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The map label for this gene is macB [H]

Identifier: 116622897

GI number: 116622897

Start: 4821442

End: 4823877

Strand: Direct

Name: macB [H]

Synonym: Acid_3798

Alternate gene names: 116622897

Gene position: 4821442-4823877 (Clockwise)

Preceding gene: 116622892

Following gene: 116622899

Centisome position: 48.38

GC content: 65.76

Gene sequence:

>2436_bases
ATGACGGGGATCCTGGAAGACTTGCGCTACGGCCTGAGGGGCTTAGCGAAAAACCGCGGCTTCGCTGTCGTAGCGGTGTT
GTCACTGGCGCTCGGCATCGGCGCTAATACCACCATCTTCACGCTGCTGAACGCGGTCTTCCTGCGCCCTCTTCCCGTAC
ATGACGCCTCCAGCCTGGTCGCCGTCTTCACCATTGACCTGCGCAATCCCGGACTACTGAACTGCTCGTACCCGAATTAT
CGCGATTATCGCGATCAAAACACCGTCTTCTCCTCCCTGCTCCTGTATACCTCTGTGACCGTCAACCTCACCGGCCGCGG
CGATCCCCAGCTCCTGATGGGACAGCTGGTCTCCGGCAATTTTTTCAATACCCTCGGCGTGAACCCGGTGCTTGGCCGCG
GCTTCCGCCCTGACGAGGACGCCAGCCCAGGCGCGGCCGCCGTCGTGGTCATCAGCCACCCGCTTTGGCAGCGCCTGTTC
GCCGGACGCCCCGACGTGGTCGGCCGGCCTATCGAGCTCGGCGGGCGGACCTACTCCATCGTCGGTGTCGCGCCTCCCGG
CTTCGTCGGCTTGAACCAGTTGATCGGGGCAGATGTCTTTGTACCTCTTTCCATGTATCCGCAGTTGTACCCGGCTCCCG
CGCAGGTCAACCAGCGGAGCGCCCTCATGTTCTCCGCAGTCGGCCGCCTCAAACCCGGAATTGGAATCGCGCAGGCCGGT
GCCGCGATGCGCGGCCTCGCGCAGCAACTGGAGCGCGAACACCCGGAGAATCGCGGCCGCAGTCTGGCCCTGACCTCGAT
CAGCGAAGCCGCTCTCAGCGCGCGCACCCGCCCCGTCATCTCGCGCGCCGGAGCCGTCCTGATGACGGTCTCCGCGCTTA
TTCTCCTGATCGCCTGCGGCAACGTCGCCAACCTTCTGCTGGCGCGTGCCGCCGGACGCAATAAGGAAATCGCGATCCGC
CTGGCGATGGGCGCCACCCGTCCCAGACTGGTCCGGCAGCTCCTCACCGAAAGCCTGCTCCTGGCATTCGTGGGTGGCGC
GCTCGGACTCTTCCTGGCGCGTTGGGCCCGCGACCTGCTTTGGGGAATCCGTCCCGCGACCTTCAATCACGCCGGCTTCC
ACCTGGACCTGGATCCCCGCGTCTTGCTCTTCACGCTGGGAATCTCCGTGCTGACCGGTGTGCTCTTCGGCCTGGCACCC
GCCCTGCGCGCCACCAAGGCGAACCTGGCGACCGACCTCAAGGAGCGCGCCGGTGTGCAAAGCAGCTTCCGCTACACCTG
GGGCCTTCGCGCAACCCTCGTGATGGCGCAGGTGGCGCTCTCCCTAATCGCGCTGATCGGCGCCGGACTCTTCGTGCGCA
GCCTGCAAAACGCCGGGCAGGTCGATCCCGGCTTCGATGCTGTCCATCTCGGAATCGTGGCCTACAATGTCACCGACCAG
GGCTACAACGAAGGCCGCGGCCGCGATTTCCACGAGCGCGCCGTGGCGCGCGCCGCCGCCGTACCCGGAGTGATCTCGGC
CAGCCTCGCCATGGACGTTCCTTTTCACGTGGCCTTTTCGCGCAAGGTGGTGCTCGAAGGGCAGGAGAATACCGCGCAGG
GACGTCCCACCTTGACCAGCGTCGTCTCGCCCGGCTACCTGCATACCGTGGCCATTCCGCTGCTTCGCGGCCGCGACTTC
AGCCCGCTCGATACCAAGACCACGCCCCGCGTCGCCATCGTCAACGAGGCCGCCGCTGCCGCCTTTTGGCCGGGACGCAA
CCCCATCGGCCAGCGCATTTCCTTCACCACCGACCGCTCGCCTTTCGAAGTCATCGGCGTGGCGCGCAACGCCAACTACC
AGGCCATCGACGAAGCGCCGCAGGCGCTGGTCTATCTCTCGCTCGTGCAATTCTACTTCCCCACCGCGGTCCTCTATGTA
CACACCGCCGGTGACCCCACCACGGTCATCGGCGCCGTCCGCAAGGAAGTTCAAACGCTCGACCGCAATCTGCTCTTGCA
GGCCGAGAGCTTGCAGGTTTCGATCCGCGATCTCTTGTGGGCCCAGCGCATCTCGGCCGGCCTGCTCGCCGCCTTCGGCT
TGCTCGCGCTCCTGCTCTCCAGCATCGGAATCTACGGCGTCGTCGCGTTCTCCGTCCGCCAGCGCACCCGTGAGATCGGC
GTCCGCATGGCAATGGGCGCGACCCCCGCCGACGTCCAGCTGATGATCGTGCGCGAAGGTGTCCGCCTGGTCGCGATCGG
CGTCCTCGCCGGCTTCGTCATCTCCTTCGCCGCAGCCGACAGCGTAGGCGGTATGCTCTTCATGAAGAACCCGCGCGACC
TCTTCACCTTCGCCTTGGTCCCGGCAATGCTTACCCTGGTCGGCATCCTCGCCTGCTGGGTCCCCGCCGCCCGCGCCATC
CGCATCGATCCGTCGATTGCGTTACGAGAGGAATAA

Upstream 100 bases:

>100_bases
AGCGCCGCAACCATAACCACCAGCAACGTTTTCGAGGTCACGAAATGCGAGTATAACAGTCCCATACGTACCGGCATGGG
TTATACTTGCTGGTTCCTGA

Downstream 100 bases:

>100_bases
ATCTTTTCTCGCAGAGCCGCGGAGCCGCAGAGTCACGCCAAGAAGATAAAGCCTTAGGAGTTTTGCATTGGTTTTCTCTG
CGTGACTCTGCGGCTCTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MTGILEDLRYGLRGLAKNRGFAVVAVLSLALGIGANTTIFTLLNAVFLRPLPVHDASSLVAVFTIDLRNPGLLNCSYPNY
RDYRDQNTVFSSLLLYTSVTVNLTGRGDPQLLMGQLVSGNFFNTLGVNPVLGRGFRPDEDASPGAAAVVVISHPLWQRLF
AGRPDVVGRPIELGGRTYSIVGVAPPGFVGLNQLIGADVFVPLSMYPQLYPAPAQVNQRSALMFSAVGRLKPGIGIAQAG
AAMRGLAQQLEREHPENRGRSLALTSISEAALSARTRPVISRAGAVLMTVSALILLIACGNVANLLLARAAGRNKEIAIR
LAMGATRPRLVRQLLTESLLLAFVGGALGLFLARWARDLLWGIRPATFNHAGFHLDLDPRVLLFTLGISVLTGVLFGLAP
ALRATKANLATDLKERAGVQSSFRYTWGLRATLVMAQVALSLIALIGAGLFVRSLQNAGQVDPGFDAVHLGIVAYNVTDQ
GYNEGRGRDFHERAVARAAAVPGVISASLAMDVPFHVAFSRKVVLEGQENTAQGRPTLTSVVSPGYLHTVAIPLLRGRDF
SPLDTKTTPRVAIVNEAAAAAFWPGRNPIGQRISFTTDRSPFEVIGVARNANYQAIDEAPQALVYLSLVQFYFPTAVLYV
HTAGDPTTVIGAVRKEVQTLDRNLLLQAESLQVSIRDLLWAQRISAGLLAAFGLLALLLSSIGIYGVVAFSVRQRTREIG
VRMAMGATPADVQLMIVREGVRLVAIGVLAGFVISFAAADSVGGMLFMKNPRDLFTFALVPAMLTLVGILACWVPAARAI
RIDPSIALREE

Sequences:

>Translated_811_residues
MTGILEDLRYGLRGLAKNRGFAVVAVLSLALGIGANTTIFTLLNAVFLRPLPVHDASSLVAVFTIDLRNPGLLNCSYPNY
RDYRDQNTVFSSLLLYTSVTVNLTGRGDPQLLMGQLVSGNFFNTLGVNPVLGRGFRPDEDASPGAAAVVVISHPLWQRLF
AGRPDVVGRPIELGGRTYSIVGVAPPGFVGLNQLIGADVFVPLSMYPQLYPAPAQVNQRSALMFSAVGRLKPGIGIAQAG
AAMRGLAQQLEREHPENRGRSLALTSISEAALSARTRPVISRAGAVLMTVSALILLIACGNVANLLLARAAGRNKEIAIR
LAMGATRPRLVRQLLTESLLLAFVGGALGLFLARWARDLLWGIRPATFNHAGFHLDLDPRVLLFTLGISVLTGVLFGLAP
ALRATKANLATDLKERAGVQSSFRYTWGLRATLVMAQVALSLIALIGAGLFVRSLQNAGQVDPGFDAVHLGIVAYNVTDQ
GYNEGRGRDFHERAVARAAAVPGVISASLAMDVPFHVAFSRKVVLEGQENTAQGRPTLTSVVSPGYLHTVAIPLLRGRDF
SPLDTKTTPRVAIVNEAAAAAFWPGRNPIGQRISFTTDRSPFEVIGVARNANYQAIDEAPQALVYLSLVQFYFPTAVLYV
HTAGDPTTVIGAVRKEVQTLDRNLLLQAESLQVSIRDLLWAQRISAGLLAAFGLLALLLSSIGIYGVVAFSVRQRTREIG
VRMAMGATPADVQLMIVREGVRLVAIGVLAGFVISFAAADSVGGMLFMKNPRDLFTFALVPAMLTLVGILACWVPAARAI
RIDPSIALREE
>Mature_810_residues
TGILEDLRYGLRGLAKNRGFAVVAVLSLALGIGANTTIFTLLNAVFLRPLPVHDASSLVAVFTIDLRNPGLLNCSYPNYR
DYRDQNTVFSSLLLYTSVTVNLTGRGDPQLLMGQLVSGNFFNTLGVNPVLGRGFRPDEDASPGAAAVVVISHPLWQRLFA
GRPDVVGRPIELGGRTYSIVGVAPPGFVGLNQLIGADVFVPLSMYPQLYPAPAQVNQRSALMFSAVGRLKPGIGIAQAGA
AMRGLAQQLEREHPENRGRSLALTSISEAALSARTRPVISRAGAVLMTVSALILLIACGNVANLLLARAAGRNKEIAIRL
AMGATRPRLVRQLLTESLLLAFVGGALGLFLARWARDLLWGIRPATFNHAGFHLDLDPRVLLFTLGISVLTGVLFGLAPA
LRATKANLATDLKERAGVQSSFRYTWGLRATLVMAQVALSLIALIGAGLFVRSLQNAGQVDPGFDAVHLGIVAYNVTDQG
YNEGRGRDFHERAVARAAAVPGVISASLAMDVPFHVAFSRKVVLEGQENTAQGRPTLTSVVSPGYLHTVAIPLLRGRDFS
PLDTKTTPRVAIVNEAAAAAFWPGRNPIGQRISFTTDRSPFEVIGVARNANYQAIDEAPQALVYLSLVQFYFPTAVLYVH
TAGDPTTVIGAVRKEVQTLDRNLLLQAESLQVSIRDLLWAQRISAGLLAAFGLLALLLSSIGIYGVVAFSVRQRTREIGV
RMAMGATPADVQLMIVREGVRLVAIGVLAGFVISFAAADSVGGMLFMKNPRDLFTFALVPAMLTLVGILACWVPAARAIR
IDPSIALREE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=293, Percent_Identity=29.6928327645051, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 86758; Mature: 86627

