTENDDLTPGAHAYAVLSYDYWERRFAKDPNVVGRIFRTGDEVFQIVGVAEGPFTGTEPGKVTDVF
LPTMMMKNHAIVRSDYQWFLTFVQLNAGVSAPLVREKLRPVFRAFVEERAKVSPVTARRAQRLEMNRAAAGVSGLQRGYG
TALLVLGALVNLVLLIACANVANLMTAQAMGRQREMALRVAIGAGRGRLVQLVVMECAWPACFAAGIGACFAGWAAPLVV
GMIGTPDNAVRLILSADWRVLGFGVAMALGCTLLFGLAPALRASGVKPVSALKGGTPLSRARMMRLLIAAQVAFCVQVLL
GTALFMATSGRLSRQETGFSSERLLALETVTPQLQRESMWNQVADRLRTVPGVEAVALCEWPLMTGGVWDGWISVNGAAP
GPTASYFLSVSPEWRALMKIPLLEGRDLRTGDTLPGSALVNQAFARQYLDGGHPVGRWFEIVQNEGHRQRYQIVGLVGDA
RYRNMREPIQPTAYFPFQGAYRRATLLVRTASEDPKSTASALRLEVPQARPGFRVSNIQTQRALIEQHAVRERLLSILAL
FFGVVALSLAGVGLYGVLDYSVLQRRREIGIRMAIGAQASDIARRVVTDVLVVVLAGEIFGLALGISSVRFIEALLFEVK
ATDMGALALPTVAILAVALLAAVPAVIRAIRIDPVRMLRSE

Sequences:

>Translated_681_residues
MFDSFGIRPALGRVFTENDDLTPGAHAYAVLSYDYWERRFAKDPNVVGRIFRTGDEVFQIVGVAEGPFTGTEPGKVTDVF
LPTMMMKNHAIVRSDYQWFLTFVQLNAGVSAPLVREKLRPVFRAFVEERAKVSPVTARRAQRLEMNRAAAGVSGLQRGYG
TALLVLGALVNLVLLIACANVANLMTAQAMGRQREMALRVAIGAGRGRLVQLVVMECAWPACFAAGIGACFAGWAAPLVV
GMIGTPDNAVRLILSADWRVLGFGVAMALGCTLLFGLAPALRASGVKPVSALKGGTPLSRARMMRLLIAAQVAFCVQVLL
GTALFMATSGRLSRQETGFSSERLLALETVTPQLQRESMWNQVADRLRTVPGVEAVALCEWPLMTGGVWDGWISVNGAAP
GPTASYFLSVSPEWRALMKIPLLEGRDLRTGDTLPGSALVNQAFARQYLDGGHPVGRWFEIVQNEGHRQRYQIVGLVGDA
RYRNMREPIQPTAYFPFQGAYRRATLLVRTASEDPKSTASALRLEVPQARPGFRVSNIQTQRALIEQHAVRERLLSILAL
FFGVVALSLAGVGLYGVLDYSVLQRRREIGIRMAIGAQASDIARRVVTDVLVVVLAGEIFGLALGISSVRFIEALLFEVK
ATDMGALALPTVAILAVALLAAVPAVIRAIRIDPVRMLRSE
>Mature_681_residues
MFDSFGIRPALGRVFTENDDLTPGAHAYAVLSYDYWERRFAKDPNVVGRIFRTGDEVFQIVGVAEGPFTGTEPGKVTDVF
LPTMMMKNHAIVRSDYQWFLTFVQLNAGVSAPLVREKLRPVFRAFVEERAKVSPVTARRAQRLEMNRAAAGVSGLQRGYG
TALLVLGALVNLVLLIACANVANLMTAQAMGRQREMALRVAIGAGRGRLVQLVVMECAWPACFAAGIGACFAGWAAPLVV
GMIGTPDNAVRLILSADWRVLGFGVAMALGCTLLFGLAPALRASGVKPVSALKGGTPLSRARMMRLLIAAQVAFCVQVLL
GTALFMATSGRLSRQETGFSSERLLALETVTPQLQRESMWNQVADRLRTVPGVEAVALCEWPLMTGGVWDGWISVNGAAP
GPTASYFLSVSPEWRALMKIPLLEGRDLRTGDTLPGSALVNQAFARQYLDGGHPVGRWFEIVQNEGHRQRYQIVGLVGDA
RYRNMREPIQPTAYFPFQGAYRRATLLVRTASEDPKSTASALRLEVPQARPGFRVSNIQTQRALIEQHAVRERLLSILAL
FFGVVALSLAGVGLYGVLDYSVLQRRREIGIRMAIGAQASDIARRVVTDVLVVVLAGEIFGLALGISSVRFIEALLFEVK
ATDMGALALPTVAILAVALLAAVPAVIRAIRIDPVRMLRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 73913; Mature: 73913

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS01073 RIBOSOMAL_L24E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSFGIRPALGRVFTENDDLTPGAHAYAVLSYDYWERRFAKDPNVVGRIFRTGDEVFQI
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGVAEGPFTGTEPGKVTDVFLPTMMMKNHAIVRSDYQWFLTFVQLNAGVSAPLVREKLRP
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCHHHHHHHHH
VFRAFVEERAKVSPVTARRAQRLEMNRAAAGVSGLQRGYGTALLVLGALVNLVLLIACAN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANLMTAQAMGRQREMALRVAIGAGRGRLVQLVVMECAWPACFAAGIGACFAGWAAPLVV
HHHHHHHHHHCHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GMIGTPDNAVRLILSADWRVLGFGVAMALGCTLLFGLAPALRASGVKPVSALKGGTPLSR
HCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHH
ARMMRLLIAAQVAFCVQVLLGTALFMATSGRLSRQETGFSSERLLALETVTPQLQRESMW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEHHCHHHHHHHHH
NQVADRLRTVPGVEAVALCEWPLMTGGVWDGWISVNGAAPGPTASYFLSVSPEWRALMKI
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHCC
PLLEGRDLRTGDTLPGSALVNQAFARQYLDGGHPVGRWFEIVQNEGHRQRYQIVGLVGDA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEEECCH
RYRNMREPIQPTAYFPFQGAYRRATLLVRTASEDPKSTASALRLEVPQARPGFRVSNIQT
HHHHCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHEEECCCCCCCCEECCHHH
QRALIEQHAVRERLLSILALFFGVVALSLAGVGLYGVLDYSVLQRRREIGIRMAIGAQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCHH
DIARRVVTDVLVVVLAGEIFGLALGISSVRFIEALLFEVKATDMGALALPTVAILAVALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAVPAVIRAIRIDPVRMLRSE
HHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MFDSFGIRPALGRVFTENDDLTPGAHAYAVLSYDYWERRFAKDPNVVGRIFRTGDEVFQI
CCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGVAEGPFTGTEPGKVTDVFLPTMMMKNHAIVRSDYQWFLTFVQLNAGVSAPLVREKLRP
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHCCCCCCHHHHHHHHH
VFRAFVEERAKVSPVTARRAQRLEMNRAAAGVSGLQRGYGTALLVLGALVNLVLLIACAN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANLMTAQAMGRQREMALRVAIGAGRGRLVQLVVMECAWPACFAAGIGACFAGWAAPLVV
HHHHHHHHHHCHHHHHEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GMIGTPDNAVRLILSADWRVLGFGVAMALGCTLLFGLAPALRASGVKPVSALKGGTPLSR
HCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHH
ARMMRLLIAAQVAFCVQVLLGTALFMATSGRLSRQETGFSSERLLALETVTPQLQRESMW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEHHCHHHHHHHHH
NQVADRLRTVPGVEAVALCEWPLMTGGVWDGWISVNGAAPGPTASYFLSVSPEWRALMKI
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHCC
PLLEGRDLRTGDTLPGSALVNQAFARQYLDGGHPVGRWFEIVQNEGHRQRYQIVGLVGDA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEEECCH
RYRNMREPIQPTAYFPFQGAYRRATLLVRTASEDPKSTASALRLEVPQARPGFRVSNIQT
HHHHCCCCCCCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHEEECCCCCCCCEECCHHH
QRALIEQHAVRERLLSILALFFGVVALSLAGVGLYGVLDYSVLQRRREIGIRMAIGAQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCCHH
DIARRVVTDVLVVVLAGEIFGLALGISSVRFIEALLFEVKATDMGALALPTVAILAVALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAVPAVIRAIRIDPVRMLRSE
HHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA