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The map label for this gene is sglT [H]

Identifier: 116622941

GI number: 116622941

Start: 4878171

End: 4879850

Strand: Direct

Name: sglT [H]

Synonym: Acid_3843

Alternate gene names: 116622941

Gene position: 4878171-4879850 (Clockwise)

Preceding gene: 116622940

Following gene: 116622942

Centisome position: 48.95

GC content: 61.13

Gene sequence:

>1680_bases
TTGAAACTCGCAGCGGTTGATTACGCAATTCTCGCTCTCTACTTCGCGTTCGTCCTCGGCATAGGCTGGCGCCTTCGCAA
GAAGATCTCCACCTCGGGCGACTTCCTCACCTCAGGCCACTCGGTCCCCGTCTGGATCACCAGCCTTGCCTTCCTTGCGG
CCAACCTTGGCGCACAGGAGCTGGTTGGCATGTCCGGGAACGGGGCCAAGTACGGCATTATGACCGCTCACTTCTACTGG
GTGGGGGCAGTGCCGGCCATGATCTTCGTCGGCATATTCATGATGCCCTTCTACTACGGAAGTCGTGCCCGCTCGGTCCC
CGAGTACCTCAAACTCCGCTTCGACGAAAAGACCCGCGCGCTCAACGCTCTCACCTTCGCCGGGATGACGATCTTCTCCT
CCGGCATTTCGATGTACGCCCTGGGGCTTCTGCTCCGCCTGGTGCTCGGCTGGGACTTCACAACCAGCGTCCTCTGCTCC
GCCGCCATCGTGCTGGCCTATACCTTCCTGGGCGGGCTCACCAGCGCCATCTATAACGAAGTGCTGCAATTCTTCCTGAT
CGTGATGGGCTTCTCTCCCCTCGCCATCATGGCCGTGATGAAGGCCGGAGGGTGGAGCGGGATGTCCGCCCGGCTCGCCC
AAATGACCCTGCCCGGCGGCATCAACGGCAGCGTCATGACGCACAGTTGGAAGTACATGGCCCACACCAGCGAGAACCCG
ATGGGGATCGAAATCTTCGGCCTCGTCGCCGGACTCGGTTTCGTCATGTCCTTCGGTTACTGGTGTACGGATTTCCTGGT
GATCCAGCGAGCCATGGCCGCCAACTCCATGTCGGCTTCGCGCCGCACCCCGGTAATCGCCGCGCTGCCGAAAATGATGA
TGCCCTTCATCGTGATCGTCCCCGGCATCGCAGCCCTGGCTCTCTCCCAAATGGGCGTGGGCTATGATCTCCCGATGAAG
AATGGCGGCCCCGATTACGATCAGGTGCTCACCACCCTGATGGGCAAGTTCTATCCGGCCGGGATGCTCGGGGTCGGGCT
CACCGGACTCATGGCATCCTTCATGAGCGGAATGGCCGGCAATGTCACCGCCTTCAATACCGTCTTCACCTACGATCTCT
ACCAGACCTACATCAAACCCGGCCAGCCCGACCACCACTACCTCACGGTGGGGCGCATCACCACCGTGGTGGGCGTGGCG
CTTTCCATCTGCACCGCCTATCTGGCGCAGCAGTACAACAGCATCAACGATCTGCTCCAGCTGGTCTTCAGCTTCGTCAA
TGCGCCCCTCTTCGGCACCTTTCTGCTCGGCATGTTCTGGAAGCGCACTACCGGACACGGCGCCTTCTTCGGCCTGCTGA
GCGGCACCGCCGCCGCGGCCCTGACGCAAGGCTTGACGGTGGCCGAAGGTAAGGGCGGCTGGATGGCCAACCTCCACGAG
TTCCCCTCCTCCATGGCACAGAACTTCTGGATCGCGATTACCGCCTGGACCGTCTGTTTCGCCATCACTATCGCCGTCAG
TATGGTCACCACCCCGCGTCCGGAAAAGGAGTTGCACGGCCTGGTATATGGCCTCACTGAGCTCAAGCACGACGAGGGAG
TAAGCTGGTATCTGCGTCCCGTGCCCCTGGCGATTGCCATTGGCGCCCTGGCTTTGTTTCTGAATTTCTGGTTCGCCTGA

Upstream 100 bases:

>100_bases
GCCTTCCTGAACTCCCTGTAGCGTAACGGGGACTTCCCTCTGCCTTGTGATAGACTCATGTTTCCATTTTTTGAATCTGT
AACATCCCAGAGGTTCGCTT

Downstream 100 bases:

>100_bases
CATGCTGGATCTACGAGTGCCTACGGGCTTCTTCTTCACCCTGATCGGCCTGATACTGGTCGCGATGGGCGTGTTCTCGC
CGTCCGAACGGGCGGCGCTG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MKLAAVDYAILALYFAFVLGIGWRLRKKISTSGDFLTSGHSVPVWITSLAFLAANLGAQELVGMSGNGAKYGIMTAHFYW
VGAVPAMIFVGIFMMPFYYGSRARSVPEYLKLRFDEKTRALNALTFAGMTIFSSGISMYALGLLLRLVLGWDFTTSVLCS
AAIVLAYTFLGGLTSAIYNEVLQFFLIVMGFSPLAIMAVMKAGGWSGMSARLAQMTLPGGINGSVMTHSWKYMAHTSENP
MGIEIFGLVAGLGFVMSFGYWCTDFLVIQRAMAANSMSASRRTPVIAALPKMMMPFIVIVPGIAALALSQMGVGYDLPMK
NGGPDYDQVLTTLMGKFYPAGMLGVGLTGLMASFMSGMAGNVTAFNTVFTYDLYQTYIKPGQPDHHYLTVGRITTVVGVA
LSICTAYLAQQYNSINDLLQLVFSFVNAPLFGTFLLGMFWKRTTGHGAFFGLLSGTAAAALTQGLTVAEGKGGWMANLHE
FPSSMAQNFWIAITAWTVCFAITIAVSMVTTPRPEKELHGLVYGLTELKHDEGVSWYLRPVPLAIAIGALALFLNFWFA

Sequences:

>Translated_559_residues
MKLAAVDYAILALYFAFVLGIGWRLRKKISTSGDFLTSGHSVPVWITSLAFLAANLGAQELVGMSGNGAKYGIMTAHFYW
VGAVPAMIFVGIFMMPFYYGSRARSVPEYLKLRFDEKTRALNALTFAGMTIFSSGISMYALGLLLRLVLGWDFTTSVLCS
AAIVLAYTFLGGLTSAIYNEVLQFFLIVMGFSPLAIMAVMKAGGWSGMSARLAQMTLPGGINGSVMTHSWKYMAHTSENP
MGIEIFGLVAGLGFVMSFGYWCTDFLVIQRAMAANSMSASRRTPVIAALPKMMMPFIVIVPGIAALALSQMGVGYDLPMK
NGGPDYDQVLTTLMGKFYPAGMLGVGLTGLMASFMSGMAGNVTAFNTVFTYDLYQTYIKPGQPDHHYLTVGRITTVVGVA
LSICTAYLAQQYNSINDLLQLVFSFVNAPLFGTFLLGMFWKRTTGHGAFFGLLSGTAAAALTQGLTVAEGKGGWMANLHE
FPSSMAQNFWIAITAWTVCFAITIAVSMVTTPRPEKELHGLVYGLTELKHDEGVSWYLRPVPLAIAIGALALFLNFWFA
>Mature_559_residues
MKLAAVDYAILALYFAFVLGIGWRLRKKISTSGDFLTSGHSVPVWITSLAFLAANLGAQELVGMSGNGAKYGIMTAHFYW
VGAVPAMIFVGIFMMPFYYGSRARSVPEYLKLRFDEKTRALNALTFAGMTIFSSGISMYALGLLLRLVLGWDFTTSVLCS
AAIVLAYTFLGGLTSAIYNEVLQFFLIVMGFSPLAIMAVMKAGGWSGMSARLAQMTLPGGINGSVMTHSWKYMAHTSENP
MGIEIFGLVAGLGFVMSFGYWCTDFLVIQRAMAANSMSASRRTPVIAALPKMMMPFIVIVPGIAALALSQMGVGYDLPMK
NGGPDYDQVLTTLMGKFYPAGMLGVGLTGLMASFMSGMAGNVTAFNTVFTYDLYQTYIKPGQPDHHYLTVGRITTVVGVA
LSICTAYLAQQYNSINDLLQLVFSFVNAPLFGTFLLGMFWKRTTGHGAFFGLLSGTAAAALTQGLTVAEGKGGWMANLHE
FPSSMAQNFWIAITAWTVCFAITIAVSMVTTPRPEKELHGLVYGLTELKHDEGVSWYLRPVPLAIAIGALALFLNFWFA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=559, Percent_Identity=26.4758497316637, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI4507031, Length=550, Percent_Identity=25.2727272727273, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4507033, Length=554, Percent_Identity=25.9927797833935, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI109659836, Length=482, Percent_Identity=26.7634854771784, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI110835708, Length=557, Percent_Identity=25.4937163375224, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI17941285, Length=459, Percent_Identity=27.0152505446623, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI109659839, Length=498, Percent_Identity=25.9036144578313, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI206597483, Length=537, Percent_Identity=26.2569832402235, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI206597487, Length=469, Percent_Identity=26.226012793177, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI256985183, Length=444, Percent_Identity=26.1261261261261, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI167466278, Length=480, Percent_Identity=23.3333333333333, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI157671931, Length=284, Percent_Identity=25, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4507035, Length=447, Percent_Identity=23.2662192393736, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790113, Length=436, Percent_Identity=22.9357798165138, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787251, Length=451, Percent_Identity=21.2860310421286, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573698, Length=459, Percent_Identity=23.3115468409586, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641117, Length=467, Percent_Identity=25.2676659528908, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24651739, Length=501, Percent_Identity=20.1596806387226, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362918, Length=503, Percent_Identity=22.0675944333996, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24645928, Length=468, Percent_Identity=22.4358974358974, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651741, Length=480, Percent_Identity=21.875, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281362054, Length=462, Percent_Identity=23.1601731601732, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362052, Length=462, Percent_Identity=23.1601731601732, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362050, Length=462, Percent_Identity=23.1601731601732, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648056, Length=462, Percent_Identity=23.1601731601732, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356827, Length=462, Percent_Identity=23.1601731601732, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60514; Mature: 60514

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAAVDYAILALYFAFVLGIGWRLRKKISTSGDFLTSGHSVPVWITSLAFLAANLGAQE
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCHHH
LVGMSGNGAKYGIMTAHFYWVGAVPAMIFVGIFMMPFYYGSRARSVPEYLKLRFDEKTRA
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCHHHHH
LNALTFAGMTIFSSGISMYALGLLLRLVLGWDFTTSVLCSAAIVLAYTFLGGLTSAIYNE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLQFFLIVMGFSPLAIMAVMKAGGWSGMSARLAQMTLPGGINGSVMTHSWKYMAHTSENP
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCCCCCEEECCEEEEEECCCCC
MGIEIFGLVAGLGFVMSFGYWCTDFLVIQRAMAANSMSASRRTPVIAALPKMMMPFIVIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
PGIAALALSQMGVGYDLPMKNGGPDYDQVLTTLMGKFYPAGMLGVGLTGLMASFMSGMAG
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
NVTAFNTVFTYDLYQTYIKPGQPDHHYLTVGRITTVVGVALSICTAYLAQQYNSINDLLQ
CCEEHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LVFSFVNAPLFGTFLLGMFWKRTTGHGAFFGLLSGTAAAALTQGLTVAEGKGGWMANLHE
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
FPSSMAQNFWIAITAWTVCFAITIAVSMVTTPRPEKELHGLVYGLTELKHDEGVSWYLRP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECH
VPLAIAIGALALFLNFWFA
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLAAVDYAILALYFAFVLGIGWRLRKKISTSGDFLTSGHSVPVWITSLAFLAANLGAQE
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCHHH
LVGMSGNGAKYGIMTAHFYWVGAVPAMIFVGIFMMPFYYGSRARSVPEYLKLRFDEKTRA
HCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCHHHHH
LNALTFAGMTIFSSGISMYALGLLLRLVLGWDFTTSVLCSAAIVLAYTFLGGLTSAIYNE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLQFFLIVMGFSPLAIMAVMKAGGWSGMSARLAQMTLPGGINGSVMTHSWKYMAHTSENP
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHEECCCCCCCCEEECCEEEEEECCCCC
MGIEIFGLVAGLGFVMSFGYWCTDFLVIQRAMAANSMSASRRTPVIAALPKMMMPFIVIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
PGIAALALSQMGVGYDLPMKNGGPDYDQVLTTLMGKFYPAGMLGVGLTGLMASFMSGMAG
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
NVTAFNTVFTYDLYQTYIKPGQPDHHYLTVGRITTVVGVALSICTAYLAQQYNSINDLLQ
CCEEHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LVFSFVNAPLFGTFLLGMFWKRTTGHGAFFGLLSGTAAAALTQGLTVAEGKGGWMANLHE
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
FPSSMAQNFWIAITAWTVCFAITIAVSMVTTPRPEKELHGLVYGLTELKHDEGVSWYLRP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECH
VPLAIAIGALALFLNFWFA
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]