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGILEDLRYGLRGLAKNRGFAVVAVLSLALGIGANTTIFTLLNAVFLRPLPVHDASSLV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
AVFTIDLRNPGLLNCSYPNYRDYRDQNTVFSSLLLYTSVTVNLTGRGDPQLLMGQLVSGN
EEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCC
FFNTLGVNPVLGRGFRPDEDASPGAAAVVVISHPLWQRLFAGRPDVVGRPIELGGRTYSI
CCHHCCCCHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEECCCEEEE
VGVAPPGFVGLNQLIGADVFVPLSMYPQLYPAPAQVNQRSALMFSAVGRLKPGIGIAQAG
EEECCCCCHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHH
AAMRGLAQQLEREHPENRGRSLALTSISEAALSARTRPVISRAGAVLMTVSALILLIACG
HHHHHHHHHHHHHCCHHCCCEEEEHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCC
NVANLLLARAAGRNKEIAIRLAMGATRPRLVRQLLTESLLLAFVGGALGLFLARWARDLL
CHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIRPATFNHAGFHLDLDPRVLLFTLGISVLTGVLFGLAPALRATKANLATDLKERAGVQ
HCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SSFRYTWGLRATLVMAQVALSLIALIGAGLFVRSLQNAGQVDPGFDAVHLGIVAYNVTDQ
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCC
GYNEGRGRDFHERAVARAAAVPGVISASLAMDVPFHVAFSRKVVLEGQENTAQGRPTLTS
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECEEEEEECCCCCCCCCCCHHH
VVSPGYLHTVAIPLLRGRDFSPLDTKTTPRVAIVNEAAAAAFWPGRNPIGQRISFTTDRS
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCEEECCCCC
PFEVIGVARNANYQAIDEAPQALVYLSLVQFYFPTAVLYVHTAGDPTTVIGAVRKEVQTL
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHH
DRNLLLQAESLQVSIRDLLWAQRISAGLLAAFGLLALLLSSIGIYGVVAFSVRQRTREIG
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
VRMAMGATPADVQLMIVREGVRLVAIGVLAGFVISFAAADSVGGMLFMKNPRDLFTFALV
EEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
PAMLTLVGILACWVPAARAIRIDPSIALREE
HHHHHHHHHHHHHHCCCCEEEECCCEECCCC
>Mature Secondary Structure 
TGILEDLRYGLRGLAKNRGFAVVAVLSLALGIGANTTIFTLLNAVFLRPLPVHDASSLV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEE
AVFTIDLRNPGLLNCSYPNYRDYRDQNTVFSSLLLYTSVTVNLTGRGDPQLLMGQLVSGN
EEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCC
FFNTLGVNPVLGRGFRPDEDASPGAAAVVVISHPLWQRLFAGRPDVVGRPIELGGRTYSI
CCHHCCCCHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEECCCEEEE
VGVAPPGFVGLNQLIGADVFVPLSMYPQLYPAPAQVNQRSALMFSAVGRLKPGIGIAQAG
EEECCCCCHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHH
AAMRGLAQQLEREHPENRGRSLALTSISEAALSARTRPVISRAGAVLMTVSALILLIACG
HHHHHHHHHHHHHCCHHCCCEEEEHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCC
NVANLLLARAAGRNKEIAIRLAMGATRPRLVRQLLTESLLLAFVGGALGLFLARWARDLL
CHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIRPATFNHAGFHLDLDPRVLLFTLGISVLTGVLFGLAPALRATKANLATDLKERAGVQ
HCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SSFRYTWGLRATLVMAQVALSLIALIGAGLFVRSLQNAGQVDPGFDAVHLGIVAYNVTDQ
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCC
GYNEGRGRDFHERAVARAAAVPGVISASLAMDVPFHVAFSRKVVLEGQENTAQGRPTLTS
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECEEEEEECCCCCCCCCCCHHH
VVSPGYLHTVAIPLLRGRDFSPLDTKTTPRVAIVNEAAAAAFWPGRNPIGQRISFTTDRS
HCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCCEEECCCCC
PFEVIGVARNANYQAIDEAPQALVYLSLVQFYFPTAVLYVHTAGDPTTVIGAVRKEVQTL
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHH
DRNLLLQAESLQVSIRDLLWAQRISAGLLAAFGLLALLLSSIGIYGVVAFSVRQRTREIG
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
VRMAMGATPADVQLMIVREGVRLVAIGVLAGFVISFAAADSVGGMLFMKNPRDLFTFALV
EEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
PAMLTLVGILACWVPAARAIRIDPSIALREE
HHHHHHHHHHHHHHCCCCEEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA